Computer-assisted discovery of natural inhibitors for platelet-derived growth factor alpha as novel therapeutics for thyroid cancer by Hira Khalid, Farah Sattar, Iqra Ahmad, Valdir Ferreira de Paula Junior, Valdir Ferreira de Paula Junior, Umar Nishan, Umar Nishan, Riaz Ullah, Hanna Dib, Khaled W. Omari, Mohibullah Shah, Mohibullah Shah

“…Thus, novel anticancer drugs that inhibit its metastasis are urgently required. In this context, we proposed the PDGFRA inhibitors by an optimized structure-based drug design approach. …”
Get full text

Update on Clinical Inflammometry for the Management of Airway Diseases by Parameswaran Nair

“…Airway inflammation is a central feature of many airway diseases such as asthma, chronic bronchitis, bronchiectasis and chronic cough; therefore, it is only logical that it is measured to optimize its treatment. However, most treatment recommendations, including the use of anti-inflammatory therapies such as corticosteroids, are based on assessments of only airflow and symptoms. …”
Get full text

Spectroscopic and Thermooxidative Analysis of Organic Okra Oil and Seeds from Abelmoschus esculentus by Geórgia de Sousa Ferreira Soares, Vinicius de Morais Gomes, Anderson dos Reis Albuquerque, Manoel Barbosa Dantas, Raul Rosenhain, Antônio Gouveia de Souza, Darlene Camati Persunh, Carlos Alberto de Almeida Gadelha, Maria José de Carvalho Costa, Tatiane Santi Gadelha

“…Oil analysis through PDSC revealed an oxidation temperature of 175.2°C, which in combination with low amounts of peroxide, demonstrates its resistance to oxidation and favors its use for human consumption.…”
Get full text

Estimation of bearing capacity and serviceability of a floor slab after high-temperature exposure by A. N. Malahova

“…An analysis of the results of calculating a prestressed concrete ribbed floor slab before and after a fire showed a slight decrease in its bearing capacity after fire impact, an increase in the width of the crack opening and a significant increase in the deflection of the slab.…”
Get full text

Consequences of Surface Composition and Aggregation Conditions of Ag Nanoparticles on Surface-Enhanced Raman Scattering (SERS) of Pesticides by Marcelo José dos Santos Oliveira, Gilia Cristine Marques Ruiz, Rafael Jesus Gonçalves Rubira, Santiago Sanchez-Cortes, Carlos José Leopoldo Constantino, Leonardo Negri Furini

“…Additionally, to obtain the SERS signal of MBC with AgCT, besides the presence of chlorinated salts, other adjustments were necessary, such as changing both the pH of the medium (from pH 5.8 to pH 8, for which MBC is in its neutral form) and the laser lines (from 785 to 514.5 nm). …”
Get full text

Tomando buenas decisiones: La televisión y el aprendizaje de los niños pequeños, consejos para los padres by David C. Diehl, Stephanie C. Toelle

“…Toelle that addresses media and its effects on young children, from birth to age six. …”
Get full text

Modeling the significance of unified theory of acceptance and use of technology in predicting the intention and usage of eCNY by Yue Ma, Abdullah Al Mamun, Mohammad Masukujjaman, Roslan Ja’afar

“…Facilitating conditions and intentions toward the eCNY positively influenced its actual use. According to the findings of this study, age and sex did not moderate the effect of each hypothesis on the intention to use in the research model. …”
Get full text

Integration of Frequency Domain Wideband Antenna Nulling and Wavenumber Domain Image Formation for Multi-Channel SAR by M. Bucciarelli, D. Pastina, D. Cristallini, M. Sedehi, P. Lombardo

Get full text

MeHg Causes Ultrastructural Changes in Mitochondria and Autophagy in the Spinal Cord Cells of Chicken Embryo by Fabiana F. Ferreira, Evelise M. Nazari, Yara M. R. Müller

“…However, ultrastructural studies of its effects on the developing CNS are still scarce. …”
Get full text

Feature Selection in Cancer Classification: Utilizing Explainable Artificial Intelligence to Uncover Influential Genes in Machine Learning Models by Matheus Dalmolin, Karolayne S. Azevedo, Luísa C. de Souza, Caroline B. de Farias, Martina Lichtenfels, Marcelo A. C. Fernandes

“…This approach not only enhances model transparency but also maintains high classification performance, highlighting its potential in identifying biologically relevant features that may serve as biomarkers for cancer diagnostics and treatment planning.…”
Get full text

«Axiological Turn» in Russian Education: Position of Subjectivism by I. V. Yakovleva, S. I. Chernykh, T. S. Kosenko

