On the specifics of valuing effort: a developmental and a formalized perspective on preferences for cognitive and physical effort by Wolff, Wanja, Stähler, Johanna, Schüler, Julia, Bieleke, Maik

“…Critically, individual-difference research that investigates if this valuation of effort is domain-general or specific to cognitive or physical contexts is lacking. …”
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Cellular senescence-associated gene IFI16 promotes HMOX1-dependent evasion of ferroptosis and radioresistance in glioblastoma by Yuchuan Zhou, Liang Zeng, Linbo Cai, Wang Zheng, Xinglong Liu, Yuqi Xiao, Xiaoya Jin, Yang Bai, Mingyao Lai, Hainan Li, Hua Jiang, Songling Hu, Yan Pan, Jianghong Zhang, Chunlin Shao

“…By targeting the pyrin domain of IFI16, glyburide emerges as a potential therapeutic agent against GBM radioresistance. …”
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Noise Elimination for Wide Field Electromagnetic Data via Improved Dung Beetle Optimized Gated Recurrent Unit by Zhongyuan Liu, Xian Zhang, Diquan Li, Shupeng Liu, Ke Cao

“…Therefore, the IDBO-GRU is more adept at processing the time domain sequence, and the application results also validate that the proposed method can offer technical support for electromagnetic inversion interpretation.…”
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A 1.5D Spectral Kurtosis-Guided TQWT Method and Its Application in Bearing Fault Detection by Xiong Zhang, Ming Zhang, Shuting Wan, Rujiang Hao, Yuling He, Xiaolong Wang

“…In this paper, the signal is processed by the tunable Q-factor wavelet transform (TQWT), the midfrequency band of the signal is tightly divided by selecting different Q-values, and the 1.5D spectral kurtosis defined in frequency domain is used to select the optimal subband. Simulated analysis shows that this method can avoid low-frequency harmonic interference, nonperiodic transient impulse components, and strong noise components in the time domain. …”
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Automatic Multitarget Detection Method Based on Distributed Through-wall Radar by Xiao LIANG, Shengbo YE, Chenyang SONG, Yubing YUAN, Qunying ZHANG, Xiaojun LIU, Hejun JIANG, Hong LI

“…First, the echo signal is preprocessed in the time domain and then transformed into the time-frequency domain. …”
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Multi-modal denoised data-driven milling chatter detection using an optimized hybrid neural network architecture by Haining Gao, Haoyu Wang, Hongdan Shen, Shule Xing, Yong Yang, Yinlin Wang, Wenfu Liu, Lei Yu, Mazhar Ali, Imran Ali Khan

“…Sensitivity analysis of time–frequency domain features is conducted using Pearson correlation coefficient analysis. …”
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Experimental study on modal analysis and vibration response of tunnel structures under different damage conditions due to subway train loads by Rui Hou, Tao Li, Zhongyu Zhang, Lingfeng Li, Bo Liu, Dongwei Ren

“…Initially, the polynomial fitting modal identification method (Levy) and the model test preparation process are introduced. Then, using time-domain peak acceleration, frequency response function, frequency-domain modal frequency, and modal shape indicators, a detailed analysis of the tunnel’s dynamic response is conducted. …”
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A machine learning approach for vocal fold segmentation and disorder classification based on ensemble method by S. M. Nuruzzaman Nobel, S. M. Masfequier Rahman Swapno, Md. Rajibul Islam, Mejdl Safran, Sultan Alfarhood, M. F. Mridha

“…Abstract In the healthcare domain, the essential task is to understand and classify diseases affecting the vocal folds (VFs). …”
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Using Attention for Improving Defect Detection in Existing RC Bridges by Sergio Ruggieri, Angelo Cardellicchio, Andrea Nettis, Vito Reno, Giuseppina Uva

“…As such, this research proposes a new, simple, intuitive and efficient tool to support engineers and surveyors in assessing the health state of existing RC bridges. To this end, domain experts gathered and labelled a dataset of real images containing typical defects found in existing RC bridges. …”
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Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration by Paul Tamburini, Dennis Vestergaard Pedersen, Denise Devore, Josh Cone, Rekha Patel, Todd Hunter, Fang Sun, Gregers Rom Andersen, Jeffrey Hunter

“…Tarperprumig incorporates a C-terminal variable domain of a heavy chain only antibody (VHH) that binds properdin (FP) connected via a flexible linker to an N-terminal VHH that binds human serum albumin (HSA). …”
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Exploring female otolaryngologists’ experiences with gender bias and microaggressions: a cross sectional Canadian survey by Amanda C. Hu, Kelly Nguyen, Tanya K. Meyer

