Yorkshire Enhanced Stop Smoking (YESS) study: a protocol for a randomised controlled trial to evaluate the effect of adding a personalised smoking cessation intervention to a lung... by Richard D Neal, David Baldwin, Sarah Lewis, John Britton, Rachael L Murray, Qi Wu, Kate Brain, Samantha L Quaife, Matthew EJ Callister, Philip A J Crosbie, Harriet D Quinn-Scoggins, Grace M McCutchan, Alex Ashurst, Suzanne Rogerson, Rebecca Thorley

“…A process evaluation will explore under which circumstances and on which groups the intervention works best, test intervention fidelity and theory test the mechanisms of intervention impact.Ethics and dissemination This study has been approved by the East Midlands-Derby Research Ethics Committee (18/EM/0199) and the Health Research Authority/Health and Care Research Wales. …”
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Factors affecting the implementation of guideline-based prophylactic antiemetic therapy for chemotherapy-induced nausea and vomiting in Japan: a protocol for a hospital-based quali... by Yosuke Uchitomi, Junko Saito, Maiko Fujimori, Taichi Shimazu, Ayako Okuyama, Sadamoto Zenda, Ayumu Matsuoka, Akiko Yaguchi-Saito, Yuki Kaji, Miyuki Odawara, Aki Otsuki

“…Introduction Chemotherapy-induced nausea and vomiting (CINV) decrease patients’ quality of life and negatively impact treatment outcomes. Although standard prophylactic antiemetic therapy for acute CINV recommended by guidelines is effective, poor guideline implementation is a worldwide problem. …”
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Artificial Intelligence as an Object of Global Digital Governance by Diana Levchenko

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ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

“…Safety, radiological, other autoimmune and tertiary outcomes will also be assessed.Ethics and dissemination This trial has been approved by the UK National Research Ethics committee (South Central—Oxford A; REC 14/SC/1416). …”
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Study protocol for Adaptive ChemoTherapy for Ovarian cancer (ACTOv): a multicentre phase II randomised controlled trial to evaluate the efficacy of adaptive therapy (AT) with carbo... by Michelle Lockley, Kathy Robinson, Rowan Miller, Charlie Gourley, Nicholas Counsell, Iain Mcneish, Trevor Graham, Uma Anne Mukherjee, Helen Hockings, Apini Patel, Priya Narayanan, Katie Wilkinson, Harjot Dhanda, Alexander R A Anderson

“…Results of the trial will be disseminated through publication in peer-reviewed journals.Trial registration number NCT05080556.…”
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Harnessing new mHealth technologies to Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART trial): a protocol for a randomised controlled trial by Ben J Marais, Joel Negin, James Johnston, Virginia Wiseman, Greg J Fox, Thu Anh Nguyen, Binh Hoa Nguyen, Viet Nhung Nguyen, Justin Beardsley, Guy Barrington Marks, Kavindhran Velen, Tho Dang, Hoang Anh Nguyen, Dinh Hoa Vu, Thu Thuong Do, Cuong Pham Duc, Huu Lan Nguyen, Huu Thuong Pham, Warwick Britton

“…Cost-effectiveness will be presented as an incremental cost per patient successfully treated and an incremental cost per quality-adjusted life-year gained.Ethics Ethical approval for the study was granted by The University of Sydney Human Research Ethics Committee (2019/676).Dissemination Study findings will be disseminated to participants and published in peer-reviewed journals and conference proceedings.Trial registration number ACTRN12620000681954.…”
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plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute... by Thomas R Fanshawe, Philip J Turner, Gail N Hayward, Margaret Glogowska, Alastair D Hay, Michael Moore, Mark Lown, Christopher C Butler, Mandy Wootton, Mark H Wilcox, Jane Freeman, Nicola Kenealy, Valerie Tate, Owain Llion, Rebecca Lowe

“…Susceptibility testing will be performed using ‘gold-standard’ methods, not usually performed in diagnostic laboratories. …”
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Les insectes vivants dans l’espace anthropisé. Incarnations de la dichotomie nature/culture en architecture by Delphine Lewandowski

