Defining “Giant” Mediastinal Tumors: Proposal of a New Clinical–Radiological Classification and Case Report by Emanuel Palade, George Bucur Delaca, Ioana-Medeea Titu, Sergiu Adrian Ciulic, Gabriel Cismaru, Adrian Stef, Simona Manole

“…This study presents a new clinical–radiological classification (CRC) for mediastinal tumors and evaluates its applicability through a systematic review and a detailed case analysis of a giant thymolipoma. …”
Get full text

Estructura y dinámica de la población gallega entre 1950 y 2020. Entre la inercia y el pesimismo demográfico by Antía Pérez-Caramés

“…This article presents an analysis of the recent evolution of the Galician population, focusing both on aspects relating to its structure by sex and age, as well as its population dynamics. …”
Get full text

La (re)construction de l’autorité informationnelle dans les pratiques des journalistes québécois sur Twitter by Olivier Gadeau

“…Among the newer information and communications technologies, a significant portion of journalists (20%) have adopted Twitter as a work tool. Twitter touts itself to be one of the most effective ways for information providers to establish direct contacts with their audiences. …”
Get full text

Construction and Validation of a Major Depression Risk Predictive Model for Patients with Coronary Heart Disease: Insights from NHANES 2005–2018 by Li-xiang Zhang, Shan-bing Hou, Fang-fang Zhao, Ting-ting Wang, Ying Jiang, Xiao-juan Zhou, Jiao-yu Cao

“…Decision curve analysis (DCA) showed that when the threshold probability for major depression ranged from 0.04 to 0.54 in the development group and from 0.08 to 0.52 in the validation group, the nomogram provided the highest clinical net benefit compared to “Treat All” and “Treat None” strategies, confirming its strong clinical utility. …”
Get full text

Robot-assisted radical prostatectomy with da Vinci single-port system by Marek Kurowski, Karolina Kuczapska, Anna Gliwa, Monika Ryglewicz, Dariusz Fabian, Elżbieta Leszczyńska-Knaga, Natalia Jakubczyk, Weronika Rutkowska-Kawalec, Paweł Moczydłowski, Karolina Michalczuk

“…It is increasingly replacing open radical prostatectomies due to its higher treatment efficacy and fewer complications. …”
Get full text

Evolution Mechanism, Monitoring, and Early Warning Method of Water Inrush in Deep-Buried Long Tunnel by Wenfeng Tu, Liping Li, Shuai Cheng, Diyang Chen, Yongcai Yuan, Yanhao Chen

“…Through the remote real-time monitoring and early warning platform and its engineering application, the early warning of water inrush time trend and the early warning of water inrush rupture space position are realized.…”
Get full text

The Influence of Pores on Irradiation Property of Selected Nuclear Graphites by Zhengcao Li, Dongyue Chen, Xiaogang Fu, Wei Miao, Zhengjun Zhang

“…As structural material and moderator in high temperature gas-cooled reactor (HTGR), nuclear graphite endures large flux of irradiation in its service time. The microstructure of nuclear graphite is a topical issue studied to predict the irradiation property of graphite and improve manufacturing process. …”
Get full text

Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study by Carmen Tsang, Robert Wood, Tendai Mugwagwa, Kiran K Rai, Jingyan Yang, Theo Tritton, Jennifer L Nguyen, Kathleen Michelle Andersen, Maya Reimbaeva, Leah J McGrath, Poppy Payne, Bethany Emma Backhouse, Diana Mendes, Rebecca Butfield, Kevin Naicker, Mary Araghi

“…While few (6.0%) patients in critical care required mechanical ventilation, its use was higher in older adults (50–74 years: 8.3%; <50 years: 4.3%). …”
Get full text

Therapeutic Effect of Ginsenoside Rd on Experimental Autoimmune Encephalomyelitis Model Mice: Regulation of Inflammation and Treg/Th17 Cell Balance by Bo Jin, Chixiao Zhang, Yu Geng, Mei Liu

“…Inflammatory infiltrates and demyelination of the CNS are the major characteristics of MS and its related animal model-experimental autoimmune encephalomyelitis (EAE). …”
Get full text

Formation and development of the Acquis Communautaire in France, Germany and Switzerland: A comparative legal analysis by N. O. Rastorhuieva

“…On the basis of and through the disclosure of the concept of “acquis communautaire”, the diversity of its understanding within different approaches and the nature of this phenomenon, as well as the study of the formation of the acquis communautaire specifics, it is established that this process took place in the course of formation of the European Communities in the 1950s with the participation of France and Germany on the basis of a combination of liberal market and general social values, and its development took place during the elaboration of the foundations of the mechanism for adoption of a common European policy. …”
Get full text

NutriLive: An Integrated Nutritional Approach as a Sustainable Tool to Prevent Malnutrition in Older People and Promote Active and Healthy Ageing—The EIP-AHA Nutrition Action Group... by Maddalena Illario, Angela Serena Maione, Maria Rosaria Rusciano, Edwig Goossens, Amelia Rauter, Nidia Braz, Harriet Jager-Wittenaar, Carolina Di Somma, Catherine Crola, Maria Soprano, Laura Vuolo, Pietro Campiglia, Guido Iaccarino, Helen Griffiths, Tobias Hartman, Donatella Tramontano, Annamaria Colao, Regina Roller-Wirnsberger

