Rethinking the neurological examination I: static balance assessment by Péricles A. Maranhão-Filho, Eliana Teixeira Maranhão, Marcos Martins da Silva, Marco Antônio Lima

“…The authors advocate a modernization of the neurologic exam with regard to the evaluation of static equilibrium through the application of some easily performed and interpreted bedside maneuvers like the Clinical Test of Sensory Integration and Balance - modified and the Functional Reach Test. …”
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A modern approach to identifying and characterizing child asthma and wheeze phenotypes based on clinical data. by Bronwyn K Brew, Flaminia Chiesa, Cecilia Lundholm, Anne Örtqvist, Catarina Almqvist

“…Characterization was then performed with regression analyses using diagnostic data: lung function and immunological biomarkers, parent-reported medication use and risk-factors. …”
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Investigating the Compatibility of Various Components in Marine Low-Sulfur Fuel Oil by Molecular Dynamics Simulations by Daping Zhou, Haijun Wei, Shuye Xue, Ye Qiu, Shen Wu, Haijie Yu

“…Specifically, asphaltene is more likely to self-aggregate, as shown by the increase in peak height in the radial distribution function of the asphaltene-asphaltene pair. …”
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Anterior clinoid process metastasis with sudden loss of vision: role of emergency optic nerve decompression by Marta Rico-Pereira, Fernando Muñoz-Hernández

“…We present an unusual case of anterior clinoid process metastasis with sudden deterioration of visual function requiring emergency optic nerve decompression, resulting in visual recovery. …”
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Double accusative cases in old Persian constructions by Sahar Vahdati Hosseinian, Ehsan Changizi, Jaleh Amouzgar Yeghaneh, Ameneh Zaheri Abdvand

“…Depending on the meaning and context of a sentence, it can perform different functions and express various semantic roles. …”
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Methodology for the identification of bioactive and marker peptides in the organs of cattle and pigs by D. V. Khvostov, N. L. Vostrikova, I. M. Chernukha

“…The development of general conception methodology for the meat-based functional food compositions is especially relevant today due to the growing consumers’ interest and attention to their health. …”
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ISGylation and E3 ubiquitin ligases: an Atlantic salmon genetic perspective by Unni Grimholt, Hilde Sindre, Arvind Y. M. Sundaram, Arvind Y. M. Sundaram

“…Here, E1-activating enzymes, E2-conjugating enzymes, and E3 ligases attach the ubiquitin chain to molecules to be functionally modified or destined for degradation. One specialized version of this pathway is performed by ISG15, a ubiquitin-like protein modifier that works through a process called ISGylation. …”
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On the determination of the interaction time of GeV neutrinos in large argon gas TPCs by A. Saá-Hernández, D. González-Díaz, J. Martín-Albo, M. Tuzi, P. Amedo, J. Baldonedo, C. Benítez, S. Bounasser, E. Casarejos, J. Collazo, A. Fernández-Prieto, D. J. Fernández-Posada, R. Hafeji, S. Leardini, D. Rodas-Rodríguez, A. L. Saborido, A. Segade, A. Slater

“…We show that the neutrino interaction time can be reconstructed from the primary scintillation signal with a precision in the range of 1–2.5 ns $$(\sigma )$$ ( σ ) for point-like deposits with energies down to 5 MeV. A similar response is observed for minimum-ionizing particle tracks extending over lengths of a few meters. …”
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selSeq: A method for the enrichment of non-polyadenylated RNAs including enhancer and long non-coding RNAs for sequencing. by Jason D Limberis, Alina Nalyvayko, Joel D Ernst, John Z Metcalfe

“…For example, enhancer RNAs are long non-coding RNAs that perform enhancer-like functions, are bi-directionally transcribed, and usually lack polyA tails. …”
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The Role of Pyroptosis‐Related Gene Signature and Immune Infiltration in Juvenile Dermatomyositis by Qiao W, Zhu C, Huang D, Liu Y, Wang Z, Zhu T, Song Q, Yang X, Wang Y, Wang Y

