Ovarian tissue cryopreservation: a narrative review on cryopreservation and transplantation techniques, and the clinical outcomes by Zahra Karimizadeh, Zohreh Saltanatpour, Azadeh Tarafdari, Mahroo Rezaeinejad, Amir Ali Hamidieh

“…Under an acceptable medical condition and desirability, transplantation of cryopreserved tissue is performed either in orthotopic sites (orthotopic transplantation, OT) such as the original site of the ovaries and uterus, or heterotopic sites (heterotopic transplantation, HT) like abdominal wall, forearm, and peritoneal lining. …”
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Enhancement of bradykinin-induced relaxation by focal brain ischemia in the rat middle cerebral artery: Receptor expression upregulation and activation of multiple pathways. by Youhai Li, Natalia Lapina, Nina Weinzierl, Lothar Schilling

“…So far, these changes have mainly been related to alterations in the level of smooth muscle cell function while alterations of the endothelial lining have not yet been studied in detail. …”
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E2F8-induced GRPEL2 promoted colorectal cancer progression via targeting TIGAR by Cheng Song, Lei Zhao, Jing Deng, Li Wang, Min Mao, Siyuan Peng, Wei Tang

“…GRPEL2 is a critical regulator of mitochondria’s function with an oncogenic role in different kinds of cancer. …”
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Fine mapping of a major QTL on chromosome A05 conferring pod size in peanut by Kunkun Zhao, Xufa Du, Jingjing Zhang, Yi Fan, Qian Ma, Yaoyao Li, Zenghui Cao, Di Cao, Sasa Hu, Ding Qiu, Kai Zhao, Fangping Gong, Zhongfeng Li, Rui Ren, Lin Zhang, Xingli Ma, Xingguo Zhang, Dongmei Yin

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Analysis of risk factors linked to social educator profession in different residential settings of Alicante Province by Jorge Heliz Llopis, Ignasi Navarro Sória, Noelia Tortosa Casado, Pablo Jodra Jiménez

“….), social educators are the ones who, through the carrying out of functions specific to their profession, often work as the "front line" of action, given that they are the ones who are more in touch with the underage and therefore the most likely to be exposed to different variables that could eventually put them in a situation of risk of psycho-social problems related to their work. …”
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Applying Gene Expression Programming for Solving One-Dimensional Bin-Packing Problems by Najla Al-Saati

“…This work aims to study and explore the use of Gene Expression Programming (GEP) in solving on-line Bin-Packing problem. The main idea is to show how GEP can automatically find acceptable heuristic rules to solve the problem efficiently and economically. …”
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Artificial Intelligence Sexual Innovation and the Marriage Covenant: An Ethical and Theological Assessment by Brian Kapembwa Sinyangwe

“…A topical moral discussion lies in the development of sexual robots that can perform conjugal functions. However, the Bible presents the concept of sexuality as a privilege exercised within the precincts of the same species in heterosexual relationships. …”
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Identification and Validation of Autophagy-Related Genes in Primary Ovarian Insufficiency by Gene Expression Profile and Bioinformatic Analysis by Siji Lv, Jiani Sun, Jing Sun

“…Bioinformatics analysis was performed to observe the features of hub genes, including hub gene-RBP/TF/miRNA/drug network construction, functional analysis, and protein-protein interaction network. …”
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Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy by Junyan Wang, Panpan Sun, Fan Zhang, Yu Xu, Shenghu Guo

“…IntroductionSmall cell lung cancer (SCLC) remains a leading cause of cancer mortality worldwide, characterized by rapid progression and poor clinical outcomes, and the function of metabolic reprogramming remains unclear in SCLC.MethodsWe performed multi-omics analysis using public SCLC datasets, analyzing single-cell RNA sequencing to identify metabolic reprogramming patterns between chemotherapy-resistant and sensitive samples. …”
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Applying integrated transcriptome and single-cell sequencing analysis to develop a prognostic signature based on M2-like tumor-associated macrophages for breast cancer by Yanghaochen Xu, Peiyan Lin, Ye Zhu, Qing Zhang, Jinhong Zhou

“…Abstract Background M2-like tumor-associated macrophages (M2-like TAMs) function crucially in the tumor microenvironment (TME) and cancer development. …”
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Gut microbiome and metabolome interactions in Crohn’s disease: mechanistic insights into exclusive enteral nutrition-induced remission by Weiwei Zheng, Weiwei Zheng, Weiwei Zheng, Weiwei Zheng, Quan Zhou, Quan Zhou, Mengli Xue, Mengli Xue, Mengli Xue, Mengli Xue, Xing Yu, Xing Yu, Xing Yu, Xing Yu, Xue’e Chen, Xue’e Chen, Xue’e Chen, Xue’e Chen, Jintong Chen, Jintong Chen, Jintong Chen, Jintong Chen, Chengdang Wang, Chengdang Wang, Chengdang Wang, Chengdang Wang

