Human dental follicle stem cell-derived exosomes reduce root resorption by inhibiting periodontal ligament cell pyroptosis by Xinyi Li, Xinyang Liu, Jianing Zhou, Ping Zhang, Song Chen, Ding Bai

“…Results Exosomes released by force-stimulated DFSCs (Force-Exos) inhibited NOD-like receptor 3 (NLRP3)-mediated PDLC pyroptosis, which impacted M1 macrophage activation and osteoclast formation. …”
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Optimizing extraction of microbial DNA from urine: Advancing urinary microbiome research in bladder cancer by Chuang-Ming Zheng, Ho Won Kang, Seongmin Moon, Young Joon Byun, Won Tae Kim, Yung Hyun Choi, Sung-Kwon Moon, Xuan-Mei Piao, Seok Joong Yun

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Challenges issues and future recommendations of deep learning techniques for SARS-CoV-2 detection utilising X-ray and CT images: a comprehensive review by Md Shofiqul Islam, Fahmid Al Farid, F. M. Javed Mehedi Shamrat, Md Nahidul Islam, Mamunur Rashid, Bifta Sama Bari, Junaidi Abdullah, Muhammad Nazrul Islam, Md Akhtaruzzaman, Muhammad Nomani Kabir, Sarina Mansor, Hezerul Abdul Karim

“…Current diagnostic methods heavily rely on imaging techniques like CT scans and X-rays, but identifying SARS-CoV-2 in these images proves to be challenging and time-consuming. …”
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Comprehensive analysis of prognosis and drug sensitivity of programmed cell death pattern-related genes in gastric cancer patients by Huiheng Qu, Peng Zhou, Zhihui Yang, Hao Wang, Kaiyuan Deng, Nan Wang, Yuyang Li, Yupeng Zhao, Yigang Chen, Qian Yang, Jiazeng Xia

“…The performance of this model, tumor molecular subtypes, and the tumor microenvironment were assessed. …”
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Modulator-refractory cystic fibrosis: Defining the scope and challenges of an emerging at-risk population by Lindsay Somerville, Larry Borish, Imre Noth, Dana Albon

“…Highly effective modulator therapies (HEMT) improve the lives of many people with cystic fibrosis (PwCF) by correcting the structure and function of the defective CFTR channel at the molecular level. …”
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Comparison of clinical nasal endoscopy, optical biopsy, and artificial intelligence in early diagnosis and treatment planning in laryngeal cancer: a prospective observational study by Ruifang Hu, Xianping Liu, Yong Zhang, Clement Arthur, Dongguang Qin

“…Prompt diagnosis is crucial to improving survival and function. Direct laryngoscopy and imaging modalities are conventional diagnostic methods. …”
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Vagus nerve stimulation: a promising strategy to combat pyroptosis and inflammation in traumatic brain injury through the OX-A/NLRP3/caspase-1/GSDMD signaling pathway by Junwei Kang, Binkai Ren, Jia Wang, Yunliang Tang, Xiaoyang Dong

“…Results The findings revealed that VNS significantly enhanced neurological function, as indicated by lower mNSS scores and improved performance in the MWM test, suggesting a marked recovery in TBI-affected rats. …”
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The Influence of the COVID-19 Pandemic in NK Cell Subpopulations from CML Patients Enrolled in the Argentina Stop Trial by María Belén Sanchez, Bianca Vasconcelos Cordoba, Carolina Pavlovsky, Beatriz Moiraghi, Ana Ines Varela, Isabel Giere, Mariana Juni, Nicolas Flaibani, José Mordoh, Julio Cesar Sanchez Avalos, Estrella Mariel Levy, Michele Bianchini

“…NK cells from AST II patients demonstrated higher overall functionality and more memory-like subpopulations, characterized mainly by the expression of CD57, NKG2C, NKp30 and NKp46 receptors among CD56^dim NK cells, also with enhanced functional performance. …”
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Exploring ribosome biogenesis in lung adenocarcinoma to advance prognostic methods and immunotherapy strategies by Zipei Song, Yuheng Wang, Miaolin Zhu, Pengpeng Zhang, Zhihua Li, Xin Geng, Xincen Cao, Jianan Zheng, Jianwei Tang, Liang Chen

“…Immunohistochemistry was utilized to validate the expression levels of immune markers in the high- and low- RBS groups, and in vitro experiments were performed to validate the functional role of the pivotal gene KIF23 in the progression of LUAD. …”
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Paper and cardboard as sustainable materials by Jerzy F. Latka

“…The assessment of the environmental performance of cardboard as a building material is based on the following environmental categories proposed by M. …”
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Designing accessible and independent living spaces for visually impaired individuals: a barrier-free approach to interior design by Anushka Patil, Smruti Raghani

