Mesenchymal stem cells derived from hPSC via neural crest attenuate chemotherapy-induced premature ovarian insufficiency by ameliorating apoptosis and oxidative stress in granulosa... by Xinran Li, Jinrong Liao, Youhong Zheng, Wei Cai, Jie Chen, Yu Liang, Yuanmei Chen, Xiaoxuan Li, Jiamao Luo, Jiaxin Xie, Manping Zhou, Lilin Hang, Xiujuan Sun, Xin Yue, Xuefeng Wang, Yifeng Wang, Huiyan Wang

“…The underlying mechanisms are likely associated with paracrine-mediated effects on GC apoptosis, oxidative stress, and mitochondrial dysfunction.…”
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Study of head and neck squamous cell carcinoma transcriptome after proton therapy by E. D. Jumaniyazova, P. A. Vishnyakova, M. V. Chirkova, E. A. Karpulevich, I. Z. Eremina, K. B. Gordon, A. D. Kaprin, T. H. Fatkhudinov

“…The predominance of suppressed signaling pathways over activated ones most likely indicates a decrease in the functional potential of cells after proton therapy. …”
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Aldo-keto Reductase 1B10 (AKR1B10) Suppresses Sensitivity of Ferroptosis in TNBC by Activating the AKT/GSK3β/Nrf2/GPX4 Axis by Shanli Wu, Gun Yang, Xiaosha Wen, Yi Lin, Shenglong Wang, Jing Wang, Quan Liu, Dixian Luo

“…Several studies have highlighted the essential function of AKR1B10 in lipid metabolism and in the detoxification of lipid peroxides. …”
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Activity and mechanism of naringin in the treatment of post-infectious cough by Yinghan Chen, Dong Wang, Meng Song, Weiqi Pan, Wenda Guan, Zifeng Yang, Shan Zhong

“…GO (Gene Ontology) functional annotation and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway enrichment analyses were performed with Metascape. …”
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Lazarettos , Tebhırhane and Tahaffuzhane Buıldıngs by Fatma Sedes

“…Religious hospitals, which were opened in Istanbul and functioned as shelters, have become modern hospitals in historical development. …”
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A Robust Cross-Platform Solution With the Sense2Quit System to Enhance Smoking Gesture Recognition: Model Development and Validation Study by Anarghya Das, Juntao Feng, Maeve Brin, Patricia Cioe, Rebecca Schnall, Ming-Chun Huang, Wenyao Xu

“… BackgroundSmoking is a leading cause of preventable death, and people with HIV have higher smoking rates and are more likely to experience smoking-related health issues. …”
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Mental fatigue of operating room nurses and its relationship with missed perioperative nursing care: a descriptive-analytical study by Vahid Rahmani, Valerie L. Marsh, Ebrahim Aliafsari Mamaghani, Ali Soleimani, Maedeh Alizadeh, Omid Zadi, Nasrin Aghazadeh

“…Abstract Introduction Mental fatigue is a psychological condition characterised by diminished alertness, impaired cognitive functioning, heightened error rates, and overall decreased performance. missed perioperative nursing care diminishes patient safety and increases the likelihood of adverse incidents. …”
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Deletion of p18INK4c enhances both osteogenesis and hematopoietic supportive capacity of bone marrow mesenchymal stromal cells by Wen Xing, Fang Dong, Yining Liu, Jiajia Yuan, Chao Chen, Yihan Li, Han Wang, Ming Yao, Ting Chen, Tao Cheng, Sha Hao, Yuan Zhou

“…Conclusions p18 deficiency promotes osteogenic differentiation and enhances the hematopoietic supportive function of MSCs, likely mediated by Opn upregulation. …”
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Impairment in work and activities of daily life in patients with psoriasis: results of the prospective BioCAPTURE registry by Tamara W. van Hal, Juul M. P. A. van den Reek, Mark H. Wenink, Marisol E. Otero, Paul M. Ossenkoppele, Marcellus D. Njoo, Annet Oostveen, Bas Peters, Milan Tjioe, Else N. Kop, John E. M. Körver, Sharon R. P. Dodemont, Marloes M. Kleinpenning, Maartje A. M. Berends, Wendelien R. Veldkamp, Martijn B. A. van Doorn, Johannes M. Mommers, Robert-Jan Lindhout, Astrid L. A. Kuijpers, Paula P. van Lümig, C. (Els) J. de Jonge, Ron A. Tupker, Judith Hendricksen, Romy R. Keijsers, Frank H. J. van den Hoogen, Johanna E. Vriezekolk, Elke M. G. J. de Jong

