Early life origins cognitive decline: findings in elderly men in the Helsinki Birth Cohort Study. by Katri Raikkonen, Eero Kajantie, Anu-Katriina Pesonen, Kati Heinonen, Hanna Alastalo, Jukka T Leskinen, Kai Nyman, Markus Henriksson, Jari Lahti, Marius Lahti, Riikka Pyhälä, Soile Tuovinen, Clive Osmond, David J P Barker, Johan G Eriksson

“…Men who were born larger were more likely to perform better in the cognitive ability test over time (1.22-1.43 increase in odds to remain in the top relative to the lower two thirds in ability over time per each SD increase in body size, 95%CI:1.04 to 1.79) and were more resilient to cognitive decline after 20.1 years (0.69 to 0.76 decrease in odds to decline from than remain in the top third of ability over time per each SD increase in body size, 95%CI:0.49 to 0.99). …”
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Outcomes of Kidney Transplantation From Donors on Renal Replacement Therapy by Naeem Goussous, MD, Karima Alghannam, BS, Peter A. Than, MD, Aileen X. Wang, MD, Ling-Xin Chen, MD, Sophoclis P. Alexopoulos, MD, Junichiro Sageshima, MD, Richard V. Perez, MD

“…Donors in the AKI-RRT group were younger (28 versus 40), had less incidence of hypertension (15.3% versus 31.9%), and were more likely to be imported (94.9% versus 76.8%). There was a higher incidence of delayed graft function (72% versus 44%, P < 0.001) in the AKI-RRT group. …”
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Characterizing the gut microbiome of birds-of-paradise in the northwest lowland of Papua Island by Safika Safika, Agustin Indrawati, Rahmat Hidayat, Alif Rahman Rohim Puarada

“…Shotgun metagenomic sequencing was performed on the MGI DNBSEQ-G400 platform to obtain DNA sequences. …”
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SVseq discloses the genomic complexity of different prenatal, de novo, apparently balanced chromosome rearrangements detected by CMA and karyotype by Shengfang Qin, Xueyan Wang, Chun Chen, Jin Wang, Zhuo Zhang, Yan Yin, Xiangyou Leng

“…Additionally, this case was analyzed using WGS (30X), excluding other pathogenic or likely pathogenic SNVs/Indels that could explain the patient's abnormal phenotype. …”
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Causes of Emergency Bleeding after Nonsurgical Periodontal Therapy in Adult Periodontitis Patients: A Retrospective Analysis by Fei Lu, Gang-Gang Qi, Wen Fang, Xin Zhang, Jing Zhou, Xue-Fen Yu, Xiao-Jun Li

“…Angular alveolar bone resorption was more likely to cause bleeding than horizontal resorption. …”
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Efficacy and harms associated with β-blockers for cardiotoxicity in cancer patients undergoing chemotherapy: a systematic review and meta-analysis by Jessica T. Li, Amanda M. Duddy, Michelle Cardona, Vinay Pasupuleti, Adrian V. Hernandez

“…Inverse variance random effect meta-analyses were performed, and we used GRADE methods to assess quality of evidence (QoE). …”
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A Case Control Study Examining the Patterns and Predictors of Referral to Cancer Rehabilitation at Canada's Largest Comprehensive Cancer Centre by Jennifer M. Jones, Rogih Andrawes, Michelle A. Weller, Adrienne Lam, Gilla K. Shapiro, Madeline Li, Danielle Rodin, Lisa Avery

“…Cancer rehabilitation can reduce functional limitations among cancer survivors and enhance their well‐being. …”
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Impact of tafluprost and tafluprost/timolol on the thickness of the retina in the macular area by N. I. Kurysheva, E. V. Polunina, D. D. Arzhukhanov, A. M. Tkhamadokova

“…The measurements were performed in the macular area using a spectral domain optical coherence tomography (SD-OCT) by means of the RtVue xR Avanti with the AngioVue OCT angiography function. …”
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Assessment of Potentially Nephrotoxic Drug Prescriptions in Chronic Kidney Disease Outpatients at a Hospital in Indonesia by Kusumawardani LA, Risni HW, Naurahhanan D, Syed Sulaiman SA

“…Logistic regression analysis was performed to examine the association between patient characteristics and the prescription of PND.Results: In total, 248 patients were evaluated. …”
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Epigenetic regulation of MED12: a key contributor to the leukemic chromatin landscape and transcriptional dysregulation by Arundhati Chavan, Cassidy Jones, Whit Lawrence, Samrat Roy Choudhury

“…Our findings suggest that TPRR hypermethylation may function noncanonically to support transcriptional activation, likely in cooperation with enhancer elements. …”
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The impact of operative level on patient-reported outcome measures following single-level posterior lumbar decompression for disc herniation by Jonathan Dalton, Robert J. Oris, Omar H. Tarawneh, Gregory R. Toci, Rajkishen Narayanan, Dominic Finan, Hannah Bash, Marco Goldberg, John J. Mangan, Barrett I. Woods, Mark F. Kurd, Ian David Kaye, Jose A. Canseco, Alan S. Hilibrand, Alexander R. Vaccaro, Gregory D. Schroeder, Christopher K. Kepler

“…These patients had similar 1-year scores in ODI, VAS leg, and MCS but performed worse at 1 year in VAS back (3.58 vs. 2.75, P = 0.016) and at 6 months in ODI (24.5 vs. 17.9, P = 0.005) and were less likely to achieve MCID in PCS (48.8% vs. 64.4%, P = 0.041). …”
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Serum vitamin C levels and their correlation with chronic kidney disease in adults: a nationwide study by Chunli Wang, Jili Zhao, Qiaoqiao Zhou, Jing Li

