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1301
Estimating fish stock biomass using a Bayesian state-space model: accounting for catchability change due to technological progress
Published 2024-12-01“…This model allows for the flexible integration of the timing and functional form of the uptake of technological innovations that are assumed to influence catchability. …”
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1302
Exploring the prognostic significance and therapeutic potential of SUCLG2 in prostate cancer
Published 2025-07-01“…Furthermore, quantitative real-time polymerase chain reaction and immunofluorescence assays were performed to validate SUCLG2 expression in clinical samples and the prostate carcinoma epithelial cell line 22Rv1.ResultsOur findings revealed that lipid metabolism-related genes, including SUCLG2, have significant prognostic value, based on a 16-gene risk model constructed that accurately predicted PCa prognosis. …”
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1303
A domain-based framework for cognitive profile identification in Parkinson’s disease across diverse samples
Published 2025-06-01“…Five cognitive domains were constructed, addressing attention/working memory, executive functions, memory, visuospatial abilities, and language, using composite z-scores derived from standardized neuropsychological tests.ResultsLatent Cluster Analysis identified three distinct cognitive profiles: (1) a fronto-striatal profile characterized by mild deficits in executive and attention functions and intact visuospatial abilities, (2) a posterior cortical profile marked by severe memory and visuospatial impairments but strong language performance, and (3) a preserved profile displaying mild deficits across multiple domains. …”
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1304
Structural Parameter Identification Using Multi-Objective Modified Directional Bat Algorithm
Published 2025-01-01“…However, traditional single-objective optimization methods, which aggregate multiple evaluation indices into a single weighted objective function, often face challenges. The manual determination of weight factors introduces subjectivity, which can significantly affect the accuracy of the results. …”
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1305
PENGARUH PARAFFIN WAX SEBAGAI LAPISAN TANKI PADA AIR CONDITIONER WATER HEATER (ACWH)
Published 2024-12-01“…Currently air conditioner (AC) has been widely developed, one of which is the development of functions into two functions, namely air conditioning and providing hot water for bathing needs. …”
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1306
Loading Patterns of the Posterior Cruciate Ligament in the Healthy Knee: A Systematic Review.
Published 2016-01-01“…However, despite a number of experimental and modelling approaches to understand the kinematics and kinetics of the ligament, the normal loading conditions of the PCL and its functional bundles are still controversially discussed.…”
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1307
CUL4A as a marker and potential therapeutic target in multiple myeloma
Published 2017-07-01“…The expression of cullin 4A was detected by quantitative real-time polymerase chain reaction in multiple myeloma patients and multiple myeloma cell lines. In addition, silencing of cullin 4A with small interfering RNA was performed in human multiple myeloma cells, and the impact on proliferation, cell cycle, apoptosis, migration, and invasion of the multiple myeloma cells was analyzed. …”
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1308
Single-cell and spatial analyses of the GDF family in tumors, with a focus on the prognostic and biological role of GDF15 in hepatocellular carcinoma
Published 2025-06-01“…Moreover, both the gain and loss of function strategies were used to assess the function of Growth differentiation factor 15 (GDF15) in cell lines of HCC. …”
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1309
Pinching Sudakov
Published 2025-05-01“…We find their operator content in terms of matrix elements of Wilson lines on semi-infinite and finite intervals for the jet and ultrasoft functions, respectively. …”
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1310
Genetic dissection and validation of a new dominant QTL associated with chlorophyll content and its regulatory networks analysis in soybean
Published 2025-08-01“…To identify genes associated with chlorophyll content, we performed a large-scale linkage mapping study using recombinant inbred lines from a cross between the yl mutant and a green-leaf cultivar across three environments. …”
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1311
p53 inhibits OTUD5 transcription to promote GPX4 degradation and induce ferroptosis in gastric cancer
Published 2025-03-01“…To explore the physiological function of OUTD5, we knocked out the Otud5 gene in the mouse gastric cancer cell line (MFC) using CRISPR‐Cas9 and eatablished the subcutaneous tumour model. …”
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1312
The nuclear transcription factor ZmCCT positively regulates salt and low nitrogen stress response in Maize
Published 2025-06-01“…Under high salt and low nitrogen stress conditions, the Y331-ΔTE and 83B28H5/H5 inbred lines demonstrated superior phenotypic performance compared to the Y331 and 83B28H1/H1 lines. …”
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1313
Acute and subacute toxicity evaluation of ZhenzhuXiaoji decoction in preclinical models: implications for safe clinical use
Published 2025-04-01“…Acute and subacute toxicity studies were conducted in male and female mice, including assessments of behavioral changes, body weight, organ weight, and liver/kidney functions. Additionally, routine blood tests were performed to identify potential immunostimulatory effects.ResultsIn vitro experiments demonstrated that ZZXJD inhibited the proliferation of HHL-5 and HEK-293 cells in a dose-dependent manner and induced apoptosis and necrosis. …”
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1314
Tissue-resident immune cells in homeostasis and tissue repair
Published 2025-06-01“…Most types of immune cells are able to freely enter tissues, perform surveillance functions, and then leave them, while distinct cells are permanently located in non-lymphoid tissues. …”
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1315
Mixture of common and uncommon pathways and genes regulating primary and secondary immunoglobulin M responses in chickens
Published 2025-09-01“…Candidate genes were identified using a genome-wide association study (GWAS), and functional annotation analysis, protein-protein interaction network (PPIN), and colocalization analysis of the identified candidate genes were performed. …”
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1316
Feasibility of an exergaming training program in type 2 diabetes mellitus: A mixed method study
Published 2024-10-01“…Secondarily, possible effects on physical, functional, and patient-reported outcomes were explored. …”
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1317
Icreasing the efficiency of district heating supply systems by local heat distribution station modernation
Published 2022-06-01“…To consider the problems of functioning of an open heat supply system functioning. …”
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1318
Evaluation of 3D Nonlinear Earthquake Behaviour of the Ilısu CFR Dam under Far-Fault Ground Motions
Published 2019-01-01“…While defining these boundary conditions, the special fish functions are created and defined to the software. …”
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1319
An integrated alarm with clamp system to mitigate vascular access bleeding in hemodialysis: a prospective cohort mixed methods study
Published 2025-07-01“…Abstract Establishing and maintaining a functional vascular access is essential for patients with end-stage kidney disease on home hemodialysis. …”
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1320
Use of ICT to Confront COVID-19
Published 2021-06-01“…The risk of getting infected is a function of numerous factors where mathematical modeling would not yield fruitful results. …”
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