Transforming the landscape of cancer treatment with seven promising novel therapies: evolution and future perspectives by Huilei Miao, Yuan Fang, Chongxian Pan, Hanshuo Yang, Zhipeng Wang, Ye Qi, Yan Wu, Ying Zhang, Fangpeng Liu, Huiyao Huang, Yu Tang, Dawei Wu, Ning Li

“…Cell therapies beyond autologous chimeric antigen receptor-T (CAR-T), such as in vivo CAR-T, are advancing with improved manufacturing processes. Gene therapies, such as miRNA-targeting approaches and plant immune protein RDR1, offer new strategies for restoring gene expression. …”
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A temperature responsive hydrogel encapsulated with adipose‐derived stem cells and melanin promotes repair and regeneration of endometrial injury by Ruigao Song, Chicheng Ma, Hongxia Li, Yu Cheng, Xianmei Cui, Zanhong Wang, Lijuan Huang, Chunying Song, Yukai Jing, Bing Cao, Lili Wang, Qing Tian, Xi Wang, Ruiping Zhang, Hanwang Zhang

“…Recent advancements in stem cell research have opened new possibilities for the treatment and repair of endometrial issues. In the present study, we constructed a degradable hydrogel by loading adipose‐derived stem cells (ADSCs) and melanin nanoparticles (MNP). …”
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Influencing factors of bentonite for the directional electric repair of landfill HDPE membrane leakage in calcium ion solution by Guangyuan Yao, Yuqiang Liu, Ya Xu, Jingcai Liu, Can Qian, Yanmei Yang, Zhu Liang, Minsong Lin

“…Electric repair technology is expected to become a hot spot in the leakage repair of HDPE films, because it can solve the issues of complex operation, high costs, and security risks during the operation and closure of landfills. …”
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MODELLING THE IMPACT OF INTELLECTUALIZATION ON ECONOMIC GROWTH IN UKRAINE by Iryna Kalenyuk, Larysa Antoniuk, Oleg Kuklin, Liudmyla Tsymbal, Olena Tsyrkun

“…In the economies of countries with a rustic system, these processes are quite insignificant, which is due to limited development opportunities. …”
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Preventing Microorganism Contamination in Starting Active Materials for Synthesis from Global Regulatory Agencies: Overview for Public Health Implications by Francesco Gravante, Francesco Sacchini, Stefano Mancin, Diego Lopane, Mauro Parozzi, Gaetano Ferrara, Marco Sguanci, Sara Morales Palomares, Federico Biondini, Francesca Marfella, Giovanni Cangelosi, Gabriele Caggianelli, Fabio Petrelli

“…The introduction of SAMS marks the point where Good Manufacturing Practices (GMP) begin to apply, which are essential for ensuring sterility and preventing microbial contamination during the synthesis process. However, defining the exact point in the process that qualifies as the SAMS is subject to uncertainties, as earlier stages are not always governed by stringent GMP standards. …”
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Organisation of physical education in universities for students with disabilities: Modular approach by L. V. Zakharova, O. N. Moskovchenko, U. Solimene, N. V. Tretyakova, N. V. Bannikova, N. V. Lyulina, O. A. Kattsin

“…Also, the authors used the methods of mathematical statistics to process the study results. The received data were processed with Microsoft Office Excel. …”
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Mitigation of flow instabilities in multiport minichannel thermosyphon through a modified loop design with separate vapor-liquid paths by Jaya Antony Perinba Selvin Raj, Lazarus Godson Asirvatham, Appadurai Anitha Angeline, Bairi Levi Rakshith, Jefferson Raja Bose, Stephen Manova, Vivek Vengatoor Mana, Mostafa Safdari Shadloo, Somchai Wongwises

“…Multiport minichannel thermosyphons with hydraulic diameters below 1.2 mm often encounter severe flow instabilities and oscillations in vapor and condensate movement, which hinder effective phase change processes. These instabilities can cause partial and localized dry-out, resulting in higher operating temperatures and reduced thermal performance. …”
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Development and implementation of digital solutions in healthcare: insights from the Australian tertiary hospital landscape by Rudolf J. Schnetler, Venkat N. Vangaveti, Venkat N. Vangaveti, Benjamin J. Crowley, Joshua K. Keogh, Trudie Harris, Dale Parker, Jane Watson, Teresa Edwards, Peter Westwood, Hudson Birden, Marina Daly, Kieran Keyes, Erik Biros, Erik Biros, Andrew J. Mallett, Andrew J. Mallett, Andrew J. Mallett, Andrew J. Mallett

“…The Audit, Quality, and Innovation Review panel simplifies the approval process using digital workflows for quality assurance and audit projects, and the Research Data Laboratory provides secure access to de-identified patient data and supports data analysis.DiscussionUnlike some countries, such as the US and UK, where financial incentives or established networks drive research integration, the Townsville Hospital and Health Service focuses on empowering clinicians to address local healthcare issues through research directly. …”
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Toward equity in cultivating a “garden of mentors:” An exploration of networking experiences in an implementation research training program by Loni J. Parrish, Amanda Gilbert, Kate Hoppe, Gloria D. Coronado, Karen M. Emmons, Amy A. Eyler, Debra Haire-Joshu, Rebekah R. Jacob, Alison B. Hamilton, Shelly J. Kannuthurai, Ross C. Brownson

