Landscape of extracellular small RNA and identification of biomarkers in multiple human cancers by Shoubin Zhan, Ye Xu, Botao Li, Peng Ge, Chunwu Zhang, Shengkai Zhou, Tingting Yang, Gaoli Liang, Ling Ji, Xiangbin Kong, Ping Yang, Xi Chen, Chen-Yu Zhang, Han Shen, Xu Luo, Zhen Zhou, Yanbo Wang

“…Summary: Extracellular RNAs (exRNAs) in biofluids, sourced from diverse tissues, exhibit various biological functions and diagnostic potential. Small non-coding RNAs, such as rsRNAs and tsRNAs, are abundant in tissues and likely secreted into biofluids, contributing to exRNA profiles. …”
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Applications of Artificial Intelligence in Biotech Drug Discovery and Product Development by Yuan‐Tao Liu, Le‐Le Zhang, Zi‐Ying Jiang, Xian‐Shu Tian, Peng‐Lin Li, Pei‐Huang Wu, Wen‐Ting Du, Bo‐Yu Yuan, Chu Xie, Guo‐Long Bu, Lan‐Yi Zhong, Yan‐Lin Yang, Ting Li, Mu‐Sheng Zeng, Cong Sun

“…By consolidating cross‐domain advances, this review provides a roadmap for leveraging machine learning to overcome current biopharmaceutical bottlenecks and accelerate next‐generation therapeutic innovation.…”
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Identifying and Validating Indicators of Ritualism in the Iranian Higher Education System: A Mixed-Methods Study by Seyed Hedayat Davarpanah, Reza Hoveida, Mostafa Bagherian Far

“…Neglecting its indicators in the core functions of the university—teaching, research, and services—can lead to institutions that lack quality and fail to make a significant impact on society, both formally and functionally.  …”
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Treatment of the Cirrhotic Patients Considering Portal Hypertension Severity Degree and Comorbid Syntropic Extrahepatic Lesions, their Complications: Modified Algorithm, its Effect... by Ferko M.

“…Information on mortality due to the liver cirrhosis is ambiguous – from 8 to 80 per 100 thousand population. It was learned that liver cirrhosis is not limited by the injury of hepatobiliary system, but also extends to other organs and systems that can be considered as cirrhotic disease of the whole organism with involvement into the pathological process of various organs and systems of the human body, interpreted as syntropic comorbid lesions, which in most of the cases cause temporary, and in the future – sustainable abnormal function, disability, often – death of the patient. …”
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Path and Practice of Gap Management in National Parks: A Comparison Between China and the US and Inspirations Therefrom by Yun MA, Siyuan HE

“…In contrast, the US predominantly employs a “gap closing” strategy, seeking to resolve the issues of land ownership and functional discrepancy through legal tools and land regulation. …”
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Multiscale metal-based nanocomposites for bone and joint disease therapies by Yuwen Wang, Hasnain Jan, Zheng Zhong, Liangbin Zhou, Kexin Teng, Ye Chen, Jiankun Xu, Denghui Xie, Dexin Chen, Jiake Xu, Ling Qin, Rocky S. Tuan, Zhong Alan Li

“…Bone and joint diseases are debilitating conditions that can result in significant functional impairment or even permanent disability. …”
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Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024 by --- Various Authors

“…Masnata (Cagliari, Italy) ABS 24. AN UNSUPERVISED LEARNING TOOL FOR STEM CELL BURDEN ASSESSMENT IN THE PRETERM KIDNEY • M. …”
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Особливості архітектурно-планувальної організації центрів розвитку молоді by Olena Troshkina, Alona Lupina

“…The scientific novelty of the research lies in the fact that: - the features of the formation of the architecture of modern leisure institutions for young people were revealed, obtained as a result of the analysis and study of the existing domestic practice of design and construction of similar buildings in the modern world; - the functional blocks of the modern youth development center were identified, which form a positive psychological microclimate, which reflects the specifics of the perception and interaction of a young person with the architectural space; - it has been proven that the main point in the design of modern youth centers is the formation of a motivational environment and focusing on the ability to use gadgets and multimedia devices in learning conditions and further prospects for self-realization in the field of technogenic communication. …”
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FEATURES OF THE USE OF MOBILE COMMUNICATION IN THE STUDENT ENVIRONMENT / ОСОБЕННОСТИ ИСПОЛЬЗОВАНИЯ МОБИЛЬНОЙ СВЯЗИ В СТУДЕНЧЕСКОЙ СРЕДЕ... by SHARIKOV ALEXANDER V . / ШАРИКОВ А.В., EROFEEV SERGEI V. / ЕРОФЕЕВ С.В.

“…The use of mobile communication by Russian students is characterized by wide functionality—the total number of identified functions amounted to more than 20, most of which are related to the Internet. …”
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A novel ecological risk assessment method of potentially toxic elements based on soil nematode communities by Xiujuan Yang, Li Cao, Bijun Cheng, Huirong Duan, Zixuan Fu, Xiaofang Xu, Qianying Xiang, Shuhan Wang, Xiaoqing Yan, Zhihong Zhang, Hongmei Zhang

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Handwritten Words Image Character Extraction Adaptive Algorithm Based on the Multi-branch Structure by GUO Xiaojing, ZHAO Xiaoyuan, ZOU Songlin

“…The improved model comprises four functional components. The innovation of this study lies in several aspects. …”
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Mental Health in the Age of Hyperconnectivity: A Crisis Hidden in Plain Sight by Sitara Ejaz, Hafiz Muhammad Haseeb Khaliq

