The Impact of Acquired Hypothyroidism on the Growth and Metabolic Profiles of Pediatric Patients: A Retrospective Monocentric Study by Elena Malavolta, Ignazio Cammisa, Giulia Rotunno, Lucia Celeste Pane, Federica Arzilli, Giorgio Sodero, Donato Rigante, Clelia Cipolla

“…Pediatric patients with hypothyroidism, when left untreated or when thyroid hormone levels fail to normalize despite treatment, may exhibit various complications such as growth retardation, obesity, and hypercholesterolemia. …”
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The Jojosi Dongas: An interdisciplinary project to study the evolution of human behaviour and landscapes in open-air contexts by Manuel Will, Matthias Blessing, Gunther H.D. Möller, Lawrence Msimanga, Hanna Pehnert, Svenja Riedesel, Greg A. Botha, Christian Sommer

“…The remains left behind at such sites allow for unique archaeological insights into the spatial patterning of prehistoric behaviour. …”
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Alterations in the gut microbiome and metabolism with doxorubicin-induced heart failure severity by Qian Wang, Meihua Liu, Meihua Liu, Tianpei Liu, Tianpei Liu, Long Li, Chenyang Wang, Xiaolin Wang, Shuling Rong, Xuedong Zhou

“…At different times after injection, the cardiac function and histopathological analysis was conducted, the serum levels of creatine kinase (CK), CK-MB, lactic dehydrogenase, and cardiac troponin T were determined. 16S rRNA gene sequencing of feces and the nontargeted metabolomics analysis of serum were performed. …”
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Value of transoesophageal echocardiography-guided approach to electrical cardioversion of atrial fibrillation by O. S. Kalashnikovа

“…Correlation analysis showed association between thrombi in atrial appendages and age (r = 0,21; р < 0,03), obesity (r = 0,23; р < 0,02), NYHA functional class of heart failure (r = 0,29; p < 0,01), CHA2DS2 –VASc score (r = 0,19; p < 0,04), left atrial volume in diastole (r = 0,18; p < 0,05), inverse correlation was found between first diagnosed AF and atrial appendages thrombi (r = -0,25; p < 0,01). …”
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The contribution of modifiable risk factors to the formation of cardiovascular remodelling and vegetative balance in patients with essential hypertension by V. V. Syvolap, O. V. Vizir-Tronova

“…The addition of any single RF in patients with EH is associated with an increase in the size of left atrium, left ventricular myocardial mass index mainly due to thickening of the interventricular septum, diastolic dysfunction of the left ventricle. …”
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Atrial remodelling and dysfunction in hypertrophic cardiomyopathy: prognostic role and therapeutic target by Chiara Piazzai, Alessio Petrone, Andrea Stefanini, Flavio D’Ascenzi, Iacopo Olivotto, Iacopo Olivotto, Matteo Cameli

“…Recent studies have highlighted that left atrial (LA) remodelling—including dilation, fibrosis, and functional impairment—plays a key role in disease progression and prognosis, notably increasing the risk of atrial fibrillation (AF) and stroke.Material and methodsThis review article systematically examines published clinical, imaging, and interventional studies. …”
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Relationships between the activity of neurohormonal systems and intracardiac hemodynamics in patients with heart failure: focus on galectin-3 by V. I. Podzolkov, N. A. Dragomiretsksya, A. V. Kazadaeva, Yu. G. Beliaev, Anastasia V. Tolmacheva

“…Correlation analysis revealed significant feedback (r=-0,41, p&lt;0,05) between galectin-3 and left ventricular EF only in patients with preserved systolic function. …”
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Features of heart remodeling in patients with obstructive sleep apnea syndrome and its comorbid association with obesity in the context of the senilism concept by T. O. Brodovskaya, O. O. Grishchenko, I. F. Grishina, T. F. Peretolchina