“…Associations between impairments and contextual factors varied, but all impairments were associated with worse mental/physical general functioning.Conclusion: Patients with psoriasis using biologicals are less likely to have work-for-pay. …”
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Expression and Localization of hspa5 in Response to Thermal Stress in the Spotted Sea Bass (Lateolabrax maculatus) by Xiaoqiang LIU, Chunhui FENG, Haishen WEN, Yun LI, Tianyu JIANG, Xin QI

“…HE staining revealed characteristic liver tissue morphology, including distinct features (e.g., the central vein and hepatocytes), under both normal and high-temperature conditions.These findings suggest that hepatocytes are likely the primary cell type that responds to high-temperature stress and serves a protective function. …”
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Variants in WASHC3, a component of the WASH complex, cause short stature, variable neurodevelopmental abnormalities, and distinctive facial dysmorphism by Youn Hee Jee, Julian C. Lui, Dana Marafi, Zhi-Jie Xia, Ruchika Bhatia, Elaine Zhou, Isabella Herman, Adrian Temnycky, Philip Whalen, Gene Elliot, Ellen W. Leschek, Robin Wijngaard, Ronald van Beek, Annemarie de Vreugd, Maaike C. de Vries, Clara D.M. van Karnebeek, Machteld M. Oud, Thomas C. Markello, Kevin M. Barnes, Hadil Alrohaif, Hudson H. Freeze, William A. Gahl, May Christine V. Malicdan, Jennifer E. Posey, James R. Lupski, Jeffrey Baron

“…Method: Exome sequence was performed in 3 unrelated families with short stature, distinctive facies, and neurodevelopmental abnormalities. …”
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A patient-derived HCC spheroid system to model the tumor microenvironment and treatment response by Emilie Crouchet, Nuno Almeida, Sarah C. Durand, Marie Parnot, Marine A. Oudot, Fabio Giannone, Cloé Gadenne, Natascha Roehlen, Antonio Saviano, Emanuele Felli, Patrick Pessaux, Hong Tuan Duong, Hideki Ohdan, Hiroshi Aikata, Kazuaki Chayama, Thomas F. Baumert, Catherine Schuster

“…Characterization of the tumor spheroid cell populations was performed by flow cytometry, immunohistochemistry (IHC), and functional assays. …”
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A multicenter validation and calibration of automated software package for detecting anterior circulation large vessel occlusion on CT angiography by Kyu Sun Yum, Jong-Won Chung, Sue Young Ha, Kwang-Yeol Park, Dong-Ick Shin, Hong-Kyun Park, Yong-Jin Cho, Keun-Sik Hong, Jae Guk Kim, Soo Joo Lee, Joon-Tae Kim, Woo-Keun Seo, Oh Young Bang, Gyeong-Moon Kim, Myungjae Lee, Dongmin Kim, Leonard Sunwoo, Hee-Joon Bae, Wi-Sun Ryu, Beom Joon Kim

“…The category of LVO probabilities was associated with follow-up infarct volumes and functional outcome. Conclusion In this multicenter study, we proved the clinical efficacy of the software in detecting LVO on CTA.…”
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Surgeons are apprehensive to use DCD lungs despite similar post-transplant outcomes: A 20-year UNOS retrospective analysis by J. Sam Meyer, MSc, Oliver K. Jawitz, MD, MHS, Yury Peysakhovich, MD, Dan Aravot, MD, Matthew G. Hartwig, MD, MHS, Yaron D. Barac, MD, PhD

“…DBD lungs consistently improved [95% 1.46–2.57, p < 0.001].Rejected DCD lungs were associated with donors with higher cardiopulmonary function. Left ventricular ejection fractions in discarded DCD lung donors were higher than those of discarded DBD lung donors (DCD 56.9% ± 13.6 vs. …”
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Sources of uncertainty in DNA metabarcoding of whole communities: Implications for its use in biomonitoring by J. Iwan Jones, Amanda Arnold, Dominik Buchner, John F. Murphy, Jasmine N. Childress, Pedro Beja, Florian Altermatt, Kristian Meissner, Ian Adams, Meri Anderson, Yaisel J. Borrell, Andrew G. Briscoe, Kat Bruce, Cátia Chaves, Chris Conyers, Kristy Deiner, Vasco Elbrecht, Álvaro Fueyo, Tim Goodall, Javier Granero‐Castro, Cristina Hartmann‐Fatu, Eleanor Jones, Elvira Mächler, Filipa M. S. Martins, Sam McGreig, Lyndall Pereira‐da‐Conceicoa, James L. Pretty, Daniel S. Read, Ben Price, Florian Leese, Rosetta C. Blackman

