Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: An update since 2020 by Yanqing Liu, Jie Chen, Xiang Li, Yu Fan, Cheng Peng, Xiaochun Ye, Yingshuang Wang, Xin Xie

“…Despite extensive research on RAS targeted therapies, developing effective RAS inhibitors remains a significant challenge. Natural products, endowed with unique chemical structures and diverse biological activities through long-term natural selection, have emerged as a vital resource for discovering novel RAS-targeted therapeutic drugs. …”
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Evaluation of spinal deformity and its progression in pyogenic spondylodiscitis: A retrospective MRI study of 59 cases by Andreas Kramer, Jonathan Neuhoff, Santhosh G. Thavarajasingam, Rebecca Sutherland, Hugh McCaughan, Benjamin Davies, Ehab Shiban, Florian Ringel, Andreas K. Demetriades

“…The distribution of deformity progression was: Type 1 in two cases (3%), Type 2 in seven cases (12%), Type 3 in 13 cases (22%), and Type 4 in 17 cases (29%). …”
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Effect of chronic kidney diseases-associated pruritus on patients’ sleep quality, well-being and its management by Inayat Ur Rehman, Tahir Mehmood Khan

“… Chronic kidney diseases-associated pruritus (CKD-aP) affects the patients’ mental and physical health, potentially resulting in fatigue, depression, and directly affecting quality of sleep. …”
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Seroprevalence of brucellosis in camels and humans in the Al-Qassim region of Saudi Arabia and its implications for public health by Abdulaziz M. Almuzaini, Abdullah S. M. Aljohani, Ahmed I. Alajaji, Ayman Elbehiry, Adil Abalkhail, Abdulrahman Almujaidel, Sahar N. Aljarallah, Hazem R. Sherif, Eman Marzouk, Abdelmaged A. Draz

“…Furthermore, 42.1%, 70.58%, and 47.05% of human sera that were positive for Brucella antibodies as determined by RBT were also positive according to I-ELISA and CFT, respectively. …”
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High-Speed Data-Driven Methodology for Real-Time Traffic Flow Predictions: Practical Applications of ITS by Hyun-ho Chang, Byoung-jo Yoon

“…Despite the achievements of academic research on data-driven k-nearest neighbour nonparametric regression (KNN-NPR), the low-speed computational capability of the KNN-NPR method, which can occur during searches involving enormous amounts of historical data, remains a major obstacle to improvements of real-system applications. …”
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Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

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Study on FSI Analysis Method of a Large Hydropower House and Its Vortex-Induced Vibration Regularities by Liaojun Zhang, Guojiang Yin, Shuo Wang, Chaonian Guan

“…A large-scale 3D fluid-hydraulic machinery-concrete structure coupled model of a hydropower house is established to study the vortex-induced vibration mechanism and coupled vibration law during transient unit operation. …”
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Influence Applied Potential on the Formation of Self-Organized ZnO Nanorod Film and Its Photoelectrochemical Response by Nur Azimah Abd Samad, Chin Wei Lai, Sharifah Bee Abd Hamid

“…Based on the results, ZnO nanorod films were successfully grown via electrochemical deposition in an optimum electrolyte set of 0.5 mM zinc chloride and 0.1 M potassium chloride at pH level of 5-6 and electrochemical deposition temperature of around 70°C. …”
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Reference Interval of Hemoglobin A1c and Influence of Hematological Parameters on Its Serum Concentration in Dogs by Stephan Neumann

“…In this study, we calculated a reference interval for HbA1c in dogs and investigated the correlation of HbA1c with hemoglobin and different hematological parameters. …”
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BIM Adoption and Its Impact on Planning and Scheduling Influencing Mega Plan Projects- (CPEC-) Quantitative Approach by Ahsan Nawaz, Xing Su, Ibrahim Muhammad Nasir

“…It has been analyzed that 2D CAD drawings are now getting primitive and 3D technology BIM is taking its place. …”
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A value-added cooking process to improve the quality of soybean: Protecting its isoflavones and antioxidant activity by Lei Chen, Hui Teng, Jianbo Xiao

“…It was found that β-glucosides isoflavones was significantly increased from 223.01 (raw) to 727.29 mg/g (frying at 160 °C for 2 min), but boiling showed only a slight increase to 258.14 mg/g. …”
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Genome-Wide Identification of Genes Probably Relevant to the Uniqueness of Tea Plant (Camellia sinensis) and Its Cultivars by Yan Wei, Wang Jing, Zhou Youxiang, Zhao Mingming, Gong Yan, Ding Hua, Peng Lijun, Hu Dingjin

“…In this report, based on expression data available from public databases, we performed a series of analyses to identify genes probably relevant to the uniqueness of C. sinensis and two of its cultivars (LJ43 and ZH2). …”
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A Proposal for a Zero-Trust-Based Multi-Level Security Model and Its Security Controls by Jun-Hyung Park, Sung-Chae Park, Heung-Youl Youm

“…The rapid advancement of technology and increasing data utilisation have underscored the need for new models to manage and secure big data effectively. However, the constraints of isolated network environments and the limitations of existing security frameworks hinder the adoption of cutting-edge technologies such as AI and cloud computing, as well as the safe utilisation of data. …”
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Exploring technical and vocational education and training and its relationship to employment in Nepal: a mixed methods study by Prakash Kumar Paudel, Mahesh Nath Parajuli, Prakash C Bhattarai

“…Second, we interviewed 15 individuals who were the respondents in the first survey. …”
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The role of milk urea nitrogen in nutritional assessment and its relationship with phenotype of dairy cows: A review by Xiaowei Zhao, Nan Zheng, Yangdong Zhang, Jiaqi Wang

“…It also describes the backgrounds of the gastrointestinal microbiota, intestine and kidney physiology in cows with different MUN concentrations, aiming to further enhance our understanding of MUN and provide a reference for optimal diets of cows.…”
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Transcriptomic analysis of Andrias davidianus meat and experimental validation for exploring its bioactive components as functional foods by Changge Guan, Zhenglin Tan, Shucheng Li, Yi Wang, Naoyuki Yamamoto, Chong Zhang, Songjun Wang, Junjie Chen, Xin-Hui Xing

“…By functional annotation and amino acid composition analysis, we have discovered various genes related to signal transduction, and 16 genes related to longevity. …”
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Global longitudinal strain and its dynamics after replacement of aortal valve in patients with severe aortic stenosis by N.V. Ponych, O.O. Nemchyna, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov

“…Кардіохірургія та інтервенційна кардіологія…”
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An Efficient Protocol for Deriving Liver Stem Cells from Neonatal Mice: Validating Its Differentiation Potential by Sugapriya Dhanasekaran, Devilakshmi Sithambaram, Kavitha Govarthanan, Bijesh Kumar Biswal, Rama S. Verma

“…Thus, the unlimited availability of cell type favors setting up the functional recovery of the damaged liver, ensuring ahead success towards treating liver diseases. …”
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Use of the Internet and its Impact on Productivity and Sales Growth in Female-Owned Firms: Evidence from India by Aparna Gosavi

“…It uses the World Bank’s Enterprise Surveys Program data set for the year 2014 to study the adopton of the Internet by more than 10,000 frms in the country. …”
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Quantum-inspired framework for big data analytics: evaluating the impact of movie trailers and its financial returns by Jaiteg Singh, Kamalpreet Singh Bhangu, Farman Ali, Ahmad Ali AlZubi, Babar Shah

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