Scavenger Receptor Class B, Type I, a CD36 Related Protein in Macrobrachium nipponense: Characterization, RNA Interference, and Expression Analysis with Different Dietary Lipid Sou... by Zhili Ding, Na Luo, Youqin Kong, Jingfen Li, Yixiang Zhang, Fang Cao, Jinyun Ye

“…The MnSR-BI primary structure consisted of a CD36 domain that contained two transmembrane regions at the N- and C-terminals of the protein. …”
Get full text

Evaluation of IgG binding capability to SARS-CoV-2 variants in early COVID-19 convalescent sera using an indirect ELISA by Behzad Hussain, Peizhe Zhao, Yu Liu, Bo Yang, Xiaoxiong Li, Zhichao Zhang, Guoqiang Feng, Demei Zhang, Defen Lu, Wu Changxin

“…SARS-CoV-2 has been mutating rapidly resulting in the emergence of multiple variants to escape the host immune system mainly by mutations in its receptor binding domain (RBD) of the spike protein. The RBD and full-length spike of SARS-CoV-2 are the main targets of the neutralizing antibodies (mainly IgGs). …”
Get full text

Side-Stream Based Marine Solubles From Atlantic Cod (Gadus morhua) Modulate Appetite and Dietary Nutrient Utilization in Atlantic Salmon (Salmo salar L.) and can Replace Fish Meal by Hanne Jorun Sixten, Ivar Rønnestad, André S. Bogevik, Tone Aspevik, Åge Oterhals, Ana S. Gomes, Floriana Lai, Ingvill Tolås, Virginie Gelebard, Marie Hillestad, Katerina Kousoulaki

“…Expression of stomach ghrelin-1 (ghrl1) was higher than ghrelin-2 (ghrl2) and membrane-bound O-acyltransferase domain-containing 4 (mboat4), and midgut peptide YYa-2 (pyya2) and glucagon-a (gcga) were higher than peptide YYb-1 (pyyb1). …”
Get full text

Antibody Avidity and Neutralizing Response against SARS-CoV-2 Omicron Variant after Infection or Vaccination by Francesca Dapporto, Serena Marchi, Margherita Leonardi, Pietro Piu, Piero Lovreglio, Nicola Decaro, Nicola Buonvino, Angela Stufano, Eleonora Lorusso, Emilio Bombardieri, Antonella Ruello, Simonetta Viviani, Eleonora Molesti, Claudia Maria Trombetta, Alessandro Manenti, Emanuele Montomoli

“…This study aimed at investigating the avidity of receptor-binding domain (RBD) binding antibodies and their neutralizing activity against the Omicron variant in SARS-CoV-2 infected patients and vaccinees. …”
Get full text

C3-VQA: Cryogenic Counter-Based Coprocessor for Variational Quantum Algorithms by Yosuke Ueno, Satoshi Imamura, Yuna Tomida, Teruo Tanimoto, Masamitsu Tanaka, Yutaka Tabuchi, Koji Inoue, Hiroshi Nakamura

“…Based on the workload analysis and domain-specific system design focused on variational quantum algorithms (VQAs), we propose the cryogenic counter-based coprocessor for VQAs (C3-VQA) to enhance the design scalability of cryogenic quantum computers under the thermal constraint. …”
Get full text

Differential impacts of water diversion and environmental factors on bacterial, archaeal, and fungal communities in the eastern route of the South-to-North water diversion project by Moran Tang, Qian Chen, Xinzong Xiao, Yitao Lyu, Weiling Sun

“…Despite their importance, the impacts of such projects on multi-domain microbial community dynamics and the underlying mechanisms remain poorly understood. …”
Get full text

Osmanlı’dan Cumhuriyet’e İstanbul’da Esrar Tekkeleri by Asaf Özkan, Rıdvan Kızılkaya

