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5781
Advances in Radiation Protection in Oral and Dental Radiology: Pragmatic Approaches and Recent Innovations
Published 2025-01-01“…Given the increasing frequency of dental CBCT imaging and the unmatched dose levels compared to conventional dental radiography, it is imperative to set DRLs in this domain. Conclusion: This literature review focuses on the most common types of radiation protection in dental radiology, aiming to demonstrate improved techniques for individual protection. …”
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5782
Predicting the impact of missense mutations on an unresolved protein’s stability, structure, and function: A case study of Alzheimer’s disease-associated TREM2 R47H variant
Published 2025-01-01“…We first demonstrated that the predicted structure retained a high accuracy in critical regions of the extracellular domain and subsequently validated the in-silico mutagenesis methods by evaluating the effects of the strongest risk variant R47H of TREM2. …”
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5783
A Novel Convolutional Neural Network-Based Approach for Fault Classification in Photovoltaic Arrays
Published 2020-01-01“…Unlike contemporary work, five different faulty cases (including faults in PS – on which no work has been done before in the machine learning domain) have been considered in our study, along with the incorporation of MPPT. …”
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5784
The role of the hippocampus in working memory and word reading: Novel neural correlates of reading among youth living in the context of economic disadvantage
Published 2025-01-01“…A hippocampal circuit is one likely candidate, as it has recently been shown to support domain-general processes like working memory (WM) that are also associated with reading. …”
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5785
Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro
Published 2025-02-01“…A new mutation in the domain V region of 23S rRNA gene (C2404T) and one mutation in amino acid sequences of ribosomal protein (Met208Thr) were firstly identified among linezolid-resistant strains. …”
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5786
Is Rhodamine 123 an Appropriate Fluorescent Probe to Assess P-Glycoprotein Mediated Multidrug Resistance in Vinblastine-Resistant CHO Cells?
Published 1997-01-01“…This cell line (CHOVBR) displays high reactivity with a monoclonal antibody (MAb) (C219) directed against an internal domain of P‐gp, and an active Rho123 efflux, as shown by parallel flow cytometric and fluorometric assays. …”
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5787
A novel strategy for the protective effect of ginsenoside Rg1 against ovarian reserve decline by the PINK1 pathway
Published 2025-12-01“…Molecular docking analysis revealed that the ginsenoside Rg1 could bind to the active site of the PINK1 kinase domain.Discussion and conclusions Ginsenoside Rg1 targets PINK1 to regulate mitophagy, preserving ovarian reserve. …”
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5788
Improving polyketide biosynthesis by rescuing the translation of truncated mRNAs into functional polyketide synthase subunits
Published 2025-01-01“…The truncated mRNA translation rescue strategy will facilitate engineering of multi-domain proteins to enhance their functions.…”
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5789
A synthetic cyclic peptide for promoting antigen presentation and immune activation
Published 2025-01-01“…., bovine serum albumin [BSA], receptor binding domain (RBD) of the SARS-CoV-2 protein responsible for COVID-19 infection [SARS-CoV-2 RBD]) and small molecular haptens (e.g., cocaine). …”
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5790
L’agriculture itinérante sur brûlis, une menace sur la forêt tropicale humide ?
