miR-23b is a negative regulator of tumor suppressing PTPRG in colorectal cancer by Hong Duan, Jianhu Jia, Tingting Wang, Ghulam Jilany Khan, Li Wang, Sirong Zhang, Jianhua Yang, Chenghui He, Fei Li, Henggui Hu, Kefeng Zhai

“…Colorectal cancer (CRC) is among top most common cancers with high mortality rate and major health issue yet to resolve across the globe. miR-23b is an oncogene in many cancers including CRC. …”
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Sulfhydrylated albumin mitigates Acetaminophen-induced liver injury by restoring the integrated H2S-albumin thiol antioxidant network by Xin Wang, Yang Sui, Rui Jiang, Yijun Xu, Mika Suda, Jie Cheng, Yingyu Zhang, Zhuheng Shi, Jianglin Fan, Jian Yao

“…Acetaminophen (APAP) overdose is the leading cause of acute liver failure and a major global health issue. APAP hepatotoxicity is primarily driven by oxidative stress resulting from the depletion of hepatic glutathione (GSH). …”
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Exploring clinical reasoning development perspectives among final year medical students by Gul Mehar Javaid Bukhari, Abel Jacobus Pienaar, Gideon Victor, Sara Khan, Javeria Saleem

“…The categories represented appreciating and devaluating expressions of medical students for the development of clinical reasoning. …”
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Time-Averaged Energy Flow and Momentum of Electromagnetic Waves in Homogeneous Isotropic Linear Media by Quanzhi Kougong, Jiangwei Chen

“…There exist multiple different even non-equivalent expressions describing characteristics of electromagnetic wave energy flow and momentum in media, which makes the issue confusing. …”
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Advancing mental health assessment: indigenous psychometric tools for personality disorders in Pakistan by Akhtar Sherin, Abdul Wahab Yousafzai

“…Addressing this critical gap, this thematic issue introduces ten meticulously developed Urdu-language scales for diagnosing various personality disorders. …”
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Immobilization of Silver Nanoparticles with Defensive Gum of <i>Moringa oleifera</i> for Antibacterial Efficacy Against Resistant Bacterial Species from Human Infections by Liaqat Ali, Nisar Ahmad, Muhammad Nazir Uddin, Mostafa A. Abdel-Maksoud, Hina Fazal, Sabiha Fatima, Mohamed A. El-Tayeb, Bushra Hafeez Kiani, Wajid Khan, Murad Ali Rahat, Mohammad Ali, Yaqub Khan, Kamran Rauf, Salman Khan, Sami Ullah, Tanveer Ahmad, Afshan Salam, Sajjad Ahmad

“…Alternative strategies are needed to overcome this issue. <b>Objectives</b>: In this study, a novel strategy was adopted to suppress the growth of resistant pathogens through immobilization of silver nanoparticles (AgNPs) in gum of <i>Moringa oleifera</i>. …”
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Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms by Mie Suzuki Okutani, Shinya Okamura, Tang Gis, Hitomi Sasaki, Suni Lee, Akiho Kashiwabara, Simon Goto, Mai Matsumoto, Mayuko Yamawaki, Toshiaki Miyazaki, Tatsuya Nakagawa, Masahito Ikawa, Wataru Kamitani, Shiro Takekawa, Koichi Yamanishi, Hirotaka Ebina

“…Furthermore, we confirmed the safety of BK2102 using transgenic (Tg) mice expressing human ACE2 (hACE2) that are highly susceptible to SARS-CoV-2. …”
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Psychopathological Comorbidities in Children and Adolescents with Feeding and Eating Disorders: An Italian Clinical Study by Maria Califano, Jacopo Pruccoli, Oliviero Cavallino, Alessandra Lenzi, Antonia Parmeggiani

“…Objectives: Feeding and eating disorders (FED) represent a major public health issue and are the second leading cause of death among psychiatric conditions in children and adolescents. …”
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Multi-Focused Acoustic Radiation Force Impulse Modulation of Murine Hepatic Xenografts Enhances Nanoscale DOX@Lip Delivery and Therapeutic Effect by Wu S, Wang C

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Integration of Network Pharmacology, Transcriptomics, and Metabolomics Strategies to Uncover the Mechanism of Chaihuang Qingfu Pill in Treating Sepsis-Induced Liver Injury by Zhang C, Chen F, Jiang Y, Deng J, Yan X, Yin X, Su B, Liu W

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CD8+ T Cell-Derived Perforin Exacerbates Dysbiosis and Inflammatory Bowel Disease via &amp;beta;-Hydroxybutyrate Suppression in Mouse Colonic Epithelium by Huang S, Pan L, Li M, Pang S, Tian Y, Shi W, Zong Y, Zhang D, Tian D

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Preclinical Evaluation of a B7-H3 Targeting Antibody Enhancing NK Cell-Mediated Cytotoxicity for Ovarian Cancer Treatment by Hagelstein I, Mattern S, Wang K, Haueisen YE, Greiner SM, Englisch A, Staebler A, Singer S, Lutz MS

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Exploring Salvia miltiorrhiza&amp;rsquo;s Therapeutic Effects on Adenomyosis by Inhibiting TNF-&amp;alpha;/HIF-1&amp;alpha;/IL-17-Driven Inflammatory Cascade: Mechanistic Insights... by Yang Q, Hong J, Zheng X, Liu X, Lin H, Chen L, Zhong F, Zhang Q, Jiang J, Sun P

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Development of an Early-Warning Model for Predicting the Capecitabine-Induced Diarrhea by Liu Z, Qiu S, Xu Y, Wang X, Sun J, Cui L, Ye L, Liang Z, Gao S, Chen W, Wang Z

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Astragaloside IV Attenuates Chronic Prostatitis by Activating Keap1/Nrf2/HO-1 Pathway: Suppressing Ferroptosis and Enhancing Antioxidant Defense by Shi J, Xuan Y, Zhang Q, Chen J, Zhu W, Zhang H, Duan Y

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Construction of Cationic Carbon Dots Carrying Survivin siRNA Delivery System and Its Active Targeting Therapy for Liver Cancer by Xue W, Du J, Wei Y, Zhou S, Wang S, Yang Y, Chen L, Yu S

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Modified Huanjingjian Prevents Chemotherapy-Induced Alopecia by Inhibiting Genomic DNA Methylation of the Wnt Signaling Pathway in Mice by Liu X, Du T, Xi R, Cheng L, Wang Y, Lu H, Guo D, Zhu J, Liu T, Li F

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Exosomal BMPR2 Macromolecule Facilitates Alveolar Epithelial Cell Repair Through Functional Complex Formation with BMPR1B in Acute Lung Injury by Yun X, Chen Z, Li F, Shen F, Zhang L, Yuan J

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Quantitative Proteomic Study Reveals Amygdalin Alleviates Liver Fibrosis Through Inhibiting mTOR/PDCD4/JNK Pathway in Hepatic Stellate Cells by Huang H, Ru SJ, Chen JM, Liu W, Fang SH, Liu Q, Meng Q, Liu P, Zhou H

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Exosomes Derived From Human Mesenchymal Stem Cells Mitigate Follicular Interstitial Cell Ferroptosis via the miR-26a-5p/PTEN/GPX4 Axis in Rats with Chemotherapy-Induced Premature O... by Chen J, Huo X, Qian M, Xue Q, He Y, Xu P, Wang Y, Tang X, Luo Q, Bao H, Xiong Y

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