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Healthy lifestyle before and during pregnancy to prevent childhood obesity: study protocol for a parallel group randomised trial — the PRE-STORK trial by Tina Vilsbøll, Signe S Torekov, Julie Lyng Forman, Romain Barrès, Andreas Andersen, Filip K Knop, Signe Foghsgaard, Klaus Bønnelykke, Thomas Bergholt, Karoline Kragelund Nielsen, Christina Anne Vinter, Majken Lillholm Pico, Louise Groth Grunnet, Nina Kornerup, Julie Hagstrøm Danielsen, Ronni Eg Sahl, Mette Yun Johansen, Louise Kelstrup, Nida Ghauri, Emilie Grønlund, Lærke Lund

“…Children conceived during the trial will constitute a birth cohort, monitoring the effects on their health until the age of 18 years.Ethics and dissemination The trial has been approved by the Regional Committee on Health Research Ethics in the Capital Region of Denmark (identification number H-22011403) and will be conducted in agreement with the Declaration of Helsinki. …”
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Decolonization Projects by Cornelius Ewuoso

“…What type of inclusion does epistemic injustice require? Journal of Medical Ethics, jme-2023-109091. [14] 1998. …”
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Low-dose trimethoprim-sulfamethoxazole for the treatment of Pneumocystis jirovecii pneumonia (LOW-TMP): protocol for a phase III randomised, placebo-controlled, dose-comparison tri... by Andrea Benedetti, Cecilia T Costiniuk, Kosar Khwaja, Andrew Johnson, Barret Rush, Darrell Tan, Ranjani Somayaji, Salman Qureshi, Michaeline McGuinty, Nicole Ezer, Sara Belga, Emily G. McDonald, Zahra N. Sohani, Guillaume Butler-Laporte, Andrew Aw, Alex Carignan, Matthew P. Cheng, Bryan Coburn, Dan Gregson, Alexander Lawandi, Victor Leung, Sylvain Lother, Derek MacFadden, Leighanne Parkes, Valerie Roy, Ilan Schwartz, Miranda So, Emilie Trinh, Todd C. Lee

“…Results will be submitted for publication in a peer-reviewed journal.Trial registration number NCT04851015.…”
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Antireflux mucosal valvuloplasty versus proton pump inhibitors for the treatment of patients with gastro-oesophageal reflux disease in a tertiary healthcare centre in China: study... by Xiaofen Lv, Yunqing Zeng, Wenlong Ma, Jiaoyang Lu

“…However, there is currently no universally accepted standard for endoscopic surgery. Therefore, we introduced antireflux mucosal valvuloplasty (ARMV), an innovative endoscopic treatment for GERD. …”
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ANIMAL ISSUES IN THE POLITICAL AND LEGAL SPHERE IN RUSSIA AND ABROAD by BEZNOSOVA Yana Viktorovna, MINEEVA Tatiana Germanovna, ROMANOVSKAYA Vera Borisovna

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Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decorticati... by Liz Darlison, John Edwards, Apostolos Nakas, Nick A Maskell, Wendy Underwood, Chris Rogers, Matthew Callister, David Waller, Richard Milton, Victoria Ashford-Turner, Paul Taylor, Claire Matthews, Victoria Hughes, Kelvin Lau, Alan Kirk, Robert C Rintoul, Elizabeth A Stokes, Kate Ashton, Daisy Elliott, Rosie Harris, Marie Kirwan, Juliette Novasio, Sara Waplington, Eric Lim, Holly Mckeon, Charlotte Jacobs, Laura White, Mary O’Brien, Judith Moore, Louise Li, Nicola Mills, Sanjay Popat, Suzanne Miller, Nadia Yousaf, D A Fennell, Clinton Ali, Andrea Bille, Liz Fuller, Andreea Ionescu, Manjusha Keni, Pek Koh, Talal Mansy, Dakshinamoorthy Muthukumar, Tony Pope, Amy Roy, Riyaz Shah, Jonathan Shamash, Zacharias Tasigiannopoulos, Sarah Treece, Katherine Joyce, Barbara Warnes, Athanasia Gravani, Rachel Brophy, Nicola Farrar, Jane Elliott, Philip Noyes, Louise Nelson, Sara Tenconi, Laura Socci, Hilary Wood, Helena Hanratty, Helena Stanley, Robert Rintoul, Amy Gladwell, Jenny Castedo, Amanda Stone, Charlotte Ingle, Hayley Hewer, Eleanor Aynsley, Andrea Watson, Alison Hassall, Masuma Begum, Christopher Worth, Ellie Piggott, Elizabeth Nadin, Yvonne Summers, Raffaele Califano, Laura Cove-Smith, Matt Evison, Maria Blinston, Amal Ismail, Rachel Chant, Asmita Desai, Ian Morgan, Victoria Lake, Nichola Harris, Simon Hodge, Nadza Tokaca, Adam Januszewski, Avani Athauda, Anisha Ramessur, Emily Grist, Niamh Colman, Michael Flynn, Joan Joyce, Sarah Vaughan, Maria Piga, Derya Sahin, Agnieszka Yongue, Emma Turay, Jaishree Bhosle, Rajiv Kumar, Charlotte Milner-Watts, Jessica Brown, David Walder, Alexandros Georgiou, Xiaorong Wu, Naila Kaudeer, Kroopa Joshi, Michael Davidson, Shelize Khakoo, Bee Ayite, Kathryn Priest, James Dobbyn, Vasanthi Prathapan, Deborah McCrimmon, Natalie Ash, Alison Norton, Bianca Peet, Libby Hennessy, Rosemary Johnson

