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  1. 821
  2. 822

    Optimizing Conservative Treatment for Femoroacetabular Impingement Syndrome: A Scoping Review of Rehabilitation Strategies by Federica Giorgi, Daniela Platano, Lisa Berti, Danilo Donati, Roberto Tedeschi

    Published 2025-03-01
    “…While surgery is generally not performed in individuals under 18 due to skeletal immaturity, it remains a standard treatment option for adults presenting with persistent symptoms and functional limitations. …”
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  3. 823

    Inhibition of TGF-β-receptor signaling augments the antitumor function of ROR1-specific CAR T-cells against triple-negative breast cancer by Michael Hudecek, Achim Wöckel, Jörg Wischhusen, Tanja Stüber, Razieh Monjezi, Lars Wallstabe, Johanna Kühnemundt, Sarah Louise Nietzer, Gudrun Dandekar, Hermann Einsele

    Published 2020-05-01
    “…Here, we analyzed whether CAR T-cells specific for the receptor tyrosine kinase-like orphan receptor 1 (ROR1) antigen, that is frequently expressed in triple-negative breast cancer (TNBC), are susceptible to inhibition by TGF-β and evaluated TGF-β-receptor signaling blockade as a way of neutralizing the inhibitory effect of this cytokine.Methods CD8+ and CD4+ ROR1-CAR T-cells were prepared from healthy donors and their antitumor function analyzed using the TNBC cell line MDA-MB-231 in vitro and in a microphysiologic 3D tumor model. …”
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  4. 824

    Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins. by José Luis González-Guerra, Inma Castilla-Cortazar, Gabriel A Aguirre, Úrsula Muñoz, Irene Martín-Estal, Elena Ávila-Gallego, Miriam Granado, Juan E Puche, Ángel Luis García-Villalón

    Published 2017-01-01
    “…In addition, histology of the heart was performed together with cardiac gene expression for proteins involved in structure and function (extracellular matrix, contractile proteins, active peptides); carried out using microarrays, followed by RT-qPCR confirmation of the three experimental groups. …”
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  5. 825

    A synergistic blend of dietary organic acids, monoglycerides and phytobiotics enhance growth performance, intestinal mucosal height, and anti-viral immune gene expression in juveni... by Charlene Goh, Susan Gibson-Kueh, David Bal, I.-Tung Chen, Waldo Nuez-Ortín, Jose A. Domingos, Xueyan Shen

    Published 2025-04-01
    “…Recent findings suggest that functional diets provide a broader advantage over the pathogen-specific protection of vaccines by improving growth performance, gut health, and immunity in teleosts. …”
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  6. 826

    EFFECT OF FUROSTANOL GLYCOSIDES FROM CULTURED DIOSCOREA DELTOIDEA CELLS ON REGULATORY FUNCTION OF ENDOTHELIUM IN A RAT MODEL OF HYPOESTROGEN-INDUCED ENDOTHELIAL DYSFUNCTION by E. B. Artyushkova, N. G. Gumanova, V. A. Metelskaya, T. G. Pokrovskaya, V. I. Kochkarov, M. V. Korokin, M. V. Pokrovsky, L. V. Korokina, A. M. Nosov, M. M. Korneev

    Published 2016-01-01
    “…Treatment with plant origin substances with estrogen-like activity can be a perspective approach to the correction of endothelial function and decrease in cardiovascular risk in menopause women.…”
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  7. 827

    <i>In vitro</i> functional activity of T lymphocytes under the conditions of ‘cell neighborhood’ of proliferating and apoptotic cells in healthy people and patients with rheumatoid... by T. Ya. Abramova, E. A. Blinova, E. A. Pashkina, L. V. Grishina, N. A. Ilina, O. A. Chumasova, A. E. Sizikov, V. A. Kozlov

    Published 2024-11-01
    “…The results of the analysis, with respect to previous data, revealed both similar and different functions of the T cell systems generated under “cell-neighborhood” conditions in healthy individuals and RA patients. …”
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  8. 828

    The clinico-radiological paradox of cognitive function and MRI burden of white matter lesions in people with multiple sclerosis: A systematic review and meta-analysis. by Daisy Mollison, Robin Sellar, Mark Bastin, Denis Mollison, Siddharthan Chandran, Joanna Wardlaw, Peter Connick

    Published 2017-01-01
    “…<h4>Background</h4>Moderate correlation exists between the imaging quantification of brain white matter lesions and cognitive performance in people with multiple sclerosis (MS). …”
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  9. 829

    Elimination of hepatocyte‐derived DPP4 downregulates cardiac immune‐ and collagen‐related genes but does not alter cardiac function in aged male mice by Natasha A. Trzaskalski, Melissa M. Dann, Antonio Hanson, Branka Vulesevic, Evgenia Fadzeyeva, Natasha Jeraj, Ilka Lorenzen‐Schmidt, Rick Seymour, Erin E. Mulvihill

