-
1621
A Wearable Soft Actuator for Directional Tactile Stimulation: Design and Testing
Published 2025-08-01“…The actuator's design considers functional requirements like weight, actuation speed, and stroke length, as well as human skin mechanics. …”
Get full text
Article -
1622
Broadening the lens: A review of multi-object tracking task and its use in cognitive training
Published 2025-08-01“…This narrative review synthesizes existing research on how adjustable MOT parameters, such as target number, object speed, tracking duration, and perceptual features, influence performance and transfer outcomes across populations.This narrative review aims to (1) identify the cognitive functions engaged by various MOT parameters, (2) determine which adaptations lead to performance gains, and (3) assess how MOT improvements translate into near and far transfer effects, with a focus on real-world applications.MOT involves divided and sustained attention, foveal and peripheral vision, and inhibitory control, interacting with working memory and executive functions, which encompass high-level cognitive processes such as planning, inhibition, and cognitive flexibility. …”
Get full text
Article -
1623
Neural correlates of emotional working memory predict depression and anxiety
Published 2025-05-01“…Understanding how emotional stimuli, particularly negative ones, affect WM performance is crucial for identifying cognitive markers of mental health issues like anxiety and depression. …”
Get full text
Article -
1624
Abnormal α-synuclein binds to synaptotagmin 13, impairing extracellular vesicle release in synucleinopathies
Published 2025-06-01“…Abstract Background Despite increasing in vitro research, direct evidence of how abnormal α-synuclein (α-Syn) dysregulates vesicular transport and synaptic function in the human brain is lacking. Methods We performed a transcriptome analysis using brain tissues from a multiple system atrophy (MSA) mouse model, which develops human α-Syn-positive glial cytoplasmic inclusion-like structures and neuronal cytoplasmic inclusion-like structures after tamoxifen injection. …”
Get full text
Article -
1625
Feature engineering through two-level genetic algorithm
Published 2025-09-01“…For each training set, the features were expanded using seven non-linear transformation functions, and the minimum feature set maximizing ensemble model performance was selected using the Non-Dominated Sorting Genetic Algorithm II (NSGA-II). …”
Get full text
Article -
1626
Synthesis and characterization of hybrid nanocomposite core (polymer)-shell metal-organic frame-works based on SAN, Zn and Al nanoparticles
Published 2025-07-01“…The core-shell porous polymer-metal-organic framework (MOF) hybrid nanostructures exhibit unique characteristics compared to traditional core-shell nanocomposites, especially in terms of synthesis strategy, structural integration, functionality, and performance. The crucial innovations of the calcination step and carboxylic acid activation set these hybrids apart from previous polymer-MOF composites, which often relied on weak electrostatic interactions or complex covalent functionalization. …”
Get full text
Article -
1627
Multi-omics reveal the neuroprotective mechanisms of Xinshubao tablet against scopolamine-induced cognitive dysfunction in mice
Published 2025-07-01“…Then, fecal 16S rDNA sequencing, serum metabolomics, and hippocampal mRNA sequencing (mRNA-seq) analysis were performed to investigate the underlying mechanisms.Results and discussionThe results revealed that oral administration of XSB improved cognitive function, mitigated neuropathological damage, and alleviated dysfunction in the cholinergic system in AD-like mice. …”
Get full text
Article -
1628
Ionic liquid-assisted biomass-derived N, S-doped carbon dots with enhanced corrosion inhibition
Published 2025-07-01“…The IL increased the content of pyrrole-like nitrogen and C-SOx group, facilitating the formation of a denser protective film. …”
Get full text
Article -
1629
Opportunities, challenges and future perspectives of using bioinformatics and artificial intelligence techniques on tropical disease identification using omics data
Published 2024-11-01“…Furthermore, recent advancements including Transformer-based models such as BERT and GPT-4, have been mainly applied for sequence analysis and functional genomics. Finally, the most recent GeneViT model, utilizing Vision Transformers, and other AI techniques like Generative Adversarial Networks, Federated Learning, Transfer Learning, Reinforcement Learning, Automated ML and Attention Mechanism have shown significant performance in disease classification using omics data.…”
