-
601
Rethinking Advanced Driver Assistance System taxonomies: A framework and inventory of real-world safety performance
Published 2025-01-01“…(−10.7%). However, systems like ACC! (ACC!) and CC! (CC!) were associated with increased crash rates (+8%, +12%). …”
Get full text
Article -
602
Wearable Solutions: Design, Durability, and Electrical Performance of Snap Connectors and Integrating Them into Textiles Using Interconnects
Published 2024-07-01“…Factors such as electrical functionality and mechanical durability along with textile compatibility are crucial for their performance. …”
Get full text
Article -
603
-
604
Long-term follow-up of “three horse shoe-like incision (3-HSI) holmium laser enucleation of the prostate: outcomes and efficacy of a novel en-bloc technique for anatomic transureth...
Published 2025-07-01“…Abstract Purpose This study aims to evaluate the long-term outcomes of the novel “three horseshoe-like incision” (3-HSI) technique for holmium laser enucleation of the prostate (HoLEP) compared to the traditional three-lobe HoLEP method in treating benign prostatic hyperplasia (BPH). …”
Get full text
Article -
605
Exploring the mechanism of triptolide inhibiting the motility of fibroblast-like synoviocytes in rheumatoid arthritis via RhoA/Rho-associated kinase axis, based on network pharmaco...
Published 2025-04-01“…Background and objectiveRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the hyperproliferation and invasive behavior of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS), which contributes to the degradation of articular cartilage and bone. …”
Get full text
Article -
606
Research on de-noising method of optical fiber grating sensing signal based on S-G and CEEMDAN technology
Published 2025-02-01Get full text
Article -
607
-
608
Clinical and Functional Characterization of Novel AGL Variants in Two Families with Glycogen Storage Disease Type III
Published 2023-01-01“…Based on the ACMG criteria, both variants were considered likely pathogenic, in accordance with the functional analysis results, which demonstrated that the mutated protein was still localized in the cytoplasm and that the glycogen content of cells transfected with the mutated AGL was increased compared to cells transfected with the wild-type one. …”
Get full text
Article -
609
Association of frailty with physical activity behaviour and well-being in older employees: moderated mediation by functional difficulty
Published 2025-01-01“…Conclusion Older employees with frailty are less likely to report lower functional difficulty and well-being at higher PAB. …”
Get full text
Article -
610
Ab initio density functional theory of Fe5Ni4S8 (022) and (400) surfaces
Published 2024-01-01“…In the present study we used density functional theory (DFT) to study compare stability of Fe5Ni4S8 (022) and (400) surfaces by investigating their structural and electronic properties. …”
Get full text
Article -
611
Anatomy and transcriptomics of the common jingle shell (Bivalvia, Anomiidae) support a sensory function for bivalve tentacles
Published 2024-12-01“…However, the genomic and phenotypic features that support sensory functions remain enigmatic for many invertebrates, such as bivalves, an ecologically and economically important taxonomic group. …”
Get full text
Article -
612
Genotype–phenotype analysis and functional study of three novel LRP6 variants in non-syndromic oligodontia
Published 2025-06-01“…Herein we aimed to identify novel LRP6 variants in patients with non-syndromic oligodontia (NSO) and perform functional analyses of these variants.Methods:Whole-exome sequencing (WES) was conducted on probands and their first-degree relatives to identify potential pathogenic variants. …”
Get full text
Article -
613
Role of obturator in restoring quality of life and function in maxillary oncological defect cases- A systematic review
Published 2024-09-01“…This positive impact is likely due to the prostheses' ability to restore oral and facial functions, improve speech, and enhance self-esteem and social interactions.…”
Get full text
Article -
614
A Comparison of Approaches for Segmenting the Reaching and Targeting Motion Primitives in Functional Upper Extremity Reaching Tasks
Published 2024-01-01“…There is growing interest in the kinematic analysis of human functional upper extremity movement (FUEM) for applications such as health monitoring and rehabilitation. …”
Get full text
Article -
615
Silent but significant: Functional elucidation of a synonymous ATP7B mutation in Wilson’s disease pedigrees
Published 2025-06-01“…Bioinformatics tools (HSF, SpliceAI and ESEfinder 3.0) were used to predict the impact of mutations on the splicing function of precursor mRNA. The in vitro minigene experiment was conducted to verify the impact of the mutation on the splicing function of the precursor mRNA.ResultsWhole-exome sequencing of the proband identified a synonymous variant c.2145C>T (p. …”
Get full text
Article -
616
Identification and functional characterization of ABCA4 gene variants in three patients with Stargardt disease or retinitis pigmentosa
Published 2025-06-01“…IntroductionThe diversity of phenotypes, ranging from inherited retinal dystrophies (such as Stargardt disease 1, cone–rod dystrophy 3, and retinitis pigmentosa 19) to late-onset age-related macular degeneration 2, has been attributed to loss-of-function variants in the ABCA4 gene. In this study, we aimed to identify and analyze potential pathogenic ABCA4 variants in patients with Stargardt disease or retinitis pigmentosa and to explore the impact of an intronic variant (NM_000350.3:c.6386 + 4A>G) on mRNA splicing.MethodsWe enrolled three patients from unrelated families with Stargardt disease or retinitis pigmentosa after comprehensive ophthalmological evaluations were performed. …”
Get full text
Article -
617
Selective dorsal rhizotomy long-term effects on functional motility in Jordanian children with spastic cerebral palsy
Published 2025-01-01“…These findings suggest that younger children (<10 years old) and more impaired (levels IV and V on GMFCS) are likely the best candidates for this procedure. Twelve-month functional improvement was similar in boys and girls (GMFCS decreased in 44.0% of boys vs. 37.5% of girls). …”
Get full text
Article -
618
Preoperative liraglutide modulates control of fat and glucose metabolism during cardiopulmonary bypass surgery
Published 2025-02-01“…Introduction: Glucagon-like peptide-1 receptor agonists reduce insulin requirements and improve glucose control when administered before cardiac surgery. …”
Get full text
Article -
619
Pathophysiological mechanisms of integrated regulation of water-sodium homeostasis: from cellular dysfunction of Na-K-ATPase to dysregulation of systemic volume control: a systemat...
Published 2025-08-01“…The cellular subsystem (digitalis-like compounds/Na-K-ATPase) is functionally integrated with the systemic subsystem (natriuretic peptides/neurohormonal regulation) to maintain homeostasis. …”
Get full text
Article -
620