Detour-Straddle 3D-like path planning of unmanned mining truck in open pit mines based on optimized ant colony algorithm by Mingyu GAO, Jiusheng BAO, Yan YIN, Deping HU, Kekun ZHANG, Chenzhong ZHU, Maosen WANG, Kai WANG

“…Then, the initial pheromone distribution of ant colony algorithm is optimized to improve the goal orientation of the algorithm, and the optimal and worst path is considered in the improved pheromone updating strategy to improve the performance and efficiency of path search. Adaptive multi-step movement mode is introduced, and a multi-objective heuristic function is designed to introduce cross-obstacle evaluation. …”
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Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway by Hai-Bo Zhang, Ying Zeng, Guo Wang

“…Results The expression level of PVT1 in BC tissues of luminal and basal-like subtypes was significantly higher than that in paracancerous tissues. …”
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Skin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivo. by Katrin Hack, Louise Reilly, Colin Palmer, Kevin D Read, Suzanne Norval, Robert Kime, Kally Booth, John Foerster

“…Since PPAR β/δ has pleiotropic functions in metabolism, skin-targeted inhibition offer the potential of reducing systemic adverse effects. …”
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Associations of Vocal Features, Psychiatric Symptoms, and Cognitive Functions in Schizophrenia by Natsuyama T, Chibaatar E, Shibata Y, Okamoto N, Cruz Victorino JN, Ikenouchi A, Shibata T, Yoshimura R

“…We analyzed voice data from 14 participants to see if there were links between their vocal features, psychiatric symptoms, and cognitive functions. Our findings showed that poorer cognitive abilities, like memory and attentional control, negatively correlated with certain vocal characteristics. …”
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Performance investigation of UN spherical fuel elements in MSR-SF by Haiqing Zhang, Changqing Cao, Peng Wang, Ziwei Li, Xuzhong Kang, Jun Lin

“…UN fuels offer advantages like higher thermal conductivity and heavy metal density compared to traditional uranium oxide (UO2). …”
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Ziziphi Spinosae Semen Flavonoid Ameliorates Hypothalamic Metabolism and Modulates Gut Microbiota in Chronic Restraint Stress-Induced Anxiety-like Behavior in Mice by Yan Yan, Ni Zhao, Jiaying Liu, Shengmei Zhang, Yinjie Zhang, Xuemei Qin, Kefeng Zhai, Chenhui Du

“…ZSSF treatment dramatically reduced anxiety-like behaviors, exerted sedative–hypnotic effects, increased hippocampal 5-HT and 5-HTP, and enhanced intestinal barrier function through inhibiting colon ZO-1, Claudin-1, and Occludin expression and reducing TNF-α, IL-6, and IL-1β levels. …”
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Tousled-like kinase loss confers PARP inhibitor resistance in BRCA1-mutated cancers by impeding non-homologous end joining repair by Min-ah Kim, Banseok Kim, Jihyeon Jeon, Jonghyun Lee, Hyeji Jang, Minjae Baek, Sang-Uk Seo, Dongkwan Shin, Anindya Dutta, Kyung Yong Lee

“…The recruitment of proteins that promote NHEJ and HR to DSBs was analyzed using immunostaining, live-cell imaging following laser-induced microirradiation, and FokI-inducible single DSB generation. Loss-of-function experiments were performed in multiple human cancer cell lines using siRNA-mediated knockdown or CRISPR-Cas9 gene knockout. …”
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Nutritional priorities to support GLP-1 therapy for obesity: A joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medic... by Dariush Mozaffarian, Monica Agarwal, Monica Aggarwal, Lydia Alexander, Caroline M. Apovian, Shagun Bindlish, Jonathan Bonnet, W. Scott Butsch, Sandra Christensen, Eugenia Gianos, Mahima Gulati, Alka Gupta, Debbie Horn, Ryan M. Kane, Jasdeep Saluja, Deepa Sannidhi, Fatima Cody Stanford, Emily A. Callahan

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Benchmarking biomolecular force fields for molecular dynamics simulations of native fold and enzymatic activity of SARS-CoV-2 papain-like protease by Kateryna O. Lohachova, Alexander Kyrychenko, Oleg N. Kalugin

“…The papain-like protease (PLpro) of the SARS-CoV-2 coronavirus is crucial for viral processing and disrupting the immune response. …”
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Thermal performance evaluation of recycled salt hydrates through T-history by Charles A. Wesemann, Tessa Junggeburth, H.J.H. Brouwers

