3D Global Weak-Form Mesh-Free Method for Acoustic Attenuation Analysis of Expansion Chambers by Chun-Hui Fang, Cheng-Yang Liu, Zhi Fang

“…Additionally, the effects of axial modes on the acoustic characteristics are investigated, and the pass through frequencies can be eliminated to enhance the acoustic attenuation performance by locating the side branch outlet on the nodal lines of axial modes.…”
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Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL‐AD preclinical testing core study by Kristen D. Onos, Sara K. Quinney, David R. Jones, Andrea R. Masters, Ravi Pandey, Kelly J. Keezer, Carla Biesdorf, Ingrid F. Metzger, Jill A. Meyers, Johnathon Peters, Scott C. Persohn, Brian P. McCarthy, Amanda A. Bedwell, Lucas L. Figueiredo, Zackary A. Cope, Michael Sasner, Gareth R. Howell, Harriet M. Williams, Adrian L. Oblak, Bruce T. Lamb, Gregory W. Carter, Stacey J. Sukoff Rizzo, Paul R. Territo

“…Methods A multi‐tier approach was applied that included quality assurance and quality control of the active pharmaceutical ingredient, PK/PD modeling, positron emission tomography/magnetic resonance imaging (PET/MRI), functional outcomes, and transcriptomics. 5XFAD mice were treated chronically with LEV for 3 months at doses in line with those allometrically scaled to the clinical dose range. …”
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Necrotic and Inflammatory Changes on Acute Studies of Siam Leaf (Chromolaena Odorata) Alcoholic Extract on Lead Induced Toxicity of Cardio-Pulmonary Morphology of Adult Albino Wist... by Ilegbedion, I.G.1*, Beredugo, S.,2 Aturaka, O.S.3, Tabowei, W.T.4.

“…Long-term exposure of adults can result in decreased performance in some tests of cognitive performance that measure functions of the nervous Cardio-pulmonary system.  …”
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Title of the study: finite element analysis of five internal fixation modalities for Schatzker type IV‒C tibial plateau fractures by Zulong Zhou, Run Fang, Yulong Liu, Mingxiang Liu, Lingchao Kong, Rende Ning

“…However, balance the benefits against increased complexity, particularly in patients with compromised soft tissue or high functional demands. Selecting internal fixation based on the fracture line can optimize outcomes and speed recovery.…”
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starkiller: Subtracting Stars and Other Sources from IFU Spectroscopic Data Through Forward Modeling by Ryan Ridden-Harper, Michele T. Bannister, Sophie E. Deam, Thomas Nordlander

“…We present starkiller , an open-source Python package for forward-modeling flux retrieval from integral field unit (IFU) spectrograph data cubes. starkiller simultaneously provides stellar spectral classification, relative velocity, and line-of-sight extinction for all sources in a catalog, alongside a source-subtracted data cube. …”
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Clinical outcomes of transarterial chemoembolization combined with durvalumab for advanced and metastatic biliary tract cancer by Yuefeng Hu, Jian Wei, Xuedong Sun, Guang Chen, Tianhao Su, Zeran Yang, Xu Lu, Long Jin

“…The TACE procedures were performed 1 to 19 times, with repetitions occurring every 4 to 12 weeks based on the patient’s liver function and tumor shrinkage. …”
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SAP30 deacetylates the Tas protein to inhibit PFV replication by Chenchen Wang, Junshi Zhang, Yali Xu, Jiawei Zhao, Manman Qiu, Xingli Zhao, Guoqiang Li, Wentao Qiao, Juan Tan

“…Results To identify new host proteins involved in the replication of prototype foamy virus (PFV), we previously infected the human fibrosarcoma cell line HT1080 with PFV and performed transcriptomic sequencing. …”
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miR-142-3p Modulates Cell Invasion and Migration via PKM2-Mediated Aerobic Glycolysis in Colorectal Cancer by JunYu Ren, Wenliang Li, Guoqing Pan, Fengchang Huang, Jun Yang, Hongbin Zhang, Ruize Zhou, Ning Xu

“…Decreased expression of miR-142-3p was observed in human cancers. However, the function and mechanism of miR-142-3p in human colorectal cancer remain obscure. …”
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A Lumbar Drug-Resistant Tuberculosis: A Case Report and Review of Literature by Li T, Liu S

“…However, spinal multi-drug resistant tuberculosis (MDR-TB) in patients with normal immune function is a disease that is prone to misdiagnosis and even delayed diagnosis. …”
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Development of an Immunodeficient Pig Model for Pancreatic Cancer Xenotransplantation Using Splenectomy, Thymectomy, and Oral Immunosuppression by Jun Suh Lee, Yoo-Seok Yoon, Ho-Seong Han, Jai Young Cho, Hae-Won Lee, Boram Lee, Yeshong Park, MeeYoung Kang

“…After introduction into the animal laboratory, splenectomy and thymectomy were performed to minimize B-cell and T-cell function. One week after the initial operation, oral immunosuppression was administered. …”
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LncRNA16 inhibits pyroptosis and promotes platinum resistance in non-small cell lung cancer by sponging miRNA1827 to regulate MBD3/GSDME expression by Yanfang Liu, Yuanjun Zeng, Sikai Wang, Jiangyan Chen, Zhouqi Wang, Yang Zhao, Kuiyu Gong, Guihua Wang