“…The QuinteT Recruitment Intervention is integrated into the trial to optimise recruitment.Ethics and dissemination Research ethics approval was granted by London – Camberwell St. …”
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Ultrasound-Guided Thoracic Paravertebral Injection of Platelet-Rich Plasma for the Treatment of Thoracic Herpes Zoster-Related Pain: A Study Protocol by Liu Wang, Xinyu Lei, Zhixuan Lan, Ruilin He, Zongbin Jiang

“…Results will be disseminated through scientific journals and conferences, contributing to global data on managing ZAP. …”
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Adaptation of an exercise intervention for pregnant women to community-based delivery: a study protocol by Aline Andres, Elisabet Børsheim, Taren Swindle, Audrey Martinez

“…We will randomise half to receive the community-adapted Expecting intervention (intervention, N=30) and half to receive standard of care (control, N=30). Feasibility and Acceptability of Intervention Measures are primary outcomes as key indicators of feasibility. …”
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PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label,... by David Taylor-Robinson, Steve Goodacre, Neil French, Richard Body, Kerenza Hood, Emma Thomas-Jones, Jane Daniels, Sarah Walker, Ingeborg Welters, Mike Bradburn, Paul Schmidt, Enitan Carrol, Lucy Brookes-Howell, Sarah Milosevic, Andrew Tabner, Philip Pallmann, Stephen Aston, Gavin Barlow, Emma Richards, Emmanuel Nsutebu, Philip Howard, Matthew Inada-Kim, Stacy Todd, Fiona McGill, Martin Llewelyn, Louis Wihelmus Niessen, Joanne Euden, Julie Carman, Stephanie Gilbert, Sam Clarkstone, Jacqui Hughes, Lena Meister, Angela Brain, Matthew Scarborough, Sian O'Shea, Claire James

“…Participants will be randomised in a ratio of 1:1 to standard clinical management based on NEWS2 scoring or standard clinical management based on NEWS2 scoring plus PCT-guided risk assessment. …”
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Parallel-group, randomised, controlled, non-inferiority trial of high-flow nasal cannula versus non-invasive ventilation for emergency patients with acute cardiogenic pulmonary oed... by Apichaya Monsomboon, Onlak Ruangsomboon, Nattakarn Praphruetkit

“…Evidence on its benefits compared with NIPPV, which is the standard of care for patients with acute cardiogenic pulmonary oedema (ACPE) with hypoxaemic respiratory distress, is limited. …”
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Estradiol and progesterone levels in early pregnancy after natural, estradiol + progesterone or gonadotrophin stimulated frozen embryo transfer cycle: a randomised controlled trial... by Nina Freiesleben Mørch, Mette Petri Lauritsen, Pernille Fog Svendsen

“…Furthermore, obstetric outcomes (live birth rates, birth weight, gestational age at birth, complications and malformations) and a possible association with serum estradiol and progesterone levels will be evaluated.Ethics and dissemination The three treatment regimens are all standard treatments and are comparable with regard to pregnancy rates. …”
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Research on stroke patients' perception of recurrence risk: A scoping review protocol. by Shanshan Zhu, Xueting Sun, Xin Guo, Meiqi Xu, Dingding Li, Shuaiyou Wang, Yage Shi, Chenjun Liu, Hongru Wang, Huimin Zhang

“…Furthermore, the findings will be reported.<h4>Ethics and dissemination</h4>Since this review involves collecting data from existing literature and does not involve human participants, ethical approval is not required. …”
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