Showing 301 - 320 results of 5,025 for search 'issues expression', query time: 0.09s Refine Results
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    Development of a versatile oncolytic virus platform for local intra-tumoural expression of therapeutic transgenes. by Nalini Marino, Sam Illingworth, Prithvi Kodialbail, Ashvin Patel, Hugo Calderon, Rochelle Lear, Kerry D Fisher, Brian R Champion, Alice C N Brown

    Published 2017-01-01
    “…Modifying oncolytic viruses to produce effective cancer therapies is challenging as encoding transgenes often attenuates virus activity or prevents systemic delivery in patients due to the risk of off-target expression of transgenes in healthy tissues. To overcome these issues we aimed to generate a readily modifiable virus platform using the oncolytic adenovirus, enadenotucirev. …”
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  3. 303

    BioLake: an RNA expression analysis framework for prostate cancer biomarker powered by data lakehouse by Qiaowang Li, Yaser Gamallat, Jon George Rokne, Tarek A. Bismar, Reda Alhajj

    Published 2025-02-01
    “…The only pre-built-in dataset of BioLake in the first public version is TCGA-PRAD mRNA expression data for prostate cancer research, which is the primary focus of the development team of BioLake. …”
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    Expression of Brain-Derived Neurotrophic Factor (BDNF) Increases the Resistance of Neurons to Death in the Postresuscitation Period by I. V. Ostrova, M. Sh. Avrushchenko

    Published 2015-07-01
    “…The intensity of BDNF expression was estimated from the mean optical density. …”
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  6. 306

    A Validation Tool (VaPCE) for Postcoordinated SNOMED CT Expressions: Development and Usability Study by Tessa Ohlsen, Viola Hofer, Josef Ingenerf

    Published 2025-02-01
    “…To address this, SNOMED CT allows postcoordination, where users combine precoordinated concepts with new expressions. Despite SNOMED CT’s potential, the creation and validation of postcoordinated expressions (PCEs) remain challenging due to complex syntactic and semantic rules. …”
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  7. 307

    Automated characterization and analysis of expression compatibility between regulatory sequences and metabolic genes in Escherichia coli by Xiao Wen, Jiawei Lin, Chunhe Yang, Ying Li, Haijiao Cheng, Ye Liu, Yue Zhang, Hongwu Ma, Yufeng Mao, Xiaoping Liao, Meng Wang

    Published 2024-12-01
    “…Our study aims not only to provide a detailed guide for fine-tuning gene expression in the metabolic engineering of Escherichia coli but also to deepen our understanding of the compatibility issues between regulatory sequences and target genes.…”
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    Reactions to School Violence in an Online Newspaper: A Thematic Analysis of VnExpress Users’ Comments by Manh Hung Doan, Vu Diep Le

    Published 2024-11-01
    “…This article aims to examine how online newspaper readers react to school violence through 4,364 comments extracted from 36 news articles tagged "bạo lực học đường" (school violence) from September to December 2023 in the Education category on VnExpress, which is the most-read online newspaper in Vietnam and is known to prioritize objectivity and "readers first" philosophy. …”
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    The Problem of Freedom of Expression in the Public Sphere of Social Media: Descriptive Analysis of the Echo Chamber Effect by Hüseyin Köse, Bahar Balcı Aydoğan

    Published 2024-10-01
    “…This is one of the biggest barriers to the development of a free and democratic environment for ideas and beliefs, and it is crucial for the democratic perspective on the freedom of expression on social media. This issue is a serious problem because the oppressive view and opinion environment strengthens practices that exclude diversity. …”
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    Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration by Yu-Fan Chen, Chien-Wei Lee, Yi-Shuan J. Li, Wei-Ting Lin, Hsiao-Yun Chen, Yu-Chuan Chen, Chia-Hao Lin, Jennifer Hui-Chun Ho, Li-Fan Lu, Shu Chien, Oscar Kuang-Sheng Lee

    Published 2025-06-01
    “…Here, to address this issue, we induced injury and performed single-cell RNA sequencing on individual cells in skeletal muscle at different time points. …”
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    Protective Effect of Astaxanthin on Liver Fibrosis through Modulation of TGF-β1 Expression and Autophagy by Miao Shen, Kan Chen, Jie Lu, Ping Cheng, Ling Xu, Weiqi Dai, Fan Wang, Lei He, Yan Zhang, Wang Chengfen, Jingjing Li, Jing Yang, Rong Zhu, Huawei Zhang, Yuanyuan Zheng, Yingqun Zhou, Chuanyong Guo

    Published 2014-01-01
    “…Liver fibrosis is a common pathway leading to cirrhosis and a worldwide clinical issue. Astaxanthin is a red carotenoid pigment with antioxidant, anticancer, and anti-inflammatory properties. …”
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    Linguistic Typology in Motion Events: Expression of Motion Events in Translated Versions of Turkish and English Novels by Cemre İşler

    Published 2022-12-01
    “…Rather than a strict binary typology, the present study raises an issue that languages can vary within the same typological class, and we cannot take it for granted that languages belong strictly to one group of language. …”
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    Mixture of Emotion Dependent Experts: Facial Expressions Recognition in Videos Through Stacked Expert Models by Ali N. Salman, Karen Rosero, Lucas Goncalves, Carlos Busso

    Published 2025-01-01
    “…Recent advancements in <italic>dynamic facial expression recognition</italic> (DFER) have predominantly utilized static features, which are theoretically inferior to dynamic features. …”
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    Dynamic time-varying transfer function for cancer gene expression data feature selection problem by Hao-Ming Song, Yu-Cai Wang, Jie-Sheng Wang, Yu-Wei Song, Shi Li, Yu-Liang Qi, Jia-Ning Hou

    Published 2025-03-01
    “…Feature selection (FS) serves as a crucial preprocessing step in addressing these data mining challenges. To tackle the issue of FS in cancer gene expression data, a novel transfer function structure known as the dynamic time-varying transfer function was proposed. …”
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