Adaptive spatial-channel feature fusion and self-calibrated convolution for early maize seedlings counting in UAV images by Zhenyuan Sun, Zhenyuan Sun, Zhenyuan Sun, Zhi Yang, Zhi Yang, Yimin Ding, Yimin Ding, Boyan Sun, Boyan Sun, Saiju Li, Saiju Li, Zhen Guo, Zhen Guo, Lei Zhu, Lei Zhu

“…The RSCconv layer improves the representation of early maize seedlings compared to non-seedling elements within feature maps by calibrating spatial domain features. The ASCFF module enhances the discriminability of early maize seedlings by adaptively fusing feature maps extracted from different layers of the backbone network. …”
Get full text

SF1-specific deletion of the energy sensor AMPKγ2 induces obesity by Óscar Freire-Agulleiro, Ánxela Estévez-Salguero, Vitor Ferreira, Cassie Lynn Holleman, Julia García-Currás, Ismael González-García, Rubén Nogueiras, Manuel Tena-Sempere, Cristina García-Cáceres, Carlos Diéguez, Miguel López

“…Objective: AMP-activated protein kinase (AMPK) is a heterotrimer complex consisting of a catalytic α subunit (α1, α2) with a serine/threonine kinase domain, and two regulatory subunits, β (β1, β2) and γ (γ1, γ2, γ3), encoded by different genes. …”
Get full text

Use of Digital Health Technologies for Dementia Care: Bibliometric Analysis and Report by Hebatullah Abdulazeem, Israel Júnior Borges do Nascimento, Ishanka Weerasekara, Amin Sharifan, Victor Grandi Bianco, Ciara Cunningham, Indunil Kularathne, Genevieve Deeken, Jerome de Barros, Brijesh Sathian, Lasse Østengaard, Frederique Lamontagne-Godwin, Joost van Hoof, Ledia Lazeri, Cassie Redlich, Hannah R Marston, Ryan Alistair Dos Santos, Natasha Azzopardi-Muscat, Yongjie Yon, David Novillo-Ortiz

“…Our assessment of contributions from countries, institutions, and key stakeholders reveals significant trends and knowledge gaps, particularly highlighting the dominance of high-income countries in this research domain. Furthermore, our findings emphasize the critical importance of interdisciplinary, collaborative teams and offer clear directions for future research, especially in underrepresented regions. …”
Get full text

SOA Services Identification and Design Methods From Business Models: A Systematic Literature Review by Redouane Blal, Abderrahmane Leshob, Hafedh Mili, Imen Benzarti, Pierre Hadaya, Raqeebir Rab

“…However, designing such SOA services is a complex task that requires extensive knowledge and skills in software architecture and the business domain. Researchers and practitioners have proposed several methods to derive SOA services from business models during the last two decades. …”
Get full text

Social learning activities to improve community engagement in waste management program by S. Sunarti, R.S.Y. Zebua, J.H. Tjakraatmadja, A. Ghazali, B. Rahardyan, K. Koeswinarno, S. Suradi, N. Nurhayu, R.H.A. Ansyah

“…Further path model analysis demonstrated that without “Affective Factors” being nurtured, learning activities and Facilities would not be able to improve behavior significantly, as all paths directing to Behavioral Domain (Intention and WMB) had an insignificant effect (P value > 0.05).CONCLUSION: This study offered empirical evidence, showing the mechanism of social learning to improve waste management behavior. …”
Get full text

Giant energy storage density with ultrahigh efficiency in multilayer ceramic capacitors via interlaminar strain engineering by Ying Yang, Ke Xu, Bin Yang, Xu Hou, Zhanming Dou, Yuhong Li, Zihao Zheng, Gengguang Luo, Nengneng Luo, Guanglong Ge, Jiwei Zhai, Yuanyuan Fan, Jing Wang, Haoming Yang, Yao Zhang, Jing Wang, Changyuan Wang, Shenglin Jiang, Kanghua Li, Jinming Guo, Houbing Huang, Guangzu Zhang

“…Herein, for the purpose of decoupling the inherent conflicts between high polarization and low electric hysteresis (loss), and achieving high energy storage density and efficiency simultaneously in multilayer ceramic capacitors (MLCCs), we propose an interlaminar strain engineering strategy to modulate the domain structure and manipulate the polarization behavior of the dielectric mediums. …”
Get full text

Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB by Yongzhan Sun, Quan Zou, Huizheng Yu, Xiaoping Yi, Xudan Dou, Yu Yang, Zhiheng Liu, Hong Yang, Junya Jia, Yupeng Chen, Shao-Kai Sun, Lirong Zhang

“…Mechanistically, we observed that MMPP directly binds to the bZIP DNA-binding domain of CREB, leading to competitive inhibition of CREB’s DNA binding ability and subsequent reduction in CREB target gene expression. …”
Get full text

