Applying integrated transcriptome and single-cell sequencing analysis to develop a prognostic signature based on M2-like tumor-associated macrophages for breast cancer by Yanghaochen Xu, Peiyan Lin, Ye Zhu, Qing Zhang, Jinhong Zhou

“…Abstract Background M2-like tumor-associated macrophages (M2-like TAMs) function crucially in the tumor microenvironment (TME) and cancer development. …”
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Functional Enrichment Analysis of Rare Mutations in Patients with Brain Arteriovenous Malformations by Elena Zholdybayeva, Ayazhan Bekbayeva, Karashash Menlibayeva, Alua Gusmaulemova, Botakoz Kurentay, Bekbolat Tynysbekov, Almas Auganov, Ilyas Akhmetollayev, Chingiz Nurimanov

“…<b>Conclusions</b>: Defects in genes associated with ciliary structure and function may be critical to the pathogenesis of brain AVMs. …”
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The effect of propofol on the grading of diastolic function: a prospective observational study by Shalin Desai, Zachary Hamilton, Lynh McCloskey, Orode Badakhsh, David Li, Neal W. Fleming

“…Of those 49 patients, 20 (41%) had an improvement, while 29 (59%) had a worsening of their diastolic function grade. Patients with a lower e’ pre-induction value or a higher E/e’ pre-induction ratio were more likely to have an improved post-induction diastolic function grade. …”
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Therapeutic gene targets and epigenetic modifications in rheumatoid arthritis: Insights from MTX, JAK inhibitors, and LLDT-8 by Jianan Zhao, Yunshen Li, Runrun Zhang, Yu Shan, Chenyang Song, Yaxin Cheng, Yiming Shi, Yixin Zheng, Fuyu Zhao, Junyu Fan, Cen Chang, Yuejuan Zheng, Dongyi He

“…The intersection of differentially expressed genes with trend analysis identified as potential drug target genes. Functional enrichment analyses were performed to explore associated pathways. …”
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Swimming Exercise Pretreatment Attenuates Postoperative Delirium‐Like Behavior in Type 2 Diabetic Rats by Enhancing Mitochondrial Biogenesis Through Activation of SIRT2 Deacetylati... by Kaixi Liu, Lei Chen, Xinning Mi, Qian Wang, Yitong Li, Jingshu Hong, Xiaoxiao Wang, Yue Li, Yanan Song, Yi Yuan, Jie Wang, Dengyang Han, Taotao Liu, Ning Yang, Xiangyang Guo, Zhengqian Li

“…Preoperative swimming exercise was beneficial in attenuating delirium‐like behavior, inhibiting neuroinflammation, and improving mitochondrial biogenesis and function. …”
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Apoptosis-Associated Speck-Like Protein Containing a CARD Deletion Ameliorates Unilateral Ureteral Obstruction Induced Renal Fibrosis and Endoplasmic Reticulum Stress in Mice by Yao Xu, Yuqing Liu, Honglei Guo, Wei Ding

“…Inflammation might be one of the essential underlying mechanisms of renal fibrosis, which is considered a key pathological feature of end-stage renal disease and is closely associated with proteinuria and decreased renal function. Apoptosis-associated speck-like protein containing a CARD (ASC), identified as the central structure of inflammasome, is involved in the progression of interstitial fibrosis; however, its signal transduction pathways remain unclear. …”
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Expression of toll-like receptors and inflammatory mediators in primary human glioma cells (low- and high-grade) compared to primary cells from epileptic human brain by Negin Masoomabadi, Safieh Ebrahimi, Farshid Noorbakhsh, Alireza Tabibkhooei, Gisou Mohaddes, Saeed Sadigh-Eteghad, Maryam Khaleghi Ghadiri, Tahereh Ghadiri, Ali Gorji

“…Objective(s): Toll-like receptors (TLRs) have been implicated in the pathogenesis of glioma as principal regulators of inflammation and innate immune function. …”
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In silico engineering of fullerene-like Al12N12 nanostructured for the adsorption of PH3, NH3, and COCl2 industrial affili-ate gases by Ededet A. Eno, Eban L. Kechi, Favour A. Nduoma, Henry O. Edet

“…Our results indicate that adsorption energies for PBE0 functional are more negative than those of the M06-2X and ώB97XD functionals which reveals that PBE0 functional shows better performance in evaluation of such weak interactions. …”
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Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity by Valentina Salvi, Carolina Gaudenzi, Barbara Mariotti, Gaia Giongrandi, Silvia Alacqua, Veronica Gianello, Tiziana Schioppa, Laura Tiberio, Angela Ceribelli, Carlo Selmi, Paolo Bergese, Stefano Calza, Annalisa Del Prete, Silvano Sozzani, Flavia Bazzoni, Daniela Bosisio