“…By integrating sensory elements like contrasting textures, lighting, and acoustic treatments, the project aims to foster spatial awareness, safety, and autonomy. …”
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Lactic Microbiota and Metabolites in Raw Cow’s Milk: Implications for Consumer Health by María Carmen Sánchez, Eduardo Soria, Arancha Llama-Palacios, Franco Almirón, Alberto Valdés, Alejandro Cifuentes, Marta Hernández, María José Ciudad, Luis Collado

“…Feeding regimen and geographical location influence microbial composition and metabolite abundance, while thermal stability was linked to specific metabolites like oleamide and pyridoxal. These findings suggest that microbiota-derived metabolites can enhance the nutritional and functional value of milk. …”
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Proteomic profiling identifies a stromal TGF-β1/podoplanin axis as a driver of colorectal cancer progression by Silvia Di Agostino, Davide La Padula, Vittoria Rago, Caterina Gabriele, Francesco Conforti, Elio Aprigliano, Lidia Urlandini, Elvira Parrotta, Danilo Lofaro, Francesca Vescio, Andrea Sacconi, Valeria Cernaro, Giuseppe Currò, Angela Alibrandi, Girolamo Ranieri, Valeria Zuccalà, Antonio Ieni, Marco Gaspari, Giovanni Cuda, Michele Ammendola, Vittorio Abbonante

“…Stromal cells pre-conditioned with M2-like macrophages upregulated PDPN and more effectively supported the growth of three colon adenocarcinoma cell lines. …”
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Medical Conditions in Former Professional American-Style Football Players Are Associated With Self-Reported Clinical Features of Traumatic Encephalopathy Syndrome by Rachel Grashow, Shawn R. Eagle, Douglas P. Terry, Heather DiGregorio, Aaron L. Baggish, Marc G. Weisskopf, Anthony Kontos, David O. Okonkwo, Ross Zafonte

“…., difficulties with memory, executive function) or neurobehavioral dysregulation (ND; e.g., explosiveness, rage, and mood lability) be present and not fully accounted for by other health disorders. …”
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Inhibition of histone deacetylases 3 attenuates imiquimod-induced psoriatic dermatitis via targeting cGAS-STING signaling in keratinocytes by Chong Zeng, Xiujuan Wen, Zibo Wei, Xinhuai Dong

“…However, its precise expression profile and functional contribution to psoriasis pathogenesis remain poorly defined. …”
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IMITATION OF STANDARD VOLUMETRIC ACTIVITY METAL SAMPLES by A. I. Zhukouski, A. O. Nichyparchuk, A. A. Khrutchinsky, S. A. Kutsen

“…Response functions or instrumental spectra of such spectrometer to radionuclides like 137Cs, 134Cs, 152Eu, 154Eu, 60Co, 54Mn, 232Th, 226Ra, 65Zn, 125Sb+125mTe, 106Ru+106Rh, 94Nb, 110mAg, 233U, 234U, 235U and 238U are required for calibration in a given measurement geometry. …”
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Effect of folic acid diet on the behavior of female mice and ultrasonic vocalization of their F1 offspring by Vineet Kumar Mourya, Sneha Tiwari, Nisha, Vijay Paramanik

“…Folic acid (FA) is an essential B vitamin that plays a pivotal in various physiological processes, including neural tube defects, brain functions, neurotransmitter synthesis, and cognition. …”
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MiR-181a-driven downregulation of cholesterol biosynthesis through SREBP2 inhibition suppresses uveal melanoma metastasis by Rui Wang, Claudia Gilbert, Houda Tahiri, Chun Yang, Solange Landreville, Pierre Hardy

“…Methods we investigated the effects of miR-181a on UM metastasis using multiple UM cell lines and a suprachoroidal injection mouse model. Functional assays, including migration, invasion, and cancer stem-like cell (CSC) formation, were performed. …”
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Structure-guided screening identified bioactive phytoconstituents Hernandonine and Anolobine as potential inhibitors of dual specificity protein kinase CLK1 by Sumaiya Khan, Arunabh Choudhury, Taj Mohammad, Anas Shamsi, Md Imtaiyaz Hassan, Asimul Islam

“…Currently, there are several small molecular CLK1 inhibitors, but problems like drug resistance and side effects still exist. …”
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Uncovering active ingredients and mechanisms of Pholiota adiposa in the treatment of Alzheimer’s disease based on network pharmacology and bioinformatics by Ma Xiaoying, Huo Zhiming, Shi Mingwen, Wang Hong, Yang Tao, Xiao Jun, Gong Na

“…We constructed a network of AD-relevant target proteins using databases like TCMSP, CTD, and GeneCards, and performed gene enrichment and functional analysis with DAVID, GO, and KEGG via Hiplot. …”
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