Published 2012-11-01“…(Kleinman et al. 1995).In the context of the announcement of the creation of the National Park of the South of French Guiana, an interdisciplinary program (ecology, pedobiology, ethnology; MNHN-CNRS-IRD) Effects of the traditional cultural practices on soils and forest (French Environment Ministry) studied the effects of the itinerant agriculture on slash-and-burn field from an analysis of the conditions which allow Amerindian communities to satisfy their material and spiritual needs in a forest system.This program set up the following points:– the fine practices of this agriculture, constituting a real strategy, supply efficiently the mineral elements in the cultures, without purchase of fertilizers, and ensure a rapid forest recovery after at least 10 years; the cycles short culture - long fallow allow the self regeneration of an agroforestry system registered since millenniums in the forest dynamics of the river banks;– the adoption of the long fallow limits the spatial extent of every family to 10-15 hectares at most;– the transportation on foot of the harvest towards the village limits the extent of the agriculture to a 3-4 km band from the river; beyond, the forest is protected from an agricultural pressure;– the absence of the market does not lead to an increase of the cultivated surfaces and the pressure on the forest is not increasing thus at present;– the forest of the hinterland includes wide zones restricted by strong social taboos; the conservation of the social organization of the Amerindian ethnic groups is the first condition of the preservation of the forest domain.The real solution for the preservation of the forest heritage in the South of French Guiana, obviously social, was thus already political, before the creation of the “Amazonian Park of Guyana” (2007).…”
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5791
Human inborn errors of immunity underlying Talaromyces marneffei infections: a multicenter, retrospective cohort study
Published 2025-01-01“…One patient was diagnosed with caspase-recruitment domain (CARD9) deficiency due to a compound mutation in the CARD9 gene, while another patient was confirmed with adenosine deaminase (ADA) deficiency.ConclusionT. marneffei infections in children with IEIs induced severe systemic complications. …”
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5792
Role of Fcγ receptors in HER2-targeted breast cancer therapy
Published 2022-01-01“…An example of an approved anti-HER2 Fc-engineered chimeric mAb is margetuximab, which targets the same epitope as trastuzumab, but features five amino acid substitutions in the IgG 1 Fc domain that were deliberately introduced to increase binding to activating FcγRIIIa and decrease binding to inhibitory FcγRIIb (CD32B). …”
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5793
Splicing and expression dynamics of SR genes in hot pepper (Capsicum annuum): regulatory diversity and conservation under stress
Published 2025-01-01“…Interestingly, a cross-species comparative study with Arabidopsis (Arabidopsis thaliana) and tomato (Solanum lycopersicum) showed that many AS events impact the region which codes the RNA recognition motif (RRM) domain of the protein, indicating a conserved regulatory mechanism of SR proteins in plants. …”
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5794
DR Loss-Free Dithering-Based Digital Background Linearity Calibration for SAR-Assisted Multi-Stage ADCs With Digital Input-Interference Cancellation
Published 2024-01-01“…In addition, a digital-domain input-interference cancellation (IIC) technique is proposed to accelerate the convergence speed of the correlation-based calibration. …”
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5795
Smart Pharmaceutical Monitoring System With Personalized Medication Schedules and Self-Management Programs for Patients With Diabetes: Development and Evaluation Study
Published 2025-02-01“…As new technologies, artificial intelligence and digital technologies are covering all aspects of the medical and health care field, but their application and evaluation in the domain of diabetes research remain limited. …”
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5796
Development of data-driven algal bloom alert models with low temporal resolution data and application to Hong Kong rivers
Published 2025-02-01“…This study offers a potential solution for prediction and forecasting without extensive datasets and emphasizes the importance of integrating domain knowledge in both prior and posterior analyses to enhance the interpretability of data-driven models in water science.…”
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5797
The science and politics of ‘knowledge’ in safe sport research
Published 2025-01-01“… Research in the domain of safe sport frequently focuses on prevalence studies that have been historically dissimilar in methodology. …”
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5798
Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis
Published 2020-12-01“…The evolutionary changes observed in the inserted 23 amino acids in the RNA binding domain (RBD) of the coronvirus spike glycoprotein which cannot be detected in any other human coronavirus. …”
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5799
Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer
Published 2025-02-01“…Functional assays demonstrated that circPCDH11Y plays a role in regulating the expression of key neuroendocrine markers, including synaptophysin (SYP), neuron-specific enolase (ENO2), prostate-specific antigen (PSA), Brain-Specific Homeobox/POU Domain Protein 2 (BRN2) and the linear form of Protocadherin 11 Y-Linked (PCDH11Y). …”
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5800
Toward Integrating ChatGPT Into Satellite Image Annotation Workflows: A Comparison of Label Quality and Costs of Human and Automated Annotators
Published 2025-01-01“…A set of satellite images is annotated by a domain expert and 15 additional human and automated annotators, differing in expertise and costs. …”
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