METTL3/YTDHF1 Stabilizes MTCH2 mRNA to Regulate Ferroptosis in Glioma Cells by Hongjun Liu, Shasha Tan, Zhenyu Zhao, Xiaoping Tang, Zhou Li, Jian Qi

“…To assess the effects of MTCH2 knockdown and overexpression on glioma cell functions, we performed a series of functional assays, including cell viability, colony formation, and measurements of lipid reactive oxygen species (lipid ROS) and malondialdehyde (MDA) levels. …”
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Towards Parkinson’s Disease Detection Through Analysis of Everyday Handwriting by Jeferson David Gallo-Aristizabal, Daniel Escobar-Grisales, Cristian David Ríos-Urrego, Jesús Francisco Vargas-Bonilla, Adolfo M. García, Juan Rafael Orozco-Arroyave

“…Among daily activities that depend on proper upper limb control is the handwriting process, which has been studied in state-of-the-art research, mainly considering non-semantic drawings like spirals, geometric figures, cursive lines, and others. …”
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Mobile Apps to Prevent Violence Against Women and Girls (VAWG): Systematic App Research and Content Analysis by Md Hafizur Rahman, Nasimul Ghani Usmani, Pradip Chandra, Ridwana Maher Manna, Anisuddin Ahmed, Mohammad Sohel Shomik, Shams El Arifeen, Aniqa Tasnim Hossain, Ahmed Ehsanur Rahman

“…Future app development should prioritize cross-platform availability, offline functionality, public sector collaboration, and the integration of advanced technologies like artificial intelligence.…”
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Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) and Dental Pulp Stem Cells (DPSCs) Display a Similar Profile with Pericytes by Shao Yue Zhu, Chang Yong Yuan, Yi Fan Lin, Hao Liu, Yan Qi Yang, Hai Ming Wong, Cheng Fei Zhang, Peng Lai Wang, Min Gu

“…An in vitro Matrigel angiogenesis assay was conducted to reveal the ability of SHEDs, DPSCs, and pericytes to stabilize vascular-like structures. Quantitative real-time polymerase chain reaction (RT-qPCR) was performed to evaluate mRNA expression. …”
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Head-to-Head: Recombinant Human Prourokinase Versus Intravenous Thrombolytics in Acute Ischemic Stroke Within 4.5 Hours – A Systematic Review and Network Meta-Analysis of Randomize... by Muhammad Hassan Waseem MBBS, Zain ul Abideen MBBS, Areeba Shoaib MBBS, Muhammad Osama MBBS, Muhammad Abdullah Ali MBBS, Sania Aimen MBBS, Muhammad Wajih Ansari MD, Rowaid Ahmad MD, Muhammad Arslan Tariq MD, Ameer Haider Cheema MD, Aleeza Afzal MBBS, Pawan Kumar Thada MBBS

“…According to P-scores, Reteplase 18 + 18 mg ranked the best for excellent functional outcome (P-score = 0.89) and TNK 0.32 mg for good functional outcome (P-score = 0.99), while rhPro-UK 35 mg ranked the best for sICH (P-score = 0.89). …”
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Multi-sensor proximal remote sensing for cover crop biomass estimation at high and moderate spatial resolutions by Jyoti S. Jennewein, Brian W. Davis, Sarah Seehaver-Eagen, Jordan Nicolette, Josh Pittman, W. Dean Hively, Avi Goldsmith, Chris Hidalgo, Chris Reberg-Horton, Steven B. Mirsky

“…We assessed 11 species from three functional groups – grasses (n = 797), legumes (n = 264), and brassicas (n = 181) – using Random Forest (RF) models and four cross-validation strategies. …”
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Self-Reported Nonadherence Predicts Changes of Medication after Discharge from Hospital in People with Parkinson’s Disease by Francis Feldmann, Hannah M. Zipprich, Otto W. Witte, Tino Prell

“…However, patients who themselves made the changes were more likely to be nonadherent according to baseline SAMS. …”
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Impact of Active Fluidics System on RNFL and GCL in Phacoemulsification by Di Maria A, Ferraro V, Barone G, Vitali M, Tredici C, Gaeta A, Vinciguerra P, Confalonieri F

“…Changes in the computerized VF test showed variations, but these were not statistically significant.Conclusion: We found no significant changes in GCL nor retinal function. However, there was an increase in peripapillary RNFL, likely due to underestimation caused by lens opacification before surgery. …”
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PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study

“…Statistical comparisons were performed using the Mann-Whitney U test and Kaplan-Meier curves. …”
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Potential targets for the new anti-tuberculosis drug of the diarylquinoline group thiozonide by А. Yu. Savchenko, B. V. Shilov

“…Based on the study findings, the most likely binding targets were the subunits of bacterial ATP synthase. …”
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Botulinum toxin type A for amyotrophic lateral sclerosis lower limb spasm: two case reports by Qiang Duan, Chao Li, Chunxia Wei, Qian Wang, Bo Wang, Liangwen Sun, Yongjing He, Junxia Qin, Xiaoqun Huang

