Retinoic acid-induced 2 deficiency impairs genomic stability in breast cancer by Lena Boettcher, Sarah Greimeier, Kerstin Borgmann, Shabbir S. Mughal, Bernhard Ellinger, Kai Bartkowiak, Bernd Zobiak, Antonio V. Failla, Pascal Steffen, Ellen Claus, Katharina Besler, Christopher Buccitelli, Violetta Schaaf, Ann-Kathrin Ozga, Simona Parretta, Svenja Schneegans, Wael Y. Mansour, Jan O. Korbel, Hartmut Schlueter, Benedikt Brors, Klaus Pantel, Harriet Wikman, Stefan Werner

“…RAI2 was initially identified as a novel metastasis suppressor protein specifically associated with the presence of disseminated tumour cells in the bone marrow of breast cancer patients, but its molecular function is largely unknown. Methods We analysed the consequences of RAI2 depletion on gene expression and genomic stability in luminal breast cancer cell lines, performed cytotoxicity profiling using a library of pharmacologically active compounds, and characterized a potential function of the RAI2 protein in the DNA damage response. …”
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A novel plasma circular RNA circFARSA is a potential biomarker for non‐small cell lung cancer by Dong Hang, Jing Zhou, Na Qin, Wen Zhou, Hongxia Ma, Guangfu Jin, Zhibin Hu, Juncheng Dai, Hongbing Shen

“…Bioinformatics and functional analyses were performed to reveal biological effects of circRNAs on lung cancer cells. …”
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Automation of Optimization Synthesis for Modular Technological Equipment by Zaleta O. M., Povstyanoy O. Yu., Ribeiro L. F., Redko R. G., Bozhko T. Ye., Chetverzhuk T. I.

“…Technological equipment design based on functionally modular methods is widely used in various technical fields. …”
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OPTIMAL REACTIVE POWER FLOW SOLUTION OF 400-132 KV ELECTRIC NETWORKS OF IRAQ IN THE SOFTWARE PACKAGE RastrWin3 by A. Hussein, M. Zhukov, Y. Kononov

“…It is shown that the main effect is achieved by reducing losses in 132 kV lines. It is established that the network Q/V optimization module in the RastrWin3 does not take into account the change in transformer no-load losses and corona losses in overhead lines in the optimized function, which requires additional research to study their impact on optimization results.…”
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ESPN activates ZEB1-mediated EMT through the PI3K/AKT/mTOR axis to promote osteosarcoma metastasis by Ruikai Zhou, Hongyu Wu, Hao You, Xiaofei Wang, Xiuchen Yuan, Zhengyi Sun, Dong Zhou, Yuqing Jiang, Yifei Shen

“…The biological function of ESPN in osteosarcoma was confirmed by a series of experiments conducted both in vitro and in vivo. …”
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Theta-frequency subthalamic nucleus stimulation increases decision threshold by Rachel C. Cole, Nadja R. Ging-Jehli, Juan Vivanco Suarez, Jeremy D. Greenlee, Jan R. Wessel, Arturo I. Espinoza, Johnson Zhang, James F. Cavanagh, Nandakumar S. Narayanan

“…Introduction: Executive functions are often impaired in patients with Parkinson's disease (PD), and these deficits can be predicted by decreased frontal cortical 4–8 Hz theta activity that is associated with cognitive control. …”
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Sacral Fracture Causing Neurogenic Bladder: A Case Report by Tatsuro Sasaji, Noboru Yamada, Kazuo Iwai

“…Three months after surgery, his bladder function recovered normally. One year after surgery, he returned to a normal daily life and had no complaints regarding urination. …”
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BaCoN (Balanced Correlation Network) improves prediction of gene buffering by Thomas Rohde, Talip Yasir Demirtas, Sebastian Süsser, Angela Helen Shaw, Manuel Kaulich, Maximilian Billmann

“…BaCoN performance increases with more screens and genes considered, making it a valuable tool for gene buffering predictions from the growing DepMap.…”
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Simulation-based assessment of digital twin systems for immunisation by Leonardo de Oliveira El-Warrak, Claudio Miceli de Farias, Victor Hugo Dias Macedo De Azevedo Costa

“…To validate the system's performance and feasibility, simulations are conducted using SimPy, enabling the evaluation of its response under various operational scenarios.ResultsThe system facilitates the storage, monitoring, and visualisation of data related to the thermal conditions of ice-lined refrigerators (ILR) and thermal boxes. …”
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EDUCATIONAL TRAINING SIMULATOR FOR MONITORING READING TECHNIQUE AND SPEED BASED ON SPEECH-TO-TEXT (STT) METHODS by Olesia Barkovska, Heorhii Ivashchenko, Dmytro Rosinskiy, Daniil Zakharov

