Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study by Eshetie Melese Birru, Kevin T. Batty, Laurens Manning, Stephanie L. Enkel, Brioni R. Moore

“…Highlights: • Key barriers included (a) resistance from healthcare providers to administer benzathine penicillin G (BPG) due to their concerns about injection-related severe adverse events, and potential repercussions should an event occur, (b) poor community and healthcare provider awareness of the disease and its treatment, (c) lack of resources to manage adverse events, and (d) injection pain. • Key enablers included (a) perceived superior treatment benefits of BPG and (b) co-administration of lidocaine/analgesics to reduce injection pain. • Recommendations to address identified challenges include (a) improved training/education on RHD diagnosis, disease progression, and treatment, (b) improved access to supportive resources, (c) active adverse reaction monitoring and reporting, and (d) encouraging the provision/access of globally subsidized BPG suspension formulations in pre-filled syringes.…”
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The pathogenesis of COVID-19: Hypercoagulation and D-dimer in thrombotic complications by Leonid DUBEY, Halyna LYTVYN, Olha DOROSH, Nataliya DUBEY, Olena KOZLOVA, Michal PRUC, Nina KUBIKOWSKA, Lukasz SZARPAK, Kavita BATRA, Francesco CHIRICO, Gabriella NUCERA, Svitlana DOAN, Uljana SHEVTSIV

“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) caused a new coronavirus disease (COVID-19), which is highly contagious and its pathogenesis has not been fully elucidated. …”
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Topologically constrained DNA-mediated one-pot CRISPR assay for rapid detection of viral RNA with single nucleotide resolutionResearch in context by Yanan Li, Ru Xu, Fenglei Quan, Yonghua Wu, Yige Wu, Yongyuan Zhang, Yan Liang, Zhenzhong Zhang, Hua Gao, Ruijie Deng, Kaixiang Zhang, Jinghong Li

“…Via optimisation of CasTDR3pot to be one-pot assay, CasTDR1pot can detect Omicron and its subvariants, with only a few copies in clinical samples in less than 30 min without pre-amplification. …”
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Design and Characterization of Line-Waves Waveguides for Microwave Applications by Alessio Monti, Stefano Vellucci, Mirko Barbuto, Valentina Verri, Francesco Verni, Claudio Massagrande, Davide Ramaccia, Michela Longhi, Zahra Hamzavi-Zarghani, Luca Stefanini, Alessandro Toscano, Filiberto Bilotti

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Sodium Valproate Inhibits the Growth of Human Cholangiocarcinoma In Vitro and In Vivo by Bing Wang, Rui Yang, Yue Wu, Hongbo Li, Zouxiao Hu, Yongjun Chen, Shengquan Zou

“…In this study, sodium valproate, the clinically available form of VPA, was tested for its ability to inhibit the growth of cholangiocarcinoma cells, both in vitro and in vivo. …”
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Cookware as source of toxic metals: An overview by Okunola Alabi, Amos Tomiwa Afolabi

“…Cadmium in certain metal alloys and enamels, is another concern due to its toxicity, which affects various organs. Aluminum used in cookware, has raised health concerns because of its possible associations with neurodegenerative diseases. …”
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Hydrogen-Based Energy Systems for Sustainable Transportation by Matteo Genovese, Francesco Piraino, Petronilla Fragiacomo

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Characterization of heavy metal contamination in groundwater of typical mining area in Hunan Province by Wenjie Hao, Huan Liu, Shuli Hao, Kuanzhen Mao

“…The conclusions play a crucial role in implementing health and safety measures for the mining area and its surrounding residents. The statistical study results show that Mn, Se, As, and Sb are closely related to human mining activities and are polluted to varying degrees; the principal component analysis model indicates that the upstream monitoring points 26#, 22#, and 25# in the mining area groundwater are less polluted. …”
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Closing the Gap: Territorial Cohesion through Polycentric Development by Evert Meijers, Bas Waterhout, Wil Zonneveld

“…Its content remains however rather unclear. This paper contributes to the discussion on the meaning of polycentricity by looking at national polycentric development policies. …”
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Pastoral care and counselling in current times: Relevance and context of care by Glenda A. Dames, Gordon E. Dames

