The Link between Overweight/Obesity and Noncommunicable Diseases in Ethiopia: Evidences from Nationwide WHO STEPS Survey 2015 by Bedilu Alamirie Ejigu, Fentanesh Nibret Tiruneh

“…Although the literature indicates that the burden of NCDs is increasing in Ethiopia, no research has been conducted to demonstrate a link between overweight/obesity and NCDs. …”
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Laminoplasty vs laminectomy in the surgical management of spinal intradural extramedullary tumors by Deepak Kumar Singh, Prevesh Kumar Sharma, Vipin Kumar Chand, Kaif Mohammad, Kuldeep Yadav, Neha Singh

“…Additionally, it alleviates the need for additional instrumentation, thereby avoiding an extra financial burden while enhancing the quality of life for the patient. …”
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Impact of Arterial Remodeling of Intermediate Coronary Lesions on Long-Term Clinical Outcomes in Patients with Stable Coronary Artery Disease: An Intravascular Ultrasound Study by Liang Geng, Peizhao Du, Yuan Yuan, Liming Gao, Yunkai Wang, Jiming Li, Qi Zhang

“…Negative remodeling lesions had the smallest minimum lumen area (4.16 ± 1.03 mm2 vs. 5.05 ± 1.39 mm2 vs. 4.85 ± 1.76 mm2; P<0.01), smallest plaque burden (63.45 ± 6.13% vs. 66.12 ± 6.82% vs. 71.17 ± 6.45%; P<0.01), and highest area stenosis rate (59.32% ± 10.15% vs. 54.61% ± 9.09% vs. 51.67% ± 12.96%; P<0.01). …”
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An Experimental Intervention Study Assessing the Impact of a Thin Silicone Gel Surface Overlay on Interface Pressure by Seth Kwadjo Angmorterh, Andrew England, Sonia Aboagye, Eric Kwasi Ofori, Peter Hogg

“…PUs creates a huge financial burden on healthcare authorities and patients, costing billions to treat and manage. …”
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Exploring Quality of Life in Adults Living With Late-onset Pompe Disease: A Combined Quantitative and Qualitative Analysis of Patient Perceptions from Australia, France, Italy, and... by Holly Lumgair, Lisa Bashorum, Alasdair MacCulloch, Elizabeth Minas, George Timmins, Drago Bratkovic, Richard Perry, Medi Stone, Vasileios Blazos, Elisabetta Conti, Raymond Saich

“…**Discussion:** These results demonstrate the humanistic burden of LOPD; through declining physical functioning SF-36 scores over increasing time and increased use of aids, and also through factors related to self-reported LOPD status (where declining status was associated with lower scores) and symptomology variances. …”
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Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies by Liu S, Li H, Xi S, Zhang Y, Sun T

“…These disorders, ranging from neurodegenerative diseases to psychiatric conditions, not only impact individuals but also place a substantial burden on healthcare systems and society. A major obstacle in treating these conditions is the blood-brain barrier (BBB), which restricts the passage of therapeutic agents to the brain. …”
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Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma by Hengchang Liu, Jialiang Liu, Xu Guan, Zhixun Zhao, Pu Cheng, Haipeng Chen, Zheng Jiang, Xishan Wang

“…TTN mutations also inhibit ANKRD1 expression via JUN disruption and enhance CD4/CD8 T‐cell infiltration, improving anti‐tumour immunity and outcomes. …”
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Retinopathy among Adult Diabetics and Its Predictors in Northwest Ethiopia by Mulualem Birhan Takele, Dube Jara Boneya, Hailemariam Abiy Alemu, Tesfa Birlew Tsegaye, Molla Yigzaw Birhanu, Simegn Alemu, Tsige Gebre Anto

“…Diabetic retinopathy is the leading cause of blindness among working-aged adults worldwide, including developing countries such as Ethiopia, and the burden of diabetes-related blindness is undeniably posing a massive challenge to the health care system. …”
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Pediatric Tuina for the treatment of functional dyspepsia: A systematic review and meta-analysis of randomized controlled trials by Na-Yeon Ha, Chang-Yul Keum, Jinsung Kim

“…Background: Functional dyspepsia (FD) is the most prevalent pediatric gastrointestinal disorder, imposing a significant burden on healthcare services and often persisting into adulthood. …”
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The association between serum fructosamine and random spot urine fructose levels with the severity of non-alcoholic fatty liver disease – an analytical cross-sectional study by H Kamuzinzi, M Kgomo, P Rheeder, N Dada, P Bester

“…Our local population is burdened with increased metabolic risk factors for NAFLD. …”
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Determinants of Adverse Perinatal Outcomes in Ibadan, Nigeria: The influence of maternal lifestyle. by Ikeola A Adeoye, Chioma O Unogu, Kofoworola Adediran, Babatunde M Gbadebo

“…Understanding these risk factors can help policymakers and healthcare professionals create cost-effective interventions to curtail the burden of APO in Nigeria.…”
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Benefits, limits, and risks of ChatGPT in medicine by Jonathan A. Tangsrivimol, Jonathan A. Tangsrivimol, Erfan Darzidehkalani, Hafeez Ul Hassan Virk, Zhen Wang, Zhen Wang, Jan Egger, Michelle Wang, Sean Hacking, Benjamin S. Glicksberg, Markus Strauss, Markus Strauss, Chayakrit Krittanawong, Chayakrit Krittanawong

