European Union: From social integration to social state by Brkić Luka

“…They are rather the expression of a voluntary and deliberate agreement, of a covenant. …”
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Development and characterization of a novel injectable thyroid extracellular matrix hydrogel for enhanced thyroid tissue engineering applications by Liang Zhang, Liang Zhang, Houlong Long, Houlong Long, Peng Zhang, Peng Zhang, Bin Liu, Bin Liu, Shuheng Li, Shuheng Li, Rong Sun, Rong Sun, Tongmei Diao, Tongmei Diao, Feng Li, Feng Li

“…Current treatments, including hormone replacement therapy and thyroid transplantation, have limitations due to issues like hormone dosage control and immune rejection. …”
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Acrolein-Triggered Ferroptosis and Protection by Intermittent Fasting via the AMPK/NRF2-CLOCK/BMAL1 Pathway by Yuandie Zhang, Hong Chen, Qianfeng Chen, Margaret Zaitoun, Ying Cheng, Jierong Ge, Qing Feng

“…Acrolein also suppressed the expression of AMP-activated protein kinase (AMPK), nuclear factor erythroid 2-related factor 2 (NRF2), and CLOCK/BMAL1, which were restored by subsequent STS treatments. …”
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Modern approaches to treating drug-resistant epilepsy - ketogenic diet, innovative drugs and neurosurgery by Robert Rzenno, Monika Brzozowska, Wiktoria Wardal, Natalia Furlepa, Karolina Wojciechowska, Marcelina Matuszewska, Katarzyna Wicha, Natalia Sidz, Magdalena Tomaszewska, Wiktoria Jedlikowska

“…Description of the state of knowledge Drug-resistant epilepsy is often associated with disruptions in neuronal activity, changes in protein expression, and imbalances in neurotransmitters. These factors contribute to the lack of response to standard antiepileptic medications. …”
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Molecular genetic markers of breast cancer: current advances in understanding the etiology, prognostic value, and therapeutic opportunities by M. M. Omarov, V. V. Trusova, L. M. Agabekyan, I. R. Gaziev, Z. M. Alibekova, L. A. Aivazyan, E. A. Safarova, A. M. Adzhigulova, A. A. Darmilova, E. K. Khanmukhometova, I. R. Vanova, V. I. Pigareva

“…High diagnostic and prognostic value was found for mutations in the BRCA1/2, PIK3CA,TP53, CHEK2, PALB2, and ESR1 genes, as well as for the expression of PD-L1, TILs (tumor-infiltrating lymphocytes), and Foxp3+ regulatory T cell levels. …”
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POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER AFTER AUTOLOGOUS PERIPHERAL STEM CELL TRANSPLANTATION IN A ADULT PATIENT: CASE REPORT by FZ Piazera, JVP Neto, LHA Ramos, RS Vasconcelos

“…The bone marrow biopsy immunohistochemical analysis showed that the lymphocytes were positive for CD20, according to the immunophenotype below: Flow cytometric immunophenotyping analysis of the specimen revealed that the proportion of surface: 86.58% of the B lymphocytes (1.66% of the total cells analyzed) expressed CD19, CD20 (strong), CD23 (weak), CD45 (strong), CD79b, CD81 and lambda light chain restriction, without expression of CD10, CD38, CD43, CD200, CD305 or other markers investigated. 0.12% were plasma cells without immunophenotypic alterations (ckappa/clambda: 1.47). …”
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Analysis of the CPZ/Wnt4 osteogenic pathway for high-bonding-strength composite-coated magnesium scaffolds through transcriptomics by Zewen Shi, Fang Yang, Tianyu Du, Qian Pang, Chen Liu, Yiwei Hu, Weilai Zhu, Xianjun Chen, Zeming Chen, Baiyang Song, Xueqiang Yu, Zhewei Ye, Lin Shi, Yabin Zhu, Qingjiang Pang

“…Transcriptomic analyses further demonstrated that the PDA-MHA/Mg scaffold upregulated carboxypeptidase Z expression and activated the Wnt-4/β-catenin signaling pathway, thereby promoting bone regeneration. …”
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Efficient endogenous protein labelling in Dictyostelium using CRISPR/Cas9 knock-in and split fluorescent proteins. by Kensuke Yamashita, Tetsuya Muramoto

