Hypoglycemic polysaccharides from Auricularia auricula and Auricularia polytricha inhibit oxidative stress, NF-κB signaling and proinflammatory cytokine production in streptozotoci... by Huan Xiang, Dongxiao Sun-Waterhouse, Chun Cui

“…APP and AAP with different molecular weights and monosaccharide molar ratios could be therapeutic options for diabetes with a low dose (100 mg/kg/day) likely working better. At the same dose, APP generally performed more effective than AAP, and AAP-10/APP-10 seemed slightly more beneficial than AAP/APP. …”
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Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis by Yingchao Fan, Liting Wu, Wenfang Zhuang

“…In addition, variations in MTHFR functions likely play roles in the etiology of EH. …”
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Conceptual Perspectives on State Fragility by D. P. Elagin

“…However, these approaches tend to view fragile states as a deviation from the Europe an nation-state model and focus more on the attributes of fragility (inability to perform core functions of the state or lacking the capacity to cope with risks and crises) while failing to produce a precise explanation for its causes. …”
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Alcohol consumption among persons living with hypertension: evidence from a population-based study in Cape Verde by Joshua Okyere, Castro Ayebeng, Kwamena Sekyi Dickson

“…Urban residents [AOR = 1.76; 95% CI: 1.33–2.31] and current smokers [AOR = 2.23; 95% CI: 1.13–4.38] were more likely to consume alcohol. Individuals with higher education [AOR = 4.34; 95% CI: 1.97–9.55] were more likely to consume alcohol but less likely to experience AUD [AOR = 0.09, 95%CI: 0.02–1.87]. …”
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Subtle myocardial effects of rheumatic heart disease in children are revealed earlier with two-dimensional speckle tracking echocardiography by Hüseyin Ilgın Bal, İrem Türkyılmaz, Şeyma Kayalı, Ayhan Kılıç

“…In the subclinical course of carditis, the absence of typical symptoms and the normal range of classical echocardiographic measurements used to evaluate cardiac functions have required new echocardiographic methods and parameters. …”
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Pressure-induced decomposition of β-SnWO4 by Sergio Ferrari, Daniel Diaz-Anichtchenko, Pablo Botella, Jordi Ibáñez, Robert Oliva, Alexei Kuzmin, Alfonso Muñoz, Frederico Alabarse, Daniel Errandonea

“…This result contradicts a previous study that, based on density-functional theory calculations and crystal-chemistry arguments, predicted a pressure-driven transition from β-SnWO4 to α-SnWO4. …”
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Development of a novel radioiodinated compound for amyloid and tau deposition imaging in Alzheimer's disease and tauopathy mouse models by Xiyan Rui, Xinran Zhao, Nailian Zhang, Yuzhou Ding, Chie Seki, Maiko Ono, Makoto Higuchi, Ming-Rong Zhang, Yong Chu, Ruonan Wei, Miaomiao Xu, Chao Cheng, Changjing Zuo, Yasuyuki Kimura, Ruiqing Ni, Mototora Kai, Mei Tian, Chunyan Yuan, Bin Ji

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Liver stage P. falciparum antigens highly targeted by CD4+ T cells in malaria-exposed Ugandan children. by Gonzalo R Acevedo, Sophie S Samiee, Mikias Ilala, Justine Levan, Meagan E Olive, Riana D Hunter, Mary Prahl, Raja Rajalingam, John Rek, Grant Dorsey, Margaret E Feeney

“…This knowledge gap has impeded mechanistic studies to identify the effector functions most critical for protection. We performed a bioinformatic analysis of gene expression datasets to identify plasmodial genes that are highly and selectively expressed during liver stage infection and predict epitopes within them likely to bind MHC-II molecules prevalent in Uganda. …”
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Eighteen-Year Follow-Up of Bone Sculpting Using the 3A-2B Biological Rule for Immediate and Late Implant Placement With Immediate Loading in Maxillary Fixed Prostheses: A Clinical... by Fernando Rojas-Vizcaya

“…Notably, interproximal contacts between the prostheses had opened, likely due to continued craniofacial growth and bone remodeling, although this did not affect the patient’s functionality. …”
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Intra-articular drug injections in the combination treatment of rheumatic diseases by Yu. A. Olyunin

“…Intra-articular hyaluronic acid is likely to be a more promising treatment for OA. It may also relieve pain considerably and improve joint functions. …”
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Unexpected DNA loss mediated by the DNA binding activity of ribonuclease A. by Federico Donà, Jonathan Houseley

“…This effect will impact DNA recovery from multiple procedures and is likely to represent a source of sequence bias in genome-wide studies. …”
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Catalytic Effect of Ni and Cu Embedded Graphene Surface on SO2 Decomposition Reaction by Aykan Akça

