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  1. 5821
  2. 5822

    A maturity model for Clinical Trials Management Ecosystem by Shruti Sehgal, E. Chris Pua, Svetlana Rojevsky, Michael J. Becich, Joshua Fehrmann, Boyd M. Knosp, Adam Wilcox, Jeffery C. Talbert, Catherine K. Craven, Justin Starren

    Published 2025-01-01
    “…An online session on maturity models was hosted, followed by a review of the candidate domain axes and finalization of the axes. Next, maturity level attributes were defined for min/max levels (level 1 and level 5) for each axis of the CTME MM, followed by the intermediate levels. …”
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  3. 5823

    Insights on the Permian tuff beds from the Saint-Affrique Basin (Massif Central, France): an integrated geochemical and geochronological study by Poujol, Marc, Mercuzot, Mathilde, Lopez, Michel, Bourquin, Sylvie, Bruguier, Olivier, Hallot, Erwan, Beccaletto, Laurent

    Published 2023-01-01
    “…In the Eastern Pangea intertropical domain (i.e. the present-day Western Europe), the late-Paleozoic (i.e. uppermost Carboniferous–Permian) history remains poorly constrained due to the lack of precise radiometric data. …”
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  4. 5824

    Spectral Analysis of Light-Adapted Electroretinograms in Neurodevelopmental Disorders: Classification with Machine Learning by Paul A. Constable, Javier O. Pinzon-Arenas, Luis Roberto Mercado Diaz, Irene O. Lee, Fernando Marmolejo-Ramos, Lynne Loh, Aleksei Zhdanov, Mikhail Kulyabin, Marek Brabec, David H. Skuse, Dorothy A. Thompson, Hugo Posada-Quintero

    Published 2024-12-01
    “…In a series of ERGs collected in ASD (<i>n</i> = 77), ADHD (<i>n</i> = 43), ASD + ADHD (<i>n</i> = 21), and control (<i>n</i> = 137) groups, this analysis explores the use of machine learning and feature selection techniques to improve the classification between these clinically defined groups. Standard time domain and signal analysis features were evaluated in different machine learning models. …”
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  5. 5825

    TEAD1‐Mediated Trans‐Differentiation of Vascular Smooth Muscle Cells into Fibroblast‐Like Cells Contributes to the Stabilization and Repair of Disrupted Atherosclerotic Plaques... by Ming Zhai, Zhijun Lei, Yefei Shi, Jiayun Shi, Yanxi Zeng, Shiyu Gong, Weixia Jian, Jianhui Zhuang, Qing Yu, Mark W. Feinberg, Wenhui Peng

    Published 2025-02-01
    “…Further investigation identified TEA domain transcription factor 1 (TEAD1) as the key transcription factor driving the trans‐differentiation of VSMCs into fibroblast‐like cells. …”
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  6. 5826

    OPTIMIZATION PROBLEM FOR NUMBER OF LOGIC GATES NEEDED TO IMPLEMENT MULTIPLE BOOLEAN FUNCTIONS USING DECODER by M. Onai, H. Skopyk

    Published 2024-12-01
    “…Since the program essentially offers workload management, its possible applications go beyond the domain of digital electronics. Additionally, the theory of optimizing the use of LEs is presented for the first time. …”
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  7. 5827

    Advancements and trends in mangrove species mapping based on remote sensing: A comprehensive review and knowledge visualization by Yuqi Wu, Chunyan Lu, Kexin Wu, Wenna Gao, Nuocheng Yang, Jingwen Lin

    Published 2025-01-01
    “…This paper employs CiteSpace to visualize the literature and presents a comprehensive review of the researches conducted in this domain, focusing primarily on bibliometric characteristics, diverse sensors, and classification algorithms. …”
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  8. 5828

