Constructing a research model for liver regeneration by using hepatocyte-like organoid derived from human pluripotent stem cells by WANG Chenxi, YANG Shuchun, JIA Yuyan, HUANG Yue

“…Conclusions A HLO-based hPSCs-derived human liver regeneration model is successfully constructed, which can be used for gene function studies during liver regeneration.…”
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Prototype of a Multimodal and Multichannel Electro-Physiological and General-Purpose Signal Capture System: Evaluation in Sleep-Research-like Scenario by Pablo Cevallos-Larrea, Leimer Guambaña-Calle, Danilo Andrés Molina-Vidal, Mathews Castillo-Guerrero, Aluizio d’Affonsêca Netto, Carlos Julio Tierra-Criollo

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Natural killer cells adopt an activated and decidual-like phenotype after autologous hematopoietic stem cell transplantation in children with cancer by Gabirel Astarloa-Pando, Diego Polanco-Alonso, Víctor Sandá, Ane Orrantia, Ainhoa Amarilla-Irusta, Silvia Pérez-Fernández, Raquel Pérez-Garay, Arrate Sevilla, Ainara Lopez-Pardo, Aritz Tijero, José J. Úriz, Mercedes Rey, Itziar Astigarraga, Bárbara Manzanares-Martin, Aitor Zarandona-Garai, Naiara G. Bediaga, Laura Amo, Olatz Zenarruzabeitia, Francisco Borrego

“…Abstract Background Natural killer (NK) cells are among the first immune cell populations to recover after autologous hematopoietic stem cell transplantation (autoHSCT ), yet their dynamic function in pediatric patients remains understudied. …”
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Diversity of Collagen Proteins and Their Biomedical Applications in Drug Delivery by Kuiming Wang, Rui Cao, Huijun Dong

“…As our understanding of the structure and function of collagen from different biological sources deepens, more new collagen materials and carriers with outstanding performance will continue to emerge and promote the application of collagen in the field of drug delivery.…”
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Biallelic Mutations in the Otogelin‐Like Gene (OTOGL) Associated With Congenital Non‐Syndromic Sensorineural Hearing Loss in a Chinese Family by Xiang Dai, Jun Li, Xijiang Hu, Wenqian Cai

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The HRAS-binding C2 domain of PLCη2 suppresses tumor‐like synoviocytes and experimental arthritis in rheumatoid arthritis by Hyun Min Jeon, Hae Sook Noh, Min-Gyu Jeon, Jin-Ho Park, Young-Sun Lee, Gyunghwa Seo, Yun-Hong Cheon, Mingyo Kim, Myung-Kwan Han, Jae-Yong Park, Sang-Il Lee

“…However, the roles of C2 domains in regulating the functions of RA FLSs remain unclear. Here we performed functional C2 domainomics with 144 C2 domain-containing viral vectors and identified the C2 domain of PLCη2 as a key regulator of RA FLSs. …”
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Robust Predictive Functional Control for Quadrotor Flight Systems by Kai Masuda, Kenji Uchiyama

“…However, PFC does not require solving a quadratic programming problem for every control loop like MPC. This feature enables PFC to be implemented in small-scale systems such as actuators, where embedding a high-performance computer is difficult. …”
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Creation of Functional Viruses from Non-Functional cDNA Clones Obtained from an RNA Virus Population by the Use of Ancestral Reconstruction. by Ulrik Fahnøe, Anders Gorm Pedersen, Carolin Dräger, Richard J Orton, Sandra Blome, Dirk Höper, Martin Beer, Thomas Bruun Rasmussen

“…RNA viruses have the highest known mutation rates. Consequently it is likely that a high proportion of individual RNA virus genomes, isolated from an infected host, will contain lethal mutations and be non-functional. …”
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Optimization of non-smooth functions via differentiable surrogates. by Shikun Chen, Zebin Huang, Wenlong Zheng

“…While data-driven models like gradient boosting and random forests excel at prediction tasks, they often lack mathematical regularity, being non-differentiable or even discontinuous. …”
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Water Market Functionality: Evidence From the Australian Experience by Maruge Zhao, Tiho Ancev, R. Willem Vervoort