“…“NutriLive” is an integrated nutritional approach, represented by a structured Screening-Assessment-Monitoring-Action-Pyramid-Model (SAM-AP). Its core concept is the stratification of the nutritional needs, considered by the working group as the key for targeted, effective, and sustainable interventions. …”
Get full text

Horrific Pasts and Mundane Presents: Living among the Jewish Ghosts of Warsaw and Lublin by Laura Chamberland, Hernan Tesler-Mabé

“…Focussing on the district of Muranow in Warsaw and the Majdanek site in Lublin, the authors argue that the juxtaposition of the horrific past and a more mundane present create a destabilizing disjunction – what Suzanne Knittel calls the “historical uncanny” – that unsettles and stands in the way of a Polish reconciliation with its Jewish past.       …”
Get full text

Forecasting Model of Gear Crack Fault based on FA-ASTFA and Minimum Convex Hull by Yang Yu, Zhu Zhengxiang, Cheng Junsheng

“…The adaptive and sparsest time-frequency analysis（ASTFA） can realize signal spare decomposition adaptively by using Gauss-Newton iteration,but Gauss-Newton iteration is very sensitive to initial value which is determined by experience. …”
Get full text

Strategy for developing human resources potential of Russian Railways by S. V. Lyukhanova, A. I. Solokhina

“…The article studies the human resources potential concept and its development on the example of Russian Railways, one of the largest companies in Russia. …”
Get full text

COSMC-Regulated O-Glycosylation: A Bioinformatics-Driven Biomarker Identification for Stratifying Glioblastoma Stem Cell Subtypes by Sara Sadat Aghamiri, Rada Amin

“…Moreover, Cosmc was associated with shorter progression-free intervals, suggesting its potential as an indicator of aggressive disease. …”
Get full text

Frictional Characteristics of Granite Fault under Imposed Dynamic Normal Disturbance Loads by Guojian Cui, Chuanqing Zhang, Qiming Xie

“…Additionally, we conducted a preliminary discussion on the slip mechanisms of the simulated fault under dynamic normal disturbance loading and its potential engineering implications.…”
Get full text

Therapeutic Activity of Lenalidomide in Mantle Cell Lymphoma and Indolent Non-Hodgkin’s Lymphomas by Marco Gunnellini, Lorenzo Falchi

Get full text

Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice by Weifeng Gu, Tingting Zheng, Wen Li, Xinkai Luo, Xiaowei Xu, Ying Wang, Chaoming Mao, Yongbin Ma, Liyang Dong

“…Abstract Background Asthma is a prevalent respiratory disease, and its management remains largely unsatisfactory. Mesenchymal stem cells (MSCs) have been demonstrated to be efficacious in reducing airway inflammation in experimental allergic diseases, representing a potential alternative treatment for asthma. …”
Get full text

Viscoelastic, Spectroscopic, and Microscopic Characterization of Novel Bio-Based Plasticized Poly(vinyl chloride) Compound by Mei Chan Sin, Irene Kit Ping Tan, Mohd Suffian Mohd Annuar, Seng Neon Gan

“…This study aimed to investigate the ability of an alternative greener material, medium-chain-length polyhydroxyalkanoates (mcl-PHA), a kind of biopolyester and its thermally degraded oligoesters, to act as a compatible bioplasticizer for PVC. …”
Get full text

Effect of Berberine on the Inflammatory Response of ANA-1 Cells Induced by Angiotensin Ⅱ Based on TLR4 Signaling Pathway by GAO Dexing, JIA Peizhi, PENG Jun, LIN Wei

“…Cell proliferation and toxicity test (CCK-8) was used to detect the effect of different concentrations of BBR on cell viability; the flow cytometry was used to detect the mean fluorescence intensity (MFI) of TLR4 on cell membrane ; ELISA method was used to detect the content of interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α); the real-time quantitative PCR was used to detect the mRNA level of IL-1β, IL-6, TNF-α; Western blot was used to detect the phosphorylation of p-ERK/ERK, p-p38/p38, p-JNK/JNK, p-p65/p65 and p-IRF3/IRF3 and the expression of TLR4, MyD88 and AP-1; the biochemical assay was used to detect the content of malondialdehyde (MDA) and the activity of superoxide dismutase (SOD).Results① CCK-8 assay results: compared with the control group, there was no significant difference in cell activity of the low, medium and high- dose BBR group, the difference was not statistically significant (<italic>P</italic>&gt;0.05). ② Flow cytometry results: compared with the fluorescent antibody group, MFI of the model group was significantly decreased; compared with the model group, MFI of the model group + the high dose BBR group was significantly increased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ③ ELISA results: compared with the control group, the content of IL-1β, IL-6, TNF- α of the model group was significantly increased; compared with the model group, the content of IL-1β, IL-6, TNF- α of the model group + the low, medium and high dose BBR group was significantly decreased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ④ Real-time quantitative PCR results: compared with the control group, the mRNA level of IL-1β, IL-6, TNF-α of the model group was significantly increased; compared with the model group, the mRNA level of IL-1β, IL-6, TNF- α of the model group + the low, medium and high-dose BBR group was significantly decreased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ⑤ Western blot results: compared with the control group, the phosphorylation expression of p65 and IRF-3 protein of the model group after intervention for 45 minutes was significantly increased, and the phosphorylation expression of p65, IRF-3 protein in the model group + the low, medium and high-dose BBR group was significantly decreased. …”
Get full text