Ferroptosis-disulfidptosis-related CHMP6 is a clinico-immune target in colorectal cancer by Yifei Zhu, Huixia Huang, Jiayu Chen, Keji Chen, Yanxi Yao, Yaxian Wang, Yuxue Li, Zhibing Qiu, Dawei Li, Ping Wei

“…Our findings established CHMP6 as a dual-function tumor suppressor that not only restrains tumor progression but also enhances immune-mediated tumor control. …”
Get full text

Biportal Endoscopic Intervention for Lumbar Disk Herniation: Evaluating Clinical Effectiveness and Patient Outcomes by Apoorv Kumar, Arohi Gupta, Sujith V Rao, Huzaifa A Ansari

“…However, challenges, including a learning curve for surgeons and practical obstacles, still exist. …”
Get full text

Electronic Nose System Based on Metal Oxide Semiconductor Sensors for the Analysis of Volatile Organic Compounds in Exhaled Breath for the Discrimination of Liver Cirrhosis Patient... by Makhtar War, Benachir Bouchikhi, Omar Zaim, Naoual Lagdali, Fatima Zohra Ajana, Nezha El Bari

“…Sensor’s measurement data were analyzed using machine learning techniques, such as principal component analysis (PCA), discriminant function analysis (DFA), and support vector machines (SVMs) that were utilized to uncover meaningful patterns and facilitate accurate classification of sensor-derived information. …”
Get full text

Lower Ipsilateral Hippocampal Integrity after Ischemic Stroke in Young Adults: A Long-Term Follow-Up Study. by Pauline Schaapsmeerders, Anil M Tuladhar, Noortje A M Maaijwee, Loes C A Rutten-Jacobs, Renate M Arntz, Hennie C Schoonderwaldt, Lucille D A Dorresteijn, Ewoud J van Dijk, Roy P C Kessels, Frank-Erik de Leeuw

“…One hundred and forty-six patients underwent T1 MPRAGE, DTI scanning and completed the Rey Auditory Verbal Learning Test and were compared with 84 stroke-free controls. …”
Get full text

Antenna systems for IoT applications: a review by Sunawar Khan, Tehseen Mazhar, Tariq Shahzad, Afsha Bibi, Wasim Ahmad, Muhammad Amir Khan, Mamoon M. Saeed, Habib Hamam

“…This research tackles these key elements to enable the next generation of antenna systems to meet IoT technology's expanding needs and increase networked devices' functionality, efficiency, and integration across industries. …”
Get full text

Time series AQI forecasting using Kalman-integrated Bi-GRU and Chi-square divergence optimization by Narmeen Fatima, Samia Nawaz Yousafzai, Nadhem Nemri, Hadeel Alsolai, Shouki A. Ebad, Shaymaa Sorour, Yeonghyeon Gu, Muhammad Syafrudin, Norma Latif Fitriyani

“…This study introduces a novel deep learning framework that integrates Kalman Attention with a Bi-Directional Gated Recurrent Unit (Bi-GRU) for robust AQI time-series forecasting. …”
Get full text

Edge_MVSFormer: Edge-Aware Multi-View Stereo Plant Reconstruction Based on Transformer Networks by Yang Cheng, Zhen Liu, Gongpu Lan, Jingjiang Xu, Ren Chen, Yanping Huang

“…With the rapid advancements in computer vision and deep learning, multi-view stereo (MVS) based on conventional RGB cameras has emerged as a promising and cost-effective tool for botanical research. …”
Get full text

The Impact of the Zoning System on the Professional Development of English Teachers by Muslem Muslem, Nina Afrida, Apriliana Zura

“…Education is one way to help people reach their full potential both academically and non-academically so they can fulfill the essential functions and goals of national education. The study aimedto determine the impact of the zoning system on learning English and the challenges for English teachers when the zoning system was implemented at SMPN 1 Langsa. …”
Get full text

Cumulative blood pressure load and cognitive decline in older adults: An observational analysis of two large cohorts by Ying Xu, G. Peggy McFall, Lina Rydén, Johan Skoog, Edward Chang, Lucette A. Cysique, Katie Harris, Sarah Kedwell, Mei Ling Lim, Kaarin J. Anstey, Craig S. Anderson, Roger A. Dixon, Ingmar Skoog, Phillip J. Tully, Ruth Peters

“…Introduction: Cumulative blood pressure metrics may provide greater precision for measuring temporal risk exposure, especially in later life where data are mixed regarding associations of high blood pressure (BP) on cognitive function. We examined the relationship between greater cumulative exposure to high BP in later life and several domains of cognitive function. …”
Get full text

Long-Term Efficacy of an AI-Based Health Coaching Mobile App in Slowing the Progression of Nondialysis-Dependent Chronic Kidney Disease: Retrospective Cohort Study by Jianwei Ma, Jiangyuan Wang, Jiapei Ying, Shasha Xie, Qin Su, Tianmeng Zhou, Fuman Han, Jiayan Xu, Siyi Zhu, Chenyi Yuan, Ziyuan Huang, Jingfang Xu, Xuyong Chen, Xueyan Bian

“…Subgroup analysis revealed that the effect of the KidneyOnline care group was more significant in male patients, patients older than 45 years, and patients with worse baseline kidney function, higher blood pressure, and heavier proteinuria. …”
Get full text

Egg freshness during storage: the effect of laying hen age and shelf life prediction using a novel hybrid modeling method by Yifeng Lu, Jing Li, Zihao He, Linyun Chen, Huixin Tian, Chen Xu, Xinglian Xu, Minyi Han

“…The tuning process of hyperparameters such as learning rate, training function, and transfer function was presented in detail. …”
Get full text

