Breast Implant Illness May Be Rooted in Mast Cell Activation: A Case-Controlled Retrospective Analysis by Èva S. Nagy, BMedSci(Hons), MBBS, PhD, FRACS, Grad Cert (Breast Surgery), Mark Westaway, MBBS, DCH, Grad Dip Allergy, Suzanne Danieletto, BSc, MBBS (Hons), FRCPA, MIAC, Lawrence B. Afrin, MD

“…Given that neoantigenic/xenobiotic exposures commonly trigger dysfunctional MCs in MCAS to heighten aberrant mediator expression driving inflammatory and other issues, further investigation of whether BII represents an implant-driven escalation of preexisting MCAS and whether an MCAS diagnosis flags risk for BII seems warranted.…”
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Survey of transcriptome analyses of hippocampal neurogenesis with focus on adult dentate gyrus stem cells by Laura Micheli, Maurizia Caruso, Giorgio D’Andrea, Daniel Volpe, Manuela Ceccarelli, Felice Tirone

“…This review is focused on transcriptomic studies that have faced these and other NSC issues by analyzing developmental trajectories of neural cells and NSCs gene expression profiles in specific experimental settings of hippocampal neurogenesis, and also in mouse models with deletion or overexpression of specific genes to reproduce neural pathologies.…”
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Assessment of genetically modified sugar beet KWS20‐1 (application GMFF‐2023‐14732) by EFSA Panel on Genetically Modified Organisms (GMO), Josep Casacuberta, Francisco Barro, Albert Braeuning, Ruud deMaagd, Michelle M. Epstein, Thomas Frenzel, Jean‐Luc Gallois, Frits Koning, Antoine Messéan, F. Javier Moreno, Fabien Nogué, Giovanni Savoini, Alan H. Schulman, Christoph Tebbe, Eve Veromann, Michele Ardizzone, Giacomo De Sanctis, Antonio Fernandez Dumont, Arianna Ferrari, Andrea Gennaro, José Ángel Gómez Ruiz, Tilemachos Goumperis, Dafni Maria Kagkli, Aleksandra Lewandowska, Ana M. Camargo, Maria Neri Franco, Pietro Piffanelli, Tommaso Raffaello, Marta Rodrigues, Elena Sánchez‐Brunete

“…These properties were achieved by introducing the cp4 epsps, dmo and pat expression cassettes. The molecular characterisation data and bioinformatic analyses do not identify issues requiring further safety assessment. …”
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Pathogenetic role of IL-4 and IL-13 in atopic dermatitis: The inhibitory pathways by D. Sh. Macharadze

“…The article also discusses issues related to the role of the JAK/STAT signaling pathway and, in particular, the JAK1 protein in development of atopic dermatitis. …”
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Predicting compressive strength of concrete at elevated temperatures and optimizing its mixture proportions by Jinjun Xu, Han Wang, Wenjun Wu, Lang Lin, Yong Yu

“…Predicting concrete behavior under high temperatures and optimizing fire-resistant mix designs remain key challenges in civil engineering. To address the issues to a certain extent, this paper integrates Bayesian prediction with Cuckoo search optimization at material scale. …”
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Integrating Pose Features and Cross-Relationship Learning for Human–Object Interaction Detection by Lang Wu, Jie Li, Shuqin Li, Yu Ding, Meng Zhou, Yuntao Shi

“…Methods: In this paper, we design a Pose-Aware Interaction Network (PAIN) based on transformer architecture and human posture to address these issues through two innovations: A new feature fusion method is proposed, which fuses human pose features and image features early before the encoder to improve the feature expression ability, and the individual motion-related features are additionally strengthened by adding to the human branch; the Cross-Attention Relationship fusion Module (CARM) better fuses the three-branch output and captures the detailed relationship information of HOI. …”
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Cysteine Rich Intestinal Protein 2 is a copper-responsive regulator of skeletal muscle differentiation and metal homeostasis. by Odette Verdejo-Torres, David C Klein, Lorena Novoa-Aponte, Jaime Carrazco-Carrillo, Denzel Bonilla-Pinto, Antonio Rivera, Arpie Bakhshian, Fa'alataitaua M Fitisemanu, Martha L Jiménez-González, Lyra Flinn, Aidan T Pezacki, Antonio Lanzirotti, Luis Antonio Ortiz Frade, Christopher J Chang, Juan G Navea, Crysten E Blaby-Haas, Sarah J Hainer, Teresita Padilla-Benavides

“…Further analyses showed that mCrip2 regulates the expression of genes like MyoD1, essential for muscle differentiation, and metallothioneins in response to copper supplementation. …”
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Topologically associating domains of chromatin on single-cell Hi-C data: a survey of bioinformatic tools and applications in the light of artificial intelligence by Hongqiang Lyu, Yao Li, Xinran Chen, Yuan Liu, Erhu Liu, Xiaoliang Cheng

“…Topologically associating domains (TADs) uncovered on bulk Hi-C data are regarded as fundamental building blocks of a three-dimensional genome, and they are believed to effectively participate in the regulatory programs of gene expression. The computational analysis of TADs on single-cell Hi-C (scHi-C) data in the era of single-cell transcriptomics has received continuous attention since it may provide information beyond that on bulk Hi-C data. …”
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Research on the construction method of temporal knowledge graph for open-pit coal mine slope safety by CHU Yangjing, ZHANG Heng, TANG Ling, HOU Xiaodong

