Motor Skill Acquisition Promotes Human Brain Myelin Plasticity by Bimal Lakhani, Michael R. Borich, Jacob N. Jackson, Katie P. Wadden, Sue Peters, Anica Villamayor, Alex L. MacKay, Irene M. Vavasour, Alexander Rauscher, Lara A. Boyd

“…However, in humans it is not known whether specific features of white matter relate to motor skill acquisition or if these structural changes are associated to functional network connectivity. Myelin can be objectively quantified in vivo and used to index specific experience-dependent change. …”
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Role of the NO-GC/cGMP signaling pathway in platelet biomechanics by Aylin Balmes, Johanna G. Rodríguez, Jan Seifert, Daniel Pinto-Quintero, Akif A. Khawaja, Marta Boffito, Maike Frye, Andreas Friebe, Michael Emerson, Francesca Seta, Robert Feil, Susanne Feil, Tilman E. Schäffer

“…Our results corroborate a functional role of the NO-GC/cGMP pathway in platelet biomechanics, indicating that biomechanical properties such as stiffness or shape could be used as novel biomarkers in clinical research.…”
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Artificial synapse‐based intelligent light‐controlled liquid crystal network actuators by Yuhang Song, Junyao Zhang, Zejun Sun, Haixia Liang, Tongrui Sun, Zhimin Lu, Shucong Li, Yuxing Yao, Xiaoguang Wang, Yang Xu, Jia Huang

“…These AS‐LCNs can perform programmable intelligent sensing, learning, and memory within a wide wavelength range from 365 nm to 808 nm. …”
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Accelerometry and the Capacity–Performance Gap: Case Series Report in Upper-Extremity Motor Impairment Assessment Post-Stroke by Estevan M. Nieto, Edaena Lujan, Crystal A. Mendoza, Yazbel Arriaga, Cecilia Fierro, Tan Tran, Lin-Ching Chang, Alvaro N. Gurovich, Peter S. Lum, Shashwati Geed

“…This case series investigates whether traditional machine learning (ML) and convolutional neural network (CNN) models trained on wrist-worn accelerometry data collected in a laboratory setting can accurately predict real-world functional hand use in individuals with chronic stroke. …”
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Integrating multidimensional data analytics for precision diagnosis of chronic low back pain by Sam Vickery, Frederick Junker, Rebekka Döding, Daniel L. Belavy, Maia Angelova, Chandan Karmakar, Luis Becker, Nima Taheri, Matthias Pumberger, Sandra Reitmaier, Hendrik Schmidt

“…The dataset included questionnaire data, clinical and functional assessments, and spino-pelvic magnetic resonance imaging (MRI), encompassing a total of 144 parameters from 1,161 adults with (n = 512) and without cLBP (n = 649). …”
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Unraveling heterogeneity and treatment of asthma through integrating multi-omics data by Wei Zhang, Yu Zhang, Lifei Li, Rongchang Chen, Fei Shi, Fei Shi

“…We next discussed how integrated analysis of multi-omics data via machine learning can systematically characterize the molecular and biological profiles of genetic heterogeneity of asthma phenotype. …”
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A mixed methods pilot feasibility study of the unified protocol group psychotherapy for early bipolar disorder by Magnus Johan Engen, Siv Hege Lyngstad, Erlend Eikenæs, Jon Vøllestad, Margrethe Collier Høegh, Trine Vik Lagerberg, Trine Vik Lagerberg, Sofie Ragnhild Aminoff

“…Quantitative findings indicated significant improvements in affective lability, overall functioning, and well-being. Qualitative findings highlighted participants’ appreciation for the structured format and peer support from the group, which facilitated exploration of emotional experiences and skills practice. …”
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Neuropsychiatric disorders in Chinese pediatric tuberous sclerosis complex patients associated with drug-resistant epilepsy: A TAND checklist-based survey by Jie Fu, Qinrui Li, Genfu Zhang, Zhixian Yang, Jiong Qin

“…The study found that 66 % of participants exhibited varying degrees of intellectual disability, with the DRE group demonstrating significantly poorer performance in intelligence, behavior, neuropsychological, and learning skills compared to the seizure-free group. …”
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Fingerprint patterns of human brain activity reveal a dynamic mix of emotional responses during virtual intergroup encounters by Gloria Mendoza-Franco, Inga Jasinskaja-Lahti, Matthias B. Aulbach, Ville J. Harjunen, Anna Peltola, J. Niklas Ravaja, Matilde Tassinari, Saana Vainio, Iiro P. Jääskeläinen

“…In this study, we used machine learning to identify emotional brain patterns using functional magnetic resonance imaging. …”
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Chemical imaging delineates Aβ plaque polymorphism across the Alzheimer’s disease spectrum by Srinivas Koutarapu, Junyue Ge, Maciej Dulewicz, Meera Srikrishna, Alicja Szadziewska, Jack Wood, Kaj Blennow, Henrik Zetterberg, Wojciech Michno, Natalie S. Ryan, Tammaryn Lashley, Jeffrey N. Savas, Michael Schöll, Jörg Hanrieder

