Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. by Erin N Smith, Daniel L Koller, Corrie Panganiban, Szabolcs Szelinger, Peng Zhang, Judith A Badner, Thomas B Barrett, Wade H Berrettini, Cinnamon S Bloss, William Byerley, William Coryell, Howard J Edenberg, Tatiana Foroud, Elliot S Gershon, Tiffany A Greenwood, Yiran Guo, Maria Hipolito, Brendan J Keating, William B Lawson, Chunyu Liu, Pamela B Mahon, Melvin G McInnis, Francis J McMahon, Rebecca McKinney, Sarah S Murray, Caroline M Nievergelt, John I Nurnberger, Evaristus A Nwulia, James B Potash, John Rice, Thomas G Schulze, William A Scheftner, Paul D Shilling, Peter P Zandi, Sebastian Zöllner, David W Craig, Nicholas J Schork, John R Kelsoe

“…To demonstrate that this result is not likely to be a false positive, we analyze replication rates in a large meta-analysis of height and show that, in a large enough study, associations replicate as a function of power, approaching a linear relationship. …”
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Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells in Association with Arthroscopic Microfracture of Knee Articular Cartilage Defects: A Pilot Randomized Controlled Tr... by Michele Venosa, Francesco Calafiore, Manuel Mazzoleni, Emilio Romanini, Simone Cerciello, Vittorio Calvisi

“…An additional arthroscopic procedure, performed in four patients for a subsequent meniscal lesion, let us evaluate cartilage evolution by performing a macro/microscopical assessment on cartilage biopsy specimens. …”
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Differentiated Approach to the Surgical Treatment of Chronic Uveitis in Juvenile Idiopathic Arthritis by A. V. Tereshchenko, I. G. Trifanenkova, M. S. Tereshchenkova, E. V. Erokhina, N. N. Yudina

“…High functional results in children with uveitis associated with JIA were achieved due to modern methods of preoperative diagnosis, advanced surgical techniques, as well as proper management of the patients in the postoperative period.…”
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Micro-RNA profiling in human serum reveals compartment-specific roles of miR-571 and miR-652 in liver cirrhosis. by Christoph Roderburg, Tobias Mollnow, Brenda Bongaerts, Natalia Elfimova, David Vargas Cardenas, Katharina Berger, Henning Zimmermann, Alexander Koch, Mihael Vucur, Mark Luedde, Claus Hellerbrand, Margarete Odenthal, Christian Trautwein, Frank Tacke, Tom Luedde

“…In functional experiments we evaluated the relationship between alterations of miRNA serum levels and their role in distinct cellular compartments involved in hepatic cirrhosis.…”
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Microbial Interconnections in One Health: A Critical Nexus Between Companion Animals and Human Microbiomes by Stylianos Skoufos, Elisavet Stavropoulou, Christina Tsigalou, Chrysoula (Chrysa) Voidarou

“…The dynamic interplay between a host’s microbiome, the microbiomes of other hosts, and environmental microbial communities profoundly influences the host health, given the essential physiological functions the microbiome performs within the organism. …”
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The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits by T. I. Shashkova, D. D. Gorev, E. D. Pakhomov, A. S. Shadrina, S. Zh. Sharapov, Y. A. Tsepilov, L. C. Karssen, Y. S. Aulchenko

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Conscientious Objection Based on Patient Identity by John Dinelli

“…These additional qualities create trust and comfort patients.[8] Also, the virtuous physician exemplifies trustworthiness, integrity, discernment, compassion, patience, and conscientiousness.[9] Others even include theological virtues such as faith, hope, and charity as important characteristics in a physician’s practice.[10] While not an exhaustive list of the values that compose a virtuous physician, these standards are the basic requirements for physician to exemplify virtue and perform the job’s functions well. One may argue that theological virtues like faith, hope, and charity support the conscientious objection because physicians are virtuous when they are faithful, or loyal to their religious beliefs. …”
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A transcriptomic landscape analysis of human necrotizing enterocolitis: Important roles of immune infiltration by Zhuojun Xie, Quan Kang, Yulu Shi, Junbao Du, Hao Jiang

“…For RNA‐Seq, DEseq2 algorithm was used to identify differentially expressed genes (DEGs) and to perform functional enrichment analysis. Immune infiltration was analyzed by CIBERSORT algorithm. …”
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A comprehensive analysis of a patient with anterior interosseous nerve neuropathy by Josivaldo De Souza Lima, Pedro Valdivia-Moral, Sandra Mahecha-Matsudo, Victor Keihan Rodrigues Matsudo, Mauro Rumbaut, Gerson Ferrari, Frano Giakoni-Ramirez

“…Clinical case: A 44-year-old right-handed man, physically active, participates in functional training thrice weekly and amateur soccer. …”
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TelescopeML. II. Convolutional Neural Networks for Predicting Brown Dwarf Atmospheric Parameters by Ehsan (Sam) Gharib-Nezhad, Hamed Valizadegan, Natasha E. Batalha, Miguel J. S. Martinho, Ben W.P. Lew