“…Fluorescent protein tagging is a powerful technique for visualising protein dynamics; however, full-length fluorescent protein knock-in can be inefficient at certain genomic loci, making it challenging to achieve stable and uniform expression. To address this issue, we used CRISPR/Cas9-mediated knock-in strategies with split fluorescent proteins in Dictyostelium discoideum. …”
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Bacteria-Induced Calcite Precipitation for Engineering and Environmental Applications by Purnima Baidya, Bhim Kumar Dahal, Archana Pandit, Dev Raj Joshi

“…This review argues that BCP can be induced by multiple approaches, including urease expressing bacteria and carbonic anhydrase expressing bacteria as well as free enzymes.…”
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A Contention for the Separation of Church and State in Kenya by Samuel Mwangi

“… The separation of church and state in Kenya has always been a polarizing issue due to its contentious nature. A significant problem, often overlooked in research, is the misunderstanding of the wording in the 2010 Constitution and the interpretation of High Court judgments concerning the separation issue. …”
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A two phase ensembled deep learning approach of prominent gene extraction and disease risk prediction by Prajna Paramita DEBATA, Alakananda TRIPATHY, Pournamasi PARHI, Smruti Rekha DAS

“…Determining the optimal model for classification remains a time-consuming nondeterministic polynomial-time hard issue. However, available voluminous gene expression data is too much to handle for the traditional data analysis approaches. …”
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EM Dipeptide Enhances Milk Protein Secretion: Evidence from Integrated Metabolomic and Transcriptomic Analysis by Yuqing Liu, Yuhao Yan, Runjun Yang, Xiaohui Li, Chuang Zhai, Xuan Wu, Xibi Fang, Boqun Liu

“…However, insufficient breast milk remains a serious issue, and bioactive peptides represent a potential strategy to promote lactation. …”
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Institutional framework of youth organization in local self-government units in the Republic of Serbia: Problems and potential solutions by Milenković Dejan, Petrović Agatina

“…The results of the analysis have shown numerous problems resulting from unclear and insufficiently developed provisions of the law on these issues. Additionally, the paper presents comparative solutions for the same issues in certain European Union member states and Western Balkans countries.…”
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Forming Students’ Value-meaningful Attitude to the Socio-cultural Heritage of Religion in Scientific and Pedagogical Discourse by Elena V. Lukashina

“…Background. Currently, the issues of religion and the attitude of society towards it occupy an important place in scientific discourse. …”
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“Les salauds”, un pamphlet d’Alpha Blondy dans une Côte d’Ivoire en crise by Yao Francis KOUAME

“…Reggae music singer, his compositions certainly address issues related to situations taking place in the world, but they also deal with issues related to his country of origin, Ivory Coast. …”
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Freedom of Religion and Gender Equality in Sustainable Development Agenda by Khansadhia Afifah Wardana, Rahayu Rahayu, Sukirno Sukirno

“…Although SDG 2030 has expressed its commitment to respect, protect, and promote fundamental freedoms, including one's religion, and to achieve gender equality, the antagonistic construction between those two issues possibly harm the women’s rights movement and does not adhere to the “no one left behind†principle. …”
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Maḥmūd al-Fanārī’s Life and His Treatise on Ta‘zīr by Şaban Kütük

“…This permissibility situation expressed by al-Fanārī was also severely criticized by some of his contemporaries in their works. …”
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DILATORY INSECURITY, VECTORS OF POPULATIONS MOBILITY AND RESILIENCE CAPACITIES IN THE RURAL COMMUNE OF YALGO IN BURKINA FASO by Wendkouni Ousmane NIKIEMA, Pawendkisgou Isidore YANOGO

“… Context and Background: In West African countries such as Burkina Faso, Mali and Niger, security issues have become the subject of socio-political controversy. …”
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Sentiment Analysis on the PT Pertamina Corruption Case using IndoBERT and RCNN Methods by Wildan Jaya Kusoema, Ichsan Ibrahim

“…The findings have potential applications in real-time digital public opinion monitoring systems for strategic national issues.…”
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The Eloquence of Silence in Taha Hussein’s Al-Ayyam (The Days) by Rooh allah Nasiri

“…Taha Hussein sometimes, using body language, expresses intended meanings and sometimes in silence, hides his pain. …”
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