    Characterization and Comparative Analysis of RWP-RK Proteins from Arachis duranensis, Arachis ipaensis, and Arachis hypogaea by Chenyang Liu, Dongliang Yuan, Tong Liu, Mengge Xing, Wenying Xu, Huiying Zhang, Hanqi Jin, Chunmei Cai, Shuai Li

    Published 2020-01-01
    “…The RWP-RK proteins were classified into two groups, RWP-RK domain proteins and NODULE-INCEPTION-like proteins. …”
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  9. 5829
  10. 5830

    New Circumpapillary Retinal Nerve Fiber Layer Thickness and Bruch’s Membrane Opening-Minimum Rim Width Assessment in Nonglaucomatous Eyes with Large Discs by Serife Bayraktar, Gulnar Sultanova, Zafer Cebeci, Emre Altinkurt, Belgin Izgi

    Published 2019-01-01
    “…To compare the new spectral-domain optical coherence tomography (SD-OCT) algorithm for measuring circumpapillary retinal nerve fiber layer (RNFL) thickness centered on Bruch’s membrane opening (BMO), RNFLBMO1, with the conventional circumpapillary RNFL thickness measurement centered on the optic disc (RNFLDİ), and assess the BMO-minimum rim width (BMO-MRW) in nonglaucomatous eyes with large discs. …”
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  11. 5831

    NUDT21 regulates lysyl oxidase-like 2(LOXL2) to influence ECM protein cross-linking in silica-induced pulmonary fibrosis by Lan Peng, Wenqing Sun, Demin Cheng, Xinying Jia, Wenxiu Lian, Ziwei Li, Haojie Xiong, Ting Wang, Yi Liu, Chunhui Ni

    Published 2025-01-01
    “…We then used scavenger receptor cysteine-rich (SRCR) domains to show that LOXL2 can induce fibrosis independently of its enzymatic activity. …”
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  12. 5832

    Role of visual function and performance of activities of daily living in cognitive function in patients with mild cognitive impairment: a cross-sectional study by Chunhui Zhou, Ganfeng Yang, Marc Theeboom, Hua Yang, Ruiting Zhu, Zijian Zhou, Dong Zhu

    Published 2025-02-01
    “…Specifically, it seeks to determine how different aspects of visual function, such as visual field indices and visual acuity, correlate with various cognitive domains measured by standardized assessments. Additionally, the study aims to examine the role of ADLs as a potential moderating factor in this relationship. …”
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  13. 5833

    Blended digital health intervention for adolescents at high risk with digital media use disorders: protocol for a randomised controlled trial within the Res@t-Consortium by Oliver Labrenz, Oliver Labrenz, Lucie Waedel, Lucie Waedel, Michael Kölch, Michael Kölch, Susanne Lezius, Christina Wacker, Antonia Fröhlich, Antonia Fröhlich, Kerstin Paschke, Rainer Thomasius, Olaf Reis, Olaf Reis

    Published 2025-01-01
    “…BackgroundDigital media use disorder (DMUD) is a prevalent problem among young people, which can result in adverse consequences and functional impairments across multiple domains of life due to a persistent inability to regulate one’s use, which can lead to the development of psychological problems. …”
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  14. 5834

    TIGIT inhibitor M6223 as monotherapy or in combination with bintrafusp alfa in patients with advanced solid tumors: a first-in-human, phase 1, dose-escalation trial by Wei Gao, Ping Hu, Aung Naing, Meredith McKean, Anthony Tolcher, Lillian L Siu, Keyvan Tadjalli-Mehr, Anja Victor, Emilia Richter, Marco A F Nogueira Filho, Thomas Kitzing, Stephan Gleicher, Daniel Holland

    Published 2025-02-01
    “…Background M6223 is an intravenous (IV), Fc-competent, fully human, antagonistic, anti-T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domains (TIGIT) antibody. Bintrafusp alfa (BA) is a bifunctional fusion protein that simultaneously blocks nonredundant immunosuppressive TGF-β and PD-(L)1 pathways.Methods This first-in-human, dose-escalation study in patients with advanced solid tumors (N=58; aged ≥18 years, ECOG PS≤1) evaluated M6223 alone (Part 1A, n=40; M6223 10–2400 mg every 2 weeks, n=32; M6223 2400 mg every 3 weeks, n=8) or with BA (Part 1B, n=18; M6223 300–1600 mg with BA 1200 mg; both every 2 weeks, intravenous). …”
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  15. 5835