“…Contribution: This article provides a critical overview of pastoral care in its current form and context, examining its relevance to the existential needs of the postmodern social milieu and its role in the church today. …”
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The Health Impact of Cocoa from Cultivation to the Formation of Biogenic Amines: An Updated Review by Antonello Paparella, Maria Schirone, Clemencia Chaves López

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Differential fault analysis on the SMS4 cipher by inducing faults to the key schedule by LI Wei, GU Da-wu

“…On the basis of the byte-oriented fault model and the differential analysis,a differential fault analysis on the SMS4 cipher by inducing faults in its key schedule was proposed.Mathematical analysis and simulating experiment show that the attack could recover its 128-bit secret key by introducing only eight faulty ciphertexts.Simultaneously,a method of distinguishing effective faults was presented to increase the efficiency of fault injection and decrease the num-ber of faulty ciphertexts.Thus,experiment results are beneficial to the analysis of other iterated block ciphers.…”
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Keeping Food Safe: Special Tips for Potluck Parties by Claudia Peñuela, Amarat Simonne

“…To decrease your risk of foodborne illness, itis very important to follow the “two-hour rule” and refrigerate all prepared foods within two hours of purchasing or cooking. …”
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Left paraduodenal hernia: An overlooked cause of acute abdomen - A case report by Bhushan Shah, Jayant Bajaj, Adithya Reddy Vijendra, Devendra S. Yadav

“…Although rare, a high index of suspicion of PDH is required to prevent its fatal complications such as bowel incarceration, volvulus, or strangulation. …”
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Evaluation of e-Lung automated quantitative computed tomography biomarkers in idiopathic pulmonary fibrosis by Peter M. George, Christian Rennison-Jones, Giacomo Benvenuti, Aliki Sifostratoudaki, Finja A. Ottink, Wassim Bou-Zeid, Roberta E. Ledda, Roqia F. Abul Kadir, Bushra Johari, Claire Fernandez, George W.J. Harston, Olivier Joly, Stephen Gerry, Anand Devaraj

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Methodology to minimize the dynamic response of tall buildings under wind load controlled through semi-active magneto-rheological dampers by Alex Koch de Almeida, Francisco da Silva Brand�o, Let�cia Fleck Fadel Miguel

“…In the second configuration, called Uncontrolled Optimized (C2), the fundamental frequency of the building is optimized via PSO algorithm as a function of its mass. Then, in the third configuration, Controlled Optimized (C3), a set of MR dampers with behavior formulated via the modified Bouc-Wen rheological model and controlled through the Linear Quadratic Regulator associated with the Clipped Optimal control strategy (LQR-CO) is applied to the structure. …”
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Bibliothèques publiques et virage citoyen : enjeux institutionnels et communicationnels by François R. Derbas Thibodeau, Christian Poirier

“…This article discusses communicational and institutional questions raised by the ongoing transformation of the public library and its relationships to users and the broad public. …”
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Monitoring for the genetic structure of Mezen breed of horses in terms of DNA microsatellites by N. V. Vdovina, I. B. Yuryeva

“…Due to a small population of Mezen horses, the challenge of preserving its intra-breed diversity is very urgent. To determine the degree of genetic variability in the Mezen population, the alleles-fond was monitored. …”
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Distribution and Numbers of Three Globally Threatened Waterbird Species Wintering in Morocco: The Common Pochard, Marbled Teal, and White-Headed Duck by Asmaâ Ouassou, Mohamed Dakki, Mohammed-Aziz El Agbani, Abdeljebbar Qninba, R’himou El Hamoumi

“…Marmaronetta angustirostris has a stable trend over the years even though its population can know high annual fluctuations; it winters in more or less 50 wetlands, among which 18 host more than 1% of its regional population and 16 verify the criteria for national importance. …”
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Évolution des registres de l’action, de la ruse à la mobilisation de la notion « droit » par les habitants des bidonvilles au Maroc by Habiba Essahel

“…The former is undergoing an in-situ relocating operation resulting in a minor transfer of some of its inhabitants, while the latter’s population is being relocated in distant outskirts of the city. …”
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