“…Reflective theorizations about the state and prospects for the development of domestic education clearly recognize two trends in its future – continuity and individualization. In addition, the tendency of an “axiological turn” in the sense of education as a value and the value of education itself is clearly articulated. …”
Get full text

Pantothenate kinase 4 controls skeletal muscle substrate metabolism by Adriana Miranda-Cervantes, Andreas M. Fritzen, Steffen H. Raun, Ondřej Hodek, Lisbeth L. V. Møller, Kornelia Johann, Luisa Deisen, Paul Gregorevic, Anders Gudiksen, Anna Artati, Jerzy Adamski, Nicoline R. Andersen, Casper M. Sigvardsen, Christian S. Carl, Christian T. Voldstedlund, Rasmus Kjøbsted, Stefanie M. Hauck, Peter Schjerling, Thomas E. Jensen, Alberto Cebrian-Serrano, Markus Jähnert, Pascal Gottmann, Ingo Burtscher, Heiko Lickert, Henriette Pilegaard, Annette Schürmann, Matthias H. Tschöp, Thomas Moritz, Timo D. Müller, Lykke Sylow, Bente Kiens, Erik A. Richter, Maximilian Kleinert

“…Abstract Metabolic flexibility in skeletal muscle is essential for maintaining healthy glucose and lipid metabolism, and its dysfunction is closely linked to metabolic diseases. …”
Get full text

Testing a Web-Based Interactive Comic Tool to Decrease Obesity Risk Among Racial and Ethnic Minority Preadolescents: Randomized Controlled Trial by May May Leung, Katrina F Mateo, Marlo Dublin, Laura Harrison, Sandra Verdaguer, Katarzyna Wyka

“…ObjectiveThis study aimed to assess the feasibility and acceptability of Intervention INC (Interactive Nutrition Comics for Urban, Minority Preadolescents), a 6-chapter web-based interactive nutrition comic tool. Its preliminary effectiveness on diet-related psychosocial variables and behaviors was also explored. …”
Get full text

Acute Ascending Thrombosis of Abdominal and Suprarenal Aorta by Alessandro Robaldo, Stefano Pagliari, Patrizio Colotto

Get full text

Acknowledging the Intersectionality of Geoscientists With Disabilities to Enhance Diversity, Equity, Inclusion, and Accessibility by Ian O. Castro, Christopher L. Atchison

“…To improve the resources available for underrepresented scholars, the geoscience community must expand its exploration of identity beyond a singular construct, and instead focus on how identities intersect. …”
Get full text

A Liberal Peace Analysis of the UN Peacekeeping Operations in the DRC by Charles Nyuykonge

“…Its operation in the Democratic Republic of the Congo (DRC) is one of the largest operations in the history of UN peacekeeping operations in Africa. …”
Get full text

Active operations of Ashgabat branch of Russian-Asian Commercial Bank (1905–1917) by B. A. Alimdjanov

“…The topic of the history of banks’ activity in Central Asia has been little studied in national and world historiography, although its study allows revealing new aspects of the economic policy of the Russian Empire in the region. …”
Get full text

Chitosan’s Ability to Remove the Smear Layer—A Systematic Review of Ex Vivo Studies by Ana Ferreira-Reguera, Inês Ferreira, Irene Pina-Vaz, Benjamín Martín-Biedma, José Martín-Cruces

“…Ex vivo studies performed in non-endodontically treated extracted human permanent teeth with a fully formed apex, in which sodium hypochlorite was the main irrigant and chitosan was used as final irrigation to observe its capacity to remove the smear layer using a Scanning Electron Microscope (SEM), were included. …”
Get full text

On the use of the Theory of Critical Distances to estimate the dynamic strength of notched 6063-T5 aluminium alloy by T. Yin, A. Tyas, O. Plekhov, A. Terekhina, L. Susmel

“…In this paper the so-called Theory of Critical Distances is reformulated to make it suitable for estimating the strength of notched metals subjected to dynamic loading. The TCD takes as its starting point the assumption that engineering materials’ strength can accurately be predicted by directly post-processing the entire linear-elastic stress field acting on the material in the vicinity of the stress concentrator being assessed. …”
Get full text

On the approximate solution of the Cauchy problem for the Helmholtz equation on the plane by Davron Juraev, Nazira Mammadzada, Praveen Agarwal, Shilpi Jain

“…For this case, an explicit formula for the continuation of the solution and its derivative is established, as well as a regularization formula for the case when, under the specified conditions, instead of the initial Cauchy data, their continuous approximations with a given error in the uniform metric are given. …”
Get full text