Get full text
Article -
1630
5-HT2A Receptor Binding in the Frontal Cortex of Parkinson’s Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study
Published 2016-01-01“…The 5-HT2A receptor is highly involved in aspects of cognition and executive function and seen to be affected in neurodegenerative diseases like Alzheimer’s disease and related to the disease pathology. …”
Get full text
Article -
1631
A Parametric Analysis of the Effect of Hybrid Nanoparticles on the Flow Field and Homogeneous-Heterogeneous Reaction between Squeezing Plates
Published 2022-01-01“…To check the validity of the results obtained from the shooting mode, the Matlab built-in function BVP4c and Mathematica built-in function homotopy analysis method (HAM) are used. …”
Get full text
Article -
1632
Knockout of AMPA receptor binding protein Neuron-specific gene 2 (NSG2) enhances associative learning and cognitive flexibility
Published 2024-12-01“…For instance, NSG2 KO animals performed equivalent to wild-type C57Bl/6n mice on rotarod and Catwalk motor tasks, and did not display alterations in anxiety-like behavior on open field and elevated zero maze tasks. …”
Get full text
Article -
1633
Urobilin Derived from Bilirubin Bioconversion Binds Albumin and May Interfere with Bilirubin Interacting with Albumin: Implications for Disease Pathology
Published 2025-01-01“…We hypothesized that because of the likeness of their chemical structures, urobilin would also bind albumin like bilirubin does. …”
Get full text
Article -
1634
To study the burden of post tubercular obstructive airway diseases in patients visiting chest OPD at a tertiary level chest OPD in North India: a descriptive cross-sectional study
Published 2025-06-01“…The mean latency of COPD symptoms after completion of ATT was found to be 5.38 ± 6.77 years.Conclusion: Post-tuberculosis subjects presented with lung function decline without confounding factors like smoking; thus, early screening of COPD is required once diagnosed; appropriate treatment should be initiated as early detection and treatment of these patients can help in better disease management and optimum treatment outcomes.…”
Get full text
Article -
1635
Sleep disorders and Alzheimer’s disease: relationship and mechanisms involving neuroinflammation, orexin and Aβ
Published 2025-06-01“…Comparisons were made between the two groups in cognitive function, neuroinflammatory factors, orexinergic factors and AD biomarkers in cerebrospinal fluid (CSF). …”
Get full text
Article -
1636
Laser Sintering of Nano-Graphite-Reinforced Polyamide Composites for Next-Generation Smart Materials: A Preliminary Investigation of Processability and Electromechanical Properties
Published 2025-05-01“…Multifunctional reinforced polymer composites provide an ideal platform for next-generation smart materials applications, enhancing matrix properties like electrical and thermal conductivity. Reinforcements are usually based on functional metal alloys, inorganic compounds, polymers, and carbon nanomaterials. …”
Get full text
Article -
1637
Yeast culture in weaned lamb feed: a proteomic journey into enhanced rumen health and growth
Published 2025-08-01“…Yeast culture upregulated the insulin-like growth factor-1 receptor (IGF-1R) and insulin-like growth factor-binding protein 5 (IGFBP-5) mRNA expressions in rumen epithelial cells. …”
Get full text
Article -
1638
A Review of Health Monitoring and Model Updating of Vibration Dissipation Systems in Structures
Published 2025-01-01“…However, many studies have investigated the dissipating energy capacity of isolation systems, particularly rubber bearings with different damping ratios, and demonstrated that changes in these parameters affect the seismic performance of structures. The main objective of this review is to evaluate the performance of damage detection computational tools and examine the impact of damage on structural functionality. …”
Get full text
Article -
1639
Effects of the Interaction Between Time-on-Task and Task Load on Response Lapses
Published 2024-11-01“…Dependent variables included measures of fatigue, arousal, workload, task performance (delayed and error rates), and brain functional connectivity. …”
Get full text
Article -
1640
Model-free reconstruction of excitatory neuronal connectivity from calcium imaging signals.
Published 2012-01-01“…Thus by conditioning with respect to the global mean activity, we improve the performance of our method. This allows us to focus the analysis to specific dynamical regimes of the network in which the inferred functional connectivity is shaped by monosynaptic excitatory connections, rather than by collective synchrony. …”
Get full text
Article