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CHANGES IN MORPHODENSITOMETRIC PARAMETERS OF THE PARAVENTRICULAR NUCLEUS OF THE HYPOTHALAMUS IN RATS UNDER STRESS OF DIFFERENT DURATIONS by І. Федоряк, Р. Булик

“…Light deprivation induces a disruption in the rhythm of functional activity of the studied hypothalamic neurons and a shift of peak values from the daytime to the nighttime period, likely attributable to increased levels of melatonin, the primary pineal chronobiotic, in the bloodstream during this phase of the day. …”
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Timing and Modality of Kidney Replacement Therapy in Children and Adolescents by Julia Thumfart, Steffen Wagner, Marietta Kirchner, Karolis Azukaitis, Aysun K. Bayazit, Lukasz Obrycki, Nur Canpolat, Ipek Kaplan Bulut, Ali Duzova, Ali Anarat, Lucie Bessenay, Rukshana Shroff, Dusan Paripovic, Lale Sever, Cengiz Candan, Francesca Lugani, Alev Yilmaz, Fatos Yalcinkaya, Klaus Arbeiter, Aysel Kiyak, Aleksandra Zurowska, Matthias Galiano, Uwe Querfeld, Anette Melk, Franz Schaefer, G. Cortina, K. Arbeiter, J. Dusek, J. Harambat, B. Ranchin, M. Fischbach, U. Querfeld, S. Habbig, M. Galiano, R. Büscher, C. Gimpel, M. Kemper, A. Melk, D. Thurn, F. Schaefer, A. Doyon, E. Wühl, M. Pohl, S. Wygoda, N. Jeck, B. Kranz, M. Wigger, G. Montini, F. Lugani, S. Testa, E. Vidal, C. Matteucci, S. Picca, A. Jankauskiene, K. Azukaitis, A. Zurowska, D. Drodz, M. Tkaczyk, T. Urasinski, M. Litwin, M. Szczepanska, A. Texeira, A. Peco-Antic, B. Bucher, G. Laube, A. Anarat, A.K. Bayazit, F. Yalcinkaya, E. Basin, N. Cakar, O. Soylemezoglu, A. Duzova, Y. Bilginer, H. Erdogan, O. Donmez, A. Balat, A. Kiyak, S. Caliskan, N. Canpolat, C. Candan, M. Civilibal, S. Emre, G. Ozcelik, S. Mir, B. Sözeri, O. Yavascan, Y. Tabel, P. Ertan, E. Yilmaz, R. Shroff

“…Patients with glomerulopathies were more likely to start dialysis than children with congenital anomalies of the kidneys and urinary tracts (CAKUT) (HR: 3.81 [2.52–5.76]). …”
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Explaining the Comprehensive Human-To-Human Marketig System in the Health Tourism Industry by Ali Pourang, Meysam Shirkhodaie, Mahmood Yahyazadeh far, Mohsen Alizadeh San, Masoomeh Tavangar

“…Ethical Inquiries: Address issues like organ transplant tourism (Budiani-Saberi & Delmonico, 2008). …”
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STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma by Dingheng Lu, Yuxiao Li, Xinyang Niu, Jiazhu Sun, Weitao Zhan, Yuchen Shi, Kai Yu, Suyuelin Huang, Xiaoyan Liu, Liping Xie, Xueyou Ma, Ben Liu

“…Solute carrier family 27 member 3 (SLC27A3), highly expressed in lipid-rich tumors like ccRCC, has been associated with poor prognosis. …”
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Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway by Qiuhong Jiao, Xiufeng Xu, Longwu Xu, Yuying Wang, Shulan Pang, Jie Hao, Xiaohong Liu, Yudan Zhao, Wanpeng Qi, Limin Qin, Tao Huang, Jingtian Li, Tao Wang

“…Double-labeled immunofluorescence showed eIF3a was mostly co-localized with CD31, this result indicated that the development of MCT-induced PAH was related to the regulation of PAECs function (most likely associated with the change of EndMT in endothelial cells). …”
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