Clinical Significance of the Serum 3′tRF-AlaAGC, Neutrophil to High-Density Lipoprotein Ratio, and Lymphocyte-to-Monocyte Ratio in Breast Cancer with Lymph Node Metastasi... by Mo D, Zhu Y, Mao X, Li C, Yang Y, Zheng J, Yan F

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Endovascular Treatment in Stroke Patients of Working Age: A Multicenter Observational Study of Real-World Outcomes by Zhou Y, Mofatteh M, Zheng Z, Liu F, Zhou S, Ma J, Yan Z, Lai Y, Li W, Chen W, Abdalkader M, Regenhardt RW, Liu X

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Exploring unsupervised feature extraction algorithms: tackling high dimensionality in small datasets by Hongqi Niu, Gabrielle B. McCallum, Anne B. Chang, Khalid Khan, Sami Azam

“…Abstract Small datasets are common in many fields due to factors such as limited data collection opportunities or privacy concerns. …”
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Automated interpretation of deep learning-based water quality assessment system for enhanced environmental management decisions by Javed Mallick, Saeed Alqadhi, Majed Alsubih, Mohamed Fatahalla Mohamed Ahmed, Hazem Ghassan Abdo

“…Abstract Water quality assessment is a critical issue in the Aseer region of Saudi Arabia, where environmental and anthropogenic factors pose a major challenge to both drinking water and irrigation systems. …”
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Phytoplankton group classification by integrating trait information and observed environmental thresholds by Hoang Vuong Dang, Kermode Stephanie, Peisheng Huang, Cayelan C. Carey, Matthew R. Hipsey

“…However, this approach aggregates the substantial functional and trait diversity that occurs within these groups, creating challenges for model parameterization and assessment. To address this issue, we developed a data-driven approach to define phytoplankton functional groups considering species trait information and occurrence data. …”
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Periodontal diseases in Down syndrome during childhood: a scoping review by Valentin Vergier, Anne-Margaux Collignon, Marjolaine Gosset, Anne-Laure Bonnet

“…However, the evidence is inconclusive regarding the presence of bone loss, with studies divided on this issue. Local risk and etiopathogenetic factors do not seem to play a significant role in increased inflammation. …”
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Microbiome, resistome, and potential transfer of antibiotic resistance genes in Chinese wet market under One Health sectors by Juan Yang, Le Wang, Qian Liang, Yang Wang, Xiaorong Yang, Xianping Wu, Xiaofang Pei

“…However, the understanding of ARGs in this kind of market, including their shared profiles, influencing factors, and potential horizontal transfer subtypes and directions, remains limited. …”
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IMPROVING KNOWLEDGE ON CHILD MARRIAGE THROUGH SYNCHRONOUS LEARNING IN TANJUNGAN VILLAGE, MOJOKERTO, INDONESIA by Zahras Azimuth Doman, Annette d'Arqom, Mhd Zamal Nasution

“…Child marriage remains a prevalent issue in many regions, including Indonesia. This practice is associated with significant adverse outcomes, such as interrupted education, elevated maternal morbidity and mortality rates, and prolonged the cycle of poverty. …”
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CausalCervixNet: convolutional neural networks with causal insight (CICNN) in cervical cancer cell classification—leveraging deep learning models for enhanced diagnostic accuracy by Zahra Taghados, Zohreh Azimifar, Malihezaman Monsefi, Mojgan Akbarzadeh Jahromi

“…Abstract Cervical cancer is a significant global health issue affecting women worldwide, necessitating prompt detection and effective management. …”
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Cardiometabolic self-care and their determinants among older adults in India: evidence from the Longitudinal Ageing Study of India by Shubhanjali Roy, Arka Ghosh, Saurav Basu

“…Background: Cardiometabolic syndrome (CMS) is a major public health issue in India, driven by urbanization, unhealthy dietary shifts, and sedentary lifestyles. …”
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Mitigating drought stress in fenugreek through synergistic effects of alanine and potassium-enriched biochar by Wanzheng Ma, Xinyu Fang, Mengru Qiu, Misbah Hareem, Zeki Erden, Çağdaş Can Toprak, Abdullah A. Alarfaj