“…Functional enrichment analysis, immune cell infiltration analysis, gene set variation analysis (GSVA), and gene set enrichment analysis (GSEA) were performed to elucidate the potential roles of PR-DEGs in JDM pathogenesis.Results: A total of 2526 common DEGs were identified, among which 12 PR-DEGs were identified, with CASP1, IRF1, NOD2, and PYCARD identified as hub PR-DEGs. …”
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Mechanism of <italic>Hindu Datura</italic> in the Treatment of Rheumatoid Arthritis from the Perspective of Network Pharmacology by Changlong FU, Yangyang MEI, Xihai LI, Zhiwei QIU, Changxing CHEN, Chunsong ZHENG

“…Objective:To construct the active component target of <italic>Hindu datura</italic> and the disease target of rheumatoid arthritis by using network pharmacology, to predict the specific molecular signal and pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis, and to analyze its potential therapeutic target and molecular mechanism.Methods:All the chemical components of <italic>hindu datura</italic> were summarized and screened through Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP)database, retrieval was performed with the preset oral bioavailability(OB)≥30%and drug like(DL)≥0.18.Uniprot database was used to screen the entire correlation basis of the effective chemical compound.After screening the disease target with"rheumatoid arthritis"as the retrieval word using GeneCards and OMIM database, the superimposed target area between the drug target of <italic>hindu datura</italic> and the disease target of rheumatoid arthritis was summarized and analyzed, and it could be used as the prediction target gene of <italic>hindu datura</italic> for treating rheumatoid arthritis.Network targets were constructed and analyzed for the exported data based on Cytoscape 3.7.1 software and STRING 7.8 database.Finally, GO functional enrichment analysis and KEGG signal pathway analysis were performed to further screen the main targets and signal pathways.Results:①Through screening and analysis, 27 effective compounds, 318 corresponding target genes and 125 predicted target genes were obtained for the treatment of rheumatoid arthritis.②The core genes in PPI network mainly included JUN, AKT1, RELA, MAPK1, etc.③GO functional enrichment analysis showed that the biological process(BP)for the treatment of rheumatoid arthritis by <italic>hindu datura</italic> mainly involves response to lipopolysaccharide, response to lipopolysaccharide, response to molecule of bacterial origin, response to metalion, response to oxidative stress, response to steroid hormone, cellular response to oxidative stress, reactive oxygen species metabolic process, response to oxygen levels, etc..The cell component(CC)consisted of membrane raft, membrane region, plasma membrane raft and presynaptic membrane; molecular functions(MF)mainly involved the nuclear receptor activity, transcription factor activity(direct ligand regulated sequence-specific DNA binding), steroid hormone receptor activity, cytokine receptors, cytokine activity, DNA-binding transcription activator activity, RNA polymeraseⅡtranscription factor binding, kinase regulator activity, receptor ligand activity, etc.The analysis of KEGG signaling pathway showed that the obvious pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis may involve IL-17 signaling pathway, TNF signal pathway, HIF-1signalpathway, Toll-like receptor signal pathway, etc.Conclusion:The potential mechanism of <italic>hindu datura</italic> for the treatment of rheumatoid arthritis is to exert anti-inflammatory, analgesic and antioxidant effects, which involve a number of interactive signal pathways.…”
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First-Principles Investigation of Structural, Electronic, and Room Temperature Ferromagnetism in Si-Doped Monolayer BN by Ahemedin Abedea Ajaybu, Sintayehu Mekonnen Hailemariam

“…We performed spin-polarized density functional theory (DFT) to investigate the structural, electronic, and magnetic properties of silicon- (Si-) doped monolayer boron nitride (BN). …”
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Highly efficient NIR-II photothermal therapy amplified ROS oxide breast tumor therapy by mesoporous gallium-enriched platinum nanomedicine by Yunfei Ying, Yonghui Su, Ao Wang, Tingting Li, Hongjun Zhuang, Siyaqi Li, Xiaolong Liu, Kecan Lin, Peiyuan Wang, Fuxing Zhang