Investigating the Role of Artificial Intelligence Enablers and Companies' Readiness in Adopting an Artificial Intelligence-integrated Customer Relationship Management System by Soheila Mohammadzadeh Vanestan, Rahim Abedi

“…A fundamental aspect in this domain revolves around the acceptance of technology. …”
Get full text

Unveiling GPT-4V's hidden challenges behind high accuracy on USMLE questions: Observational Study by Zhichao Yang, Zonghai Yao, Mahbuba Tasmin, Parth Vashisht, Won Seok Jang, Feiyun Ouyang, Beining Wang, David McManus, Dan Berlowitz, Hong Yu

“…When GPT-4V answered correctly, its explanations were nearly as good as those provided by domain experts from AMBOSS. However, incorrect answers often had poor explanation quality: 18.2% (10/55) contained inaccurate text, 45.5% (25/55) had inference errors, and 76.3% (42/55) demonstrated image misunderstandings. …”
Get full text

Continuous theta-burst stimulation demonstrates language-network-specific causal effects on syntactic processing by Chenyang Gao, Junjie Wu, Yao Cheng, Yuming Ke, Xingfang Qu, Mingchuan Yang, Gesa Hartwigsen, Luyao Chen

“…These results shed light on the uniqueness and the specific causal role of the language network for the human language faculty, further supporting the causally separable view of the functional dissociation between the language network and the domain-general/multiple-demand network.…”
Get full text

Effect of an Internet-Based Pilates Telerehabilitation Intervention in People With Multiple Sclerosis: Protocol for a Randomized Controlled Trial by Andrea Tacchino, Michela Ponzio, Paolo Confalonieri, Letizia Leocani, Matilde Inglese, Diego Centonze, Eleonora Cocco, Paolo Gallo, Damiano Paolicelli, Marco Rovaris, Loredana Sabattini, Gioacchino Tedeschi, Luca Prosperini, Francesco Patti, Edoardo Sessa, Elisabetta Pedrazzoli, Mario Alberto Battaglia, Giampaolo Brichetto

“…ObjectiveThis paper presents the protocol for a study that aims to evaluate the efficacy on the physical domain (specifically balance and gait) of a home-based, self-managed PA intervention delivered through the MS-FIT exergame (HELAGLOBE Società a responsabilità limitata). …”
Get full text

Genome-wide identification of novel flagellar motility genes in Pseudomonas syringae pv. tomato DC3000 by Zichu Yang, Tyler Helmann, Maël Baudin, Maël Baudin, Maël Baudin, Karl J. Schreiber, Karl J. Schreiber, Zhongmeng Bao, Paul Stodghill, Paul Stodghill, Adam Deutschbauer, Adam Deutschbauer, Jennifer D. Lewis, Jennifer D. Lewis, Bryan Swingle, Bryan Swingle

“…PSPTO_4229 encodes a protein containing an HD-related output domain (HDOD), but with no previously identified functions. …”
Get full text

Systematic review and meta-analysis to examine intrapartum interventions, and maternal and neonatal outcomes following immersion in water during labour and waterbirth by Priscilla J Hall, Claire Feeley, Ethel Burns, Jennifer Vanderlaan

“…Risk of bias assessment included review of seven domains based on the Robbins-I Risk of Bias Tool. …”
Get full text

Longitudinal health-related quality of life in patients with pancreatic cancer stratified by treatment: a nationwide cohort studyResearch in context by Anne M. Gehrels, Pauline A.J. Vissers, Mirjam A.G. Sprangers, Nienke M. Fijnheer, Esther N. Pijnappel, Lydia G. van der Geest, Geert A. Cirkel, Judith de Vos-Geelen, Marjolein Y.V. Homs, Geert- Jan Creemers, Martijn W.J. Stommel, Lois A. Daamen, Marc G. Besselink, Johanna W. Wilmink, Hanneke W.M. van Laarhoven

“…Interpretation: This nationwide study identified specific improvements and deteriorations in various HRQoL domains during 6 months follow-up. This information may be valuable in the clinical setting to inform patients on potential outcomes of the course of HRQoL during various treatment strategies. …”
Get full text

Psychological discomfort in carriers and non-carriers of the Huntington disease mutation and its relationship with disease burden by Y. Rodríguez-Agudelo, M. Chávez-Oliveros, A. Ochoa-Morales, L. Martínez-Ruano, A. Camacho-Molina, F. Paz-Rodríguez

“…The correlations between disease burden and psychological distress occur in the domains; obsessions and compulsions, interpersonal sensitivity, hostility, global severity index and positive somatic distress index. …”
Get full text

Understanding social behaviours across neurodiverse young people: roles of social cognition and self-regulation by Iciar Iturmendi-Sabater, Evdokia Anagnostou, Marc A. Fournier, Jennifer Crosbie, Russell Schachar, Robert Nicolson, Stelios Georgiadis, Elizabeth Kelley, Jessica Jones, Jessica Brian, Hsiang-Yuan Lin, Meng-Chuan Lai