“…In the sexual objectification domain, trainees had higher frequency (p = 0.04), severity (p = 0.02) and total MESS (p = 0.02) scores than attendings. …”
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Simultaneous Measurements of PM2.5- and PM10-bound Benzo(a)pyrene in a Coastal Urban Atmosphere in Poland: Seasonality of Dry Deposition Fluxes and influence of Atmospheric Transpo... by Patrycja Siudek, Wiesława Ruczyńska

“…Additionally, the three-dimensional FLEXTRA transport model was used to identify the impact of different sources on air masses over the study domain. FLEXTRA results showed that the air masses transported from distant S to W regions greatly affected the chemical composition of PM2.5 and PM10 during autumn and winter.…”
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Frameshift variation in the HMG-CoA reductase gene and unresponsiveness to cholesterol-lowering drugs in type 2 diabetes mellitus patients by Esmat Khaleqsefat, Khder Hussein Rasul, Ramiar Kamal Kheder, Sonia Baban, Jamil Baban

“…Genetic analysis revealed a cytosine nucleotide insertion in the catalytic domain of the HMGCR gene in only two non-responsive participants to atorvastatin 40 mg therapy. …”
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CRISPR/Cas9-mediated genomic insertion of functional genes into Lactiplantibacillus plantarum WCFS1 by Kamilla Wiull, Lisa K. Haugen, Vincent G. H. Eijsink, Geir Mathiesen

“…Our system successfully knock-in four expression cassettes varying in length from ~800–1,300 bp with high efficiency and insert an expression cassette encoding a SARS-CoV-2 antigen receptor-binding domain (RBD) with an anchor mediating surface display, which has not been achieved previously using CRISPR/Cas9. …”
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RHOBTB2 Variant p.Arg511Gln Causes Developmental and Epileptic Encephalopathy Type 64 in an Infant: A Case Report and Hotspot Variant Analysis by Qian Liu, Feifei Li, Qin Ruan, Nana Wang, Zhengjun Fan

“…More than half of the variants are located at Arg483 and Arg511 within the BTB domain; however, the underlying mechanism of action of these hotspot variants remains unexplored. …”
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Cortical tracking of hierarchical rhythms orchestrates the multisensory processing of biological motion by Li Shen, Shuo Li, Yuhao Tian, Ying Wang, Yi Jiang

“…In addition, only this higher-order, domain-specific cortical tracking effect correlates with individuals’ autistic traits, highlighting its potential as a neural marker for autism spectrum disorder. …”
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Development and Evaluation of a Hydrometeorological Forecasting System Using the Coupled Ocean-Atmosphere-Wave-Sediment Transport (COAWST) Model by Jing Zou, Chesheng Zhan, Haiqing Song, Tong Hu, Zhijin Qiu, Bo Wang, Zhiqian Li

“…Resulting from that, a forecasted bias of lower surface pressure, higher air humidity, stronger south wind, and so forth was also detected over the domain but at low values.…”
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Amelioration of Coagulation Disorders and Inflammation by Hydrogen-Rich Solution Reduces Intestinal Ischemia/Reperfusion Injury in Rats through NF-κB/NLRP3 Pathway by Ling Yang, Yan Guo, Xin Fan, Ye Chen, Bo Yang, Ke-Xuan Liu, Jun Zhou

“…Additionally, HRS attenuated inflammatory responses and the elevated tissue factor (TF) and inhibited nuclear factor kappa beta (NF-κB) and nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation in peripheral blood mononuclear cells. …”
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Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity by Yujia Zhao, Dan Liu, Wenguang Yang, Wangxiao He, Jin Yan, Leiqing Yao

“…To overcome this issue, a meso chimeric peptide PEPPDL1 was designed to specifically bind the PD-1 binding domain of PD-L1 instead of the Hsc70/CMTM6 binding domain, while also binding to Hsc70 to facilitate the dragging of PD-L1 into Hsc70-mediated chaperone-mediated autophagy (CMA), thereby achieving lysosomal degradation. …”
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Through-wall Human Pose Reconstruction and Action Recognition Using Four-dimensional Imaging Radar by Rui ZHANG, Hanqin GONG, Ruiyuan SONG, Yadong LI, Zhi LU, Dongheng ZHANG, Yang HU, Yan CHEN

“…Additionally, to address the influence of walls on signal quality, this paper introduces a deep echo domain compensator that leverages the powerful fitting performance and parallel output characteristics of deep learning, thereby reducing the computational overhead of traditional wall compensation methods. …”
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