A Conserved Di-Lysine Motif in the E2 Transactivation Domain Regulates MmuPV1 Replication and Disease Progression by Jessica Gonzalez, Marsha DeSmet, Elliot J. Androphy

“…A highly conserved di-lysine motif within the transactivation domain (TAD) has been shown to regulate the normal functions of the E2 proteins of BPV-1, SfPV1, HPV-16, and HPV-31. …”
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Existence and Uniqueness of the Exponentially Stable Limit Cycle for a Class of Nonlinear Systems via Time-Domain Approach with Differential Inequality by Yeong-Jeu Sun, Yu-Biaw Wu, Ching-Cheng Wang

“…The concept of the exponentially stable limit cycle (ESLC) is introduced, and the ESLC phenomenon for a class of nonlinear systems is explored. Based on time-domain approach with differential inequality, the existence and uniqueness of the ESLC for such nonlinear systems can be guaranteed. …”
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La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine by Laetitia Borau

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Novel Metrics for High-Density sEMG Analysis in the Time–Space Domain During Sustained Isometric Contractions by Giovanni Corvini, Michail Arvanitidis, Deborah Falla, Silvia Conforto

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A Synthetic Solution for Identification and Extraction of the Effective Microseismic Wave Component Using Decomposition on Time, Frequency, and Wavelet Coefficient Domains by Mingwei Zhang, Qingbin Meng, Shengdong Liu, Hideki Shimada

“…To reduce noise components from original microseismic waves, a comprehensive fine signal processing approach using the integrated decomposition analysis of the wave duration, frequency spectrum, and wavelet coefficient domain was developed and implemented. Distribution regularities of the wave component and redundant noise on the frequency spectrum and the wavelet coefficient domain were first expounded. …”
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Normalization-Guided and Gradient-Weighted Unsupervised Domain Adaptation Network for Transfer Diagnosis of Rolling Bearing Faults Under Class Imbalance by Hao Luo, Xinyue Wang, Li Zhang

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Collision Avoidance for Maritime Autonomous Surface Ships Based on Model Predictive Control Using Intention Data and Quaternion Ship Domain by Hanxuan Zhang, Yuchi Cao, Qihe Shan, Yukun Sun

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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…SYK interacts with the Fc receptor by binding to doubly phosphorylated ITAM (p-ITAM) via its two tandem SH2 domains (SYK-tSH2). Interaction of the FCER1G p-ITAM with SYK-tSH2 enables SYK activation via phosphorylation. …”
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Fixation and reversion of mutations in the receptor-binding domain of the SARS-CoV-2 spike protein: A 2020–2024 analysis by Daniele Focosi, Pietro Giorgio Spezia, Fabrizio Maggi

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A universal and wide-range cytosine base editor via domain-inlaid and fidelity-optimized CRISPR-FrCas9 by Lan Hu, Jing Han, Hao-Da Wang, Zhou-Hua Cheng, Chang-Ce Lv, Dong-Feng Liu, Han-Qing Yu

“…Here, a series of iteratively improved cytosine base editors (CBEs) are constructed using the FrCas9 nickase (FrCas9n) with the unique PAM palindromic structure (NNTA) to alleviate these challenges. The deaminase domain-inlaid FrCas9n exhibits an editing range covering 38 nucleotides upstream and downstream of the palindromic PAM, without context preference, which is 6.3 times larger than that of traditional CBEs. …”
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Lopinavir and Ritonavir have High Affinity Toward the SARS-CoV-2 S-protein Receptor-binding Domain Sequenced in Brazil by Aline Diogo Marinho, Helyson Lucas Bezerra Braz, João Alison de Moraes Silveira, Danilo Galvão Rocha, Roberta Jeane Bezerra Jorge, Geanne Matos de Andrade

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A CBA-KELM-Based Recognition Method for Fault Diagnosis of Wind Turbines with Time-Domain Analysis and Multisensor Data Fusion by Xiafei Long, Ping Yang, Hongxia Guo, Zhuoli Zhao, Xiwen Wu

“…In this paper, a novel fault diagnosis methodology based on a cloud bat algorithm (CBA)-kernel extreme learning machines (KELM) approach for wind turbines is proposed via combination of the multisensor data fusion technique and time-domain analysis. First, the derived method calculates the time-domain indices of raw signals, and the fused time-domain indexes dataset are obtained by the multisensor data fusion. …”
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Les broyeurs en pierre en forme de doigt dans le sud-est de la Gaule romaine by Yves Manniez, Vincent Lauras

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Hercule, le lion et le cheval : les bronzes romains du puits 269 de Châteaumeillant/Mediolanum (Cher) by Sophie Krausz, Gérard Coulon

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Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor cells of metastatic breast cancer patients by Kai Bartkowiak, Parinaz Mossahebi Mohammadi, Paula Nissen, Stefan Werner, David Agorku, Antje Andreas, Maria Geffken, Sven Peine, Karl Verpoort, Thomas M. Deutsch, Laura L. Michel, Andreas Schneeweiss, Verena Thewes, Andreas Trumpp, Olaf Hardt, Volkmar Müller, Sabine Riethdorf, Hartmut Schlüter, Klaus Pantel

“…After a LC-MC/MS based proteomics analysis of CTC-ITB-01, we found extraordinary high levels of the poorly characterized protein SUSD2 (sushi domain-containing protein 2) in CTC-ITB-01. Expression of SUSD2 on subsets of CTCs was validated on clinical blood samples of patients with metastatic breast cancer. …”
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Prediction of Causative Genes in Inherited Retinal Disorders from Spectral-Domain Optical Coherence Tomography Utilizing Deep Learning Techniques by Yu Fujinami-Yokokawa, Nikolas Pontikos, Lizhu Yang, Kazushige Tsunoda, Kazutoshi Yoshitake, Takeshi Iwata, Hiroaki Miyata, Kaoru Fujinami, on behalf of Japan Eye Genetics Consortium

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3C-BASED METHODS FOR 3D GENOME ORGANIZATION ANALYSIS by N. R. Battulin, V. S. Fishman, Yu. L. Orlov, A. G. Menzorov, D. A. Afonnikov, O. L. Serov

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The protein structurome of Orthornavirae and its dark matter by Pascal Mutz, Antonio Pedro Camargo, Harutyun Sahakyan, Uri Neri, Anamarija Butkovic, Yuri I. Wolf, Mart Krupovic, Valerian V. Dolja, Eugene V. Koonin

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Villa d’époque romaine et habitat médiéval à Mont-Saint-Jean (Sarthe) : bilan des recherches 2008-2020 by Florian Sarreste, Paul-André Besombes, Phaedra Bouvet, Chloé Genies, Étienne Jaffrot, Florian Jedrusiak, Thomas Jubeau, Anthony Ledauphin, Annaïg Le Martret, Christophe Loiseau, Hugo Meunier, Aurore Noël, Sandrine Paradis-Grenouillet, Boris Robin

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Expression of Heme Oxygenase-1 Mediated by A Protein Transduction Domain Protects Insulin Producing Cells from Cytokine- Induced Cytotoxicity by Melina Ribeiro, Dagmar Klein, Antonello Pileggi, R. Damaris Molano, CHristopher Fraker, Camillo Ricordi, Luca Inverardi

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