Ovarian Reserve: A Critical Indicator of Female Reproductive Health by Julia Ufnal, Anna Wolff, Maria Morawska, Dominika Lewandowska, Dominika Rosińska-Lewandoska, Marcelina Szewczyk, Klaudia Kożuchowska, Dawid Pilarz, Kinga Jarosz, Szymon Gruszka

“…The diverse influence of discussed factors on ovarian function underscores the need for individualized evaluation. …”
Get full text

Early prediction of long COVID-19 syndrome persistence at 12 months after hospitalisation: a prospective observational study from Ukraine by Dmytro Chumachenko, Tetyana Chumachenko, Oleksii Honchar, Tetiana Ashcheulova

“…Patients who reported incomplete recovery at 1 year were characterised by a higher burden of comorbidities (Charlson index of 0.69±0.96 vs 0.31±0.51, p=0.001) and residual pulmonary consolidations (1.56±1.78 vs 0.98±1.56, p=0.034), worse blood pressure (BP) control (systolic BP of 138.1±16.2 vs 132.2±15.8 mm Hg, p=0.041), renal (estimated glomerular filtration rate of 59.5±14.7 vs 69.8±20.7 mL/min/1.73 m2, p=0.007) and endothelial function (flow-mediated dilation of the brachial artery of 10.4±5.4 vs 12.4±5.6%, p=0.048), higher in-hospital levels of liver enzymes (alanine aminotransferase (ALT) of 76.3±60.8 vs 46.3±25.3 IU/L, p=0.002) and erythrocyte sedimentation rate (ESR) (34.3±12.1 vs 28.3±12.6 mm/h, p=0.008), slightly higher indices of ventricular longitudinal function (left ventricular (LV) global longitudinal strain (GLS) of 18.0±2.4 vs 17.0±2.3%, p=0011) and higher levels of Hospital Anxiety and Depression Scale anxiety (7.3±4.2 vs 5.6±3.8, p=0.011) and depression scores (6.4±3.9 vs 4.9±4.3, p=0.022) and EFTER-COVID study physical symptoms score (12.3±3.8 vs 9.2±4.2, p<0.001). …”
Get full text

Neuronal expression of CaMKⅡ and BDNF isoforms in mice with cognitive dysfunction induced by repetitive mild traumatic brain injury by LIU Dianqing, LIU Dianqing, LI Yun, LI Yun, ZHANG Jietao

“…Conclusion‍　‍In the chronic phase of rmTBI， prognosis of good cognitive function is accompanied by up-regulation of CaMKⅡ signaling pathway， and the difference in cognitive function is accompanied by the change in proportions of different AMPAR subunits on the postsynaptic membrane. …”
Get full text

Exosomes from IH- Induced bEnd3 Cells Promote OSA Cognitive Impairment via miR-20a-5p/MFN2 Mediated Pyroptosis of HT22 Cells by Chen Z, Shang Y, Ou Y, Zhou L, Liu T, Gong S, Xiang X, Peng Y, Ouyang R

“…The spatial memory ability of mice was tested by MWM method to evaluate the effect of exosomes on the cognitive function of mice. Adults diagnosed with OSA underwent the MoCA and ESS tests to assess cognitive function and daytime sleepiness. …”
Get full text

Tracking Clinical Competency Growth: A Longitudinal Study of Medical Students in a Multidisciplinary Emergency Department Internship Program by Sung TC, Shih HI, Kawaguchi T, Chi CH, Hsu HC

“…These findings underscore the importance of sustained, structured clinical experiences in preparing students to function effectively within interdisciplinary healthcare teams. …”
Get full text

Efficacy and safety of Neurocognitive Adaptive Training for Depression combined with SSRIs for treating cognitive impairment among patients with late-life depression: a 12-week, ra... by Xiao Wang, Jiaojiao Zhou, Kemeng Zhu, Yida Wang, Xianglin Ma, Li Ren, Chengwei Guo, Zhanjun Zhang, Peng Lu, Qinge Zhang

Get full text

Large-scale genomic analysis reveals significant role of insertion sequences in antimicrobial resistance of Acinetobacter baumannii by Fei Xie, Lifeng Wang, Song Li, Long Hu, Yanhua Wen, Xuming Li, Kun Ye, Zhimei Duan, Qi Wang, Yuanlin Guan, Ye Zhang, Qiqi Shi, Jiyong Yang, Han Xia, Lixin Xie

“…Our study advances this approach by integrating both rule-based and machine learning models to predict AMR in A. baumannii. This significantly enhances the accuracy of AMR prediction, emphasizing the pivotal function of IS elements in antibiotic resistance. …”
Get full text

Experiences of pacing to reduce symptoms among adults living with Long COVID in Canada, Ireland, the United Kingdom and the United States by Kiera McDuff, Darren A. Brown, Natalie St. Clair-Sullivan, Soo Chan Carusone, Kristine M. Erlandson, Lisa Avery, Ciaran Bannan, Colm Bergin, Angela M. Cheung, Susie Goulding, Richard Harding, Mary Kelly, Jessica M. Martin, Lisa McCorkell, Sarah O’Connell, Imelda O’Donovan, Margaret E. O’Hara, Niamh Roche, Ruth Stokes, Catherine Thomson, Liam Townsend, Jaimie H. Vera, Hannah Wei, Patricia Solomon, Kelly K. O’Brien

“…Abstract Background Long COVID is a multisystem condition that negatively impacts daily function. Pacing is a self-management strategy to mitigate symptoms. …”
Get full text

Association of spatiotemporal interaction of gamma oscillations with heart rate variability during response inhibition processing in patients with major depressive disorder: An MEG... by Junling Sheng, Yi Xia, Lingling Hua, Hongliang Zhou, Qian Liao, Shui Tian, Yishan Du, Xiaoqin Wang, Rui Yan, Hao Sun, Zhijian Yao, Qing Lu

Get full text