“…Türkiye’de 1933 yılına kadar afyon ve türevleri olan maddeler -eroin, morfin, kokain- gibi esrarın da üretimi, ticareti ve kullanımına yönelik herhangi bir yasak olmadığı için serbestçe satışı yapılmıştır. …”
Get full text

Comprehensive identification, characterization and expression analyses of the class III POD gene family in water lily (Nymphaea colorata) by Wasi Ullah Khan, Wasi Ullah Khan, Latif Ullah Khan, Noor Muhammad Khan, Ji Zhang, Wang Wenquan, Wang Wenquan, Fei Chen, Fei Chen

“…In this study, 94 NcPOD genes in water lily were identified, each possessing a conserved POD domain, which are dispersed unevenly across the genome. …”
Get full text

Large language models generating synthetic clinical datasets: a feasibility and comparative analysis with real-world perioperative data by Austin A. Barr, Joshua Quan, Eddie Guo, Emre Sezgin, Emre Sezgin

“…Recent advances in large language models (LLMs) provide an opportunity to generate synthetic data with reduced reliance on domain expertise, computational resources, and pre-training.ObjectiveThis study aims to assess the feasibility of generating realistic tabular clinical data with OpenAI’s GPT-4o using zero-shot prompting, and evaluate the fidelity of LLM-generated data by comparing its statistical properties to the Vital Signs DataBase (VitalDB), a real-world open-source perioperative dataset.MethodsIn Phase 1, GPT-4o was prompted to generate a dataset with qualitative descriptions of 13 clinical parameters. …”
Get full text

The Role of Caspase-4 and NLRP1 in MCF7 Cell Pyroptosis Induced by hUCMSC-Secreted Factors by Yang Jiao, Linlin Wang, Lin Lu, Jianjun Liu, Xin Li, Hongbo Zhao, Zongliu Hou, Bingrong Zheng

“…Our previous study showed that the factors secreted by human umbilical cord MSCs (hUCMSCs) induced pyroptosis in the breast cancer cell line MCF7 and our RNA sequencing studies revealed an increase in the expression of the pyroptosis-related gene caspase-4 (CASP4) and nucleotide-binding, leucine-rich repeat pyrin domain-containing protein 1 (NLRP1) in pyroptotic MCF7 cells. …”
Get full text

Caractérisation éthologique de l’émotivité chez le cercopithèque de Brazza (Cercopithecus neglectus) by Helene Meunier, Philippe Bec, Catherine Blois-Heulin

“…., 1994). But emotivity domain is complex; it includes, among others, both aspects of gregariousness (Kilgour, 1975 ; Jones, 1977, 1987) and neophobia. …”
Get full text

Meta-analysis of the accuracy for RASSF1A methylation in bronchial aspirates for the diagnosis of lung cancer. by Xu-Ping Chen, Shi-Xu He, Meng-You Chen, Fu-Bin Chen, Peng Wu, Ping Shi, Shi-Cai Zhao, Ling-Yan Zhao, Xiao-Min Xiong, Jia Zeng

“…<h4>Objective</h4>To establish the diagnostic accuracy of RASSF1A (Ras association domain family 1 isoform) methylation using bronchial aspirates as an auxiliary method for diagnosing lung cancer through a systematic review and meta-analysis.…”
Get full text

Gedunin Mitigates <i>Cutibacterium acnes</i>-Induced Skin Inflammation by Inhibiting the NF-κB Pathway by Ju Kyoung Sim, Ye Ji Heo, Jin Hak Shin, Seon Sook Kim, Su Ryeon Seo

“…Mechanistic studies focused on the nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways, along with the NOD-like receptor pyrin domain-containing 3 (NLRP3) inflammasome. An in vivo acne model was employed to examine gedunin’s therapeutic efficacy. …”
Get full text

Harmonic and Supra-Harmonic Emissions of Electric Vehicle Chargers: Modeling and Cumulative Impact Indices by Antonio Bracale, Pierluigi Caramia, Giovanni Mercurio Casolino, Pasquale de Falco, Iqrar Hussain, Pietro Varilone, Paola Verde