“…The results of testing children with dyslalia, meaning the rearrangement of sounds in words when reading, also showed that the Jaro algorithm has a shorter line comparison time for large text arrays (by 7%). …”
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Um estudo de usabilidade de sites de empresas virtuais Usability of virtual organization's sites by Simone Bacellar Leal Ferreira, Marie Agnes Chauvel, Denis Silva da Silveira

“…<br>This paper presents an analytical study of the non-functional requirement (NFR) usability with the objective of showing how they can interfere on the quality of a product. …”
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Healthy ageing for older adult people with intellectual disability: a scoping review by Nadia El Mrayyan, Marianne Holmgren, Gerd Ahlström

“…Our findings confirm the need to scale up healthy-ageing interventions in line with the WHO’s ambition to develop evidence-based approaches to optimise the functional capacity of all older people, including older adults with intellectual disability, by 2030. …”
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PTEN inhibits epithelial mesenchymal transition of thyroid cancer cells by regulating the Wnt/β-Catenin signaling pathway by Li Wei, Qianhui Liang, Chang Zhou, Rong Liu, Yun Liu

“…RT-qPCR and Western blot analyses were performed to quantify PTEN levels in the Nthy-ori 3–1 cell line and three THCA cell types (TPC-1, B-CPAP, FTC-133). …”
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Comparison of Skeletal, Dental, and Soft Tissue Changes Before and After Orthodontic Treatment in Patients with Congenitally Missing Bilateral Maxillary Lateral Incisors by Tuğba Şenel, Orhan Cicek

“…(1) <i>Background and Objectives</i>: Congenitally missing bilateral maxillary lateral incisors (CMBMLIs) present significant aesthetic, functional, and psychosocial challenges that require an orthodontic approach based on multidisciplinary consensus. …”
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Integrin mediated adhesion of osteoblasts to connective tissue growth factor (CTGF/CCN2) induces cytoskeleton reorganization and cell differentiation. by Honey Hendesi, Mary F Barbe, Fayez F Safadi, M Alexandra Monroy, Steven N Popoff

“…In this study, we used the MC3T3-E1 cell line to demonstrate that CTGF serves as an adhesive matrix for osteoblasts. …”
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Identification of Goat Supernumerary Teat Phenotype Using Wide-Genomic Copy Number Variants by Lu Xu, Weiyi Zhang, Haoyuan Zhang, Xiuqin Yang, Simone Ceccobelli, Yongju Zhao, Guangxin E

“…Supernumerary teats (SNTs) or nipples often emerge around the mammary line. This study performed a genome-wide selective sweep analysis (GWS) at the copy number variant (CNV) level using two selected signal calculation methods (<i>V</i>_ST and <i>F</i>_ST) to identify candidate genes associated with SNTs in goats. …”
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Diversity and Abundance of Breeding Birds, Habitat, and Nesting Substrate Selection in Urban Areas: A Relevant Case from the Southern Slope of the Mediterranean by Ikram Douini, Wafae Squalli, Ismail Mansouri, Mohamed Mounir, El-Mostafa Benka, Mohamed Dakki, Soumaya Hammada

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Downregulation of microRNA-145 may contribute to liver fibrosis in biliary atresia by targeting ADD3. by Yongqin Ye, Zhihan Li, Qi Feng, Zimin Chen, Zhouguang Wu, Jianyao Wang, Xiaoshuo Ye, Dahao Zhang, Lei Liu, Wei Gao, Lihui Zhang, Bin Wang

“…The Lentiviral vectors containing miR-145, miR-145-3p inhibitor, miR-145-5p inhibitor, empty vector were transfected into human hepatic stellate cell line (LX-2) to determine the functional effect of miR-145 on ADD3 expression at both mRNA and protein level.…”
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Probability of allogeneic hematopoietic stem cell transplant failure depending on the recipient's killer immunoglobulin-like receptor genotype by U. V. Maslikova, E. G. Khamaganova, M. Yu. Drokov, I. Yu. Urybin, E. D. Mikhaltsova, L. A. Kuzmina, E. N. Parovichnikova

“…Natural killers are the "first line" of antitumor and antiviral protection in the early stages after аllogeneic hematopoietic stem cell transplantation. …”
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Genetic overlap between sarcoidosis and lung cancer: a combined in silico and in vitro approach by Sanjukta Dasgupta, Moupiya Ghosh, Subhendu Chakrabarty, Gopal Chakrabarti, Amlan Das

“…Functional enrichment and protein–protein interaction (PPI) analyses were conducted using Enrichr and STRING, while associated miRNAs and transcription factors were identified via miRNet. …”
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