“…Exposure to screens before bedtime reduces melatonin production by 55% (±20.1%), according to sleep specialists, which causes sleep disturbances that negatively affect both mental function and mood patterns 9.  The mental health challenges faced by young people exist far above other population groups. …”
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Antibiotic use for common illnesses in children living with disability: a multi-country study across 42 low- and middle-income countriesResearch in context by Shengyue Qiu, Mingli Xu, Yuanyang Wu, Chaojie Liu, Xiying Li, Xinyi Yang, Haohai Xia, Ruonan Wang, Zishu Ma, Fanqian Meng, Xinping Zhang, Gordon Liu, Hannah Kuper, Shanquan Chen, Lianping Yang

“…Disability status was assessed using the Washington Group-Child Functioning Module. Reported antibiotic use was measured by whether children with disabilities received antibiotic treatment for common childhood illnesses. …”
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Distinct subnetworks of the mouse anterior thalamic nuclei by Houri Hintiryan, Mitchell Rudd, Sumit Nanda, Adriana E. Gutierrez, Darrick Lo, Tyler Boesen, Luis Garcia, Jiandong Sun, Christian Estrada, Hyun-Seung Mun, Seita Yamashita, Yeji E. Han, Ian Bowman, Lin Gou, Chunru Cao, Jennifer Gonzalez, Keivan Moradi, Qiuying Zhao, Inga Yenokian, Aishwarya Dev, Brian Zingg, Hanpeng Xu, Qing Xue, Muye Zhu, Lijuan Liu, Xin Chen, Zhixi Yun, Hanchuan Peng, Nicholas N. Foster, Hong-Wei Dong

“…Structurally, the ATN facilitate communication among the neocortex, hippocampus, amygdala, and hypothalamus. Functionally, they play pivotal roles in learning, memory, spatial navigation, and goal-directed behaviors. …”
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Interventions to improve mental health and well-being in care-experienced children and young people aged less than 25: the CHIMES systematic review by Rhiannon Evans, Sarah MacDonald, Robert Trubey, Jane Noyes, Michael Robling, Simone Willis, Soo Vinnicombe, Maria Boffey, Charlotte Wooders, Asmaa El-Banna, GJ Melendez-Torres

“…Limitations The review was limited by a paucity of theory and economic evaluations, so it is unclear how interventions might function or their potential cost-effectiveness. Interventions were insufficiently described, making it challenging to map the evidence base. …”
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Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn’s disease by Lisa Budzinski, Gi-Ung Kang, René Riedel, Toni Sempert, Leonie Lietz, René Maier, Janine Büttner, Bettina Bochow, Marcell T. Tordai, Aayushi Shah, Amro Abbas, Tanisha Momtaz, Jannike L. Krause, Robin Kempkens, Katrin Lehman, Gitta A. Heinz, Anne E. Benken, Stefanie Bartsch, Kathleen Necke, Ute Hoffmann, Mir-Farzin Mashreghi, Robert Biesen, Tilmann Kallinich, Tobias Alexander, Bosse Jessen, Carl Weidinger, Britta Siegmund, Andreas Radbruch, Anja Schirbel, Benjamin Moser, Hyun-Dong Chang

“…The data were analyzed by machine-learning to assess disease-specific marker patterns in the microbiota phenotype. mMFC captured detailed characteristics of CD microbiota and identified patterns to classify CD patients. …”
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Supporting African communities to increase resilience and mental health of kids with developmental disabilities and their caregivers using the World Health Organization’s Caregiver... by Melissa Washington-Nortey, Vibian Angwenyi, Mekdes Demissie, Eva Mwangome, Tigist Eshetu, Hanna Negussie, Kimberley Goldsmith, Andrew Healey, Merga Feyasa, Girmay Medhin, Amanuel Belay, Temesgen Azmeraw, Medhanit Getachew, Rahel Birhane, Carophine Nasambu, Tsegereda Haile Kifle, Angela Kairu, Beatrice Mkubwa, Fikirte Girma, Rehana Abdurahman, Ruth Tsigebrhan, Liya Tesfaye, Leonard Mbonani, Nadine Seward, Tony Charman, Andrew Pickles, Erica Salomone, Chiara Servili, Edwine Barasa, Charles R. Newton, Charlotte Hanlon, Amina Abubakar, Rosa A. Hoekstra

“…Pilot study findings of the World Health Organization’s Caregiver Skills Training (WHO CST) intervention, which equips caregivers with strategies to facilitate learning and adaptive behaviours in children with DD, are promising but evidence from an appropriately powered trial delivered by non-specialist facilitators is lacking. …”
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Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading by Xiaoli Liu, Huijin Wang, Xi Tian, Yingqi Luo, Minmin Ma, Zilong Zheng, Yaping Wang, Shi Feng, Qiushi Wang, Zhuo Xu, Wen Yao, Siqiang Ren

“…Together, our study highlights an important function of microglia Kv1.3 in the promotion of Aβ propagation in the context of depression-exacerbating AD pathology.…”
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Rough-and-Refine Model for Scene Graph Generation by Li Junliang, Lv Shirong, Li Wei

“…This is particularly crucial in the context of the long-tail distribution problem present in the dataset, as it demonstrates the model's learning capability across all predicate categories. …”
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Unlocking data: Decision-maker perspectives on cross-sectoral data sharing and linkage as part of a whole-systems approach to public health policy and practice by Emily Tweed, Kristina Cimova, Peter Craig, Mirjam Allik, Denise Brown, Mhairi Campbell, David Henderson, Charlie Mayor, Petra Meier, Nick Watson

“…This covered three key overarching themes: differing understandings of evidence; diverse functions of evidence; and factors affecting use (such as technical, political and institutional, workforce and governance). …”
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