“…Systolic function in both study groups was preserved however, a tendency to stress of adaptive remodeling mechanisms was revealed. …”
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EFFECT OF ANTIVIRAL THERAPY ON CARDIOHEMODYNAMIC INDICATORS IN PATIENTS WITH CHRONIC VIRAL HEPATITIS AND LIVER CIRRHOSIS by M. V. Chistyakova, A. V. Govorin, E. V. Radaeva

“…The improvement of systolic and diastolic function of the left ventricle (LV), decrease inLV myocardial mass (from 170 [225.5;213.5] to 159 [146;167] g; p&lt;0.001), and size of the left atrium (LA; from 37 [34;40] to 35.5 [33;38] mm; p&lt;0.001) were found in patients with CVH after AVT. …”
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HEART REMODELING IN OVERWEIGHT AND OBESITY WITH CARDIAC COMORBIDITIES by I. V. Logacheva, T. A. Ryazanova, V. R. Makarova, F. R. Avzalova, N. I. Maksimov

“…To assess structural geometric and functional disorders of the heart in males with coronary heart disease (CHD) comorbid with arterial hypertension (AH) and with visceral abdominal obesity, and to evaluate the grade of association of epicardial fat thickness (EFT) with cardiometabolic risk factors (RF).Material and methods. …”
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Comparison of peritoneal dialysis and hemodialysis on sleep and life quality in patients with refractory congestive heart failure by YIN Dong-yang, ZHANG Qing-yan, SUN Cheng, XU Peng-fei, SHAO Qiu-yuan, JIANG Chun-ming, ZHANG Miao

“…Objective To investigate the effect of peritoneal dialysis(PD)and hemodialysis(HD)on sleep and life quality in patients with refractory congestive heart failure(RCHF).Methods The clinical data and follow-up material of PD patients(31)or HD ones(17)in Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School from January 1,2010 to December 31,2017,were analyzed retrospectively.Clinical and laboratory examination data before and 6 months after dialysis,the MOS item short from health survey(SF-36)results,and Pittsburgh sleep quality index( PSQI)were collected for analysis.Through self-contrast of the indices before and after treatment,effects of the two treatment ways on life quality in these patients were compared.Results After six months treatment,both PD and HD effectively improved NYHA classification and B-type natriuretic peptide levels(both P<0.01)with no significant difference between the two treatment ways(P>0.05).Neither PD nor HD significantly improved left ventricular ejection fraction after 6-month dialysis(P>0.05).Except hypnotic drugs and daytime dysfunction,other sleep quality indices were improved significantly the HD patients(P<0.05).In the PD patients,except hypnotic drugs,other 6 sleep quality indices were improved significantly(P<0.05).Total PSQI scores were increased for both HD and PD ways(P<0.05)with no difference between HD and PD(P>0.05).Other 7 life quality indices except emotional function were significantly improved in the HD patients(P<0.01),while all the eight life quality indices were improved in the PD patients(P<0.01).After treatment of 6 months,except physical function other life quality indices for the PD patients were better than those for the HD patients(all P<0.05).Logistic regression analysis showed that PD was associated with better emotional function and physical function than HD(P<0.05).Conclusions Both PD and HD can both improve clinical symptoms and sleep quality in RCHF patients as assessed by NYHA classification and B-type natriuretic peptide levels.However,improvement of life quality for PD was better than that for HD.…”
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Laboratory and instrumental parameters of patients with ischemic heart disease in dependence of gallbladder condition: correlational analysis by L. M. Strilchuk, I. B. Zhakun, Z. M. Kit, O. O. Sorokopud, M. O. Kondratyuk

“…Established reliable correlations of both type and degree of GB damage with RCA stenosis grade and other clinical, laboratory and instrumental parameters (prothrombin time, fibrinogen and ALT levels, hypertrophy and diastolic dysfunction of the left ventricle etc.) are associated with a tendency to hypercoagulability and thrombi formation, hyperkaliemia, and define both morphological and functional interrelations of GB disorders with coronary arteries anomalies. …”
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Clinical portrait of a patient with acute coronary syndrome and type 2 diabetes mellitus: a novel strategy for the diagnosis, prognosis and treatment by M.I. Shved, I.O. Yastremska, L.V. Levytska, V.Yu. Kuchmiy, O.A. Prokopovych, Ya.M. Kitsak, R.M. Liakhovych

