Characterizing stroke presenting to a regional referral hospital before and during the COVID-19 pandemic in Uganda: a retrospective analysis by Josephine Nambi Najjuma, Timothy Mwanje Kintu, Jane Nakibuuka, Mark Kaddumukasa, Scovia N. Mbalinda, Martin Kaddumukasa, Christopher Burant, Shirley Moore, Martha Sajatovic, Edwin Nuwagira

“…A significant increase in acute ischemic stroke cases was observed in 2020, with no significant differences in stroke severity or functional ability between the two years. Clinical parameters such as admission oxygen saturation, blood sugar, temperature, and Glasgow Coma Scale (GCS) score, along with complications like aspiration pneumonia and infections, correlated with mortality. …”
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Exploring the role of ATP-binding cassette transporters in tomato (Solanum lycopersicum) under cadmium stress through genome-wide and transcriptomic analysis by Syed Salman Hashmi, Lubna, Saqib Bilal, Rahmatullah Jan, Saleem Asif, Ashraf M. M. Abdelbacki, Kyung-Min Kim, Ahmed Al-Harrasi, Sajjad Asaf

“…Specific genes, including Groups 3 and 5 members, were upregulated under Cd exposure, suggesting their functional roles in mitigating Cd toxicity. The study revealed differential expressions of various SlABC genes encoding ATP binding cassette transporters, including the upregulation of several genes like Solyc08g067620.2, Solyc08g067610.3, Solyc12g019640.2, Solyc06g036240.2, and Solyc05g053610.2 in response to different concentrations of Cd. …”
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A Legendre–Galerkin spectral method for option pricing under regime switching models by Abdelmajid Ezzine, Abdellah Alla, Nadia Raissi

“…The spatial discretization of the problem is performed using the Legendre–Galerkin spectral method based on Fourier-like basis functions, while the temporal discretization is based on a Crank–Nicolson scheme. …”
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Exploring the role of neutrophil extracellular traps in neuroblastoma: identification of molecular subtypes and prognostic implications by Can Qi, Can Qi, Ziwei Zhao, Lin Chen, Le Wang, Yun Zhou, Guochen Duan, Guochen Duan

“…Differential analysis was performed to identify DEGs between subtypes. Functional items and related pathways of DEGs were identified using enrichment analysis. …”
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Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study. by Sana Suri, Scott T Chiesa, Enikő Zsoldos, Clare E Mackay, Nicola Filippini, Ludovica Griffanti, Abda Mahmood, Archana Singh-Manoux, Martin J Shipley, Eric J Brunner, Mika Kivimäki, John E Deanfield, Klaus P Ebmeier

“…Cognitive outcomes were performance on verbal memory, semantic fluency, working memory, and executive function tests. …”
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Evaluation of MODIS and VIIRS BRDF Parameter Differences and Their Impacts on the Derived Indices by Chenxia Wang, Ziti Jiao, Yaowei Feng, Jing Guo, Zhilong Li, Ge Gao, Zheyou Tan, Fangwen Yang, Sizhe Chen, Xin Dong

“…Even though the MODIS and VIIRS BRDF products originate from sensors and algorithms with similar designs, the consistency between BRDF parameters for different sensors is still unknown, and this likely affects the consistency and accuracy of various downstream parameter inversions. …”
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Regulation of receptor interacting protein kinase 1-mediated apoptosis by cordycepin attenuated hypoxia/reoxygenation-induced renal tubular epithelial cell injury by Xiu-tao Han, Xiu-zhao Fan, Zhi-bo Zhao, Jing-yu Zhao, Jun-hu Li, Fang Zhang, Gai-ying Jiang, Li-jun Zhang, Fa-hui Chen, Meng-qi Bai, Xiao-shuang Zhou

“…KEGG enrichment analysis results showed that they played some roles in signaling pathways of Toll-like receptor, necroptosis, nucleotide-binding oligomerization domain （NOD）-like receptor, nuclear factor-κB （NF-kB）, tumor necrosis factor （TNF） and cell apoptosis, etc. …”
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A RARE DISEASE ASSOCIATED WITH IG4, CHARACTERIZED BY SYSTEMIC AMYLOIDOSIS AND LYMPHOPLASMACYTIC CELL DOMINANCE: A CASE PRESENTATION by Şerife Emre Ünsal, Mihriban Yıldırım, Hacı Ahmet Aslaner, Neslihan Mandacı Şanlı, Gülşah Akyol, Muzaffer Keklik, Özlem Canöz, Olgun Kontaş, Ali Ünal

“…A tru-cut biopsy was performed, which was reported as amyloidosis. The biopsy revealed an increase in plasma cells. …”
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Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window by Amir Hossein Ahmadi Hekmatikar, Arsham Entesari, Hossein Shirvani

“…Additionally, it has been discovered that lactate metabolism is essential for the function of anti-tumor immune cells (Ahmadi Hekmatikar et al., 2023; Heuser et al., 2023). …”
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Explicit demonstration of the equivalence between DFT+U and the Hartree-Fock limit of DFT+DMFT by Alberto Carta, Iurii Timrov, Peter Mlkvik, Alexander Hampel, Claude Ederer