“…Our findings show that the price mechanism in the water market functions as intended, as the water prices signal the level of scarcity and reflect value that can be derived from water resources. …”
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Working Memory as the Focus of the Bilingual Effect in Executive Functions by Jiejia Chen, Zitong Li, Zhiheng Xiong, Guangyuan Liu

“…The results showed that, after controlling for variables like intelligence, socioeconomic status, and age, bilingualism significantly predicted performance in both auditory and visual working memory tasks, explaining 34% and 19% of the variance, respectively. …”
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Variable power functional dilution adjustment of spot urine by Thomas Clemens Carmine

“…This study introduces a novel variable power functional creatinine correction method (V-PFCRC) to normalize analytes to 1 g/L CRN by utilizing uncorrected analyte levels and two analyte-specific coefficients, c and d. …”
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Tirzepatide Affect Sexual Function in Women: Case Report by Ghada Farouk Mohammed, Mohammed Saleh Al-Dhubaibi, Saleh Salem Bahaj, Rana Magdy Mohammed

“…Aims: The purpose of this report was to present a case study of an obese female patient who received tirzepatide treatment for sexual dysfunction. Methods: We performed an extensive clinical evaluation, which included the Female Sexual Function Index (FSFI). …”
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Evaluation of voiding dysfunctions in children with chronic functional constipation by Erhun Kasirga, Ipek Akil, Ozge Yilmaz, Muzaffer Polat, Salih Gözmen, Ayten Egemen

“… There are controversial results about the role of dysfunctional bowel emptying in disorders of the urinary tract like urinary tract infection (UTI), vesicoureteral reflux (VUR) and enuresis. …”
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Early detection of Alzheimer’s disease in structural and functional MRI by Rudrani Maity, Vellupillai Mariappan Raja Sankari, Umapathy Snekhalatha, Umapathy Snekhalatha, Shubashini Velu, Tahani Jaser Alahmadi, Zaid Ali Alhababi, Hend Khalid Alkahtani

“…ObjectivesTo implement state-of-the-art deep learning architectures such as Deep-Residual-U-Net and DeepLabV3+ for precise segmentation of hippocampus and ventricles, in functional magnetic resonance imaging (fMRI). Integrate VGG-16 with Random Forest (VGG-16-RF) and VGG-16 with Support Vector Machine (VGG-16-SVM) to enhance the binary classification accuracy of Alzheimer’s disease, comparing their performance against traditional classifiers.MethodOpenNeuro and Harvard’s Data verse provides Alzheimer’s coronal functional MRI data. …”
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A bibliometric review of functional ingredients and their efficacy in developing functional biscuits [version 3; peer review: 1 approved, 2 approved with reservations] by Kshama Vishwakarma, Varalakshmi Chandra Sekaran, Vidya Patwardhan, Asha Kamath

“…Introduction Numerous studies have concluded that the functional ingredients benefit human health. Similarly, present times have seen exponential growth in functional food in bakery product segments like breads and biscuits. …”
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Effect Of Handedness On Functional Organization Of Bimanual Isometric Handgrip by Nikolai Kolev, Ljudmila Halacheva

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The Double-Edged Sword of Vitamin A: Function and Toxicity by Paulina Grzeszczuk, Magdalena Jabłonowska

“…Materials and Methods: A thorough literature search was performed using PubMed and Google Scholar databases with the following keywords: "Vitamin A", "retinoids", "vitamin A deficiency", "hypervitaminosis A", "retinoic acid", "immune function", "vision", "skin health", "toxicity", and "wound healing". …”
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Preliminary Functional Analysis of the Gut Microbiome in Colic Horses by Pamela Thomson, Daniel Garrido, Rodrigo Santibáñez, Felipe Lara

“…PICRUSt2 was used to predict metabolic functions. Statistical analyses were performed with the Mann–Whitney U test from the Python scipy v1 package. …”
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Types and Functions of Repetition in the Works of Howard Phillips Lovecraft by N. S. Tatarincev

“…Conducting research is relevant for several reasons, like interest in the consideration of the functional aspects of the literary text as a whole, or to H. …”
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