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5621
Benefits of the Global Integration Method (Método de Integração Global - MIG) in functional priorities of parents of Brazilian children and adolescents with autism spectrum disorde...
Published 2025-01-01“…Approximately 64% of the priorities were classified in the activity domain of the ICF. In general, the MIG program resulted in significant improvements in performance and satisfaction for the majority of functional priorities (p < 0.05). …”
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5622
Improved Performance and Voltage Stability of Islanded Inverters Using Single-Loop PI-Lead Controller
Published 2025-01-01“…Despite the challenges posed by multi-resonance phenomena and coupling effects inherent in single-loop SRF-based modeling, a comprehensive frequency-domain analysis is performed, with systematic controller parameter design guidelines to mitigate multi-gain crossover issues. …”
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5623
Understanding Individual Differences in Happiness Sources and Implications for Health Technology Design: Exploratory Analysis of an Open Dataset
Published 2025-01-01“…The science of happiness is one such domain that holds significant applied importance due to its links to well-being and evidence that happiness can be cultivated through interventions. …”
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5624
Association between intraoperative fluid management and postoperative outcomes in living kidney donors: a retrospective cohort study
Published 2025-01-01“…Abstract Optimal fluid strategy for laparoscopic donor nephrectomy (LDN) remains unclear. LDN has been a domain for liberal fluid management to ensure graft perfusion, but this can result in adverse outcomes due to fluid overload. …”
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5625
Prediction of Groundwater Level Based on the Integration of Electromagnetic Induction, Satellite Data, and Artificial Intelligent
Published 2025-01-01“…The results showed that the RS_GWL prediction model explains 30% and 90% of the spatial variability in the two value domain intervals, GWL < 10 m and GWL > 10 m, respectively. …”
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5626
Evaluation of Navigated Laser Photocoagulation (Navilas 577+) for the Treatment of Refractory Diabetic Macular Edema
Published 2018-01-01“…Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (OCT) parameters were measured at baseline, 1, 3, and 6 months, and final visit. …”
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5627
The Feasibility of Telephone-delivered Self-management Intervention in Multiple Sclerosis
Published 2025-01-01“…It also influenced the quality-of-life total score (P=0.049) and mental health domain (P=0.018). Conclusion: Telephone-delivered self-management intervention in patients with MS has positive effects in many of the investigated areas, and this intervention can be used to improve the quality of life of these patients.…”
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5628
High Glucose Induces Endothelial COX2 and iNOS Expression via Inhibition of Monomethyltransferase SETD8 Expression
Published 2020-01-01“…Our previous study indicated that SET domain-containing protein 8 (SETD8) downregulation is involved in high glucose-mediated endothelial inflammation in human umbilical vein endothelial cells (HUVECs). …”
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5629
Satellite-based Emission Inventory Adjustments Improve Simulations of Long-range Transport Events
Published 2021-09-01“…Abstract Long-range pollution transport (LRT) events have a wide impact across East Asia, but are often difficult to track due to imprecise emission inventories and changing domain scales as the plume moves from source to receptor locations. …”
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5630
A Semianalytical Model for Analyzing the Infill Well-Caused Fracture Interference from Shale Gas Reservoirs
Published 2021-01-01“…The approximate expressions for different flow regimes are used in making production predictions in the time domain, and a flowing material balance method and a simple iteration are used to update the model parameters step by step. …”
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5631
TACSTD2 in gelatinous drop-like corneal dystrophy: variant functional analysis and expression in the cornea after limbal stem cell transplantation
Published 2024-07-01“…Functional analysis in a cell model system revealed the loss of the transmembrane domain and subcellular protein mislocalization. The patient with GDLD underwent direct allogeneic LSCT with epithelial debridement followed by deep anterior lamellar keratoplasty 10 months later due to amyloid deposition and deterioration of vision. …”
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5632
Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification
Published 2025-01-01“…Results were compared to AD-relevant regions to measure adherence to domain knowledge. Then, differences in explainability patterns between the two models were assessed to explore the insights offered by each piece of data (i.e., MRI vs. connectivity). …”
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5633
Using Large Language Models to Detect and Understand Drug Discontinuation Events in Web-Based Forums: Development and Validation Study
Published 2025-01-01“…We provide an example of the utility of this framework by identifying DDEs and their root causes in an open-source web-based forum, MedHelp, and by releasing the first open-source DDE datasets to aid further research in this domain. MethodsWe used several LLMs, including GPT-4 Turbo, GPT-4o, DeBERTa (Decoding-Enhanced Bidirectional Encoder Representations from Transformer with Disentangled Attention), and BART, among others, to detect and determine the root causes of DDEs in user comments posted on MedHelp. …”
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5634
Phosphorylation-dependent WRN-RPA interaction promotes recovery of stalled forks at secondary DNA structure
Published 2025-01-01“…We identify several conserved phosphorylation sites in the acidic domain of WRN targeted by Casein Kinase 2. These phosphorylation sites are crucial for WRN-RPA interaction. …”
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5635
High-Affinity Anti-VISTA Antibody Protects against Sepsis by Inhibition of T Lymphocyte Apoptosis and Suppression of the Inflammatory Response
Published 2021-01-01“…B7 family members and ligands have been identified as critical checkpoints in orchestrating the immune response during sepsis. V-domain Ig suppressor of T cell activation (VISTA) is a new inhibitory immune checkpoint involved in restraining T cell response. …”
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5636
The Calicophoron daubneyi genome provides new insight into mechanisms of feeding, eggshell synthesis and parasite-microbe interactions
Published 2025-01-01“…Results Several gene families have undergone specific expansion in C. daubneyi, including the peptidoglycan-recognition proteins (PGRPs) and DM9 domain-containing proteins, which function as pattern-recognition receptors, as well as the saposin-like proteins with putative antibacterial properties, and are upregulated upon arrival of the fluke in the microbe-rich rumen. …”
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5637
Macular Pigment Optical Density in Chinese Primary Open Angle Glaucoma Using the One-Wavelength Reflectometry Method
Published 2016-01-01“…Two parameters, max and mean optical density (OD), were used for analyses. Spectral-domain-optical coherence tomography was used to measure retinal thickness, including central retinal thickness (CRT), the macular ganglion cell complex (GCC), and the circumpapillary retinal nerve fiber layer (RNFL). …”
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5638
Nuclear farnesoid X receptor protects against bone loss by driving osteoblast differentiation through stabilizing RUNX2
Published 2025-01-01“…The interaction between RUNX2 and Thoc6 was mediated by the Runt domain of RUNX2 and the WD repeat of Thoc6. Additionally, Obeticholic acid (OCA), an orally available FXR agonist, could ameliorate bone loss in an ovariectomy (OVX)-induced osteoporotic mouse model. …”
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5639
Mapping the landscape of Hospital at home (HaH) care: a validated taxonomy for HaH care model classification
Published 2025-01-01“…Taxonomies serve as classification systems that simplify complexity and enhance understanding within a specific domain. Objective This paper introduces a comprehensive taxonomy of HaH care models, aiming to categorize and compare the various ways HaH services are delivered as an alternative to traditional hospital care. …”
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5640
Physically Meaningful Surrogate Data for COPD
Published 2024-01-01“…To ensure the faithfulness of our domain-aware COPD surrogates, the generated waveforms are examined through both flow waveforms and photoplethysmography (PPG) waveforms (as a proxy for intrathoracic pressure) in terms of duty cycle, sample entropy, FEV<sub>1</sub>/FVC ratios and flow-volume loops. …”
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