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MODERN ARCHITECTURE BOARD INFORMATION AND CONTROL SYSTEMS OF HEAVY VEHICLES by A. Z. Asanov

“…The continuous increase in amounts of data processed on board of modern heavy trucks and complication of onboard systems and units functioning algorithms have led to the need to transfer the functions performed by a motorist to automatic robotized systems. …”
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Fluorescence Quenching of Graphene Quantum Dots from Orange Peel for Methyl Orange Detection by Weitao Li, Yang Liu, Xinglong Pang, Yuanhao Huang, Zeyun Dong, Qian Niu, Yuping Xiong, Shang Li, Shuai Li, Lei Wang, Huazhang Guo, Saisai Cui, Shenpeng Hu, Yuenan Li, Tiantian Cha, Liang Wang

“…Additionally, the GQDs possess high specific surface area, abundant surface functional groups, and excellent electronic conductivity, which contribute to their effective fluorescence quenching performance. …”
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Phylogeny and molecular evolution analysis of PIN-FORMED 1 in angiosperm. by Pengkai Wang, Tielong Cheng, Shuang Wu, Fangfang Zhao, Guangping Wang, Liming Yang, Mengzhu Lu, Jinhui Chen, Jisen Shi

“…PIN-FORMED 1 (PIN1) is an important secondary transporter and determines the direction of intercellular auxin flow. As PIN1 performs the conserved function of auxin transport, it is expected that the sequence and structure of PIN1 is conserved. …”
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Structural Characterization of Large Yellow Tea Polysaccharides and Its Inhibitory Effects on the Differentiation of 3T3-L1 Preadipocytes by Shan XU, Hai XIE, Minni LI, Yan MA, Huifang GE, Daxiang LI, Zhongwen XIE, Hongyan WANG

“…The polysaccharides were extracted from Huoshan large-leaf yellow tea, which structural characteristics including purity, molecular weight, monosaccharide composition, functional groups and glycosidic bond types were characterized by high performance gel permeation chromatography (HPGPC), ion chromatography (IC), gas chromatography-mass spectrometry (GC-MS), fourier transform infrared spectrometer (FTIR), and scanning electron microscope (SEM). …”
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Combining Acmella oleracea and Boswellia serrata extracts: a novel pharmacological approach in inflammatory vestibulodynia by Antimo Fusco, Michela Perrone, Federica Ricciardi, Andrea Maria Morace, Roozbe Bonsale, Milena Melake Teweldemedhin, Emanuele Di Martino, Rebecca Limongelli, Alfonso Papa, Sabatino Maione, Francesca Guida, Livio Luongo

“…Additionally, biochemical and functional evaluations were performed to measure spinal microgliosis and neuronal overexcitation. …”
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Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease by Bérengère Ballion, Marie-Laure Bonnet, Sébastien Brot, Afsaneh Gaillard

“…Conclusions Our findings indicate that grafted mDA neurons exhibit dopaminergic-like functional properties, including intrinsic membrane potential oscillations leading to regular firing patterns. …”
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Exploring Atypical Origins of Trismus: Surgical Solutions for Rare Pathologies—Insights from Rare Clinical Cases by Ioanna Kalaitsidou, Mathieu Gass, Dimitris Tatsis, Sherin Khalil, Christian Schedeit, Simon David Marjanowski, Sarah Wiegner, Benoît Schaller

“…<b>Background</b>: Trismus, or restricted mouth opening, can present significant challenges in oral and maxillofacial surgery and trigger substantial functional and psychosocial disabilities. Intra-articular causes, such as temporomandibular joint ankylosis and arthritis, are thoroughly described; however, extra-articular pathologies like neoplastic, traumatic, infectious, and fibrotic conditions of adjacent soft and hard tissues are less frequently reported and present distinct diagnostic complexities and therapeutic hurdles. …”
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