“…It streamlines clinical workflows by supporting triage processes, generating discharge summaries, and alleviating administrative burdens, allowing healthcare professionals to focus more on patient care. …”
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Delayed Postoperative Ambulation Results in a Significant Increase in 90-Day Mortality in Surgically Treated Hip Fractures by Robert S. Wood DO, Maddie Vergun BS, Elizabeth Herrera MPH, Jacqueline Krumrey MD

“…Introduction Hip fractures in individuals aged 65 and older present a significant burden to patients, families, and health care systems. …”
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Central Obesity and Associated Factors among Adult Patients on Antiretroviral Therapy (ART) in Armed Force Comprehensive and Specialized Hospital, Addis Ababa, Ethiopia by Adnan Kemal, Mohammed Ahmed, Melese Sinaga Teshome, Kalkidan Hassen Abate

“…There are little data on the burden of abdominal obesity using the waist-to-hip ratio measurement in HIV-infected patients in resource-limited settings, including Ethiopia. …”
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Residence-based disparities of composite index of anthropometric failures in East African under five children; multivariate decomposition analysis by Aznamariam Ayres, Yawkal Tsega, Abel Endawkie, Shimels Derso Kebede, Eyob Tilahun Abeje, Ermias Bekele Enyew, Chala Daba, Lakew Asmare, Amare Muche, Fekade Demeke Bayou, Mastewal Arefaynie, Asnakew Molla Mekonen, Abiyu Abadi Tareke, Awoke Keleb, Kaleab Mesfin Abera, Natnael Kebede, Endalkachew Mesfin Gebeyehu

“…Results The current study revealed that the burden of composite index of anthropometric failure (CIAF) in under-5 children were 40.69%, 22.04%, 34.06%, 31.99%, and 33.27% in Ethiopia, Kenya, Rwanda, Uganda, and Tanzania respectively. …”
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Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution. by Nicolas Tessandier, Baptiste Elie, Vanina Boué, Christian Selinger, Massilva Rahmoun, Claire Bernat, Sophie Grasset, Soraya Groc, Anne-Sophie Bedin, Thomas Beneteau, Marine Bonneau, Christelle Graf, Nathalie Jacobs, Tsukushi Kamiya, Marion Kerioui, Julie Lajoie, Imène Melki, Jean-Luc Prétet, Bastien Reyné, Géraldine Schlecht-Louf, Mircea T Sofonea, Olivier Supplisson, Chris Wymant, Vincent Foulongne, Jérémie Guedj, Christophe Hirtz, Marie-Christine Picot, Jacques Reynes, Vincent Tribout, Édouard Tuaillon, Tim Waterboer, Michel Segondy, Ignacio G Bravo, Nathalie Boulle, Carmen Lía Murall, Samuel Alizon

“…Human papillomavirus (HPV) infections drive one in 20 new cancer cases, exerting a particularly high burden on women. Most anogenital HPV infections are cleared in less than two years, but the underlying mechanisms that favour persistence in around 10% of women remain largely unknown. …”
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Dataset on electricity usage measurement for lower-to-middle-income primary and secondary schools in Western Cape, South AfricaMendeley Data by Jason Avron Samuels, Terhemba Michael-Ahile, M. J. (Thinus) Booysen

“…Given this substantial financial burden, a comprehensive dataset to support the sustainability and financial viability of these schools is essential, ensuring that more resources can be directed toward their core educational missions. …”
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Respiratory pathogen spectrum and epidemiological trends in Hainan Province: a retrospective analysis from 2017 to 2023 by Lvying Wu, Jianan Zhang, Zhiming Wu, Hua Pei, You Zhang

“…Abstract Background Respiratory tract infections (RTIs) pose a significant global health burden, caused by various pathogens. The COVID-19 pandemic and non-pharmaceutical interventions (NPIs) have created unprecedented challenges for public health systems, inadvertently altering the dynamics of other respiratory pathogens. …”
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Assessment of Geriatric Problems and Risk Factors for Delirium in Surgical Medicine: Protocol for Multidisciplinary Prospective Clinical Study by Henriette Louise Möllmann, Eman Alhammadi, Soufian Boulghoudan, Julian Kuhlmann, Anica Mevissen, Philipp Olbrich, Louisa Rahm, Helmut Frohnhofen

“…A geriatric assessment with the content of basal and instrumental activities of daily living (basal activities of daily living [Katz index], instrumental activities of daily living [Lawton and Brody score], cognition [6-item screener and clock drawing test], mobility [de Morton Mobility Index and Sit-to-Stand test], sleep [Pittsburgh Sleep Quality Index and Insomnia Severity Index/STOP-BANG], drug therapy [polypharmacy and quality of medication, Fit For The Aged classification, and anticholinergic burden score], and pain assessment and delirium risk (Delirium Risk Assessment Tool) will be performed. …”
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Using Community Engagement to Create a Telecoaching Intervention to Improve Self-Management in Adolescents and Young Adults With Cystic Fibrosis: Qualitative Study by Christina L Duncan, Emily F Muther, Jennifer J Lindwall, Kristine Durkin, Elizabeth Ruvalcaba, Eliza Williamson, Corrine Ahrabi-Nejad, Evelyn Bord, Angela Green, Megan L Harrison, Deepika Polineni

“… BackgroundAdolescents and young adults (AYA) with cystic fibrosis (CF) are at risk for deviating from their daily treatment regimen due to significant time burden, complicated daily therapies, and life stressors. …”
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