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Oncolytic vaccinia virus harboring CLEC2A gene enhances viral replication and antitumor efficacy
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MODERN DIAGNOSTICS AND TREATMENT OF ACUTE STREPTOCOCCAL PHARYNGITIS AND TONSILLITIS IN CHILDREN AND ADULTS
Published 2013-05-01“…It gives recommendations on using an express test for quick and quality diagnostics of infections caused by group A β-hemolytic streptococcus (GABHS) in routine practice. …”
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Purification and expression of a novel bacteriocin, JUQZ-1, against Pseudomonas syringae pv. Actinidiae (PSA), secreted by Brevibacillus laterosporus Wq-1, isolated from the rhizos...
Published 2025-01-01“…The gene of the 01021 protein was cloned into the plasmid pPICZa, and the recombinant bacteriocin was successfully expressed using the Pichia pastoris X33 expression system. …”
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Co-expression of IL-15 and CCL21 strengthens CAR-NK cells to eliminate tumors in concert with T cells and equips them with PI3K/AKT/mTOR signal signature
Published 2025-06-01“…Background Chimeric antigen receptor (CAR)-natural killer (NK) cell therapy has demonstrated safety and feasibility in clinical settings; however, limited efficacy due to intrinsic dysfunction and extrinsic suppression remains an unresolved issue. T cells provide multifaceted support to NK cell-mediated responses. …”
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Effect of Dead-Cell <i>Limosilactobacillus ingluviei</i> on Hematological Parameters and Jejunal Transcriptome Profile in Calves During the Weaning Period
Published 2025-06-01“…Weaning is challenging for dairy calves, frequently resulting in digestive issues. This highlights the importance of implementing appropriate nutritional strategies to enhance gut health and support optimal growth. …”
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Bioinformatics Analysis of Candidate Genes Related to Fat Deposition in Yaks at Different Energy Levels
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Integrative multi-omics approach using random forest and artificial neural network models for early diagnosis and immune infiltration characterization in ischemic stroke
Published 2024-12-01“…BackgroundIschemic stroke (IS) is a significant global health issue, causing high rates of morbidity, mortality, and disability. …”
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Efficacy and safety of PD-1 inhibitors as second-line treatment for advanced squamous esophageal cancer: a systematic review and network meta-analysis with a focus on PD-L1 express...
Published 2025-01-01“…However, there remains no clear consensus on which PD-1 inhibitor provides the best balance between efficacy and safety. To address this key issue in the second-line treatment of ESCC, we conducted a network meta-analysis (NMA) with a focus on OS benefits, particularly in patients with different levels of PD-L1 expression.MethodsA systematic search of relevant literature was conducted in Web of Science, Embase, PubMed, and Cochrane Library, covering publications from the inception of these database to June 2024. …”
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Ethical Self-Reflection in Papers, Please
Published 2019-12-01“…This article argues that multiple endings and narrative memory within interactive narratives can engender ethical self-reflection in relationship with broader discourses surrounding controversial issues. It introduces the term ‘expressed self’ to describe this process. …”
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L’aménagement des gares du Grand Paris Express face à la gouvernance complexe de la région-capitale. L’instrument du comité de pôle comme réponse pour une meilleure coordination de...
Published 2021-09-01“…There is a strong interest from the research and professional communities in issues related to the design of more sustainable modes of urbanization, less costly in travel and less dependent on the automobile. …”
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CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression
Published 2023-08-01“…Background Despite significant progress in the development of T cell-engaging therapies for various B-cell malignancies, a high medical need remains for the refractory disease setting, often characterized by suboptimal target levels.Methods To address this issue, we have developed a 65-kDa multispecific antibody construct, CLN-978, with affinities tuned to optimize the killing of low-CD19 expressing tumor cells. …”
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The Mediating Roles of Self-Compassion and Emotion Regulation in the Relationship Between Psychological Resilience and Mental Health Among College Teachers
Published 2024-12-01“…These findings underscore the necessity for culturally sensitive mental health interventions within educational institutions in Saudi Arabia.Keywords: psychological resilience, mental health, cognitive reappraisal, expressive symptoms, emotion regulation, college teachers, Saudi Arabia…”
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Removal of Expression of Concern for ‘Lipid-lowering therapy in patients with coronary heart disease: an Italian real-life survey. Results from the Survey on Risk FactOrs and Cardi...
Published 2025-01-01“…Results from the Survey on Risk FactOrs and CardiovascuLar secondary prevention and drug strategieS (SOFOCLES) in Italy’ by Caterina Oriana Aragona et al., Monaldi Arch Chest Dis, 2024, Accepted Manuscript, https://doi.org/10.4081/monaldi.2024.2972 IF: 1.1 Q4 NA The Editors and Publisher of the Monaldi Archives for Chest Disease are publishing this removal of expression of concern to inform readers that the investigation is complete and all earlier issues have been addressed. …”
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