“…SO2 decomposition reaction on Ni and Cu embedded graphene surfaces were investigated using density functional theory. Grime D2 correction was used for Van der Waals interactions that could be induced by the interactions between adsorbed structures and surface. …”
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Understanding early HIV-1 rebound dynamics following antiretroviral therapy interruption: The importance of effector cell expansion. by Tin Phan, Jessica M Conway, Nicole Pagane, Jasmine Kreig, Narmada Sambaturu, Sarafa Iyaniwura, Jonathan Z Li, Ruy M Ribeiro, Ruian Ke, Alan S Perelson

“…Understanding the factors that determine whether viral rebound is likely after treatment interruption can enable the development of optimal treatment regimens and therapeutic interventions to potentially achieve a functional cure for HIV-1. …”
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Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review by Joy Duxbury, Alina Haines-Delmont, John Baker, Peter Baker, Gary Bourlet, Elaine Craig, James Ridley, Rachel Whyte, Beth Morrison, Michaela Thomson, Anthony Tsang, Tella Lantta

“…The search covered evidence from 1 January 2001 up to 21 July 2021 and yielded 16,775 hits, which were then reduced to 14,383, after using EndNote X9’s (2013) inbuilt duplication detection function and manual de-duplication. Results were imported to Covidence. …”
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Subthalamic nucleus deep brain stimulation for cranial-cervical dystonia: optimal stimulation sites and networks by Hutao Xie, Jiansong Huang, Ningfei Li, Houyou Fan, Shihang Yang, Zixiao Yin, Zhaoting Zheng, Zehua Zhao, Yin Jiang, Lin Shi, Anchao Yang, Fangang Meng, Guanyu Zhu, Quan Zhang, Jianguo Zhang

“…Pre- and postoperative imaging was used to reconstruct electrode locations and model patient-specific electric fields. We then performed (i) voxel-wise sweet spot mapping to identify optimal stimulation sites, (ii) fiber filtering using normative tractography to determine white matter pathways associated with clinical improvement, and (iii) network mapping based on resting-state fMRI to identify functional connectivity patterns predictive of DBS response. …”
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MANUAL COLON-ANAL OR MECHANICAL COLORECTAL ANASTOMOSIS? COMPARATIVE ANALYSIS OF LAPAROSCOPIC LOW RESECTIONS OF THE RECTUM by I. L. Chernikovsky

“…Ultra-low anterior resections of the rectum are functionally preferred. When performing ISR, the technique of reservoir colo-anal anastomosis with preservation of the portion of the internal sphincter provides functional results comparable with those obtained using LAR.…”
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The Angiostrongylus vasorum Excretory/Secretory and Surface Proteome Contains Putative Modulators of the Host Coagulation by Nina Germitsch, Nina Germitsch, Tobias Kockmann, Lars M. Asmis, Lucienne Tritten, Manuela Schnyder

“…Proteins were quantified by liquid chromatography coupled to mass spectrometry and functionally characterized through gene ontology and pathway enrichment analysis. …”
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Legitimacy and Reflexivity in International Investment Arbitration: A New Self-Restraint? by David Schneiderman

“…In order to take stock of the degree of reflexivity, the paper examines the direction investment law is taking in a few key areas: first, in the shift in emphasis away from expropriations (the ‘takings rule’) to the fair and equitable treatment standard, which is performing similar functions; second, in the attempt to merge global standards by embracing World Trade Organization Appellate Body decision making; and third, the hesitant embrace of proportionality doctrine as a means of weighing public interests into the equation. …”
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Artificial Empathy in Home Service Agents: A Conceptual Framework and Typology of Empathic Human–Agent Interactions by Joohyun Lee, Hyo-Jin Kang

“…As artificial intelligence (AI) technology advances, there has been a diversification of home service functions and services, as well as a change in the applied technologies and functions. …”
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Health disparities and treatment approaches in portopulmonary hypertension and idiopathic pulmonary arterial hypertension: an analysis of the Pulmonary Hypertension Association Reg... by Hilary M. DuBrock, Charles D. Burger, Sonja D. Bartolome, Jeremy P. Feldman, D. Dunbar Ivy, Erika B. Rosenzweig, Jeffrey S. Sager, Kenneth W. Presberg, Stephen C. Mathai, Matthew R. Lammi, James R. Klinger, Michael Eggert, Teresa De Marco, Jean M. Elwing, David Badesch, Todd M. Bull, Linda M. Cadaret, Gautam Ramani, Thenappan Thenappan, H. James Ford, Nadine Al‐Naamani, Marc A. Simon, Sula Mazimba, James R. Runo, Murali Chakinala, Evelyn M. Horn, John J. Ryan, Robert P. Frantz, Michael J. Krowka, PHAR Investigators

“…Compared with IPAH, patients with POPH were less likely to be college graduates (19.6% vs. 34.9%, p = 0.02) and more likely to be unemployed (54.7% vs. 30.5%, p < 0.001) and have an annual household income below poverty level (45.7% vs. 19.0%, p < 0.001). …”
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