Showing 1,181 - 1,200 results of 5,025 for search 'issues expression', query time: 0.12s Refine Results
  1. 1181

    Sustainable Agriculture: The Role of Biostimulants in Enhancing Crop Growth and Resilience by Hasddin Hasddin, , Ulyasniati , Ulyasniati

    Published 2025-04-01
    “…Humic compounds modulate gene expression and activate antioxidant pathways to improve soil fertility and stress tolerance. …”
    Get full text
    Article
  2. 1182

    In vitro hair growth-promoting effects of araliadiol via the p38/PPAR-γ signaling pathway in human hair follicle stem cells and dermal papilla cells by Seokmuk Park, Han Woong Park, Dae Bang Seo, Dae Sung Yoo, Seunghee Bae

    Published 2024-12-01
    “…Specifically, it increased the protein expression of cyclin B1 and Ki67. In HHFSCs, it elevated the expression of hair growth-promoting factors, including CD34, vascular endothelial growth factor (VEGF), and angiopoietin-like 4. …”
    Get full text
    Article
  3. 1183

    The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis by Javier Conde, Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, Rocío García‐Gómez, Berta Casar, Piero Crespo, Xosé R. Bustelo

    Published 2025-01-01
    “…The mevalonate pathway plays an important role in breast cancer and other tumor types. However, many issues remain obscure as yet regarding its mechanism of regulation and action. …”
    Get full text
    Article
  4. 1184

    Assessing the effectiveness of preventing placenta-associated complications in patients with burdened obstetric history and circulating antiphospholipid antibodies by D. R. Eremeeva, M. S. Zainulina

    Published 2024-09-01
    “…The role of antiphospholipid antibody (APA) carriage in the pathogenesis of pregnancy failure is one of the most recently debated issues. To date, no unified therapeutic approach to immunotherapy of antiphospholipid syndrome (APS) in pregnancy exists. …”
    Get full text
    Article
  5. 1185

    Development and characterization of a novel immortalized human vaginal fibroblast cell line for advanced applications in reproductive health by Leong Chi Cheng, Shuoming You, Tingting Ren, Junjun Qiu, Keqin Hua

    Published 2025-04-01
    “…Abstract Background Reproductive health issues related to the vagina, face significant challenges due to the lack of standardized research models. …”
    Get full text
    Article
  6. 1186

    Emerging Roles of GDF15 in Metabolic and Cardiovascular Diseases by Tian Tian, Monan Liu, Peter J. Little, Hans Strijdom, Jianping Weng, Suowen Xu

    Published 2025-01-01
    “…This review summarizes the expression, distribution, structure, processing, and secretion of GDF15. …”
    Get full text
    Article
  7. 1187

    Temperature‐sensitive sodium beta‐glycerophosphate/chitosan hydrogel loaded with all‐trans retinoic acid regulates Pin1 to inhibit the formation of spinal cord injury‐induced rat g... by Rongmou Zhang, Ting Tang, Huafeng Zhuang, Peiwen Wang, Haiming Yu, Hao Xu, Xuedong Yao

    Published 2025-05-01
    “…Mechanistically, ATRA administration blocks the development of glial scars and the activation of the PI3K/AKT/CDK2 pathway by inhibiting Pin1 expression. This study suggests that combining ATRA with a hydrogel to target Pin1 expression may be a promising strategy for treating glial scar formation following SCI.…”
    Get full text
    Article
  8. 1188

    Neuroendocrine tumors of the digestive system: pathologic and molecular characteristics by V. V. Delektorskaya

    Published 2015-06-01
    “…In the light of these criteria, current issues of the nomenclature, as well as systems of grading and staging are discussed. …”
    Get full text
    Article
  9. 1189

    (Un) Critical Pedagogy: Current Priorities and Prospects of Development by Olena Budnyk

    Published 2023-04-01
    “…It is substantiated that various forms of discrimination often arise in the educational setting due to the social or material status of the child's parents, and his/her racial or religious affiliation, that is, they are associated with the rejection of diversity and have an impact on the educational process and personal self-expression in society. The issue of criticality in education must be considered in the modern dimension: in school and student society, teaching and scientific activities, educational management, pedagogical imageology, intercultural education, etc. …”
    Get full text
    Article
  10. 1190

    The impact of alexithymia, anxiety, social pressure, and academic burnout on depression in Chinese university students: an analysis based on SEM by Mingyang Sun, Ming Piao, Zhaona Jia

    Published 2024-12-01
    “…Furthermore, the positive influence of academic burnout on anxiety and depression indicates that excessive academic burdens are significant sources of mental health issues for college students. This research offers new insights into understanding college students’ mental health issues, aiming to provide more comprehensive intervention strategies for their psychological well-being.…”
    Get full text
    Article
  11. 1191
  12. 1192

