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5801
Accuracy of Large Language Models for Infective Endocarditis Prophylaxis in Dental Procedures
Published 2025-02-01“…Pre-prompts offer a potential solution, and domain-specific training is essential for optimizing LLM performance in healthcare, especially with the emergence of models with increased token limits.…”
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5802
Optic Nerve Head Hemoglobin Levels in Glaucoma: A Structural and Functional Correlation Study
Published 2021-01-01“…All participants underwent visual field (VF) testing (standard automated perimetry, SAP), color fundus imaging (mydriatic retinography), and peripapillary retinal nerve fiber layer (pRNFL) assessment through spectral-domain optical coherence tomography (SD-OCT). Software Laguna ONhE was used to estimate the amount of ONH Hb and to determine the glaucoma discriminant function (GDF) index. …”
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5803
Caregiver Global Impression Observations from EMBARK: A Phase 3 Study Evaluating Delandistrogene Moxeparvovec in Ambulatory Patients with Duchenne Muscular Dystrophy
Published 2024-11-01“…Data were evaluated using multi-domain responder index (MDRI) and ordinal regression analyses. …”
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5804
Corticosteroid Phobia: A Key Barrier to Treatment in Young Women with Idiopathic Granulomatous Mastitis
Published 2025-01-01“…IGM patients with systemic symptoms were associated with higher scores in the behavior domain and/or global TOPICOP. Young, low educated, and unemployed individuals were more likely to have corticosteroid phobia (p < 0.05). …”
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5805
ECG-LM: Understanding Electrocardiogram with a Large Language Model
Published 2025-01-01“…Methods: Although recent advancements in multi-modal large language modeling have propelled their application scope beyond the natural language processing domain, their applicability to ECG processing remains largely unexplored, partly due to the lack of text–ECG data. …”
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5806
Structural reversal of disc cupping measured in Bruch’s membrane opening-based OCT morphometry after PRESERFLO microshunt implantation for open-angle glaucoma
Published 2025-01-01“…Longitudinal change in morphometric spectral domain OCT parameters of the ONH was correlated to change in IOP. …”
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5807
Mapping Susceptibility and Risk of Land Subsidence by Integrating InSAR and Hybrid Machine Learning Models: A Case Study in Xi'an, China
Published 2025-01-01“…It further found that the groundwater level and its changes are the domain factors in Xi'an from machine learning method. …”
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5808
Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
Published 2023-01-01“…Mechanistic studies were performed using single-cell RNA-sequencing.Results Applying stringent in vitro assays and orthotopic in vivo NB models, we demonstrated that our single-chain variable fragment, CT3, integrated into a CAR vector with a CD28 hinge, CD28 transmembrane, and 4-1BB co-stimulatory domain (CT3.28H.BBζ) elicits the best preclinical anti-NB activity compared with other tested CAR constructs. …”
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5809
Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Products
Published 2025-01-01“…Historically, RWE studies have been the domain of prescription drugs, driven by the fact that clinical data on patients are routinely captured in medical records, claims databases, registries, etc. …”
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5810
Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers
Published 2025-01-01“…ABSTRACT Background SET domain‐containing protein 4 (SETD4) is a histone methyltransferase that has been shown to modulate cell proliferation, differentiation, and inflammatory responses by regulating histone H4 trimethylation (H4K20me3). …”
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5811
Analog parallel processor for broadband multifunctional integrated system based on silicon photonic platform
Published 2025-02-01“…Here, we report an analog parallel processor (APP) based on the silicon photonic platform that directly discretizes and parallelizes the broadband signal in the analog domain. The APP first discretizes the signal with the optical frequency comb and then adopts optical dynamic phase interference to reassign the analog signal into 2N parallel sequences. …”
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5812