“…Social behaviours and dysregulation were measured by the caregiver-reported Adaptive Behavior Assessment System Social domain and Child Behavior Checklist Dysregulation Profile, respectively. …”
Get full text

Interior Peak Solutions for a Semilinear Dirichlet Problem by Hissah Alharbi, Hibah Alkhuzayyim, Mohamed Ben Ayed, Khalil El Mehdi

“…In this paper, we consider the semilinear Dirichlet problem <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mrow><mo>(</mo><msub><mi mathvariant="script">P</mi><mi>ε</mi></msub><mo>)</mo></mrow><mo>:</mo><mo>−</mo><mo>Δ</mo><mi>u</mi><mo>+</mo><mi>V</mi><mrow><mo>(</mo><mi>x</mi><mo>)</mo></mrow><mi>u</mi><mo>=</mo><msup><mi>u</mi><mrow><mstyle scriptlevel="0" displaystyle="true"><mfrac><mrow><mi>n</mi><mo>+</mo><mn>2</mn></mrow><mrow><mi>n</mi><mo>−</mo><mn>2</mn></mrow></mfrac></mstyle><mo>−</mo><mi>ε</mi></mrow></msup></mrow></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>u</mi><mo>></mo><mn>0</mn></mrow></semantics></math></inline-formula> in <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>Ω</mo></mrow></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>u</mi><mo>=</mo><mn>0</mn></mrow></semantics></math></inline-formula> on ∂<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>Ω</mo></mrow></semantics></math></inline-formula>, where <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>Ω</mo></mrow></semantics></math></inline-formula> is a bounded regular domain in <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi mathvariant="double-struck">R</mi><mi>n</mi></msup></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>n</mi><mo>≥</mo><mn>4</mn></mrow></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>ε</mi></semantics></math></inline-formula> is a small positive parameter, and <i>V</i> is a non-constant positive <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi>C</mi><mn>2</mn></msup></semantics></math></inline-formula>-function on <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mover><mo>Ω</mo><mo>¯</mo></mover></semantics></math></inline-formula>. …”
Get full text

ICOS Potenza (Italy) Atmospheric Station: A New Spot for the Observation of Greenhouse Gases in the Mediterranean Basin by Emilio Lapenna, Antonella Buono, Alessandro Mauceri, Isabella Zaccardo, Francesco Cardellicchio, Francesco D’Amico, Teresa Laurita, Davide Amodio, Canio Colangelo, Gianluca Di Fiore, Antonella Gorga, Ermann Ripepi, Francesco De Benedictis, Silvana Pirelli, Liborio Capozzo, Vincenzo Lapenna, Gelsomina Pappalardo, Serena Trippetta, Lucia Mona

“…In this context, the recently implemented class 1 continental station near Potenza in Basilicata, Italy—station code: POT—represents an important step forward in the extension of the ICOS atmosphere domain across the South, reducing the large spatial gaps existing between ICOS sites within the Mediterranean basin. …”
Get full text

Microcephaly protein ANKLE2 promotes Zika virus replication by Adam T. Fishburn, Cole J. Florio, Thomas N. Klaessens, Brian Prince, Neil A. B. Adia, Nicholas J. Lopez, Nitin Sai Beesabathuni, Sydney S. Becker, Liubov Cherkashchenko, Sophia T. Haggard Arcé, Vivian Hoang, Traci N. Shiu, R. Blake Richardson, Matthew J. Evans, Claudia Rückert, Priya S. Shah

“…We previously mapped ZIKV-host protein interactions and identified the interaction between ZIKV non-structural protein 4A (NS4A) and host microcephaly protein ankyrin repeat and LEM domain-containing 2 (ANKLE2). Using a fruit fly model, we showed that NS4A induced microcephaly in an ANKLE2-dependent manner. …”
Get full text

In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection by Yuta Suzuki, Takayuki Miyazaki, Yoko Ida, Tatsuya Suzuki, Yumi Itoh, Shuto Nakao, Keita Kondo, Kenji Kubara, Keisuke Nishioka, Hiroki Muto, Ryuji Watari, Toshifumi Hirayama, Dai Kakiuchi, Shinya Sato, Satoshi Inoue, Yoshifumi Uemoto, Yohei Mukai, Atsushi Hoshino, Toru Okamoto, Junji Matsui

“…Here, we designed an mRNA encoding an engineered angiotensin-converting enzyme 2 (ACE2) decoy, 3N39v4, composed of high-affinity ACE2 and a human immunoglobulin G Fc domain. The 3N39v4-encoded mRNA was encapsulated in lipid nanoparticles for efficient in vivo delivery. …”
Get full text