“…For Ross 458C, our CNN model predicts the $\mathrm{log}\,g$ accurately but tends to overestimate T _eff by ≈150 K and [M/H] by ≈1.0 dex compared to the previous modelings, which likely happens because our model grids lack disequilibrium chemistry and clouds. …”
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Evaluation of the Toumai robotic system in partial nephrectomy and key system features by Gaurab Pokhrel, Haoke Zheng, Jin Tao, Yafeng Fan, Yunlong Liu, Biao Dong, Shuanbao Yu, Xuepei Zhang

“…These preliminary results suggest that partial nephrectomy can be safely performed using the Toumai robotic system. The system’s advanced features, including sensory feedback, high-frequency response, and enhanced imaging technologies, likely contributed to favorable surgical outcomes with minimal complications. …”
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Clinical efficacy of different therapeutic options for knee osteoarthritis: A network meta-analysis based on randomized clinical trials. by Xiao Chen, Yuanhe Fan, Hongliang Tu, Yuan Luo

“…Two researchers independently performed literature screening, data extraction, data collection and organization, and quality assessment. …”
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Study of Expression of <i>MST3</i> in Myeloid Leukaemia by Boro Arthi, Krishnaswamy Sujatha, Sridhar Gopal, Balasubramanian Balamuralikrishnan, Meyyazhagan Arun, Pappuswamy Manikantan, Palanisamy Sampathkumar, Arumugam Vijaya Anand

“…<i>MST3</i> is a gene of the GCK family that has a role in apoptosis, along with other cellular functions like cellular differentiation, cell cycle, metabolism, and others. …”
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ROLE OF PRO-INFLAMMATORY CYTOKINE GENE POLYMORPHISMS IN PATIENTS WITH EARLY-ONSET VENOUS THROMBOEMBOLISM by A. P. Polyakova, V. M. Shmeleva, M. N. Blinov, V. E. Soldatenkov, V. D. Kargin, L. P. Papayan, S. I. Kapustin

“…A retrospective analysis was performed for a group of 180 patients with early-onset VTE, and 150 healthy. …”
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Preserving Paratenon in Acute Achilles Tendon Repair: A 5-Year Follow-Up by Mohammad Hossein Chegini Kord MD, Alireza Ebrahimi MD, Gregory R. Waryasz MD, Soheil Ashkani-Esfahani MD, Mohammad Razi MD

“…Conclusion: Preserving the Paratenon during AT repair showed satisfactory functional and clinical outcomes without any case of the wound complications that are common after open repairs. …”
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Dynamics of post fire plant community assembly in Doñana coastal dunes by Sergio Chozas, André F. Mira, Manuel Serrano, Nagore G. Medina, Joaquín Hortal, María Cruz Díaz-Barradas

“…However, some ecosystems, like Mediterranean scrublands, recover quickly due to species’ adaptations to frequent fire regimes. …”
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Characterization of Bimi^® Broccoli as a Convenience Food: Nutritional Composition and Quality Traits Following Industrial Sous-Vide Processing by Elisa Canazza, Christine Mayr Marangon, Dasha Mihaylova, Valerio Giaccone, Anna Lante

“…This study investigates Bimi^® (<i>Brassica oleracea</i> Italica × Alboglabra), a hybrid between kailan and conventional broccoli, to evaluate its compositional, functional, and sensory properties in relation to industrial sous-vide processing and refrigerated storage. …”
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Green synthesis of rGO/MgO nanocomposite using Hylocereus polyrhizuspeel extract for antibacterial activity and photocatalytic dye degradation study by Sunil Kumar Abel, Saranya Amirtharajan, Arulprakasajothi Mahalingam, Srimanickam Baskaran, Sakthivel Pandurengan

“…The SEM portrays the agglomerated granular structure has larger scale web like structure are highly interconnected with large voids. …”
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Empowering Quality of Recommendations by Integrating Matrix Factorization Approaches With Louvain Community Detection by Srilatha Tokala, Murali Krishna Enduri, T. Jaya Lakshmi, Ashu Abdul, Jenhui Chen

“…The experimental analysis is performed on five different diverse datasets to enhance the quality of the recommendation. …”
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Impact of Varied Lead Concentrations on Lead Accumulation in the Body, Heart and Gill Damage of Milkfish (Chanos chanos) by Reski Wahyuni Sukardi, Muhammad Iqbal Djawad, Hasni Yulianti Azis, Sharifah Raina Manaf

“…Pb exposure rapidly damages and disrupts milkfish's biological functions, influencing survival and growth. Pb exposure with doses 8 mL.L-1 significantly affected juvenile milkfish within approximately 60 min.…”
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