Navigating the future of agri-food supply chain: A conceptual framework using bibliometric review
Published 2025-03-01“…Microsoft Excel and VOSviewer were used for an in-depth analysis of prolific authors, article trends, institutions, countries, influential articles, and source titles within the domain of AFSC. Co-occurrence analysis was conducted to identify seven core research themes, namely: agri-food supply chain system; agri-food supply chain management; agri-food supply chain industry; agri-food supply chain risk factors; agri-food supply chain information; agri-food supply chain advancement; agri-food supply chain risk management; This study makes a significant contribution by constructing a comprehensive conceptual framework that logically organizes these thematic factors, aligning future research with emerging trends. …”
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5813
Computational insights into Sitahe (Leuconotis eugenifolia) bioactive compounds: A promising approach for radioprotection through p53 inhibition
Published 2025-01-01“…Molecular docking studies identified strong binding affinities between these compounds and the p53 DNA binding domain, with baurenol demonstrating the highest binding affinity at −6.75 kcal/mol, which is better compared to rhazinilam (−4.55 kcal/mol), leuconolam (−4.36 kcal/mol), leuconoxine (−4.26 kcal/mol), and dehydroleuconoxine (−4.76 kcal/mol). …”
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5814
The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome
Published 2024-12-01“…Recent studies highlight the significant role of inflammation involved in ALI/ARDS, particularly the hyperactivation of the NOD‐like receptor thermal protein domain‐associated protein 3 (NLRP3) inflammasome in macrophages. …”
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5815
GWAS identifies a polyembryony locus in mango: development of KASP and PACE markers for marker-assisted breeding
Published 2025-01-01“…This locus contains the MiRWP/MiRKD4 gene, which codes for an RWP–RK domain-containing protein previously implicated in citrus apomixis. …”
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5816
A Heterogeneously Integrated 256-Element 5G Phased Array: Design, Assembly, Test
Published 2025-01-01“…The paper also covers, in detail, several practical aspects of phased array module design that are not well-described in existing literature, such as power domain modeling, module assembly, antenna feedline design, polarization isolation, and tile spacing. …”
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5817
Health-Related Quality of Life, Treatment Satisfaction, Adherence and Persistence in β-Thalassemia and Myelodysplastic Syndrome Patients with Iron Overload Receiving Deferasirox: R...
Published 2012-01-01“…Compared to age-matched norms, β-thalassemia and MDS patients reported lower SF-36 domain scores at baseline. Low levels of treatment satisfaction, adherence, and persistence were also observed. …”
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5818
Protective Effects of Baicalein on Lipopolysaccharide-Induced AR42J PACs through Attenuation of Both Inflammation and Pyroptosis via Downregulation of miR-224-5p/PARP1
Published 2024-01-01“…The RNA and protein expression of miR-224-5p, poly ADP-ribose polymerase-1 (PARP1), nuclear transcription factor-κB65 (NF-κB65), phospho-kappa B alpha(p-IκB-α), interleukin(IL)-18R, NOD-like receptor thermal protein domain-associated protein 3 (NLRP3), gasdermin D (GSDMD), apoptosis-associated speck-like protein containing a CARD (ASC), and caspase-1 was detected based on the WB and RT-PCR assays. …”
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5819
Mapping knowledge landscapes and emerging trends in artificial intelligence for antimicrobial resistance: bibliometric and visualization analysis
Published 2025-01-01“…Key bibliometric indicators including co-authorship patterns, keyword co-occurrence, and citation impact were analyzed to delineate research evolution and collaboration patterns in this domain.ResultsA collection of 2,408 publications was analyzed, demonstrating significant annual growth with publications increasing from 4 in 2014 to 549 in 2023 (22.7% of total output). …”
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5820
Compact Quantum Cascade Laser-Based Noninvasive Glucose Sensor Upgraded with Direct Comb Data-Mining
Published 2025-01-01“…Specifically, the sensor performance is validated with 492 glucose absorption scans in the time domain, each with 20 million datapoints measured from four subjects with glucose concentrations of 3.9–7.9 mM. …”
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