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Challenges with reinforcement learning model transportability for sepsis treatment in emergency care
Published 2025-02-01Get full text
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Targeting KRAS‐mutant pancreatic cancer through simultaneous inhibition of KRAS, MEK, and JAK2
Published 2025-02-01Get full text
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Traitement d’un lymphome agressif chez un babouin naturellement infecté par STLV-1
Published 2016-01-01Get full text
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Junior high school's EFL teachers' reading habits and literacy practices
Published 2025-02-01Get full text
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Deep Learning Implementation Using CNN to Classify Bali God Sculpture Pictures
Published 2024-07-01Get full text
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Marginal and Internal Adaptation Evaluation of Dental Composites Using Micro-CT
Published 2019-01-01Get full text
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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes
Published 2021-09-01“…Melanoma cells containing an IFN-γ receptor (IFNγR) cytoplasmic domain deletion mutant was overexpressed and used for characterization of the metabolic profile of those tumor cells using a Seahorse Flux Analyzer.Results Met administration elevates mtROS and cell surface Glut-1, resulting in the production of IFN-γ in CD8TILs. mtROS activates Nrf2 in a glycolysis-dependent manner, inducing activation of autophagy, glutaminolysis, mTORC1, and p62/SQSTM1. mTORC1-dependent phosphorylation of p62 at serine 351 (p-p62(S351)) is also involved in activation of Nrf2. …”
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Prevalence, management, and outcomes of haemorrhagic events in left ventricular assist device recipients
Published 2022-06-01Get full text
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