“…Understanding the association of polymorphic Aβ pathology with AD pathogenesis and progression is critical in light of emerging Aβ-targeting therapies. In this work, functional amyloid microscopy enhanced by deep learning was integrated with mass spectrometry imaging to delineate polymorphic plaques and to identify their associated Aβ make-up. …”
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A novel miR-4536-3p inhibition ameliorates Alzheimer’s disease by reducing Aβ accumulation and tau phosphorylation by Jiyun Choi, Dohee Kim, Haewon Jeong, Jinsu Hwang, Mahesh Ramalingam, Sujin Han, Hyong-Ho Cho, Byeong C. Kim, Han-Seong Jeong, Sujeong Jang

“…Apoptosis, neuronal markers, and signaling pathways were assessed through functional assays. Cognitive effects were evaluated via the Morris water maze. …”
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Rapid and cumulative adult plasticity in the mouse visual cortex by Hiroyuki Miyamoto, Emi Mazaki, Yuichi Makino, Qi Fang, Tomohito Hamada, Youichi Handa, Takao K. Hensch, Takao K. Hensch, Takao K. Hensch

“…The dual temporal characteristics of flash-evoked visual plasticity likely reflect multifaceted aspects of adult brain functionality, encompassing processes related to memory, learning, and neurological disorders. …”
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Nature-inspired hierarchical building materials with low CO2 emission and superior performance by Jinyang Jiang, Han Wang, Junlin Lin, Fengjuan Wang, Zhiyong Liu, Liguo Wang, Zongjin Li, Yali Li, Yunjian Li, Zeyu Lu

“…These properties are further investigated with machine learning force field molecular dynamics along with well-tempered metadynamics simulations, indicating that strong chemical bonding is generated at the atomic level between functional groups in the hydrogel and Ca ion released from cement hydration. …”
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Artificial intelligence enabled smart design and manufacturing of advanced materials: The endless Frontier in AI+ era by William Yi Wang, Suyang Zhang, Gaonan Li, Jiaqi Lu, Yong Ren, Xinchao Wang, Xingyu Gao, Yanjing Su, Haifeng Song, Jinshan Li

“…Our recent developed ProME platform together with its functions is introduced briefly. A case study of AI agent assistant welding is presented, which is consisted of the large language model, auto‐coding via AI agent, image processing, image mosaic, and machine learning for welding defect detection. …”
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A versatile framework for attitude tuning of beamlines at light source facilities by Peng-Cheng Li, Xiao-Xue Bi, Zhen Zhang, Xiao-Bao Deng, Chun Li, Li-Wen Wang, Gong-Fa Liu, Yi Zhang, Ai-Yu Zhou, Yu Liu

“…It supports flexible input/output ports, easy integration of diverse evaluation functions and free selection of optimization algorithms. …”
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Metaheuristic Optimization for Robust RSSD-Based UAV Localization with Position Uncertainty by Yuanyuan Zhang, Jiping Li, T. Aaron Gulliver, Huafeng Wu, Guangqian Xie, Xiaojun Mei, Jiangfeng Xian, Weijun Wang, Linian Liang

“…However, potential collisions and other issues can disrupt communication and hinder functionality in real-world applications. Therefore, accurate localization of UAVs is crucial. …”
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Mesenchymal stem cells and their extracellular vesicles: new therapies for cartilage repair by Hongwei Yang, Hongwei Yang, Haochen Yang, Qin Wang, Hanzhen Ji, Tianmei Qian, Tianmei Qian, Yusen Qiao, Junfeng Shi, Meng Cong

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Four individually identified paired dopamine neurons signal taste punishment in larval Drosophila by Denise Weber, Katrin Vogt, Anton Miroschnikow, Michael J Pankratz, Andreas S Thum

“…To understand how individual DANs contribute to these functions, we studied Drosophila larvae, which have only about 120 DANs. …”
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PIRO: A web-based search platform for pathology reports, leveraging large language models to generate discrete searchable insights by Scott Robertson, Venkata Koppireddy, Jeremy Cumbo, Hooman Rashidi, Samer Albahra

“…Built using FastAPI, Angular, and Apache Solr, PIRO supports both basic and advanced search functionalities, faceted filtering, and data extraction, while ensuring compliance with institutional privacy protocols. …”
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Health literacy of adolescents’ responses to a workshop focusing on food, nutrition, climate change and digital technology solutions in Oceania: a multi-site pilot study in Vanuatu... by Louisa R. Peralta, Rowena Forsyth, Nanise Lapi, Krestina L. Amon, Pierre Metsan, Guillaume Wattelez, Juliana Chen, Olivier Galy, Corinne Caillaud

“…Results School  A’s booklet responses showed that interactive health literacy responses were dominant (54%), followed by functional (34%) and critical learning activities (12%), whereas School B’s responses showed that functional health literacy responses were dominant (65%), followed by interactive (28%) and critical (5%). …”
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