“…Such individuals have more pronounced manifestations of necrosis-resorption syndrome, a significant increase in left ventricular myocardial mass and volume due to an increase in diastolic and systolic dimensions, which suggests hypertrophy and cardiac remodeling with impaired systolic function (ejection fraction of less than 50 %) and impaired diastolic function; the latter is considered an impairment of relaxation processes. …”
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Lymphoproliferative disorders and renal dysfunction: a case of CLL-related AKI by Akhil Tomy, Aswathi Balakrishnan, Siva Shrikanth, Cristoss Gregory, Maria Elizabeth John, Tanushree Dewan

“…A blood film confirmed CLL, but there was no evidence of haemolysis. Renal function was significantly impaired, with creatinine of 296 µmol/L and an eGFR of 18 mL/min/1.73 m2. …”
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ANTIHYPERTENSIVE THERAPY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: ADVANTAGES OF CALCIUM ANTAGONISTS by T. V. Adasheva, I. V. Fedorova, V. S. Zadionchenko, M. V. Macievich, V. V. Lee, S. V. Pavlov

“…Reduction of diastolic dysfunction of left and right ventricles was revealed. Therapy was safe in terms of respiratory function. …”
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MODERN METHODS OF INTRACARDIAC HEMODYNAMICS AND CARDIAC DEFORMABILITY ASSESSMENT IN PREGNANT WOMEN WITH DILATION CARDIOMYOPATHY SYNDROME by D. A. Doroshenko, A. R. Zubarev, O. V. Lapochkina, O. V. Konysheva, E. E. Tyulkina, N. A. Volov

“…Controls consisted of 30 pregnant women with normal systolic and pumping heart function, and non-changed geometry of the left ventricle (LV). …”
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Central hemodynamics in elderly patients with arterial hypertension treated with perindopril A/indapamide (Noliprel A/forte) and lowintensity laser therapy by T. V. Filippova, G. G. Efremushkin, Yu. A. Melnikova, A. A. Perfiliev, V. V. Shadrin

“…At baseline, AH patients demonstrated relatively normal systolic myocardial function combined with diastolic left and right ventricular (LV, RV) dysfunction and increased ventricular transverse sizes. …”
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DIASTOLIC DYSFUNCTION OF THE RIGHT VENTRICLE IN CORONARY HEART DISEASE PATIENTS by O. G. Arkhipov, A. N. Sumin

“…Patients  were selected to 2 groups:  with saved diastolic RV function (n=478) and with RVDD (n=199). All participants  underwent echocardiography with diastolic function assessment of the left ventricle (LV) and RV in impulse-wave dopplerometry  of atrioventricular flows, spectral  tissue Doppler of the mitral and tricuspid anuli, and color-M-modal scan.Results. …”
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Effectiveness of pre-surgery ivabradine treatment in patients with manifested thyrotoxicosis by L. V. Shpak, Yu. A. Volkova

“…The latter manifested in reduced cardiac ejection volume, left ventricular contractility power, and pulse rate velocity, combined with increased total peripheral vascular resistance and unchanged BP. …”
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Two strategies for arterial hypertension treatment in patients with secondary chronic pyelonephritis by M. E. Statsenko, M. V. Derevyanchenko

“…The combinations “enalapril + indapamide” and “enalapril + nifedipine SR” had similar effects in terms of BP lowering, MAU reduction, and improvement of proximal renal tubular function. In both groups, there was a decrease in the number of patients with circadian BP rhythm disturbances, adverse left ventricular remodelling types, or diastolic dysfunction. …”
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