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Medium term health and quality of life outcomes in a cohort of children with MIS-C in Cape Town, South Africa
Published 2025-01-01“…The PedsQL inventory revealed that 16.7% of the children with previous MIS-C showed a deficit in the physical domain compared to 60% of the children with JIA (p < 0.001). 12.5% of the children with previous MIS-C had a deficit in their psychosocial domain which included emotional, social, and educational scores, compared to 40% of the children with JIA (p = 0.035).ConclusionsIn a cohort of 24 South African children with previous MIS-C, no medical complications were reported. …”
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1402
Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements
Published 2024-03-01“…Here, we present a cryo-EM structure of the closed-state RAF1-HSP90-CDC37 complex, where the C-lobe of the RAF1 kinase domain binds to one side of the HSP90 dimer, and an unfolded N-lobe segment of the RAF1 kinase domain threads through the center of the HSP90 dimer. …”
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1403
Solutions innovantes mises en œuvre pour restaurer et assurer la santé d’une forêt : l’exemple du Bois-Landry
Published 2024-10-01“… Le domaine du Bois-Landry est une chênaie privée exploitée pour le bois, la chasse et l’accueil du public en hébergement insolite. …”
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1404
The Impact of Drug Treatment Courts on Recovery: A Systematic Review
Published 2013-01-01“…Few studies used drug-related life domains as an outcome measure and most of them yielded no effects. …”
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1405
Characterizations of Pairs of Rings with Few Non-Dedekind Intermediary Rings
Published 2022-01-01“…We determine the Dedekind domain pairs of rings; that is, pairs of rings R⊂S such that each intermediary ring in between R and S is a Dedekind domain. …”
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1406
Argon release, crystallization, morphological and optical changes of ion-beam sputtered Ta2O5 thin films during thermal treatments
Published 2025-01-01“…Atomic Force Microscopy (AFM) experiments detect a reduction of the surface roughness in the crystalline phase; domains with typical dimensions of the order of few microns appear in the crystal. …”
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1407
ZSM-Based E2E Security Slice Management for DDoS Attack Protection in MEC-Enabled V2X Environments
Published 2024-01-01“…Efficient resource and security management in multi-domain V2X environments is vital, especially with the growing threat of distributed denial-of-service (DDoS) attacks against critical V2X services within MEC. …”
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1408
Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design
Published 2021-09-01“…However, the impact of costimulatory domains on the efficacy of myeloid antigen-directed CAR T cell immunotherapy remains unknown.Methods In this preclinical study, we developed six CAR constructs targeting CD33, a highly expressed and validated AML target, comprised of one of three single-chain variable fragments with CD3ζ and either CD28 or 4-1BB costimulatory domains. …”
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1409
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1410
Hearing the shape of membranes: further results
Published 1990-01-01“…The spectral function θ(t)=∑m=1∞exp(−tλm), t>0 where {λm}m=1∞ are the eigenvalues of the Laplacian in Rn, n=2 or 3, is studied for a variety of domains. Particular attention is given to circular and spherical domains with the impedance boundary conditions ∂u∂r+γju=0 on Γj (or Sj), j=1,…,J where Γj and Sj, j=1,…,J are parts of the boundaries of these domains respectively, while γj, j=1,…,J are positive constants.…”
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1411
Research on Recognition of Quiet Period of Sandstone Acoustic Emission Based on Four Machine Learning Algorithms
Published 2022-01-01“…Based on AE time domain data, frequency domain data, and composite data (time-frequency domain data sets), the grid search traversal parameter technique was used to obtain the optimal parameters of four machine learning models. …”
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1412
TC2N maintains stem cell-like characteristics to accelerate lung carcinogenesis by blockade of dual specificity protein phosphatase 3
Published 2025-01-01“…Abstract Background Tandem C2 domains, nuclear (TC2N) is a protein that has been characterized to contain C2A domain, C2B domain, and a short C-terminus with a WHXL motif. …”
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1413
The relevance of a multidomain geriatric assessment in older patients with heart failure
Published 2020-06-01“…Compared with no domains affected, odds ratios (95% confidence interval) for 1, 2, and ≥3 domains were 1.8 (0.5–6.5), 4.5 (1.3–15.4), and 7.2 (2.0–26.3) (P‐trend <0.01). …”
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1414
Capturing Requirements for a Data Annotation Tool for Intensive Care: Experimental User-Centered Design Study
Published 2025-02-01“…Data annotation is a complex and time-consuming problem that requires domain expertise and frequently, technical proficiency. …”
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1415
The implementation, use and impact of patient reported outcome measures in value-based healthcare programmes: A scoping review.
Published 2023-01-01“…An a priori data extraction framework was created using the review question and objectives as key domains against which to extract data. Mixed-methods data were organised, integrated and preserved in original format and reported for each domain.…”
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1416
Ammonium Transporter 1 (<i>AMT1</i>) Gene Family in Pomegranate: Genome-Wide Analysis and Expression Profiles in Response to Salt Stress
Published 2025-01-01“…This study evaluated the isoelectric point, hydropathicity, conserved domains, motifs, and synteny of the PgAMT1 proteins. …”
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1417
Exploring the relationship between personality traits, social appearance anxiety, and quality of life among nursing students
Published 2025-01-01“…Additionally, (WHOQOL-Brief), general health, and social domains had the highest mean scores (58.2 and 53.2), compared to the physical domain, which scored the lowest at (40.6). …”
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1418
Gastrointestinal Dysfunction Impact on Life Quality in a Cohort of Russian Patients with Parkinson’s Disease I-III H&Y Stage
Published 2022-01-01“…The investigation of GSRS domain’s influence revealed that PDQ-39 SI had a significant correlation with almost all of them, but the regression analysis showed significant QoL impacts of only two factors: constipation and abdominal pain (β = 0.288, p<0.01 and β = 0.243, p<0.05 accordingly). …”
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1419
Multiphysics Modeling of Gas Turbine Based on CADSS Technology
Published 2020-01-01“…Multiphysics model representation was analyzed to verify gaps among different domain models’ parameters. Therefore, multiphysics domain model architecture was integrated by optimization model, design model, and simulation model in consideration of domain model’s parameters. …”
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1420
Age-structured cell population model to study the influence of growth factors on cell cycle dynamics
Published 2012-11-01Get full text
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