    Fault Type Recognition and Localization Method for Grounding Electrode Line Based on Modulus Backward Traveling Wave by Xinyang ZHAO, Hongsen ZOU, Chen YANG, Yuqi LI, Botong LI, Siyuan LIU

    Published 2025-02-01
    “…To address the above issues, this paper adopts an active traveling wave injection method, and through analytical calculations, obtains the time-domain expression of the modulus-backward traveling wave at the measuring point at the first end of the ground electrode line after a single-line ground fault, a cross-line fault, a single-line open-circuit fault and a double-line open-circuit fault. …”
    Get full text
    Article
  13. 1193

    Wb5, a novel biomarker for monitoring efficacy and success of mass drug administration programs for Wuchereria bancrofti elimination. by Rachel E Pietrow, Catherine Bjerum, Benjamin G Koudou, Taniawati Supali, Philip J Budge, Peter U Fischer, Thomas B Nutman, Sasisekhar Bennuru

    Published 2025-05-01
    “…As current testing suffers from either sensitivity or specificity levels that fail to meet adopted target product profiles, additional targets that could be used as confirmatory tests or in multiplexed assays could overcome these issues. To this end, bioinformatic analyses coupled with stage-specific expression data for W. bancrofti (Wb) and/or B. malayi (Bm) resulted in the identification of 12 targets that were: 1) present in Wb and/or Bm; 2) had very little to no homology with proteins from other filariae; and 3) were enriched in the microfilarial or L3 stages. …”
    Get full text
    Article
  14. 1194

    5-Azacytidine-Induced Cardiomyocyte Differentiation of Very Small Embryonic-Like Stem Cells by XiaoLin Sun, HongXiao Li, Ye Zhu, Pei Xu, QiSheng Zuo, BiChun Li, Xiang Gu

    Published 2020-01-01
    “…Due to the propensity of stem cells to form tumors, as well as ethical issues surrounding their use, the seed cells used in cardiac biological pacemakers have limitations. …”
    Get full text
    Article
  15. 1195

    MTFSR: Multitemporal and Spatial Feature Reconstruction Denoising Network for Remote Sensing Change Detection by YeKai Cui, Peng Duan, Jinjiang Li

    Published 2025-01-01
    “…Meanwhile, a spatial attention mechanism and discrete cosine transform (DCT) are incorporated to further improve the spatial expression and frequency domain perception of the features. …”
    Get full text
    Article
  16. 1196

    Precise copper ion release and recovery in polycaprolactone nanofiber scaffold: an antibacterial and osteogenic synergistic strategy for guided bone regeneration by Tongbin Liu, Tongbin Liu, Akram Hassan, Matheel Zohair Yousif Alrawas, Caiyun Cui, Zaihan Ariffin

    Published 2025-08-01
    “…IntroductionInfection control and bone regeneration remain major challenges in orthopedic therapy. To address these issues, we developed a multifunctional guided bone regeneration (GBR) nanofibrous material based on electrospun polycaprolactone (PCL). …”
    Get full text
    Article
  17. 1197

    Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics by Shreya Johri, Kevin Bi, Breanna M. Titchen, Jingxin Fu, Jake Conway, Jett P. Crowdis, Natalie I. Vokes, Zenghua Fan, Lawrence Fong, Jihye Park, David Liu, Meng Xiao He, Eliezer M. Van Allen

    Published 2025-03-01
    “…Here, we present a nonparametric statistical method, BEANIE, for differential expression of gene signatures between clinically relevant groups that addresses these issues. …”
    Get full text
    Article
  18. 1198

    Conceptual Framework of Energy-and-Ecology of Indoor Plant Lighting by Sergei A. Rakut’ko

    Published 2018-12-01
    “…The author proposes to expand the range of issues considered in this field and highlight the energy-and-ecology of horticulture (EEH) as a scientific area located at the junction of power engineering and technical subjects, plant physiology, and ecology. …”
    Get full text
    Article
  19. 1199

    Human Amnion-Derived Mesenchymal Stem Cells Promote Osteogenic Differentiation in Human Bone Marrow Mesenchymal Stem Cells by Influencing the ERK1/2 Signaling Pathway by Yuli Wang, Fei Jiang, Yi Liang, Ming Shen, Ning Chen

    Published 2016-01-01
    “…Human amnion-derived mesenchymal stem cells (HAMSCs) are considered to be an important resource in the field of tissue engineering because of their anti-inflammatory properties and fewer ethical issues associated with their use compared with other sources of stem cells. …”
    Get full text
    Article
  20. 1200

    Basolateral Amygdala but Not Medial Prefrontal Cortex Contributes to Chronic Fluoxetine Treatments for PTSD Symptoms in Mice by Ying Hao Yu, Chen Yin Ou, Bai Chuang Shyu, Andrew Chih Wei Huang

    Published 2020-01-01
    “…The Cg1, PrL, IL, and BLA were seemingly to increase c-Fos expression after footshock-induced PTSD symptoms in the situational reminder phase. …”
    Get full text
    Article