The 7-Methylguanosine (m7G) methylation METTL1 acts as a potential biomarker of clear cell renal cell carcinoma progression by Yi Liu, Yanji Zhan, Jiao Liu, Zhengze Shen, Yudong Hu, Ling Zhong, Yuan Yu, Bin Tang, Jing Guo

“…Background: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cancer. 7-Methylguanosine (m7G), one of the most prevalent RNA modifications, has been reported to play an important role in ccRCC progression; however, the specific regulators of m7G modification that are involved in this function remain unclear. This study aimed to explore the correlation between regulators of m7G methylation and ccRCC progression using unsupervised machine learning methods.Methods: Transcriptome and clinical data of ccRCC were retrieved from The Cancer Genome Atlas (TCGA) database to identify differentially expressed m7G-related genes associated with the overall survival of patients with ccRCC. …”
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An optoelectrochemical synapse based on a single-component n-type mixed conductor by Yazhou Wang, Wentao Shan, Hanrui Li, Yizhou Zhong, Shofarul Wustoni, Johana Uribe, Tianrui Chang, Valentina E. Musteata, Tania Cecilia Hidalgo Castillo, Wan Yue, Haifeng Ling, Nazek El‐Atab, Sahika Inal

“…The resulting transistor active-matrix array is capable of adaptive sensing, memory, and pre-processing of visual information, demonstrating an efficient optoelectronic neuromorphic system with multi-task learning capability.…”
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Smartphone video-based early diagnosis of blepharospasm using dual cross-attention modeling enhanced by facial pose estimation by Shenyu Huang, Boyuan Yang, Xiaoling Huang, Huina Zhang, Dong Luo, Guanchao Tong, Yijie Wang, Yongqing Shao, Menglu Chen, Qi Gao, Juan Ye

“…Abstract Blepharospasm is a focal dystonia characterized by involuntary eyelid contractions that impair vision and social function. The subtle clinical signs of blepharospasm make early and accurate diagnosis difficult, delaying timely intervention. …”
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Longitudinal Analysis of Stroke Patients’ Brain Rhythms during an Intervention with a Brain-Computer Interface by Ruben I. Carino-Escobar, Paul Carrillo-Mora, Raquel Valdés-Cristerna, Marlene A. Rodriguez-Barragan, Claudia Hernandez-Arenas, Jimena Quinzaños-Fresnedo, Marlene A. Galicia-Alvarado, Jessica Cantillo-Negrete

“…Upper limb rehabilitation is particularly challenging since approximately 35% of patients recover significant hand function after 6 months of the stroke’s onset. Therefore, new therapies, especially those based on brain-computer interfaces (BCI) and robotic assistive devices, are currently under research. …”
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MOTIVATIONAL COMPONENT AS A SUCCESS TO ORGANIZE AN INDEPENDENT WORK OF STUDENTS AT THE DEPATMENT OF THERAPEUTIC DENTISTRY by Yu. V. Sidash

“…Such assessments should include an analysis of learning activities rather than criticism of the student's personality. …”
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Feasibility and Preliminary Effects of Acupuncture for Cognitive Dysfunction in Diverse Cancer Survivors: A Pilot, Randomized, Placebo-Controlled Trial by Xiaotong Li, Kaitlin Lampson, Tim A. Ahles, James C. Root, Q. Susan Li, Yuelin Li, Anam Ahsan, Jun J. Mao, Kevin T. Liou

“…Subjective CRCD was assessed by the Functional Assessment of Cancer Therapy-Cognitive Function—Perceived Cognitive Impairment subscale (FACT-Cog PCI) and objective CRCD was assessed by the Hopkins Verbal Learning Test—Revised (HVLT-R). (3) Results: 32 participants (57.1% of eligible patients) were enrolled. …”
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Working-memory load decoding model inspired by brain cognition based on cross-frequency coupling by Jing Zhang, Tingyi Tan, Yuhao Jiang, Congming Tan, Liangliang Hu, Daowen Xiong, Yikang Ding, Guowei Huang, Junjie Qin, Yin Tian

“…Working memory, a fundamental cognitive function of the brain, necessitates the evaluation of cognitive load intensity due to limited cognitive resources. …”
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Trans-cinnamaldehyde ameliorates neuroinflammation-mediated synaptic plasticity and memory impairment by blocking TLR4/MyD88/MAPKs pathway in global cerebral ischemia by Xinjuan Liu, Zhiyuan Lu, Gaiying He, Waimao Gao, Kaifan Hu, Jie Pan, Yan Zhao, Xingyu Wang, Guang Yang, Ying Xu

“…Behavioral tests, including the open field test, novel object recognition, and water maze, were conducted to assess cognitive function, while long-term potentiation (LTP) analysis was used to evaluate synaptic plasticity. …”
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Exacerbating effects of circadian rhythm disruption on the systemic lupus erythematosus by Jing Wang, Qing Liu, Fang Zhou, Guangji Wang, Xuan Luo, Ning Wei, Luping Shen, Mo Han, Qixiang Zhang, Huanke Xu

“…We aimed to investigate the impact of circadian rhythms on immune function and inflammation and their contribution to SLE progression to lupus nephritis (LN).Methods This study retrospectively analysed the clinical characteristics and transcriptional profiles of 373 samples using bioinformatics and machine-learning methods. …”
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Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer’s Disease Rats Based on the Wnt/β-catenin Pathway by Wen-jing Ning, Ren-jun Lv, Ning Xu, Xun-yao Hou, Chao Shen, Yun-liang Guo, Zhong-yu Fan, Na Cao, Xue-Ping Liu