“…The addition of titania increases the number of functional cycles of recycled samples but diminishes performance in analytical samples. …”
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The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases by Yezhou Ding, Mingyang Feng, Wanqing Chi, Xiaoyin Wang, Baoyan An, Kehui Liu, Shike Lou, Xiaolin Wang, Hui Wang

“…Abstract Background Methyltransferase-like (METTL) family protein plays a crucial role in the progression of malignancies. …”
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Relativistic Linear Response in Quantum-Electrodynamical Density Functional Theory by Lukas Konecny, Valeriia P. Kosheleva, Heiko Appel, Michael Ruggenthaler, Angel Rubio

“…Moreover, we show that a new type of spin-orbit-like (SO) cavity-mediated interaction appears under the relativistic description of the coupling of matter with quantized cavity modes. …”
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Evaluating serum periostin and YKL-40 as biomarkers for airway remodeling and hyperresponsiveness in pediatric asthma by Su Ji Kim, MD, Youn Joo Choi, MD, Man Yong Han, MD, PhD, Il Tae Hwang, MD, PhD, Hey-Sung Baek, MD, PhD

“…Background: Periostin and human chitinase-3-like protein 1 (YKL-40) have been suggested to be involved in the development of airway fibrosis and remodeling. …”
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TAAR8 in the Brain: Implications for Dopaminergic Function, Neurogenesis, and Behavior by Taisiia S. Shemiakova, Alisa A. Markina, Evgeniya V. Efimova, Ramilya Z. Murtazina, Anna B. Volnova, Aleksandr A. Veshchitskii, Elena I. Leonova, Raul R. Gainetdinov

“…<b>Results:</b> During the study, we found a number of alterations specific to tTAAR8-KO mice compared to controls. tTAAR8-KO mice demonstrated better short-term memory, more depressive-like behavior, and higher body temperature. Also, we observed changes in the dopaminergic system, brain electrophysiological activity, and adult neurogenic functions in mice lacking <i>Taar8</i> isoforms. …”
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PHENOTYPIC PROFILE AND FUNCTIONAL ACTIVITY OF MONOCYTES IN THE PATIENTS WITH ACUTE PANCREATITIS by A. A. Savchenko, A. G. Borisov, D. E. Zdzitovetskiy, I. V. Kudryavtsev, A. Yu. Medvedev, A. V. Moshev, I. I. Gvozdev

“…The aim of this study was to evaluate some features of subpopulational profile and functional activity of monocytes in patients with acute pancreatitis. …”
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Climate Change Risk, Performance, and Value Added in Agricultural Sector by Ramin Amani, Zanko Ghorbani, Zana Mozaffari

“…Results and Discussion The results of this research show that both climate change performance index variables and climate change risk have a positive and significant effect on the added value of the agricultural sector in all three functional groups and all deciles. …”
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Effects of genetic diversity on physicochemical and functional properties of soybean proteins by Shima Momen, Sanjana Sawant, Benjamin D. Fallen, Audrey L. Girard

“…SDS-PAGE showed unique patterns for β-conglycinin and glycinin subunits across different genotypes, linking these differences to solubility (60–85 %), hydrophobicity, and overall functionality. Some genotypes had better foaming capacity (up to 58 %) due to balanced protein structures and higher surface hydrophobicity (H0 up to 140 × 103), while others performed poorly, with foaming capacity as low as 35 %, likely due to missing subunits and reduced hydrophobicity (H0 below 65 × 103). …”
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Hygric performance of new building components for vertical green gardens by Pavel Kopecký

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Relationship between seawater temperature, brain GnRH-like peptide expression, and gonadal development in wild bigfin reef squid (Sepioteuthis lessoniana) by Umina Kubo, Lee Jaewoo, Ryosuke Murata, Takashi Aoshima, Yuji Mushirobira, Kiyoshi Soyano

“…Nevertheless, knowledge of its specific functions in cephalopod reproduction remains limited. …”
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Seismic Vibration Control and Multi-Objective Optimization of Transmission Tower with Tuned Mass Damper Under Near-Fault Pulse-like Ground Motions by Ying Lin, Tao Liu

“…In addition, ANN fitting can accurately predict the nonlinear relationship between TMD parameters and objective functions. Through multi-objective optimization with the NSGA-III algorithm, TMD can simultaneously and significantly reduce different peak responses of transmission towers under near-fault pulse-like ground motions in a cost-effective manner.…”
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