“…The methodology accounts for variables such as EV charging powers, upstream network impedance, and number of EVs. A simplified time-domain model of a low-power unidirectional converter, commonly used for EV battery charging, is employed to balance circuit complexity and computational effort. …”
Get full text

The Evaluation of Change in Psychosocial Risk With Caregivers of Children With Chronic Kidney Disease: A Short-term Longitudinal Mixed-Methods Study by Caroline C. Piotrowski, Kira Kudar, Julie Strong, Ashley Giesbrecht, Anne Kazak, Katerina Pappas, Gina Rempel, Aviva Goldberg

“…Results: Quantitatively, overall family psychosocial risk scores increased significantly during the pandemic health emergency, as did the domain of Caregiver Problems. Families of transplant recipients were found to be at significantly lower psychosocial risk pre-pandemic than families of transplant candidates. …”
Get full text

The members of zinc finger-homeodomain (ZF-HD) transcription factors are associated with abiotic stresses in soybean: insights from genomics and expression analysis by Hafiz Muhammad Rizwan, Jiayi He, Muhammad Nawaz, Keyu Lu, Mingfu Wang

“…All GmZF-HD genes contained a conserved ZF-HD_dimer domain and had diverse physicochemical features. Furthermore, the GmZF-HD gene structures exhibited 3 to 10 conserved motifs, and most of them showed intronless gene structures. …”
Get full text

Review: Livestock cell types with myogenic differentiation potential: Considerations for the development of cultured meat by M. Olenic, C. Deelkens, E. Heyman, E. De Vlieghere, X. Zheng, J. van Hengel, C. De Schauwer, B. Devriendt, S. De Smet, L. Thorrez

“…This review focuses on a pivotal aspect of the cellular agriculture domain: cells. We summarised information on the various cell types from farm animals currently used for the development of cultured meat, including mesenchymal stromal cells, myoblasts, and pluripotent stem cells. …”
Get full text

The Geographical Distribution of Global Biobanks by Farzad Parvizpour, Sarvenaz Salahi, Mohammad Amin Mahmanzar, Karim Rahimian, Neda Esfandiari, Zahra Fatahi, Niousha Khoshdast, Reyhaneh Yarmohammadi, Mohamad Amir Amirkhani, Arefeh Jafarian

“…UnitedKingdom (n=78, P=43.09%), Canada (n=43, P=23.75%), and the United States (n=33, P=18.23%) were the countrieswith a higher frequency of tissue-based biobanks (domain frequency: 1-78; 0.55-43.09%). However, tissue and genebasedbiobanks had the most minor frequency and were only in two countries of Spain (n=1, P=25%) and the UnitedKingdom (n=3, P=75%). …”
Get full text

Surrogate-based model parameter optimization in simulations of the West African monsoon by M. Fischer, P. Knippertz, C. Proppe

“…However, a lower entrainment parameter would lead to a more accurate simulation of accumulated precipitation, averaged 2 <span class="inline-formula">m</span> dew point temperature, and mean sea level pressure over the considered domain (15° W to 15° E, 0 to 25° N). An improvement in 2D output fields instead of QoIs is barely possible with the considered parameters, which confirms meaningful default values of the model parameters for the region. …”
Get full text

Repurposing brucine as a chemopreventive agent in mammary gland carcinoma: Regulating lactate transport through MCT-4 by Asma Khatoon Zaidi, Anurag Kumar, Rohit Kumar, Jyoti Singh, Sneha Yadav, Archana Bharti Sonkar, Dharmendra Kumar, Neeraj Kumar Shrivastava, Mohd Nazam Ansari, Abdulaziz S. Saeedan, Gaurav Kaithwas

“…BRU demonstrated strong affinity for the MCT-4 transporter's catalytic domain, forming significant hydrophobic and polar interactions with essential amino acids at the binding site. …”
Get full text