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  1. 601

    Rethinking Advanced Driver Assistance System taxonomies: A framework and inventory of real-world safety performance by Ksander N de Winkel, Michiel Christoph

    Published 2025-01-01
    “…(−10.7%). However, systems like ACC! (ACC!) and CC! (CC!) were associated with increased crash rates (+8%, +12%). …”
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    Article
  2. 602

    Wearable Solutions: Design, Durability, and Electrical Performance of Snap Connectors and Integrating Them into Textiles Using Interconnects by Prateeti Ugale, Shourya Lingampally, James Dieffenderfer, Minyoung Suh

    Published 2024-07-01
    “…Factors such as electrical functionality and mechanical durability along with textile compatibility are crucial for their performance. …”
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    Article
  3. 603
  4. 604

    Long-term follow-up of “three horse shoe-like incision (3-HSI) holmium laser enucleation of the prostate: outcomes and efficacy of a novel en-bloc technique for anatomic transureth... by Maximilian Glienke, MF von Bargen, A Özkan, D Sirtl, C Gratzke, A Miernik, D Schoeb

    Published 2025-07-01
    “…Abstract Purpose This study aims to evaluate the long-term outcomes of the novel “three horseshoe-like incision” (3-HSI) technique for holmium laser enucleation of the prostate (HoLEP) compared to the traditional three-lobe HoLEP method in treating benign prostatic hyperplasia (BPH). …”
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    Article
  5. 605

    Exploring the mechanism of triptolide inhibiting the motility of fibroblast-like synoviocytes in rheumatoid arthritis via RhoA/Rho-associated kinase axis, based on network pharmaco... by Jiacheng Shen, Jiacheng Shen, Jiacheng Shen, Yuxuan Fang, Yuxuan Fang, Nan Xu, Nan Xu, Hongyi Chen, Hongyi Chen, Miao Zhu, Miao Zhu, Dan Li, Dan Li, Zewen Chu, Masataka Sunagawa, Yanqing Liu, Yanqing Liu, Haibo Wang, Haibo Wang, Guoqing Li, Guoqing Li

    Published 2025-04-01
    “…Background and objectiveRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the hyperproliferation and invasive behavior of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS), which contributes to the degradation of articular cartilage and bone. …”
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  6. 606
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  8. 608

    Clinical and Functional Characterization of Novel AGL Variants in Two Families with Glycogen Storage Disease Type III by Tingting Yu, Hao Fu, Aoyu Yang, Yan Liang

    Published 2023-01-01
    “…Based on the ACMG criteria, both variants were considered likely pathogenic, in accordance with the functional analysis results, which demonstrated that the mutated protein was still localized in the cytoplasm and that the glycogen content of cells transfected with the mutated AGL was increased compared to cells transfected with the wild-type one. …”
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    Article
  9. 609

    Association of frailty with physical activity behaviour and well-being in older employees: moderated mediation by functional difficulty by Emelia Danquah, Nestor Asiamah, Reginald Arthur-Mensah Jnr, Alex Sui Wing Chan, Hafiz T. A. Khan

    Published 2025-01-01
    “…Conclusion Older employees with frailty are less likely to report lower functional difficulty and well-being at higher PAB. …”
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    Article
  10. 610

    Ab initio density functional theory of Fe5Ni4S8 (022) and (400) surfaces by Molala Kgwajana, Mehlape Mofuti, Ngoepe Phuti, Mkhonto Prince

    Published 2024-01-01
    “…In the present study we used density functional theory (DFT) to study compare stability of Fe5Ni4S8 (022) and (400) surfaces by investigating their structural and electronic properties. …”
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    Article
  11. 611

    Anatomy and transcriptomics of the common jingle shell (Bivalvia, Anomiidae) support a sensory function for bivalve tentacles by Jorge A. Audino, Kyle E. McElroy, Jeanne M. Serb, José E. A. R. Marian

    Published 2024-12-01
    “…However, the genomic and phenotypic features that support sensory functions remain enigmatic for many invertebrates, such as bivalves, an ecologically and economically important taxonomic group. …”
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    Article
  12. 612

    Genotype–phenotype analysis and functional study of three novel LRP6 variants in non-syndromic oligodontia by Yunyun Yuan, Ya Zhao, Lingqiang Meng, Shuyun Zheng, Hui Li, Jiabao Ren, Beibei Li, Chenyun Dou, Yan Hou, Wenjing Chen, Jing Zhang, Jing Zhang, Yulin Ding, Yulin Ding, Wenjing Shen