    Published 2025-08-01
    “…This study evaluates how diastolic function and molecular signatures of heart failure, like inflammation and fibrosis, are affected in male Dpp4+/+, Dpp4−/−, and Dpp4flox/flox mice injected with a TBG‐CRE to selectively eliminate DPP4 from hepatocytes (Dpp4hep−/−) and respective controls (Dpp4GFP), aged and fed an HFHC diet for 24 weeks. …”
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  10. 830
  11. 831

    Effect of dual task-based training on motor and cognitive function in stroke patients: a systematic review and meta-analysis of randomized controlled trails by Chuan Mou, Yundi Jiang

    Published 2025-07-01
    “…The study found that compared with the control group, dual-task cognitive motor training can improve the walking performance of stroke patients (WMD = 3.19, 95%CI: 2.26, 4.12), the recovery of lower limb motor function (WMD = 2.78, 95% CI: 1.38, 4.18), cognitive function (WMD = 2.93, 95% CI: 0.95, 4.91) and mental state (WMD = 3.39, 95% CI: 0.06, 6.72), and the functional state of activities of daily living (WMD = 7.47, 95% CI: 3.97, 10.96). …”
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  12. 832

    Same same but different: Neuroanatomic and connectomic profiles of early-onset schizophrenia and autism spectrum disorder by Bin Lu, Xue Li, Xue-Ping Gao, Jing Chen, Yi Liu, Jian-Ping Lu, Siu-Ching Kat, Zeng-Hui Ma, Li-Yang Zhao, Ting-Ni Yin, Xing Su, Fan-Chao Meng, Ya-Ru Zhang, Shu-Xian Wu, Wen-Jie Yan, Ya-Song Du, Xue-Rong Luo, Jing Liu, Chao-Gan Yan

    Published 2024-03-01
    “…The decreased network functional connectivity and compressed functional gradients in ASD are likely to contribute to reduced network efficiency. …”
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  13. 833
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  15. 835

    Effects of different exercise modalities on balance performance in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials by Shikun Zhang, Guoping Qian, Hong Xu, Meiling Gu, Sujie Mao, Yan’an Wang, Yuqing Zhang, Wensheng Zhou

    Published 2025-07-01
    “…Abstract Background Exercise has been proven to significantly enhance balance performance in healthy older adults, particularly those living independently in community settings. …”
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  16. 836

    Impacts of Chelated Iron Supplement with Organic Acid and Amino Acid on Growth Performance, Nutrient Digestibility, Feeding Behaviors, and Blood Parameters in Suckling Calves by Mahdi Ghavidel, Abdolhakim Toghdory, Taghi Ghoorchi, Mohammad Asadi

    Published 2024-10-01
    “…In the early stages of life, calves do not have a functional rumen, and it seems that they are more like monogastric animals that must obtain the nutrients they need. …”
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  17. 837

    Investigation of the performance of activated carbon derived from ripe plantain peels for CO2 capture: Modelling and optimisation using response surface methodology by Emmanuel Rieborue Khama, Emmanuel Zeneboebi Loyibo, Wilfred Okologume, Stanley Toochukwu Ekwueme, Chukwudi Victor Okafor, Nnaemeka Princewill Ohia

    Published 2024-06-01
    “…PPAC was prepared through carbonization and activation using H3PO4, and its unique properties were extensively characterized which revealed irregular sponge-like protrusions and well-defined pores under Scanning Electron Microscopy (SEM). …”
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  18. 838
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    Locus coeruleus co‐activation patterns at rest show higher state persistence in patients with dissociative seizures: A Pilot Study by Samantha Weber, Johannes Jungilligens, Selma Aybek, Stoyan Popkirov

    Published 2024-12-01
    “…Alterations in stress‐related endocrine function have been demonstrated, but the timescale of dissociation suggests that the central locus coeruleus (LC) noradrenergic system is likely pivotal. …”
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  20. 840

    Responsiveness of the mini-balance evaluation systems test, dynamic gait index, Berg balance scale, and performance-oriented mobility assessment in parkinson’s disease by Maryam Mehdizadeh, Seyed-Mohammad Fereshtehnejad, Merrill R. Landers, Parvaneh Taghavi Azar Sharabiani, Mohsen Shati, Seyede Salehe Mortazavi, Sayed Amir Hasan Habibi, Korosh Mansoori, Mahsa Meimandi, Zahra Nodehi, Zakieh Sadat Saberi, Ghorban Taghizadeh

    Published 2025-07-01
    “…Abstract Commonly used clinical tools like the Mini-Balance Evaluation Systems Test (Mini-BESTest), Dynamic Gait Index (DGI), Berg Balance Scale (BBS), and Performance-Oriented Mobility Assessment (POMA) are essential for assessing balance impairments in people with Parkinson’s disease (PwPD), but their clinical relevance depends on understanding the Minimal Important Difference (MID) and Minimal Detectable Change (MDC). …”
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