“…To overcome this critical issue, researchers suggest employing environmentally friendly approaches. …”
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Illuminating the Arctic: Unveiling seabird responses to artificial light during polar darkness through citizen science and remote sensing by Kaja Balazy, Dariusz Jakubas, Andrzej Kotarba, Katarzyna Wojczulanis‐Jakubas

“…The findings underscore the potential importance of this issue for seabird conservation in polar regions.…”
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Examining associations between oral cancer mortality and economic development of 13 European countries: an ecological and correlational study by Klára Boruzs, Eszter Barbara Bán, Viktor Dombrádi, Gábor Bányai, Gergő József Szőllősi, Klára Bíró

“…Abstract Background Cancer is a significant public health issue all over the world. The diagnosis, treatment and follow-up of cancer patients are a huge health, economic and social burden for societies. …”
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Wear Characteristics and Optimization Measures of Disc Cutters During Large-Diameter Slurry Tunnel Boring Machine Advancing in Soil-Rock Composite Strata: A Case Study by Yingran Fang, Xinggao Li, Yinggui Cao, Hongzhi Liu, Yidong Guo

“…However, cutter wear has become a critical issue that severely limits the tunnelling efficiency. …”
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Integrated Wavelet-Grey-Neural Network Model for Heritage Structure Settlement Prediction by Yonghong He, Pengwei Jin, Xin Wang, Shaoluo Shen, Jun Ma

“…To address the issue of insufficient prediction accuracy in traditional GM(1,1) models caused by significant nonlinear fluctuations in time-series data for ancient building structural health monitoring, this study proposes a wavelet decomposition-based GM(1,1)-BP neural network coupled prediction model. …”
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Optimization of self-sufficient hybrid renewable energy source fed BWRO desalting plant through fuzzy AHP and VIKOR MCDM techniques by D. Suriya kumari, P.S. Manoharan, K. Chidambarathanu, J. Vishnupriyan

“…The Fuzzy Analytic Hierarchy Process (Fuzzy AHP) and Vlkriterijumsko KOmpromisno Rangiranje (VIKOR) methods are utilized for a thorough exploration of the significance in selecting the optimal configuration and size for establishing a BWRO plant. The key factors for the BWRO plant encompass the energy usage of the water pump, solar energy generation, cost per unit of consumable water, NPC, pH level of the water, and the community's familiarity with the area. …”
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Short-term scheduling optimization of battery electric buses in the context of sustainable energy resources under uncertainty by Muhammad Ahmad Iqbal, Ismail I. Almaraj

“…The primary goal is to allocate BEB to the best CSs while focusing on increasing overall profit by serving the grid and passenger needs effectively. To solve this issue, several factors are considered, including transit hours, sustainable energy resources, state-of-charge (SOC), vehicle-to-grid (V2G) and grid-to-vehicle (G2V) service trading, bus, CS capacity, data-sharing, and route dynamics. …”
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Smartphone addiction and its association with accident risk in Iranian adults by Saber Azami-Aghdash, Fatemeh Abbasi Amandi, Hossein Mashhadi Abdolahi, Deniz Naghibi, Ramin Rezapour

“…Abstract In recent years, the widespread use of smartphones has led to concerns about smartphone addiction, which is now recognized as a major social and public health issue. This addiction has resulted in numerous negative consequences, the most significant of which is an increase in different types of accidents. …”
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Association between blood lead levels and constipation in adults: insights from NHANES data (2005–2010) by Yue-Juan Li, Hui Dong, Wen-Xing Chen, Deng-Chao Wang, Miao Yu

“…Abstract Background Constipation is a common health issue affecting quality of life. While environmental factors like lead exposure may influence gastrointestinal function, the link between blood lead levels and constipation is underexplored. …”
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Vitamin D management update: evidence-based guidelines for vitamin D optimization by the Egyptian Academy for bone and muscle health by Yasser El Miedany, Mathias Toth, Maha Mohamed El Gaafary, Safaa A. Mahran, Waleed Hassan, Mohammed Hassan Abu-Zaid, Walaa Elwakil, Walaa Basyoni Selim, Eman Ahmed Sultan, Ghada Saber Ibraheem, Salwa Galal Moussa

“…The Egyptian Academy for bone and muscle health is issuing an updated guidelines influenced by a substantial body of research conducted in recent years. …”
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