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4661
Development and Validation of a Machine Learning Model for Predicting Long-Term Depression Risk in ACS Patients After PCI: A Retrospective Cohort Study
Published 2025-06-01“…These models used routine clinical information like heart function, thyroid levels, and diabetes status to make predictions.The results showed that about 1 in 5 patients developed depression. …”
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4662
Developing a machine learning-based methodology for optimal hyperparameter determination—A mathematical modeling of high-pressure and high-temperature drilling fluid behavior
Published 2024-11-01“…Different configurations with different hidden layers, using neuron sequences of 16, 32, and 64, learning rates of 0.001 and 0.01, and the ReLU activation function were used to improve the model's performance. …”
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4663
HyperKon: A Self-Supervised Contrastive Network for Hyperspectral Image Analysis
Published 2024-09-01“…The use of a pretrained image classification model (trained on cats and dogs, for example) as a perceptual loss function for hyperspectral super-resolution and pansharpening tasks is surprisingly effective. …”
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4664
Charting the course of digital collaboration: a bibliometric analysis of COIL literature
Published 2025-12-01“…Collaborative Online International Learning (COIL) is a sustainable solution in which two cohorts of faculty and students from geographically and culturally diverse backgrounds can collaborate and interact thereby gaining skills to function in a multicultural and diverse global community. …”
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4665
Flow Cytometric Assessment of FcγRIIIa-V158F Polymorphisms and NK Cell Mediated ADCC Revealed Reduced NK Cell Functionality in Colorectal Cancer Patients
Published 2024-12-01“…Fc gamma receptor IIIa (FcγRIIIa) polymorphisms impact ADCC, yet their clinical relevance in NK cell functionality remains debated. We developed two complementary flow cytometry assays: one to predict the FcγRIIIa-V158F polymorphism using a machine learning model, and a 15-color flow cytometry panel to assess antibody-induced NK cell functionality and cancer-immune cell interactions. …”
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4666
Multi-View Cluster Structure Guided One-Class BLS-Autoencoder for Intrusion Detection
Published 2025-07-01“…Specifically, a multi-view co-association matrix optimization objective function with doubly-stochastic constraints is first designed to capture the cross-view cluster structure. …”
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4667
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4668
A novel network with enhanced edge information for left atrium segmentation from LGE-MRI
Published 2024-12-01“…The design of EIEM is grounded in exploring edge details within target region features learned from images. Additionally, it incorporates a Spatially Weighted Cross-Entropy loss function tailored for EIEM, introducing constraints on different regions based on the importance of pixels to edge segmentation, while also mitigating class imbalance through weighted treatment of positive and negative samples.ResultsThe proposed method is validated on the 2018 Atrial Segmentation Challenge dataset. …”
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4669
Mediating role of gut microbiota on Baduanjin for cognitive function in community-dwelling older adults with mild cognitive impairment: a study protocol for a cluster randomised co...