“…Qualitative data showed a lack of connection, reluctance to network, and systematic issues including institutional biases as possible drivers of group differences. …”
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H2O-balance-regulated cation–anion competitive coordination for selective elements extraction from spent lithium-ion batteries by Mingqiang Cheng, Yixin Hua, Qibo Zhang, Qihao Li, Hongda Li, Ding Wang, Xianshu Wang, Yun Zhao, Juanjian Ru, Baohua Li

“…However, the current recovery method from spent LIBs is hindered by low efficiency, high energy consumption, and severe environmental issues, which curtail the sustainability of recycling industry. …”
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Prevalence and intensity study of dental caries in children with bronchial asthma by O. V. Voznyi, Т. Ye. Shumna, Ye. S. Lepetchenko

“…The study of the carious process prevalence included 158 children with bronchial asthma (50 girls, 108 boys), aged between 3 and 17 years. …”
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Dynamic venting simulation of valve chambers at both ends of supercritical CO2 pipelines with topographic relief by Bing YAN, Bohui SHI, Junwen CHEN, Xiaoyong TANG, Linfeng ZAN, Yanjing WANG, Yupei LI, Jing GONG

“…A dynamic simulation analysis of pipeline venting was conducted, revealing the physical nature of the low-temperature phenomenon in the main pipeline during venting. Key issues in the venting process of the supercritical CO2 pipeline with topographic relief were discussed, focusing on the effects of topographic relief on phase transition, low-temperature risks, and dry ice formation. …”
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Unravelling Secondary Brain Injury: Insights from a Human-Sized Porcine Model of Acute Subdural Haematoma by Thomas Kapapa, Vanida Wernheimer, Andrea Hoffmann, Tamara Merz, Fabia Zink, Eva-Maria Wolfschmitt, Oscar McCook, Josef Vogt, Martin Wepler, David Alexander Christian Messerer, Claire Hartmann, Angelika Scheuerle, René Mathieu, Simon Mayer, Michael Gröger, Nicole Denoix, Enrico Clazia, Peter Radermacher, Stefan Röhrer, Thomas Datzmann

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Scoping Review of Economic Analyses of Rare Kidney Diseases by Blake Angell, Siyuan Wang, Thomas Gadsden, Monica Moorthy, Charu Malik, Jonathan Barratt, Olivier Devuyst, Ifeoma I. Ulasi, Daniel P. Gale, Agnivo Sengupta, Anna Palagyi, Vivekanand Jha, Stephen Jan

“…There may be significant scope for innovation in building an investment case for RKD treatments, as well as in decision-making processes to inform investment decisions.…”
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Effect of solution-aging treatment on the microstructure and hydrogen embrittlement susceptibility in laser-powder bed fusion maraging steel by Nan Zhou, Youpeng Xie, Yuyan Xiao, Xiaoyu Wang, Zhixian Peng, Zhaoyang Cheng, Jing Liu, Feng Huang, Shiqi Zhang

“…Hydrogen embrittlement (HE) is one of the key issues limiting the application of laser-powder bed fusion (LPBF) 18Ni-300 maraging steels. …”
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Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources by Magdalena Mititelu, Dumitru Lupuliasa, Sorinel Marius Neacșu, Gabriel Olteanu, Ștefan Sebastian Busnatu, Andreea Mihai, Violeta Popovici, Nicoleta Măru, Steluța Constanța Boroghină, Sebastian Mihai, Corina-Bianca Ioniță-Mîndrican, Alexandru Scafa-Udriște

“…Furthermore, it highlights the necessity for dietary shifts towards increased PUFA intake to mitigate the global burden of diet-related health issues. The co-occurrence of PUFAs and polyphenols in plant-based foods highlights the sophistication of nature’s design. …”
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The relationship between fear of negative evaluation, physical activity, eating behavior and psychological distress among nursing students by Xiao Zheng, Mengjie Zhang, Lingli Yang, Xinyi Zhang, Shujuan Xiao, Xinru Li, Benli Xue, Yanming Liao, Feng Tian, Chichen Zhang

“…The relationship models among the aforementioned variables were established using Process 3.5.Results A total of 290 males and 602 females were included in this study. …”
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Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex by Katie Morris, Edita Bulovaite, Takeshi Kaizuka, Sebastian Schnorrenberg, Candace T Adams, Noboru Komiyama, Lorena Mendive-Tapia, Seth GN Grant, Mathew H Horrocks

“…However, it is unknown whether the subunits of protein complexes that mediate memory are sequentially replaced in the brain and if this process is linked to protein lifetime. We address these issues by focusing on supercomplexes assembled by the abundant postsynaptic scaffolding protein PSD95, which plays a crucial role in memory. …”
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Structural Explanation of Urban Tourism Development Challenges in Chaharmahal and Bakhtiari Cities by Arash Fazeli, Nafiseh Marsousi, Mohsen Saghaei

“…Moreover, enhancing infrastructure and effectively managing tourist attractions will significantly contribute to this development process, resulting in a stable and efficient growth trajectory for tourism in the region.…”
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