“…Methods The biological roles of lncRNA16 and microRNA 1827 (miRNA1827) in cell proliferation and colony formation were determined using functional experiments. Dual-luciferase reporter and RNA immunoprecipitation assays were performed to confirm the interactions between lncRNA16 and miRNA1827. …”
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Simulation and reconstruction of parameters of streamflow and glacier mass balance in the Northern Caucasus by V. G. Konovalov

“…Use of all obtained information made possible the following results: a) new formulas for the calculation of seasonal runoff of the Terek river at the seven gauging stations for 1901–2010 years were derived and verified with independent data; b) significance of various arguments in these formulas was assessed to describe variability of function; c) for the first time relationships between the equilibrium line altitude (ELA), the index of area of accumulation (AAR), and components of the mass balance of the glaciers Djankuat and Garabashi were obtained; d) a technique for regional calculation of average accumulation on these glaciers was developed by using data on ablation and ELA.…”
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Metformin reverses 5-FU resistance induced by radiotherapy through mediating folate metabolism in colorectal cancer by Shuxuan Wang, Yanyan Lin, Qianqian Zhao, Huanliang Chen, Shisuo Du, Zhaochong Zeng

“…Results The conventional fractionation scheme (2 Gy × 8) induced resistance to 5-FU in the CRC cell line HCT-15, accompanied by an elevated RNA expression level of peptidase HM13. …”
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<i>IGFBP5</i> Promotes Atherosclerosis in APOE^−/− Mice Through Phenotypic Transformation of VSMCs by Aoqi Xiang, Hua Guan, Peihong Su, Lusha Zhang, Xiaochang Chen, Qi Yu

“…Analysis of <i>IGFBP5</i> function using RNA sequencing and validation were performed in a mouse aortic smooth muscle cell line. …”
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Low-dose trimethoprim-sulfamethoxazole for prophylaxis of Pneumocystis jirovecii pneumonia in HIV-uninfected patients: a systematic review and meta-analysis by Hui-Bin Huang, Jia-Heng Shi, Yan-Ge Hu, Yi-Bing Zhu, Da-Xing Yu

“…BackgroundTrimethoprim-sulfamethoxazole (TMP-SMX) is the recommended first-line prophylactic agent against Pneumocystis jirovecii pneumonia (PJP). …”
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RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma by Alan Chu, Xiao Liu, Shijia Liu, Mengxi Li, Rui Song, Lanlan Gan, Yongtai Wang, Zongwen Liu, Chen Sun

“…The stable transfected TE-1 cell line with knockdown of the APE1 gene was successfully constructed, with a knockdown efficiency of 100%. …”
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Metabolic and nutritional effects of vitamin A on growth, lipid metabolism, antioxidant capacity and hepatopancreas health of juvenile mud crab (Scylla paramamosain) by Zheng Tang, Shichao Xie, Yao Deng, Wenhao Zhan, Hongyu Peng, Yinqiu Tian, Haiqing Cao, Min Jin, Binjie Zhou, Yushan Zou, Juntao Gu, Peng Sun, Qicun Zhou

“…The correlation analysis results showed that fatp4 and gpx both have a significant positive correlation with growth performance related parameters, suggesting they may be crucial for VA's physiological functions. …”
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Effects of the number of ethylene glycol units on the efficacy of novel complex I inhibitor 9bw by Kazuaki Sekimoto, Hanaka Kinjo, Mizuki Murakami, Akiko Ohashi, Rei Fukui, Eri Nagasaki-Maeoka, Yoshinori Inagaki, Tadateru Takayama, Kazuhiro Ikeda, Ken-ichi Takayama, Satoshi Inoue, Motonori Tsuji, Joe Otsuki, Kyoko Fujiwara

“…To clarify the molecular structure critical for 9bw′s function, we tested the function of 9bw analogues on human oral squamous cell carcinoma lines HSC4 and Ca9-22. …”
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Development of Experimental Setup to Investigate the Control System for Infusion Solutions Dosing Process by Fedir Matiko, Volodymyr Shaleva

“…Research on the selected programmable logic controller and the dosing process control system was performed. The results of research confirmed that using CPU 1215C DC/DC/DC controller, it is possible to achieve the same speed and productivity of the dosing line as when using control systems based on single-chip processors, while significantly expanding the functional capabilities of the system. …”
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Dynamic Analysis of Metro Train-Monolithic Bed Track System under Tunnel Differential Settlement by Jiqing Jiang, Beibei Dong, Zhi Ding, Gang Wei, He Zhang, Juan Liao

“…In this paper, a dynamic coupling model for a metro train-monolithic bed track system under tunnel differential settlement is established. A cosine function is introduced to simulate a real settlement curve measured from a metro tunnel in southern China, and the vibration performance of the train-track system under tunnel settlements is investigated in both the time domain and frequency domain. …”
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