“…Abstract Background Patients with amyotrophic lateral sclerosis (ALS) often experience spasticity, which can severely affect their ability to perform basic activities like standing and walking, potentially diminishing their already compromised quality of life. …”
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Regulation of partial endothelial-to-mesenchymal transition by circATXN1 in ischemic diseases by Yue Li, Zhe Zheng, Yanze Li, Siyuan Fan, Lingyao Kong, Wanrong Fu, Zhonggen Li, Jianchao Zhang, Shuang Li, Zongtao Liu, Chao Liu, Jinhua Cao, Zhenxuan Hao, Lili Xiao, Youyou Du, Xiaofang Wang, Lu Gao

“…To address this, we performed circular RNA profiling of endothelial cells under ischemic-like conditions and identified a marked upregulation of a circular RNA, named circATXN1. …”
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Distinct patterns of cell adhesion, migration, and morphology in olfactory neuroepithelium cells of bipolar disorder patients by Alejandra Delgado-Sequera, Jose I. Pérez-Revuelta, Andres Caballero-García, MªCarmen Durán-Ruiz, Cristina Romero-Lopez-Alberca, Clara García-Mompó, Francisco González-Saiz, Manuel Rodríguez-Iglesias, Daniel Sanchez-Morillo, Patricia Robledo, Victor Perez, Esther Berrocoso, Maria Hidalgo-Figueroa

“…AUROC analysis identified proteins like PTK2 as potential diagnostic biomarkers, showing altered expression in both ONE cells and PBMCs. …”
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Immune evasion mechanisms in early-stage I high-grade serous ovarian carcinoma: insights into regulatory T cell dynamics by Joanna Mikulak, Sara Terzoli, Paolo Marzano, Valentina Cazzetta, Giampaolo Martiniello, Rocco Piazza, Maria Estefania Viano, Domenico Vitobello, Rosalba Portuesi, Fabio Grizzi, Mohamed A. A. A. Hegazi, Barbara Fiamengo, Gianluca Basso, Lara Parachini, Laura Mannarino, Maurizio D’Incalci, Sergio Marchini, Domenico Mavilio

“…The predicted Treg-cell interaction network, including crosstalk within tumor cells, facilitates Treg mobility and maturation while reinforcing their immunosuppressive function and persistence in the tumor. Moreover, their interactions with immune cells likely inhibit CD8 T cells and antigen-presenting cells, supporting tumor immune escape. …”
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Endoscopic retrograde cholangiopancreatography services in Sudan during wartime: Innovations in crisis by Abdelmounem Abdo, Salah Dafalla, Mohammed Bushra, Rodwan Mustafa, Reem Hamad, Ahmed Rafei, Mohamed Jaafer, Rawan Bidab, Waleed Gamus Ojan, Mohammed Ganim, Hala Abdalla

“…ERCP services are well-established primarily in South Africa and Egypt. Countries like Nigeria, Uganda, Rwanda, Ethiopia, and Kenya have sustained ERCP services over the past 5 years. …”
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Molecular Insights into the Superiority of Platelet Lysate over FBS for hASC Expansion and Wound Healing by Sakurako Kunieda, Michika Fukui, Atsuyuki Kuro, Toshihito Mitsui, Huan Li, Zhongxin Sun, Takayuki Ueda, Shigeru Taketani, Koichiro Higasa, Natsuko Kakudo

“…In a murine wound model, PL-treated wounds showed accelerated healing, characterized by thicker dermis-like tissue formation and increased angiogenesis. …”
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Systematic review of physiological and psychological outcomes of surgery for pectus excavatum supporting commissioning of service in the UK by Jamie Walsh, Ross Walsh, Karen Redmond

“…Twenty-one studies investigated pulmonary function at rest. There was no change in forced vital capacity or forced expiratory volume in 1 second following open repair and transient reductions followed closed repair. …”
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Identification of potential drug targets for achalasia from genetic insights: a Mendelian randomization study by Kai Xiong, Hao Fang, Caihong Song, Dilihumaer Tuerxun, Peng Zhang

“…Abstract Background Achalasia (AC) is an esophageal dyskinetic disorder characterized by loss of function of ganglion cells of the intermuscular plexus of the distal esophagus and lower esophageal sphincter. …”
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Innovative Approaches in Dental Care: Electrical Impedance Analysis (EIA) for Early Caries Detection by Liliana Sachelarie, Ioana Romanul, Daniela Domocos, Mihaela Moisa, Emilia-Albinita Cuc, Raluca Iurcov, Carmen Stadoleanu, Loredana Liliana Hurjui

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The Gene Expression Profile of Milk Somatic Cells of Small Ruminant Lentivirus-Seropositive and -Seronegative Dairy Goats (<i>Capra hircus</i>) During Their First Lactation by Joanna Pławińska-Czarnak, Alicja Majewska, Joanna Magdalena Zarzyńska, Jarosław Kaba, Emilia Bagnicka

“…RT-qPCR confirmed changes for <i>DUSP26</i>, <i>SCARA3</i>, and <i>APBB2</i>. Functional analysis indicated associations with immune processes and HIV-like pathways. …”
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