“…The composition of the gut microbiome was analyzed through 16S rRNA gene sequencing, while metabolomic profiling was conducted using liquid chromatography–mass spectrometry (LC–MS). Functional analysis of microbial pathways was performed utilizing the KEGG Orthology (KO) and MetaCyc databases.ResultsEEN therapy induced significant structural shifts in the gut microbiome, including a reduction in the abundance of pro-inflammatory bacteria such as Fusobacterium and Veillonella. …”
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20(S)-Ginsenoside Rh2 overcomes gemcitabine resistance in pancreatic cancer by inhibiting LAMC2-Modulated ABC transporters by Yulin Wu, Juan Zhang, Yuanyang Tian, William Chi Shing Cho, Hong-Xi Xu, Zhi-Xiu Lin, Yan-Fang Xian

“…Introduction: Gemcitabine (GEM) is the first-line drug for pancreatic ductal adenocarcinoma (PDAC), but drug resistance severely restricts its chemotherapeutic efficacy. …”
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Aripirazole and Cognitive Behavioral Therapy in Adolescents with Obsessive-Compulsive Disorder: Case Study by Sevim Berrin INCI, Ulku AKYOL ARDIC, Melis IPCI, Eyup Sabri ERCAN

“…Cognitive behavioral therapy and seratonin reuptake inhibitors are first-line treatment for OCD. In this case we studied the association of cognitive behavioral therapy and aripiprazole treatment. …”
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The VDAC3/DHODH Axis Ameliorates Sepsis-induced Myocardial Injury by Regulating Ferroptosis by Jiali Wang, Fan Zhang, Chaoqing Tan, Nana Wang, Xuexia Xia, Yun Ye, Yue Cao, Xin Huang, Zhenjiang Bai, He Zhao, Ling Sun, Qiuqin Xu, Huiting Zhou, Jie Huang

“…Echocardiography was used to evaluate the structural and functional characteristics of the heart. Integrated transcriptome and proteomic studies were performed to identify differentially expressed genes. …”
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Pan-cancer analysis shows that BCAP31 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types by Yangyong Sun, Zhi Li, Jianchao Liu, Ying Xiao, Yaqiang Pan, Benbo Lv, Xufeng Wang, Zhiqiang Lin

“…Furthermore, BCAP31 expression impacted the outcomes and prognosis of cancer patients undergoing immune therapy. The functional assays demonstrated that BCAP31 knockdown in KYSE-150 cells significantly inhibited cell migration, invasion, and proliferation while enhancing colony formation ability. …”
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Mesenchymal stem cells derived from hPSC via neural crest attenuate chemotherapy-induced premature ovarian insufficiency by ameliorating apoptosis and oxidative stress in granulosa... by Xinran Li, Jinrong Liao, Youhong Zheng, Wei Cai, Jie Chen, Yu Liang, Yuanmei Chen, Xiaoxuan Li, Jiamao Luo, Jiaxin Xie, Manping Zhou, Lilin Hang, Xiujuan Sun, Xin Yue, Xuefeng Wang, Yifeng Wang, Huiyan Wang

“…Systematic characterization of differentiated-cells was performed using qPCR, immunofluorescence, cell viability assays, flow cytometry and trilineage differentiation. …”
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Aldo-keto Reductase 1B10 (AKR1B10) Suppresses Sensitivity of Ferroptosis in TNBC by Activating the AKT/GSK3β/Nrf2/GPX4 Axis by Shanli Wu, Gun Yang, Xiaosha Wen, Yi Lin, Shenglong Wang, Jing Wang, Quan Liu, Dixian Luo

“…Several studies have highlighted the essential function of AKR1B10 in lipid metabolism and in the detoxification of lipid peroxides. …”
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Evaluating oxidative stress targeting treatments in in vitro models of placental stress relevant to preeclampsia by Dinara Afrose, Matt D. Johansen, Matt D. Johansen, Valentina Nikolic, Natasa Karadzov Orlic, Natasa Karadzov Orlic, Zeljko Mikovic, Zeljko Mikovic, Milan Stefanovic, Milan Stefanovic, Zoran Cakic, Philip M. Hansbro, Philip M. Hansbro, Lana McClements, Lana McClements

“…Placental dysfunction is a hallmark feature of preeclampsia, which is often caused by inappropriate trophoblast cell function in association with oxidative stress, inflammation and/or pathological hypoxia. …”
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A systematic investigation of differential effects of cell culture substrates on the extent of artifacts in single-molecule tracking. by Laura C Zanetti-Domingues, Marisa L Martin-Fernandez, Sarah R Needham, Daniel J Rolfe, David T Clarke

“…Linear PEG, a passivating agent commonly used both in immobilized-molecule single-molecule techniques and in tissue engineering, is able to both successfully repel non-specific adhesion of fluorescent probes and to foster cell growth when functionalized with appropriate adhesive peptides. Linear PEG treatment results in a significant reduction of tracking artifacts in EGFR tracking with Affibody ligands on a cell line expressing EGFR-eGFP. …”
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Adaptive quadrilateral distance relaying scheme for fault impedance compensation by Patel Ujjaval J., Chothani Nilesh G., Bhatt Praghnesh J.

“…Moreover, the proposed technique provides significant improvement in response time and estimation of fault location as compared to existing distance relaying algorithms, which are the key attributes of multi-functional numerical relay…”
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