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5201
YAP/TAZ-associated cell signaling – at the crossroads of cancer and neurodevelopmental disorders
Published 2025-01-01“…YAP/TAZ (Yes-associated protein/paralog transcriptional co-activator with PDZ-binding domain) are transcriptional cofactors that are the key and major downstream effectors of the Hippo signaling pathway. …”
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5202
Whole-Genome Duplication and Purifying Selection Contributes to the Functional Redundancy of Auxin Response Factor (ARF) Genes in Foxtail Millet (Setaria italica L.)
Published 2021-01-01“…SiARFs clustered within the same clade shared similar gene structure and protein domain composition, implying functional redundancy. …”
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5203
Switch of Intravitreal Therapy for Macular Edema Secondary to Retinal Vein Occlusion from Anti-VEGF to Dexamethasone Implant and Vice Versa
Published 2017-01-01“…Outcome parameters were change in best-corrected visual acuity (BCVA) and central foveal thickness (CFT) measured by spectral-domain optical coherence tomography. Results. Mean BCVA improvement after switch to dexamethasone implant was 4 letters (p=0.08), and treatment naïve eyes gained 10 letters (p=0.66), while we noted no change in eyes after switch to anti-VEGF (p=0.74). …”
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5204
The Observance of Patient Rights in the Emergency Departments of Hospitals in Golestan Province, Iran
Published 2024-06-01“…The rate of observance based on the nurses’ perceptions was higher than that based on patients’ perceptions (75.6% with a mean of 3.72±0.29 vs. 74.88% with a mean of 3.80±0.17), but it was not statistically significant (P= 0.31). In the domain of “priority of patients’ comfort”, the rate of observance based on the perceptions of nurses was significantly higher (P=0.04). …”
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5205
Exact controllability for systems describing plate vibrations. A perturbation approach
Published 2024-05-01“…When applied to systems described by the classical Kirchhoff equations, our abstract results, combined with some elliptic Carleman-type estimates, yield exact controllability in arbitrarily small time, provided that the system described by the wave equation in the same spatial domain and with the same control operator is exactly controllable. …”
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5206
Evidence of Presynaptic Localization and Function of the c-Jun N-Terminal Kinase
Published 2017-01-01“…By means of modelling design, we found that JNK, via the JBD domain, acts as a physiological effector on T-SNARE proteins; then using biochemical approaches we demonstrated the interaction between Syntaxin-1-JNK, Syntaxin-2-JNK, and Snap25-JNK. …”
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5207
Insights into the binding selectivity of harzianoic acids A and B to tetraspanin CD81
Published 2023-11-01“…Key H-bonds between the acid groups of Hz-B and the CD81-LEL domain stabilize the ligand-protein complex. A comparison of the interaction with the homologous tetraspanin CD9, which also presents a dynamic open/closed equilibrium, underlined the marked selectivity of Hz-A/B for CD81 over CD9. …”
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5208
Macular Changes in a Mucopolysaccharidosis Type I Patient with Earlier Systemic Therapies
Published 2021-01-01“…The visual acuity was 5/10 in both eyes and she had bilateral grade 2 corneal haze. Spectral domain optical coherence tomography (SD-OCT) revealed thickening of the external limiting membrane (ELM) at the fovea. …”
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5209
Non-Linear Control of Interleaved Boost Converter Using Disturbance Observer-Based Approach
Published 2025-01-01“…An innovative Integral sliding-mode controller along with a disturbance observer for the two-phase IBC (2PIBC) is suggested to ensure such large-signal stability. The time-domain approach is employed to verify the averaged model of the system, which forms basis of designing the controlled system. …”
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5210
ET-1 Plasma Levels, Aqueous Flare, and Choroidal Thickness in Patients with Retinitis Pigmentosa
Published 2015-01-01“…Choroidal thickness and aqueous flare were measured, respectively, by using a spectral domain optical coherence tomography and a laser flare-cell meter, whereas plasma samples were obtained from each patient to evaluate ET-1 plasma levels. …”
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5211
An epigenetic memory at the CYP1A gene in cancer-resistant, pollution-adapted killifish
Published 2025-01-01“…We detected a bivalent domain in the CYP1A promoter enhancer comprising both activating and repressive histone post-translational modifications. …”
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5212
Correlation between Imaging Morphological Findings and Laboratory Biomarkers in Patients with Diabetic Macular Edema
Published 2021-01-01“…Participants in this cross-sectional study were 36 consecutive patients (36 eyes) with treatment-naïve DME, who underwent spectral domain-optical coherence tomography (SD-OCT), fundus photography, and fundus fluorescein angiography (FFA). …”
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5213
Pars Plana Vitrectomy Combined with Focal Endolaser Photocoagulation for Idiopathic Macular Telangiectasia
Published 2014-01-01“…The best-corrected visual acuity (BCVA) was determined, and fluorescein angiography (FA) and spectral domain optical coherence tomography (SD-OCT) were performed before and after surgery for up to 19 months. …”
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5214
Improving WRF-Chem PM2.5 predictions by combining data assimilation and deep-learning-based bias correction
Published 2025-01-01“…Besides having the best optimization effect over the whole domain, the combined method also performed well in different regions: during the forecasting period of 0–24 h, the RMSEs decreased from 32 % to 62 %, 39 % to 57 %, 28 % to 40 %, and 30 % to 49 % in the Beijing–Tianjin–Hebei, Yangtze River Delta, Central China, and Sichuan Basin urban agglomerations, respectively.…”
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5215
FBATCNet: A Temporal Convolutional Network With Frequency Band Attention for Decoding Motor Imagery EEG
Published 2025-01-01“…Subsequently, convolutional block further integrated frequency-domain features and extracted spatial features. Finally, a temporal convolution block was utilized to capture advanced temporal features. …”
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5216
Normative Values of Peripapillary Retinal Nerve Fiber Layer Thickness in a Middle Eastern Population
Published 2018-01-01“…Measurements had been recorded using Fourier-domain optical coherence tomography. Multivariable regression models were developed to generate predicted normative values with adjustments to candidate confounders. …”
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5217
Differences Between Amblyopic and Fellow Eyes in Optical Coherence Tomography: A Cohort from Jordanian Population
Published 2025-01-01“…Both eyes underwent spectral-domain OCT imaging, and clinical and demographic information was gathered. …”
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5218
Relationship between Neovascular Density in Swept Source-Optical Coherence Tomography Angiography and Signs of Activity in Exudative Age-Related Macular Degeneration
Published 2019-01-01“…Clinically active disease was evaluated by slit-lamp fundus examination and spectral domain-OCT B-scans. Morphological appearance in SS-OCTA was characterized based on 5 different criteria and subsequently divided into 3 groups: predominantly hyperdense, minimally hyperdense, and hypodense lesions. …”
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5219
The Impact of Child Dental Caries and the Associated Factors on Child and Family Quality of Life
Published 2023-01-01“…The predictors of suboptimal ECOHIS related to family domain were sex (girl): r (756) = 0.39 and P=0.047; mother education (under12): r (756) = −0.92 and P<0.001; mother job (employed) as univariate: r (756) = 0.71 and P=0.002); and dmft: r (756) = −0.58 and P=0.035. …”
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5220
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis
Published 2025-01-01“…Lipid droplets (LDs) are transient lipid storage organelles that can be readily tapped to resupply cells with energy or lipid building blocks, and therefore play a central role in cellular metabolism. Double FYVE Domain Containing Protein 1 (DFCP1/ZFYVE1) has emerged as a key regulator of LD metabolism, where the nucleotide-dependent accumulation of DFCP1 on LDs influences their size, number, and dynamics. …”
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