“…Appropriately increasing serum vitamin C levels may hold promise in protecting renal function, particularly among older individuals.…”
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542 The association between cell-free DNA and lung transplant survival by Rohan Meda, Yi-Ping Fu, Hyesik Kong, Moon Kyoo Jang, Temesgen Andargie, Woojin Park, Jae Lee, Ilker Tunc, Gerald J Berry, Charles C Marboe, Pali D Shah, Steven D Nathan, Michael B Keller, Sean Agbor-Enoh

“…As part of routine posttransplant clinical care, all patients underwent pulmonary function testing (PFT), surveillance bronchoscopy with bronchoalveolar lavage (BAL), transbronchial biopsy (TBBx), and donor-specific antibody testing (DSA). …”
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ANO5 p.I616F variant drives florid cemento-osseous dysplasia by disrupting transmembrane domain structure by Lanlan Zhang, Wenxi Jin, Yunfa Qin, Yonghui Zhang, Yemei Qian, Jingyi Li, Yu Liu, Yan’an Shi, Rongju Xie, Weihong Wang

“…Conclusion This study provides the first evidence that ANO5 variants (particularly p.I616F) may represent key genetic factors contributing to FCOD development in the Chinese population. The mutation likely disrupts the α-helical structure of ANO5 protein, impairing its catalytic function and potentially dysregulating bone remodeling processes in FCOD pathogenesis.…”
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Elbow-Hand Robotic Exoskeletons for Active and Passive Rehabilitation on Post-Stroke Patients: A Bioengineering Review by Mariela Vargas, Y. Vasquez, Daira de la Barra, Sandra Charapaqui, P. Tapia-Yanayaco, R. R. Maldonado-Gómez, L. M. Mendoza-Arias, Almendra Altatorre, Cristina Ccellccaro, M. Bedoya-Castillo, Renzo Charapaqui, A. Nacarino, Milton V. Rivera, Ricardo Palomares, M. Ramirez-Chipana, Jorge Cornejo, José Cornejo, Jhony A. de la Cruz-Vargas

“…The responsibility of assisting Physical Medicine and Rehabilitation (PM&R) doctors and the patient with passive exercises is a robotic system (RS); while active rehabilitation (AR) is applied regularly in late stages, it is like PR and its implications but requires the strength and support of the person to perform the exercises voluntarily. …”
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Comorbidity and progression of late onset Alzheimer's disease: A systematic review. by Miriam L Haaksma, Lara R Vilela, Alessandra Marengoni, Amaia Calderón-Larrañaga, Jeannie-Marie S Leoutsakos, Marcel G M Olde Rikkert, René J F Melis

“…Seven out of ten studies investigating cognition found comorbidities to be related to decreased cognitive performance. Five out of the seven studies investigating daily functioning showed an association between comorbidity burden and decreased daily functioning. …”
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Active bi- and multistability in cooperative microactuator systems by Manfred Kohl, Christoph Ament, Gowtham Arivanandhan, Tamara Bechtold, Peter Conrad, Sipontina Croce, Vincent Gottwald, Martin Hoffmann, Jonas Hubertus, Alexander Kopp, Zixiong Li, Michael Olbrich, Kirill Poletkin, Alberto Priuli, Gianluca Rizzello, Arwed Schuetz, Guenter Schultes, Stefan Seelecke, Lena Seigner, Hamid Shahsavari, Muhammad B. Shamim, Marian Sielenkämper, Georgino K. Tshikwand, Ulrike Wallrabe, Pascal Weber, Frank Wendler, Stephan Wulfinghoff

“…The smart coupling of microactuators to cooperative microactuator systems enables new functionalities like active bi- and multistability requiring no external force for switching between stable states. …”
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Targeting the NLRP3 in macrophages contributes to senescence cell clearance in radiation-induced skin injury by Gaoyu Liu, Yan Chen, Shijie Dai, Gang Wu, Fulong Wang, Wanchao Chen, Lingling Wu, Peng Luo, Chunmeng Shi

“…ScRNA sequencing, immunohistochemistry, immunofluorescence, qPCR, western blot, primary cell co-culture system and fluorescence microsphere phagocytosis assay were performed for the functional and mechanistic investigations. …”
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Good Manufacturing Practice Validation and Radiation Dosimetry for the Clinical Application of a Novel α7-nAChR Radioligand: [¹¹C]KIn83 by Zhisheng Jia, Martin Bolin, Anton Forsberg Morén, Prodip Datta, Heba Asem, Hans Ågren, Bengt Långström, Agneta Nordberg, Christer Halldin, Sangram Nag

“…Nicotinic acetylcholine receptor (α7-nAChR) plays a crucial role in cognitive functions like memory and attention. Positron emission tomography (PET) imaging of α7-nAChR is gaining attraction for understanding and monitoring central nervous system disorders, such as Alzheimer’s disease, Parkinson’s disease, and schizophrenia. …”
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Self-Choice Emotion Regulation Enhances Stress Reduction: Neural Basis of Self-Choice Emotion Regulation by Nozomi Imajo, Yutaka Matsuzaki, Akiko Kobayashi, Kohei Sakaki, Rui Nouchi, Ryuta Kawashima

“…Methods: Participants were 40 healthy adults who met the inclusion criteria; they performed self-choice emotion regulation, forced emotion regulation, and no emotion regulation (the control condition) while their brain activity was captured using a functional magnetic resonance imaging scanner. …”
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