Deep analysis of the major histocompatibility complex genetic associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Cont... by Myriam Rahmouni, Sigrid Le Clerc, Jean-Louis Spadoni, Taoufik Labib, Maxime Tison, Raissa Medina-Santos, Armand Bensussan, Ryad Tamouza, Jean-François Deleuze, Jean-François Zagury

“…Conclusion Our results show that MHC influence on EC likely extends beyond traditional HLA class I or class II allele associations, encompassing other MHC SNPs with various biological impacts. …”
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α-Klotho: An Early Risk-Predictive Biomarker for Acute Kidney Injury in Patients with Acute Myocardial Infarction by Yuanyuan Pei, Miao Miu, Xue Mao, Wen Chen, Jihong Zhu

“…And, patients with α-Klotho ≥516.9 pg/ml was 6.699 times more likely to develop CKD than those with α-Klotho <516.9 pg/ml (relative risk 6.699, 95% CI 1.631–27.519, p=0.007). …”
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Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave by Rafael Bielza, Patricia Pérez, Nuria García, Laura Ballesteros-Sanabria, Rosa María Martínez, Azam Ghazi, Clara Hernando, María Victoria Rodríguez, Israel J. Thuissard, Cristina Andreu-Vázquez, José Manuel Bautista

“…Abstract Background The function of mucosal secretory IgA (SIgA) seems to be paramount in the immune response against SARS-CoV-2 however, there are few studies addressing this issue specifically in the institutionalized older population. …”
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The effects of various nutritional supplements in patients with chronic obstructive pulmonary disease: a network meta-analysis by Jia Zeng, Jing Cheng, Liangdong Zhu, Sufang Tang

“…Specifically, Nanocurcumin may be the best choice for improving lung function; coenzyme Q10 combined with creatine may be the most effective for enhancing exercise endurance; Additionally, Yam-Epimedium is the most likely supplement to reduce the symptoms of dyspnea in COPD patients. …”
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Longitudinal characterization of the muscle metabolome in dairy cows during the transition from lactation cessation to lactation resumption by H. Sadri, M.H. Ghaffari, H. Sauerwein, S. Schuchardt, J. Martín-Tereso, John Doelman, J.B. Daniel

“…The metabolites produced by the l-Arg pathway might contribute to regulating skeletal muscle mass and function in periparturient dairy cows. The elevated concentrations of long-chain acylcarnitine species in the muscle in the first week after calving suggest incomplete fatty acid oxidation, likely due to insufficient metabolic adaptation in response to the fatty acid load around the time of calving.…”
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Oxidative Stress and Semen Quality Among Night- and Day-Shift Workers: A Cross-Sectional Study by Luca Boeri, Federica Passarelli, Ludovico Maria Basadonna, Edoardo Sorba, Giorgio Graps, Fabio Ciamarra, Damiano Dagnino, Valentina Parolin, Marco Nizzardo, Gianpaolo Lucignani, Emanuele Montanari

“…Statistical comparisons were performed using non-parametric tests and logistic regression analyses. …”
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Clinicopathological and genetic analysis of orbital solitary fibrous tumors by Qing Wang, Zonghan Nan, Xun Liu, Limin Zhu, Emmanuel Eric Pazo, Tianming Jian, Liang Zhao, Jinzhi Zhao, Tingting Lin

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Integrated transcriptomic and proteomic analysis identified key folate biosynthesis gene in waxy maize by Yanyan Jiao, Yaxing Shi, Hui Dong, Yujing Pan, Hui Liu, Zhiyong Li, Xiaqing Wang, Chunhui Li, Tianyi Wang, Shuai Wang, Ronghuan Wang, Baishan Lu, Wei Song, Jiuran Zhao

“…These genes encode enzymes that potentially function in folate biosynthesis. Functional validation of one of these genes, ZmADCL2, using an EMS mutant (Mut9264) showed that a 4-base insertion in an exon increased the folate content of fresh maize kernels 1.37-fold that of the wild type. …”
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Repurposing FDA-Approved Agents to Develop a Prototype <i>Helicobacter pylori</i> Shikimate Kinase (HPSK) Inhibitor: A Computational Approach Using Virtual Screening, MM-GBSA Calcu... by Abdulaziz H. Al Khzem, Tagyedeen H. Shoaib, Rua M. Mukhtar, Mansour S. Alturki, Mohamed S. Gomaa, Dania Hussein, Nada Tawfeeq, Mohsina Bano, Mohammad Sarafroz, Raghad Alzahrani, Hanin Alghamdi, Thankhoe A. Rants’o

“…MM-GBSA calculations were performed on these top candidates and the reference ligand to refine the analysis and compounds’ prioritization. …”
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Association of post-stroke hemiplegic shoulder pain with sleep quality, mood, and quality of life by Marzieh Khatooni, Leila Dehghankar, Fatemeh Samiei Siboni, Mahdieh Bahrami, Mahya Shafaei, Rahman Panahi, Mohamad Amerzadeh

“…These factors lead to poorer functional outcomes, reduced hand function, and difficulties in performing daily activities. …”
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Circ‐myh8/KAT7 Affects PANoptosis in Pulmonary Arterial Smooth Muscle Cells: Involvement of Super‐Enhancers in FOSL2 Expression by Jingya Zhang, Xinru Wang, Xu Wang, Songyue Li, Jianli Hou, Yibin Zhang, Xinyue Song, Shukun Cao, Ya Xu, Jing Qi, Baoshan Zhao, Xiaodong Zheng, Yan Xing