“…We hypothesize that sEV-miRNA non-canonical function consisting of the stimulation of Toll-like receptor 7 (TLR7) may rely on a global shift of the sEV cargo rather than on the induction of one or few specific miRNAs. …”
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Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision by Glen Jeffery, Robert Fosbury, Edward Barrett, Chris Hogg, Marisa Rodriguez Carmona, Michael Barry Powner

“…Exposure to these longer wavelengths improves mitochondrial function and ATP production. This can translate to improved physiological performance, particularly in the CNS, including the visual system. …”
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EIN3/EIL (Ethylene Insensitive3 / Ethylene Insensitive3 Like) Protein Family in Phaseolus vulgaris: Identification, Evolution and Expression Analysis within the Genome by Simay Ezgi Akbulut, Zehra Şafak, Aybüke Okay, Kimia Amirina, Ilker Büyük

“…Ethylene insensitive-3 (EIN3) / Ethylene insensitive-3-like (EIL) protein family is a small family of transcription factors specific to plants that play role in plant growth and development under various environmental conditions. …”
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Multifunctional MOF-based Ag3PO4-enriched diamond-Like Cu-BTC composite membranes for enhanced selectivity, higher flux, and superior antifouling by Farah Abuhatab, Thanigaivelan Arumugham, Mariam Ouda, Shadi W. Hasan

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The clinical significance of insulin-like growth factor-1 and cystatin C in predicting the risk of developing complications of chemoresistant pulmonary tuberculosis in patients und... by O. M. Raznatovska, H. V. Khudiakov

“…In contemporaryUkraine, the urgency of pulmonary chemoresistant tuberculosis (CRTB) problem is evident as it is the cause of severe clinical condition, subjective and functional disorders causing disease-specific distress in patients. …”
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Why Is the Association Between Mediterranean Diet and Physical Performance in Athletes Inconclusive? Implications for Future Studies by Alain Massart, Ádrian Rocha, José Pedro Ferreira, Carmen Soares, Maria João Campos, Diogo Martinho

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Modified generalized Chen distribution, estimation and application using econometrics data by Owens Ogheneochuko Akpojaro, Charles Okechukwu Aronu

“…The objectives of the study was to derive the probability density function (PDF) and cumulative density function (CDF) of the MGC distribution, determine its statistical properties and reliability characteristics, compare these properties and characteristics to existing distributions, and empirically evaluate its performance. …”
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Nonlinear H∞ Optimal Control Scheme for an Underwater Vehicle with Regional Function Formulation by Zool H. Ismail, Matthew W. Dunnigan

“…A Lyapunov-like function is presented for stability analysis of the proposed control law. …”
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Advanced GIS-based Multi-Function Support System for Identifying the Best Route by Suhiar Mohammed Zeki Abd Alsammed

“…Furthermore, GIS provide multi-functions like data collection, analysis, and presentation. …”
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Shakespeare’s Secular Theatre: A Provocative Defence of the Actor and Spectator by Clotilde Thouret

“…A Midsummer Night’s Dream, As You Like It and Hamlet reproduce the theatrophobic accusations against actors and the contamination of the spectator by the passions performed on stage. …”
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Effect of polar functional groups on the hydrophobicity of carbon nanotubes-bacterial cellulose nanocomposite by Sa’aya Nurul Syahirah Nasuha, Halim Norhana Abdul, Norrrahim Mohd Nor Faiz, Tajuddin Hairul Anuar, Demon Siti Zulaikha Ngah, Azmi Ahmad Farid Mohd

“…Over the years, CNT-based sensors have offered exceptional conductivity and mechanical properties but have been hindered by humidity, affecting the performance of electrical measurements. Consequently, the aim of this study is to investigate the effect of various polar functional groups (e.g., –OH, –COOH, –F, and –NH2) on the wettability of CNT nanocomposites, employing bacterial cellulose (BC) as a binder. …”
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Functional connectivity and GABAergic signaling modulate the enhancement effect of neurostimulation on mathematical learning. by George Zacharopoulos, Masoumeh Dehghani, Beatrix Krause-Sorio, Jamie Near, Roi Cohen Kadosh

“…Effortful learning and practice are integral to academic attainment in areas like reading, language, and mathematics, shaping future career prospects, socioeconomic status, and health outcomes. …”
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