“…Finally, we showcase the versatility of our approach by going beyond the commonly used atomic orbital-like projectors by performing DFT+U calculations for VO_{2} using a special set of bond-centered Wannier functions.…”
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On Microservice-Based Architecture for Digital Forensics Applications: A Competition Policy Perspective by Fragkiskos Ninos, Konstantinos Karalas, Dimitrios Dechouniotis, Michael Polemis

“…In this context, cloud resource orchestration platforms like Kubernetes provide augmented functionalities, such as resource scaling, load balancing, and monitoring, supporting every stage of the application’s lifecycle. …”
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Alternative Splicing Regulation of Cancer-Related Pathways in Caenorhabditis elegans: An In Vivo Model System with a Powerful Reverse Genetics Toolbox by Sergio Barberán-Soler, James Matthew Ragle

“…A big proportion of these events are functional, conserved, and under strict regulation either across development or other conditions. …”
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VOPP1 as a Novel Susceptibility Gene in Rheumatoid Arthritis: Insights Into Its Mechanisms From Mendelian Randomization and Experimental Validation by Wu W, Cai H, Nan Y, Tang J, Wang Y

“…Synovial tissue samples were collected from patients undergoing joint surgery at the Affiliated Hospital of Nantong University. Functional validation of the candidate gene vesicular overexpressed in cancer pro-survival protein 1 (VOPP1) was performed in vitro using rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs), and in vivo in a collagen-induced arthritis (CIA) rat model. …”
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Whole-exome sequencing identified a novel heterozygous variant in UBAP2L in a Chinese family with neurodevelopmental disorder characterized by impaired language, behavioral abnorma... by Qi Yang, Qi Yang, Qiang Zhang, Qiang Zhang, Xunzhao Zhou, Xunzhao Zhou, Juntan Feng, Shujie Zhang, Shujie Zhang, Li Lin, Li Lin, Shang Yi, Shang Yi, Zailong Qin, Zailong Qin, Jingsi Luo, Jingsi Luo, Jingsi Luo

“…To date, only one report has documented 12 loss-of-function variants in UBAP2L, all of which were identified as de novo variants. …”
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Accelerated risk of renal disease progression in pre-ESRD patients with proton pump inhibitors use: a nationwide population-based study by Chien-Huei Huang, Chih-Jung Tsai, Chien-Chou Su, Chi-Tai Yen, Ju-Ling Chen, Ching-Lan Cheng

“…Most evidence was to evaluate the risk of PPIs in patients with normal renal function and in the absence of the moderate to advanced chronic kidney disease (CKD). …”
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Ultrawide implants for immediate molar extraction socket versus standard diameter fixtures in healed alveolar ridges of missing molars, one-year postloading evaluation: A randomize... by Farhan Durrani, Ekta Kumari, Anju Gautam, Sakshi Agarwal, Rashika Mularisekar, Shraddha Shilpi

“…Radiographic assessments and Osstell device measurements were performed at implant placement, 3 months postrestoration, and 1 year after prosthetic function. …”
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Synergistic Effects of Aldehyde Dehydrogenase 2 Polymorphisms and Alcohol Consumption on Cognitive Impairment after Ischemic Stroke in Han Chinese by Ying Yu, Jie Gao, Shasha Wang, Heng Lv, Liping Xiao, Hengyuan Shi, Xianjie Jia

“…We revealed that individuals with the ALDH2 wild-type genotype were more likely to have high MoCA scores than those with the mutant and heterozygous types (p=0.034). …”
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Phase II open label study of valproic acid in spinal muscular atrophy. by Kathryn J Swoboda, Charles B Scott, Sandra P Reyna, Thomas W Prior, Bernard LaSalle, Susan L Sorenson, Janine Wood, Gyula Acsadi, Thomas O Crawford, John T Kissel, Kristin J Krosschell, Guy D'Anjou, Mark B Bromberg, Mary K Schroth, Gary M Chan, Bakri Elsheikh, Louise R Simard

“…Clear decline in motor function occurred in several subjects in association with weight gain; mean fat mass increased without a corresponding increase in lean mass. …”
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Artificial Intelligence Sexual Innovation and the Marriage Covenant: An Ethical and Theological Assessment by Brian Kapembwa Sinyangwe

“…A topical moral discussion lies in the development of sexual robots that can perform conjugal functions. However, the Bible presents the concept of sexuality as a privilege exercised within the precincts of the same species in heterosexual relationships. …”
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Genome-wide identification and characterization of Ethylene-Insensitive 3 (EIN3/EIL) gene family in Camellia oleifera. by Shihang Huang, Fang Li, Caiqin Li, Xiaobei Li, Qiuling Pan, Yongquan Li, Wenpei Song, Juan Li

“…Ethylene signaling, mediated by Ethylene-Insensitive3/Ethylene-Insensitive 3-like (EIN3/EIL) transcription factors encoded by a multigene family, plays a pivotal role in plant organ abscission. …”
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