“…Results A combination of ChIP sequencing and RNA sequencing analyses confirmed that FOSL2 (Fos‐like antigen 2) is a target gene regulated by SEs. …”
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INTERRELATION OF TEMPOROMANDIBULAR JOINT DYSFUNCTION IN PATIENTS WITH GYNECOLOGICAL CHANGES IN ANAMNESIS ACCORDING TO THE QUESTIONNAIRE SURVEY by V.M. Novykov, A.I. Shvets, K.Y. Rezvina, M.A. Korostashova

“…Much attention is drawn to the study of estrogen, which, in addition to regulating the functioning of the reproductive system in a woman's body, also performs a number of other important functions, including helping the joint to remain healthy - preventing calcium leaching, stimulating collagen recovery and the work of osteoblasts. …”
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The use of modern military technologies in the light of the law of weapons and the law of targeting by Behzad Seyfi

“…Although new weapons, like any other emerging phenomenon have created legal challenges for manufacturers and tension between countries, but these tensions can be reduced by setting special regulations. …”
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Intracellular HIV-1 Tat regulator induces epigenetic changes in the DNA methylation landscape by Andrea Rodríguez-Agustín, Andrea Rodríguez-Agustín, Rubén Ayala-Suárez, Francisco Díez-Fuertes, Francisco Díez-Fuertes, María José Maleno, Izar de Villasante, Angelika Merkel, Mayte Coiras, Mayte Coiras, Víctor Casanova, Víctor Casanova, José Alcamí, José Alcamí, José Alcamí, José Alcamí, Núria Climent, Núria Climent, Núria Climent

“…IntroductionThe HIV regulatory protein Tat enhances viral transcription and also modifies host gene expression, affecting cell functions like cell cycle and apoptosis. Residual expression of Tat protein is detected in blood and other tissues even under antiretroviral treatment. …”
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A lightweight triple-modal fusion network for progressive mild cognitive impairment prediction in Alzheimer's disease by Xiangyu Shen, Xiangyang Hu, Renfeng Zhang, Yunzhan Fu, Jiamin Xu, Degang Lyu, Hongbiao Xie, Hongbiao Xie, Deen Shi, Changsheng Shi, Lisi Li, Yuantong Gao

“…Early identification of individuals with mild cognitive impairment (MCI) who are likely to convert to AD is essential for timely diagnosis and therapeutic intervention. …”
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From Development to Regeneration: Insights into Flight Muscle Adaptations from Bat Muscle Cell Lines by Fengyan Deng, Valentina Peña, Pedro Morales-Sosa, Andrea Bernal-Rivera, Bowen Yang, Shengping Huang, Sonia Ghosh, Maria Katt, Luciana Andrea Castellano, Lucinda Maddera, Zulin Yu, Nicolas Rohner, Chongbei Zhao, Jasmin Camacho

“…These cells exhibit frequent spontaneous contractions, suggesting robust functional integrity at the neuromuscular junction. …”
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中學生成長型思維與學習投入之關係： 以後設認知與羞愧感為中介變項 A Study on the Impact of Growth Mindset on Learning Engagement Among Junior and Senior High School Students: Exploring the Mediating Roles of Metac... by 王佳琪 Chia-Chi Wang, 孫國瑋 Guo-Wei Sun

“…For instrument reliability and validity, the analysis primarily involved the use of the Multidimensional Item Response Model (MPCM) to assess model-data fit, Differential Item Functioning (DIF), and respondent separation reliability. …”
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Multidisciplinary, multicenter consensus for the care of patients affected with Sturge–Weber syndrome by May El Hachem, Andrea Diociaiuti, Angela Galeotti, Francesca Grussu, Elena Gusson, Alessandro Ferretti, Carlo Efisio Marras, Davide Vecchio, Simona Cappelletti, Mariasavina Severino, Carlo Gandolfo, Simone Reali, Rosa Longo, Carmen D’Amore, Lodovica Gariazzo, Federica Marraffa, Marta Luisa Ciofi Degli Atti, Maria Margherita Mancardi, and the Sturge-Weber Syndrome Multidisciplinary Group

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Mandibular reconstruction outcomes for in-house patient-specific solutions by Matthew D. Marquardt, Erin Cowen, Rachel Fenberg, Natalia von Windheim, Margaret Lashutka, Abigail E. Reid, Amit Agarwal, Enver K. Ozer, Ricardo L. Carrau, James W. Rocco, Catherine T. Haring, Stephen Y. Kang, Nolan B. Seim, Matthew O. Old, Kyle K. VanKoevering

“…The advent of computer-aided design and manufacturing (CAD/CAM) has enhanced aesthetic and functional outcomes in mandibular reconstruction by enabling patient-specific solutions like 3D-printed anatomic models. …”
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Model for predicting risk of developing drug-induced liver injury during remdesivir therapy: observational prospective open case-control study by Yu. V. Shevchuk, A. V. Kryukov, I. I. Temirbulatov, I. V. Sychev, K. B. Mirzaev, N. P. Denisenko, Sh. P. Abdullaev, S. N. Tuchkova, V. I. Vechorko, O. V. Averkov, D. A. Sychev

“…According to a number of studies, the incidence of adverse reactions during remdesivir therapy reaches 66%, with the most common is an increase in liver function tests.The aim of the work was to study the influence of clinical, demographic and pharmacogenetic factors on the development of drug-induced liver damage during remdesivir therapy in COVID-19 patients.Materials and methods. …”
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