    Ammonia electrosynthesis from nitrate using a stable amorphous/crystalline dual-phase Cu catalyst by Yi Wang, Shuo Wang, Yunfan Fu, Jiaqi Sang, Pengfei Wei, Rongtan Li, Dunfeng Gao, Guoxiong Wang, Xinhe Bao

    Published 2025-01-01
    “…The impressive electrocatalytic performance is ascribed to the presence of stable amorphous Cu domains which promote the adsorption and hydrogenation of nitrogen-containing intermediates, thus improving reaction kinetics for ammonia formation. …”
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  16. 5836

    Acute effect of exercise with or without the integration of cooperative activities on inhibitory control in preadolescent school children by Melanie Berger, Markus Gerber, Sebastian Ludyga

    Published 2025-01-01
    “…Do different cognitive domains mediate the association between moderate‐to‐vigorous physical activity and adolescents’ off‐task behaviour in the classroom? …”
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  17. 5837

    Painting a portrait: Analysis of national health survey data for cancer genetic counseling by Monica H. Stamp, Ora K. Gordon, Christopher P. Childers, Kimberly K. Childers

    Published 2019-03-01
    “…Abstract Background Despite a growing body of literature describing the geographic and sociodemographic distribution of cancer genetic testing, work focused on these domains in cancer genetic counseling is limited. Research describing the epidemiology of cancer genetic counseling has mainly focused on isolated populations, a single gender (women) and a single condition (hereditary breast and ovarian cancer). …”
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  18. 5838

    Facilitators and barriers to reach and enrollment into a medically tailored meals program within a section 1115 Medicaid pilot: clinic staff perspectives by Sara C. Folta, Jessica Burch, Matthew Alcusky, Arlene S. Ash, Kurt Hager, Jean Terranova, Fang Fang Zhang, Oyedolapo Anyanwu, Zhongyu Li, Dariush Mozaffarian

    Published 2025-02-01
    “…The study team identified and discussed common themes and presented them back to our ACO partners.ResultsStaff described facilitators of and barriers to reach and enrollment related to several domains of the Health Equity Implementation Framework. …”
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  19. 5839

    Employee retention through effective human resource management practices in Maldives: Mediation effects of compensation and rewards system by Zubair Hassan

    Published 2022-01-01
    “…This study contributes to developing new knowledge in the theoretical domains of HRM practices. In particular, the findings of the study strengthen Hertzberg‘s Two-Factor theory by confirming that career growth opportunities, advancement and salary significantly determine employee retention. …”
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  20. 5840

    Predictors of long-term symptom burden and quality of life in patients hospitalised with chest pain: a prospective observational study by Tone Merete Norekvål, Jørund Langørgen, Torbjørn Omland, Øyvind Skadberg, Kjell Vikenes, Nasir Saeed, Ole-Thomas Steiro, Hilde Lunde Tjora, Rune Oskar Bjørneklett, Vernon Vijay Singha Bonarjee, Øistein Rønneberg Mjelva, Kristin Moberg Aakre

    Published 2022-07-01
    “…NSTEMI and UAP patients who were revascularised reported higher scores (p&lt;0.05) in SAQ-7-QL, SAQ7-PL, SAQ7-summary (NSTEMI) and all SAQ-7 domains (UAP). Revascularisation altered the unstandardised beta value (&gt;±10%) of an UAP diagnosis for all SAQ-7 and RAND-12 outcomes.Conclusions Patients with NSTEMI reported the most favourable outcome 3 months after hospitalisation for chest pain. …”
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