“…To investigate the effects of lycopene-loaded microemulsion (LME) on the cognitive function and neurogenesis in the dentate gyrus (DG) of the hippocampus and subventricular (SVZ) region of rats with amyloid β- (Aβ-) induced Alzheimer’s disease (AD) and its mechanism based on the Wnt/β-catenin pathway. …”
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Modules of Organizational and Technical Systems for Solving Problems of Adaptation in a Rapidly Changing Environment by A. Mikryukov, V. M. Trembach, A. V. Danilov

“…In the case of expanding the functionality of the OTS modules of Internet of things, it is advisable to apply machine learning with fixing the results in the knowledge base of planning agents.…”
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Preliminary observations of glucose metabolism dysregulation in pediatric Huntington’s disease by Federica Graziola, Federica Rachele Danti, Martina Penzo, Antonio Spagarino, Eleonora Minacapilli, Marco Moscatelli, Federica Zibordi, Caterina Mariotti, Giovanna Zorzi, Giovanna Zorzi

“…However, systemic biochemical indicators of glucose transport deficiency, including erythrocyte GLUT1 function and CSF glucose, were not significantly altered. …”
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Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

“…Behavioral outcomes aligned with these biochemical changes, showing marked improvements in memory and learning, motor activity, seizure threshold, and anxiety-like behavior. …”
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TATPat based explainable EEG model for neonatal seizure detection by Turker Tuncer, Sengul Dogan, Irem Tasci, Burak Tasci, Rena Hajiyeva

“…Therefore, the proposed feature extraction function is termed Triple Nodes Automaton-based Transition table Pattern (TATPat). …”
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Exercise preconditioning alleviates photothrombotic ischemic stroke in mice by orchestrating neutrophils by Tae Yeon Kim, Yun Seo Cho, Jae Yeon Park, Songwon Woo, Kihoon Yuk, Dong Heon Yi, In cheol Jeong, In cheol Jeong, Jin Pyeong Jeon, Yoe-Sik Bae, Min-Chul Lee, Hyo Youl Moon, Hyo Youl Moon, Hyo Youl Moon

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Prevalence and Correlates of Neurocognitive Disorders among HIV Patients on Antiretroviral Therapy at a Kenyan Hospital by A. G. Mugendi, M. N. Kubo, D. G. Nyamu, L. M. Mwaniki, S. K. Wahome, J. E. Haberer

“…HIV-associated neurocognitive disorders (HAND) represent a spectrum of cognitive abnormalities affecting attention, concentration, learning, memory, executive function, psychomotor speed, and/or dexterity. …”
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GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer’s disease by Xiaoqin Wang, Shijing Wu, Zhangjing Deng, Mengyu Yan, Dandan Wang, Maojun Yang, Fuxing Zhong, Jiaqi Song, Lihua Chen, Yingxi Chen, Qi Tian, Weihua Yu, Yang Lü

“…GPR43 activation improved spatial learning and memory in AD mice. Furthermore, it upregulated the expression of brain-derived neurotrophic factor (BDNF), postsynaptic density protein 95 (PSD95), and synaptophysin (SYP), indicating enhanced neuronal and synaptic function. …”
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Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease by Roberta Marongiu, Roberta Marongiu, Roberta Marongiu, Jimcy Platholi, Jimcy Platholi, Laibak Park, Fangmin Yu, Garrett Sommer, Clara Woods, Teresa A. Milner, Michael J. Glass

“…Further, select increases in glial activation also paralleled Ab pathology in distinct hippocampal subregions. However, cognitive function was not affected by peri-AOF.DiscussionThese findings align with the hypothesis that perimenopause constitutes a period of susceptibility for AD pathogenesis in women.…”
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Identification of High-Photosynthetic-Efficiency Wheat Varieties Based on Multi-Source Remote Sensing from UAVs by Weiyi Feng, Yubin Lan, Hongjian Zhao, Zhicheng Tang, Wenyu Peng, Hailong Che, Junke Zhu

“…Furthermore, the research conducted principal component analysis (PCA) and membership function analysis on the predicted values of the optimal models for each indicator, established a comprehensive evaluation index for high photosynthetic efficiency, and employed cluster analysis to screen the test materials. …”
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Effect of Active Workstations on Neurocognitive Performance and Typing Skills: A Randomized Clinical Trial by Jose R. Medina‐Inojosa, Miguel A. Gomez Ibarra, Betsy J. Medina‐Inojosa, Marta Supervia, Sarah Jenkins, Lynne Johnson, Nathalie P. Suarez, Amanda Bonikowske, Virend K. Somers, Francisco Lopez‐Jimenez

“…Four office settings were evaluated on 4 consecutive days: stationary or sitting station on day 1 (referent), and 3 subsequent active workstations (standing, walking, or stepper) in randomized order. Neurocognitive function (Selective Attention, Grammatical Reasoning, Odd One Out, Object Reasoning, Visuospatial Intelligence, Limited‐Hold Memory, Paired Associates Learning, and Digit Span) and fine motor skills (typing speed and accuracy) were tested using validated tools. …”
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