    Published 2025-06-01
    “…Herein we aimed to identify novel LRP6 variants in patients with non-syndromic oligodontia (NSO) and perform functional analyses of these variants.Methods:Whole-exome sequencing (WES) was conducted on probands and their first-degree relatives to identify potential pathogenic variants. …”
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  13. 613

    Role of obturator in restoring quality of life and function in maxillary oncological defect cases- A systematic review by Neelima Manoj, Ahila Singaravel Chidambaranathan, MuthuKumar Balasubramanium, Ganesh RamKumar Rajapandi

    Published 2024-09-01
    “…This positive impact is likely due to the prostheses' ability to restore oral and facial functions, improve speech, and enhance self-esteem and social interactions.…”
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  14. 614

    A Comparison of Approaches for Segmenting the Reaching and Targeting Motion Primitives in Functional Upper Extremity Reaching Tasks by Kyle L. Jackson, Zoran Duric, Susannah M. Engdahl, Anthony C. Santago, Siddhartha Sikdar, Lynn H. Gerber

    Published 2024-01-01
    “…There is growing interest in the kinematic analysis of human functional upper extremity movement (FUEM) for applications such as health monitoring and rehabilitation. …”
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    Article
  15. 615

    Silent but significant: Functional elucidation of a synonymous ATP7B mutation in Wilson’s disease pedigrees by Qi Zhang, Qi Zhang, Xiaoming Xie, Hairong Li, Yulei Li, Hongyao Huang, Hongyao Huang

    Published 2025-06-01
    “…Bioinformatics tools (HSF, SpliceAI and ESEfinder 3.0) were used to predict the impact of mutations on the splicing function of precursor mRNA. The in vitro minigene experiment was conducted to verify the impact of the mutation on the splicing function of the precursor mRNA.ResultsWhole-exome sequencing of the proband identified a synonymous variant c.2145C>T (p. …”
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  16. 616

    Identification and functional characterization of ABCA4 gene variants in three patients with Stargardt disease or retinitis pigmentosa by Qi Luo, Juan Huang, Lu Shi, Lu Shi, Guanghong Zhang, Linping Xue, Kehu Wu, Xiaoyu Li, Lei Yang, Dujun Li, Liangwei Mao, Jihong Luo

    Published 2025-06-01
    “…IntroductionThe diversity of phenotypes, ranging from inherited retinal dystrophies (such as Stargardt disease 1, cone–rod dystrophy 3, and retinitis pigmentosa 19) to late-onset age-related macular degeneration 2, has been attributed to loss-of-function variants in the ABCA4 gene. In this study, we aimed to identify and analyze potential pathogenic ABCA4 variants in patients with Stargardt disease or retinitis pigmentosa and to explore the impact of an intronic variant (NM_000350.3:c.6386 + 4A>G) on mRNA splicing.MethodsWe enrolled three patients from unrelated families with Stargardt disease or retinitis pigmentosa after comprehensive ophthalmological evaluations were performed. …”
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  17. 617

    Selective dorsal rhizotomy long-term effects on functional motility in Jordanian children with spastic cerebral palsy by Yazan E. Al-kharabsheh, Anas Said, Ismail A. Ismaiel, Issam Khawaja, Marwan Altaher, Ali Bani-Ahmed, Carmen M. Cirstea, Carmen M. Cirstea

    Published 2025-01-01
    “…These findings suggest that younger children (<10 years old) and more impaired (levels IV and V on GMFCS) are likely the best candidates for this procedure. Twelve-month functional improvement was similar in boys and girls (GMFCS decreased in 44.0% of boys vs. 37.5% of girls). …”
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  18. 618

    Preoperative liraglutide modulates control of fat and glucose metabolism during cardiopulmonary bypass surgery by Robert van Wilpe, Abraham H Hulst, Steven E Thiessen, J Hans DeVries, Benedikt Preckel, Jeroen Hermanides

    Published 2025-02-01
    “…Introduction: Glucagon-like peptide-1 receptor agonists reduce insulin requirements and improve glucose control when administered before cardiac surgery. …”
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  19. 619

    Pathophysiological mechanisms of integrated regulation of water-sodium homeostasis: from cellular dysfunction of Na-K-ATPase to dysregulation of systemic volume control: a systemat... by Anatoliy Gozhenko, Walery Zukow, Olena Gozhenko, Mykhailo Saensus, Oleksandr Vitiukov

    Published 2025-08-01
    “…The cellular subsystem (digitalis-like compounds/Na-K-ATPase) is functionally integrated with the systemic subsystem (natriuretic peptides/neurohormonal regulation) to maintain homeostasis. …”
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  20. 620