“…This paper aims to address the issues of insufficient temporal knowledge graphs for open-pit coal mine slope safety, difficulties in effectively sharing data resources, and limitations in handling dynamic knowledge. …”
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Institutional Media Freedom in the EU: Implications for Democratic Governance and Social Innovation

“…This fundamental right is integral to the broader scope of freedom of expression, enshrined in international declarations and covenants. …”
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Regional ecological risk assessment for Guangxi (China) based on entropy method and the pressure-capital-vulnerability-response model by Hui Wang

“…As for vulnerability, apart from slope, vegetation, soil and dryness factors, karst distribution index was also incorporated into the expression of final comprehensive eco-environmental vulnerability of Guangxi. …”
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New Functional Fermented Mare’s Milk Product: Biological Assessment in vivo by Elena S. Simonenko, Sergey V. Simonenko, Anna V. Begunova, Andrey N. Petrov, Elena S. Semenovа

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Research on Ship Engine Fuel Consumption Prediction Algorithm Based on Adaptive Optimization Generative Network by Defu Zhang, Yuxuan Song, Jianfeng Gao, Zhenyu Shen, Liangkuan Li, Anren Yao

“…The MD-RAN algorithm is significantly better than the original model in terms of prediction accuracy, stability, and nonlinear expression ability. The R² value can reach 0.9853, and the RMSE and MAE are as low as 1.5801 and 1.1879, respectively. …”
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Molecular Adjuvant Potential of <i>GCSF</i> and <i>MCSF</i> in Starry Flounder Challenged with <i>Streptococcus parauberis</i> by Min-Young Sohn, Gyoungsik Kang, Kyung-Ho Kim, Ha-Jeong Son, Chan-Il Park

“…Quantitative real-time PCR revealed that <i>GCSF</i> is highly expressed in the skin, peripheral blood leukocytes, and muscle, with significant up-regulation in immune organs following <i>Streptococcus parauberis</i> infection; <i>MCSF</i> exhibited a similar tissue-specific expression pattern. …”
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SPECIFIC VOCABULARY IN UKRAINIAN FICTION: FUNCTIONS AND METHODS OF PRESENTATION (ON P.A. ZAHREBELNYI’S NOVELS) by Catherine S. Bondarchuk, Olha A. Chumachenko

“…The article analyzes the peculiarities of specific vocabulary and reveals their functions in various issues related to the novels by Pavel Arkhipovych Zahrebelnyi, one of the most famous writers of the 20th century. …”
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Pathogenicity and virulence of Pseudomonas aeruginosa: Recent advances and under-investigated topics by Jemima Swain, Isabel Askenasy, Rahan Rudland Nazeer, Pok-Man Ho, Edoardo Labrini, Leonardo Mancini, Qingqing Xu, Franziska Hollendung, Isabella Sheldon, Camilla Dickson, Amelie Welch, Adam Agbamu, Camilla Godlee, Martin Welch

“…We also discuss the fact that virulence is a high-risk strategy and touch on how expression of the two main classes of virulence factors is regulated. …”
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Prediction of suicidal attempts among Chinese adolescents with mood disorders: a clinical study using a machine learning approach by Jianbing Li, Yinqiu Zhao, Chi Yang, Wenqing Li, Zhihao Huang, Changhe Fan

“…Results The LGBM model achieved the highest discriminant performance, with an AUC of 0.79 and an accuracy of 0.75, with factors of the emotional expression functioning of non-suicidal self-injury, suicidal planning, peer relationship issues, physician-assessed depression levels, and patient self-reported anxiety and depression levels all demonstrating the highest values in predicting SA. …”
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The Dynamics of Doctor-Patient Communication During Remote Consultations: Qualitative Study Among Norwegian Contract General Practitioners by Børge Lønnebakke Norberg, Bjarne Austad, Eli Kristiansen, Paolo Zanaboni, Linn Okkenhaug Getz

“…Communication becomes too transactional, limiting the chances of addressing more implicit and complex issues, with the risk of missing vital information. …”
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Curcumin-loaded PLGA microparticles integrated with ZnO/GelMA hydrogel microneedles for infectious wound healing and reduction of hypertrophic scars by Yifan Zhang, Ziyi Zhou, Na Liu, Jing Wang, Qingxia Guo, Yong You, Kaiping Mao, Yuanfei Wang, Weina Zhang, Tong Wu

“…Abstract Excessive scarring can impede the normal skin movement, resulting in decreased body flexibility and functional abnormalities. These issues, in turn, impact patients’ daily lives and comfort. …”
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Interpersonal Conflict and Employee Behavior in the Public Sector: Investigating the Role of Workplace Ostracism and Supervisors’ Active Empathic Listening by Hatem Belgasm, Ahmad Alzubi, Kolawole Iyiola, Amir Khadem

“…Using the stressor–emotion model, conservation of resources (COR) theory, and conflict expression (CE) framework, this study examined these relationships through a two-wave survey design. …”
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