Published 2024-11-01“…Four residential communities (clusters) with a total of 64 eligible participants (16 participants in each residential community) will be randomised 1:1 to either the 24-week Baduanjin exercise intervention group (60 min per session, four sessions per week) or the no specific exercise intervention control group. Global cognitive function and the subdimensions of cognition including executive function, visuospatial function, language function and memory function will be assessed using the Montreal Cognitive Assessment Scale, Trail Making Test, Auditory Verbal Learning Test, Boston Naming Test-30 and Clock-Drawing Test, while the gut microbiome and its metabolomics will be detected using 16S rRNA and ultra-high-performance liquid chromatography–tandem mass spectrometry at baseline and at the end of 24-week intervention. …”
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4670
Dynamic Adjacency Matrix Learning and Multi-Order Random Walk Aggregation for Alzheimer’s Disease Diagnosis From Resting-State fMRI
Published 2025-01-01“…Alzheimer’s disease (AD) is a progressive, irreversible neurodegenerative disorder, and early diagnosis is critical for timely intervention and slowing down the course of the disease. Functional magnetic resonance imaging (fMRI), a non-invasive neuroimaging technique, can be used to detect functional brain activity. …”
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4672
Integrated multi-omics analysis and machine learning identify G protein-coupled receptor-related signatures for diagnosis and clinical benefits in soft tissue sarcoma
Published 2025-07-01“…Moreover, the GPR-TME classifier as the prognosis model was constructed and further performed for immune infiltration, functional enrichment, somatic mutation, immunotherapy response prediction, and scRNA-seq analyses.ResultsWe identified 151 GPR-related genes at both the single-cell and bulk transcriptome levels, and identified a Stepglm[both]+Enet[alpha=0.6] model with seven GPR-related genes as the final diagnostic predictive model with high accuracy and translational relevance using a 127-combination machine learning computational framework, and the GPR-integrated diagnosis nomogram provided a quantitative tool in clinical practice. …”
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4673
Diagnostic biomarkers and immune infiltration profiles common to COVID-19, acute myocardial infarction and acute ischaemic stroke using bioinformatics methods and machine learning
Published 2025-05-01“…Finally, genes selected through machine learning methods included: CLEC4E, S100A12, and IL1R2. …”
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4674
SugarViT-Multi-objective regression of UAV images with Vision Transformers and Deep Label Distribution Learning demonstrated on disease severity prediction in sugar beet.
Published 2025-01-01“…With concepts of DLDL, special loss functions, and a tailored model architecture, we develop an efficient Vision Transformer based model for disease severity scoring called SugarViT. …”
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4675
Mechanistic role of pyroptosis in Kawasaki disease: An integrative bioinformatics analysis of immune dysregulation, machine learning-based biomarker discovery, WGCNA, and drug repu...
Published 2025-01-01“…Through machine learning-based biomarker discovery, we identified MYD88 and S100A12 as critical pyroptosis-related genes in KD. …”
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4676
An Analysis of the Use of Puzzle-Based Learning Media in Enhancing Students' Interest in Science Subjects in Grade V at SD Negeri 19 Tulang Bawang Udik
Published 2025-05-01“…This media not only functions as a tool to increase students' concentration, but is also an effective way to increase interest in learning. …”
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4677
An Exploratory Study of Small-Group Learning Interactions in Pre-Clerkship Medical Education: Uncovering a Mismatch Between Student Perceptions and Real-Time Observations
Published 2024-11-01“…Small-group learning is a mainstay of medical education, and group functioning can have a major influence on these learning experiences. …”
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4678
Body Awareness Does Not Need a Pedigree: Mixed-Breed Dogs Rely More on Self-Representation Than Social Learning in a Spatial Task
Published 2025-02-01“…The dogs who watched the demonstration for longer in trial 3 chose the door less often in trial 4, which indicates social learning. By testing mixed-breed dogs, our results are minimally influenced by functional breed selection and serve as valuable baseline for testing complex socio-cognitive traits in companion dogs.…”
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4679
Bioinformatics-Driven Structural and Pharmacological Analysis of SLITRK1 in Tourette Syndrome: Impact of S656M Mutation Using Molecular Dynamics, Docking, and Reinforcement Learnin...
Published 2025-01-01“…Structural analyses revealed that the S656M mutation significantly alters SLITRK1’s 3D conformation, biological functions, and drug binding profiles. Among the tested drugs, Aripiprazole exhibited the highest binding affinity across various SLITRK1 variants, with reinforcement learning highlighting a notable interaction with the S659K mutation. …”
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4680
Deep‐GB: A novel deep learning model for globular protein prediction using CNN‐BiLSTM architecture and enhanced PSSM with trisection strategy
Published 2024-12-01“…Enzymes, among these globular proteins, facilitate biochemical reactions, while others, such as haemoglobin, contribute to essential physiological functions such as oxygen transport. Given the importance of these considerations, accurately identifying Globular proteins is essential. …”
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